Trial Title:
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
NCT ID:
NCT05552222
Condition:
Multiple Myeloma
Conditions: Official terms:
Multiple Myeloma
Neoplasms, Plasma Cell
Dexamethasone
Lenalidomide
Daratumumab
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Teclistamab
Description:
Teclistamab will be administered as SC injection.
Arm group label:
Teclistamab, Daratumumab SC, and Lenalidomide (Tec-DR)
Other name:
JNJ-64007957
Intervention type:
Drug
Intervention name:
Daratumumab
Description:
Daratumumab will be administered as SC injection.
Arm group label:
Daratumumab SC, Lenalidomide, and Dexamethasone (DRd)
Arm group label:
Talquetamab, Daratumumab SC, and Lenalidomide (Tal-DR)
Arm group label:
Teclistamab, Daratumumab SC, and Lenalidomide (Tec-DR)
Intervention type:
Drug
Intervention name:
Lenalidomide
Description:
Lenalidomide will be administered orally.
Arm group label:
Daratumumab SC, Lenalidomide, and Dexamethasone (DRd)
Arm group label:
Talquetamab, Daratumumab SC, and Lenalidomide (Tal-DR)
Arm group label:
Teclistamab, Daratumumab SC, and Lenalidomide (Tec-DR)
Intervention type:
Drug
Intervention name:
Dexamethasone
Description:
Dexamethasone will be administered either orally or intravenously (IV).
Arm group label:
Daratumumab SC, Lenalidomide, and Dexamethasone (DRd)
Intervention type:
Drug
Intervention name:
Talquetamab
Description:
Talquetamab will be administered as SC injection.
Arm group label:
Talquetamab, Daratumumab SC, and Lenalidomide (Tal-DR)
Other name:
JNJ-64407564
Summary:
The purpose of this study is to compare the efficacy of teclistamab in combination with
daratumumab and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab and
lenalidomide (Tal-DR) versus daratumumab, lenalidomide, dexamethasone (DRd).
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Have a diagnosis of multiple myeloma according to the International Myeloma Working
Group (IMWG) diagnostic criteria
- Be newly diagnosed and not considered a candidate for high-dose chemotherapy with
autologous stem cell transplant (ASCT) due to: ineligible due to advanced age OR;
ineligible due to the presence of comorbid condition(s) likely to have a negative
impact on tolerability of high-dose chemotherapy with ASCT OR; deferral of high-dose
chemotherapy with ASCT as initial treatment
- Have an Eastern Cooperative Oncology Group (ECOG) performance status score of 0 to 2
- A participant must agree not to be pregnant, breastfeeding, or planning to become
pregnant while enrolled in this study or within 6 months after the last dose of
study treatment
- A participant must agree not to plan to father a child while enrolled in this study
or within 100 days after the last dose of study treatment
Exclusion Criteria:
- Received any prior therapy for multiple myeloma or smoldering myeloma other than a
short course of corticosteroids (not to exceed total of 160 milligrams [mg]
dexamethasone or equivalent). In addition, received a cumulative dose of systemic
corticosteroids equivalent to greater than or equals to (>=) 20 mg of dexamethasone
within 14 days before randomization
- Had plasmapheresis within 28 days of randomization
- Had a stroke, transient ischemic attack, or seizure within 6 months prior to
randomization
- Known allergies, hypersensitivity, or intolerance to teclistamab or talquetamab
excipients
- Known contraindications to the use of daratumumab or lenalidomide per local
prescribing information
- Myeloma Frailty Index of >=2 with the exception of participants who have a score of
2 based on age alone
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Royal Prince Alfred Hospital
Address:
City:
Camperdown
Zip:
2050
Country:
Australia
Status:
Recruiting
Facility:
Name:
Barwon Health - University Hospital Geelong
Address:
City:
Geelong
Zip:
3220
Country:
Australia
Status:
Recruiting
Facility:
Name:
Liverpool Hospital
Address:
City:
Liverpool
Zip:
2170
Country:
Australia
Status:
Recruiting
Facility:
Name:
Sir Charles Gairdner Hospital
Address:
City:
Nedlands
Zip:
6009
Country:
Australia
Status:
Recruiting
Facility:
Name:
Calvary Mater Newcastle Hospital
Address:
City:
New South Wales
Zip:
2298
Country:
Australia
Status:
Recruiting
Facility:
Name:
Wollongong Hospital
Address:
City:
Wollongong
Zip:
2500
Country:
Australia
Status:
Recruiting
Facility:
Name:
Princess Alexandra Hospital
Address:
City:
Woolloongabba
Zip:
4102
Country:
Australia
Status:
Recruiting
Facility:
Name:
Ordensklinikum Linz GmbH Elisabethinen
Address:
City:
Linz
Zip:
4020
Country:
Austria
Status:
Recruiting
Facility:
Name:
SCRI CCCIT gem GmbH
Address:
City:
Salzburg
Zip:
5020
Country:
Austria
Status:
Recruiting
Facility:
Name:
Medical University Vienna
Address:
City:
Vienna
Zip:
1090
Country:
Austria
Status:
Recruiting
Facility:
Name:
Institut Jules Bordet
Address:
City:
Anderlecht
Zip:
1070
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Ghent University Hospital
Address:
City:
Gent
Zip:
9000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Jolimont
Address:
City:
Haine Saint Paul La Louviere
Zip:
7100
Country:
Belgium
Status:
Completed
Facility:
Name:
Az Groeninge
Address:
City:
Kortrijk
Zip:
8500
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Universitair Ziekenhuis Leuven
Address:
City:
Leuven
Zip:
3000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
GZA Ziekenhuizen- Campus St Augustinus
Address:
City:
Wilrijk
Zip:
2610
Country:
Belgium
Status:
Completed
Facility:
Name:
Fundacao Pio XII
Address:
City:
Barretos
Zip:
14784 400
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Santa Casa de Misericordia de Belo Horizonte
Address:
City:
Belo Horizonte
Zip:
30150 320
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Liga Paranaense de Combate ao Cancer
Address:
City:
Curitiba
Zip:
81520-060
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Instituto Do Cancer Do Ceara
Address:
City:
Fortaleza
Zip:
60430-230
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Liga Norte Riograndense Contra O Cancer
Address:
City:
Natal
Zip:
59062-000
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Complexo Hospitalar de Niteroi
Address:
City:
Niteroi
Zip:
24030-103
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital De Clinicas De Porto Alegre
Address:
City:
Porto Alegre
Zip:
90035 903
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP
Address:
City:
Ribeirao Preto
Zip:
14051-140
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Sao Rafael
Address:
City:
Salvador
Zip:
41235-190
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Nove de Julho
Address:
City:
Sao Paulo
Zip:
01409-902
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinica Medica Sao Germano S/S LTDA
Address:
City:
Sao Paulo
Zip:
04537-081
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Das Clinicas Da Faculdade De Medicina Da USP
Address:
City:
Sao Paulo
Zip:
05403-000
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Arthur J. E. Child Comprehensive Cancer Centre
Address:
City:
Calgary
Zip:
T2N 5G2
Country:
Canada
Status:
Recruiting
Facility:
Name:
Cross Cancer Institute
Address:
City:
Edmonton
Zip:
T6G 1Z2
Country:
Canada
Status:
Recruiting
Facility:
Name:
CHU de Quebec L Hotel Dieu de Quebec
Address:
City:
Quebec
Zip:
G1J 1Z4
Country:
Canada
Status:
Recruiting
Facility:
Name:
Peking University First Hospital
Address:
City:
Beijing
Zip:
100034
Country:
China
Status:
Recruiting
Facility:
Name:
Changzhou No 2 Peoples Hospital
Address:
City:
Chang Zhou
Zip:
213004
Country:
China
Status:
Recruiting
Facility:
Name:
The First Hospital of Jilin University
Address:
City:
Changchun
Zip:
130061
Country:
China
Status:
Recruiting
Facility:
Name:
The Second Xiangya Hospital of Central South Hospital
Address:
City:
Changsha
Zip:
410011
Country:
China
Status:
Recruiting
Facility:
Name:
Beijing Chaoyang Hospital
Address:
City:
Chaoyang District
Zip:
100020
Country:
China
Status:
Recruiting
Facility:
Name:
Sichuan Provincial Peoples Hospital
Address:
City:
Chengdu
Zip:
610072
Country:
China
Status:
Recruiting
Facility:
Name:
Chongqing University Cancer Hospital
Address:
City:
Chongqing
Zip:
400030
Country:
China
Status:
Recruiting
Facility:
Name:
Fujian Meidical University Union Hospital
Address:
City:
Fu Zhou
Zip:
350001
Country:
China
Status:
Recruiting
Facility:
Name:
Nanfang Hospital
Address:
City:
Guangzhou
Zip:
510515
Country:
China
Status:
Recruiting
Facility:
Name:
Sun Yat -Sen University Cancer Center
Address:
City:
Guangzhou
Zip:
511363
Country:
China
Status:
Recruiting
Facility:
Name:
The Second Affiliated Hospital of Zhejiang University
Address:
City:
Hang Zhou
Zip:
310003
Country:
China
Status:
Recruiting
Facility:
Name:
No.1 Affiliated Hospital, Medical College of Zhejiang University
Address:
City:
Hangzhou
Zip:
310003
Country:
China
Status:
Recruiting
Facility:
Name:
Harbin medical university cancer hospital
Address:
City:
Harbin
Zip:
150081
Country:
China
Status:
Recruiting
Facility:
Name:
Qilu Hospital of Shandong University
Address:
City:
Jinan
Zip:
250012
Country:
China
Status:
Recruiting
Facility:
Name:
Zhongda Hospital Southeast University
Address:
City:
Nan Jing
Zip:
214135
Country:
China
Status:
Recruiting
Facility:
Name:
The First Affiliated Hospital of Guangxi Medical University
Address:
City:
Nan Ning Shi
Zip:
530021
Country:
China
Status:
Recruiting
Facility:
Name:
The First Affliated Hospital Of Nanchang University
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Recruiting
Facility:
Name:
Ruijin Hospital Shanghai Jiao Tong University
Address:
City:
Shanghai
Zip:
200025
Country:
China
Status:
Recruiting
Facility:
Name:
Renji Hospital, Shanghai Jiaotong University School of Medicine
Address:
City:
Shanghai
Zip:
200127
Country:
China
Status:
Recruiting
Facility:
Name:
Shanghai Fourth People s Hospital
Address:
City:
Shanghai
Zip:
200434
Country:
China
Status:
Recruiting
Facility:
Name:
Peking University Shenzhen Hospital
Address:
City:
Shen Zhen Shi
Zip:
518036
Country:
China
Status:
Recruiting
Facility:
Name:
Shengjing Hospital Of China Medical University
Address:
City:
Shenyang
Zip:
110022
Country:
China
Status:
Recruiting
Facility:
Name:
Institute of Hematology and Blood Diseases Hospital
Address:
City:
Tian Jin
Zip:
300020
Country:
China
Status:
Recruiting
Facility:
Name:
Tianjin Medical University Cancer Institute and Hospital
Address:
City:
Tianjin
Zip:
300060
Country:
China
Status:
Recruiting
Facility:
Name:
The First Affiliated Hospital of Wenzhou Medical University
Address:
City:
Wenzhou
Zip:
325000
Country:
China
Status:
Recruiting
Facility:
Name:
Wuhan Tongji Hospital Tongji Medical College
Address:
City:
WuHan
Zip:
430032
Country:
China
Status:
Recruiting
Facility:
Name:
The Second Affiliated Hospital of Xi'an Jiaotong University
Address:
City:
Xi' An
Zip:
710004
Country:
China
Status:
Recruiting
Facility:
Name:
Henan Cancer Hospital
Address:
City:
Zhengzhou
Zip:
450008
Country:
China
Status:
Recruiting
Facility:
Name:
Fakultni nemocnice Brno
Address:
City:
Brno - Bohunice
Zip:
625 00
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Fakultni nemocnice Hradec Kralove
Address:
City:
Hradec Kralove
Zip:
500 05
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Fakultni nemocnice Olomouc
Address:
City:
Olomouc
Zip:
779 00
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Fakultni Nemocnice Ostrava
Address:
City:
Ostrava
Zip:
708 52
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Fakultni nemocnice Plzen
Address:
City:
Plzen
Zip:
304 60
Country:
Czechia
Status:
Recruiting
Facility:
Name:
VFN v Praze
Address:
City:
Praha
Zip:
128 08
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Aalborg University Hospital
Address:
City:
Aalborg
Zip:
9000
Country:
Denmark
Status:
Recruiting
Facility:
Name:
Regionshospitalet Godstrup
Address:
City:
Herning
Zip:
7400
Country:
Denmark
Status:
Recruiting
Facility:
Name:
Zealand University Hospital
Address:
City:
Roskilde
Country:
Denmark
Status:
Recruiting
Facility:
Name:
Vejle Sygehus
Address:
City:
Vejle
Zip:
7100
Country:
Denmark
Status:
Recruiting
Facility:
Name:
APHP - Hopital Henri Mondor
Address:
City:
Creteil
Zip:
94010
Country:
France
Status:
Recruiting
Facility:
Name:
Hopital Claude Huriez
Address:
City:
Lille
Zip:
59000
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Nantes
Address:
City:
Nantes
Zip:
44093
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Hopital Saint Antoine
Address:
City:
PARIS cedex 12
Zip:
75012
Country:
France
Status:
Recruiting
Facility:
Name:
CHU de Bordeaux - Hospital Haut-Leveque
Address:
City:
Pessac cedex
Zip:
33604
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Lyon Sud
Address:
City:
Pierre-Benite
Zip:
69310
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Poitiers - Hopital la Miletrie
Address:
City:
Poitiers
Zip:
86021
Country:
France
Status:
Recruiting
Facility:
Name:
CHU de Rennes - Hopital Pontchaillou
Address:
City:
Rennes
Zip:
35033
Country:
France
Status:
Recruiting
Facility:
Name:
Institut de Cancerologie Strasbourg Europe ICANS
Address:
City:
Strasbourg
Zip:
67200
Country:
France
Status:
Recruiting
Facility:
Name:
Institut Universitaire du Cancer Toulouse Oncopole
Address:
City:
Toulouse
Zip:
31000
Country:
France
Status:
Recruiting
Facility:
Name:
Helios Kliniken Berlin Buch Gmbh
Address:
City:
Berlin
Zip:
13125
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Halle Saale
Address:
City:
Halle (Saale)
Zip:
06120
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinik Hamburg-Eppendorf
Address:
City:
Hamburg
Zip:
20251
Country:
Germany
Status:
Recruiting
Facility:
Name:
Klinikum Nuernberg Nord
Address:
City:
Nuernberg
Zip:
90419
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II,
Address:
City:
Tübingen
Zip:
72076
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Wuerzburg
Address:
City:
Wurzburg
Zip:
97080
Country:
Germany
Status:
Recruiting
Facility:
Name:
Alexandra General Hospital of Athens
Address:
City:
Athens Attica
Zip:
115 28
Country:
Greece
Status:
Recruiting
Facility:
Name:
G Papanikolaou Hospital of Thessaloniki
Address:
City:
Thessalonikis
Zip:
570 10
Country:
Greece
Status:
Recruiting
Facility:
Name:
Anticancer Hospital of Thessaloniki Theageneio
Address:
City:
Thessaloniki
Zip:
546 39
Country:
Greece
Status:
Recruiting
Facility:
Name:
Rambam Medical Center
Address:
City:
Haifa
Zip:
3109601
Country:
Israel
Status:
Recruiting
Facility:
Name:
Shaare Zedek Medical Center
Address:
City:
Jerusalem
Zip:
9103102
Country:
Israel
Status:
Recruiting
Facility:
Name:
Rabin
Address:
City:
Petah Tikva
Zip:
49100
Country:
Israel
Status:
Recruiting
Facility:
Name:
Sheba Medical Center
Address:
City:
Ramat Gan
Zip:
52621
Country:
Israel
Status:
Recruiting
Facility:
Name:
Tel Aviv Sourasky Medical Center
Address:
City:
Tel Aviv Yafo
Zip:
6423906
Country:
Israel
Status:
Recruiting
Facility:
Name:
ASST Papa Giovanni XXIII Bergamo
Address:
City:
Bergamo
Zip:
24127
Country:
Italy
Status:
Recruiting
Facility:
Name:
A O U Sant Orsola Malpighi
Address:
City:
Bologna
Zip:
40138
Country:
Italy
Status:
Recruiting
Facility:
Name:
Careggi University Hospital
Address:
City:
Firenze
Zip:
50134
Country:
Italy
Status:
Recruiting
Facility:
Name:
Ospedale San Raffaele
Address:
City:
Milan
Zip:
20132
Country:
Italy
Status:
Recruiting
Facility:
Name:
IRCCS Policlinico San Matteo, Università degli studi di Pavi
Address:
City:
Pavia
Zip:
27100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Universita Degli Studi di Roma Tor Vergata
Address:
City:
Roma
Zip:
00133
Country:
Italy
Status:
Recruiting
Facility:
Name:
Istituto Clinico Humanitas
Address:
City:
Rozzano
Zip:
20089
Country:
Italy
Status:
Recruiting
Facility:
Name:
Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino
Address:
City:
Torino
Zip:
10126
Country:
Italy
Status:
Recruiting
Facility:
Name:
Juntendo University Hospital
Address:
City:
Bunkyo-Ku
Zip:
113-8431
Country:
Japan
Status:
Recruiting
Facility:
Name:
Chiba Cancer Center
Address:
City:
Chiba
Zip:
260 0801
Country:
Japan
Status:
Recruiting
Facility:
Name:
Kameda Medical Center
Address:
City:
Chiba
Zip:
296-0041
Country:
Japan
Status:
Recruiting
Facility:
Name:
National Hospital Organization Mito Medical Center
Address:
City:
Higashiibaraki-gun
Zip:
311-3193
Country:
Japan
Status:
Recruiting
Facility:
Name:
Kansai Medical University Hospital
Address:
City:
Hirakata
Zip:
573-1191
Country:
Japan
Status:
Recruiting
Facility:
Name:
Hyogo Medical University Hospital
Address:
City:
Hyôgo
Zip:
663-8501
Country:
Japan
Status:
Recruiting
Facility:
Name:
Saitama Medical University Hospital
Address:
City:
Iruma-gun
Zip:
350-0495
Country:
Japan
Status:
Recruiting
Facility:
Name:
Tokai University Hospital
Address:
City:
Kanagawa
Zip:
259-1193
Country:
Japan
Status:
Recruiting
Facility:
Name:
Kanazawa University Hospital
Address:
City:
Kanazawa
Zip:
920-8641
Country:
Japan
Status:
Recruiting
Facility:
Name:
Kumamoto University Hospital
Address:
City:
Kumamoto-shi
Zip:
860-8556
Country:
Japan
Status:
Recruiting
Facility:
Name:
Matsuyama Red Cross Hospital
Address:
City:
Matsuyama-City
Zip:
790-8524
Country:
Japan
Status:
Recruiting
Facility:
Name:
National Hospital Organization Nagasaki Medical Center
Address:
City:
Nagasaki
Zip:
856-8562
Country:
Japan
Status:
Recruiting
Facility:
Name:
National Hospital Organization Okayama Medical Center
Address:
City:
Okayama
Zip:
701-1192
Country:
Japan
Status:
Recruiting
Facility:
Name:
Osaka Metropolitan University Hospital
Address:
City:
Osaka
Zip:
545 8586
Country:
Japan
Status:
Recruiting
Facility:
Name:
National Hospital Organization Hokkaido Cancer Center
Address:
City:
Sapporo
Zip:
003-0804
Country:
Japan
Status:
Recruiting
Facility:
Name:
National Hospital Organization Shibukawa Medical Center
Address:
City:
Shibukawa
Zip:
377-0280
Country:
Japan
Status:
Recruiting
Facility:
Name:
Shizuoka Cancer Center
Address:
City:
Sunto-gun
Zip:
411-8777
Country:
Japan
Status:
Recruiting
Facility:
Name:
Yamagata University Hospital
Address:
City:
Yamagata
Zip:
990-2331
Country:
Japan
Status:
Recruiting
Facility:
Name:
Yamanashi Prefectural Central Hospital
Address:
City:
Yamanashi
Zip:
400-8506
Country:
Japan
Status:
Recruiting
Facility:
Name:
Dong-A University Hospital
Address:
City:
Busan
Zip:
49201
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Pusan National University Hospital
Address:
City:
Busan
Zip:
49241
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Kyungpook National University Hospital
Address:
City:
Daegu
Zip:
41944
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
National Cancer Center
Address:
City:
Goyang si
Zip:
10408
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Chonnam National University Hwasun Hospital
Address:
City:
Hwasun
Zip:
58128
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Gachon University Gil Medical Center
Address:
City:
Incheon
Zip:
21565
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Seoul National University Hospital
Address:
City:
Seoul
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Severance Hospital Yonsei University Health System
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Asan Medical Center
Address:
City:
Seoul
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Samsung Medical Center
Address:
City:
Seoul
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
The Catholic University of Korea Seoul St Mary s Hospital
Address:
City:
Seoul
Zip:
06591
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
VUMC Amsterdam
Address:
City:
Amsterdam
Zip:
1081 HV
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Gelre Ziekenhuis
Address:
City:
Apeldoorn
Zip:
7334 DZ
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Reinier de Graaf Gasthuis
Address:
City:
Delft
Zip:
2625 AD
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
St. Antonius Ziekenhuis Nieuwegein
Address:
City:
Nieuwegein
Zip:
3435 CM
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Zuyderland Medical Center
Address:
City:
Sittard-Geleen
Zip:
6162 BG
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Oslo University Hospital HF Ulleval sykehus
Address:
City:
Oslo
Zip:
0450
Country:
Norway
Status:
Recruiting
Facility:
Name:
St. Olavs Hospital
Address:
City:
Trondheim
Zip:
7030
Country:
Norway
Status:
Recruiting
Facility:
Name:
Wojewodzki Szpital Kliniczny w Bialej Podlaskiej
Address:
City:
Biala Podlaska
Zip:
21 500
Country:
Poland
Status:
Recruiting
Facility:
Name:
Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza
Address:
City:
Brzozow
Zip:
36-200
Country:
Poland
Status:
Recruiting
Facility:
Name:
Szpital Uniwersytecki nr 2 im. Jana Biziela w Bydgoszczy
Address:
City:
Bydgoszcz
Zip:
85-168
Country:
Poland
Status:
Recruiting
Facility:
Name:
Pratia Onkologia Katowice
Address:
City:
Katowice
Zip:
40 519
Country:
Poland
Status:
Recruiting
Facility:
Name:
Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach
Address:
City:
Kielce
Zip:
25-734
Country:
Poland
Status:
Recruiting
Facility:
Name:
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli
Address:
City:
Lublin
Zip:
20-090
Country:
Poland
Status:
Recruiting
Facility:
Name:
Szpital Uniwersytecki im Karola Marcinkowskiego w Zielonej Gorze
Address:
City:
Zielona Gora
Zip:
65 046
Country:
Poland
Status:
Recruiting
Facility:
Name:
Uls Braga - Hosp. Braga
Address:
City:
Braga
Zip:
4710-243
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Champalimaud Foundation Champalimaud Centre
Address:
City:
Lisbon
Zip:
1400-038
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Instituto Portugues de Oncologia
Address:
City:
Porto
Zip:
4200 072
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Uls Hosp Sao Joao
Address:
City:
Porto
Zip:
4200 319
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Germans Trias I Pujol
Address:
City:
Badalona
Zip:
08916
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. de La Santa Creu I Sant Pau
Address:
City:
Barcelona
Zip:
08025
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp Univ Vall D Hebron
Address:
City:
Barcelona
Zip:
08035
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Virgen de Las Nieves
Address:
City:
Granada
Zip:
18014
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. de Jerez de La Frontera
Address:
City:
Jerez de la Frontera
Zip:
11407
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. 12 de Octubre
Address:
City:
Madrid
Zip:
28041
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. La Paz
Address:
City:
Madrid
Zip:
28046
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp Univ Hm Sanchinarro
Address:
City:
Madrid
Zip:
28050
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Son Espases
Address:
City:
Palma de Mallorca
Zip:
07120
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Quiron Madrid Pozuelo
Address:
City:
Pozuelo de Alarcon
Zip:
28223
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp Clinico Univ de Salamanca
Address:
City:
Salamanca
Zip:
37007
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Mutua Terrassa
Address:
City:
Terrassa
Zip:
08221
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Clinico Univ. de Valencia
Address:
City:
Valencia
Zip:
46010
Country:
Spain
Status:
Recruiting
Facility:
Name:
Falu Lasarett
Address:
City:
Falun
Zip:
791 82
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Skanes universitetssjukhus
Address:
City:
Lund
Zip:
221 85
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Karolinska University Hospital Huddinge
Address:
City:
Stockholm
Zip:
141 86
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Universitetssjukhuset Orebro
Address:
City:
Örebro
Zip:
701 85
Country:
Sweden
Status:
Recruiting
Facility:
Name:
INSELSPITAL Universitatsspital Bern
Address:
City:
Bern
Zip:
3010
Country:
Switzerland
Status:
Recruiting
Facility:
Name:
Kantonsspital St Gallen
Address:
City:
St. Gallen
Zip:
9007
Country:
Switzerland
Status:
Recruiting
Facility:
Name:
Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital
Address:
City:
Ankara
Zip:
06200
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Ankara University Medical Faculty
Address:
City:
Ankara
Zip:
06590
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Liv Hospital Ankara
Address:
City:
Ankara
Zip:
06680
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Memorial Antalya Hospital
Address:
City:
Antalya
Zip:
07025
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Pamukkale University Medical Faculty
Address:
City:
Denizli
Zip:
20160
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Medipol University Hospital
Address:
City:
Istanbul
Zip:
34214
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Dokuz Eylul University Medical Faculty
Address:
City:
Izmir
Zip:
35340
Country:
Turkey
Status:
Completed
Facility:
Name:
Ondokuz Mayis University
Address:
City:
Samsun
Zip:
55280
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Blackpool Victoria Hospital
Address:
City:
Blackpool
Zip:
FY3 8NR
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
University Hospitals Bristol and Weston
Address:
City:
Bristol
Zip:
BS1 3NU
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Kent and Canterbury Hospital
Address:
City:
Canterbury
Zip:
CT1 3NG
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Western General Hospital
Address:
City:
Edinburgh
Zip:
EH4 2XU
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
University College London Hospitals
Address:
City:
London
Zip:
NW1 2BU
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Imperial College Healthcare
Address:
City:
London
Zip:
W2 1NY
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
New Cross Hospital
Address:
City:
Wolverhampton
Zip:
WV10 0QP
Country:
United Kingdom
Status:
Recruiting
Start date:
October 25, 2022
Completion date:
October 28, 2033
Lead sponsor:
Agency:
Janssen Research & Development, LLC
Agency class:
Industry
Source:
Janssen Research & Development, LLC
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05552222
