Trial Title:
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
NCT ID:
NCT05580562
Condition:
H3 K27M
Glioma
Conditions: Official terms:
Glioma
TIC10 compound
Conditions: Keywords:
H3 K27M
H3 K28M
H3 K27-altered
histone
H3F3A
HIST1H3B
HIST1H3C
H3.1
H3.3
DMG
thalamus
thalamic
midline
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
Triple (Participant, Care Provider, Investigator)
Intervention:
Intervention type:
Drug
Intervention name:
Dordaviprone (ONC201)
Description:
Participants ≥ 52.5 kg will receive 625 mg of ONC201 (5 × 125-mg capsules) dosing days;
participants < 52.5 kg will receive a dose (and corresponding number of capsules) scaled
by body weight and rounded to 125-mg increments.
Arm group label:
ONC201 Twice Weekly Group
Intervention type:
Drug
Intervention name:
Dordaviprone (ONC201) + Placebo
Description:
Participants ≥ 52.5 kg will receive 625 mg of ONC201 (5 × 125-mg capsules) or matching
placebo on dosing days; participants < 52.5 kg will receive a dose (and corresponding
number of capsules) scaled by body weight and rounded to 125-mg increments
Arm group label:
ONC201 Once Weekly Group
Intervention type:
Other
Intervention name:
Placebo
Description:
Participants will receive placebo (same number of capsules as the ONC201 dose) on dosing
days
Arm group label:
Placebo Group
Summary:
This is a randomized, double-blind, placebo-controlled, parallel-group, international,
Phase 3 study in patients with newly diagnosed H3 K27M-mutant diffuse glioma to assess
whether treatment with ONC201 following frontline radiotherapy will extend overall
survival and progression-free survival in this population. Eligible participants will
have histologically diagnosed H3 K27M-mutant diffuse glioma and have completed standard
frontline radiotherapy.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
1. Able to understand the study procedures and agree to participate in the study by
providing written informed consent (by participant or legally authorized
representative), and assent when applicable.
2. Body weight ≥ 10 kg at time of randomization.
3. Histologically diagnosed H3 K27M-mutant diffuse glioma (new diagnosis). Detection of
a missense K27M mutation in any histone H3-encoding gene detected by testing of
tumor tissue (immunohistochemistry [IHC] or next-generation sequencing [NGS] in a
Clinical Laboratory Improvement Amendments [CLIA]-certified or equivalent
laboratory). [Site to provide (as available): ≥ 10 unstained formalin-fixed
paraffin-embedded (FFPE) slides from tumor tissue.]
4. At least one, high-quality, contrast-enhanced MRI of the brain obtained prior to
starting radiotherapy for submission to sponsor's imaging vendor for central read.
For participants who had a surgical resection, this scan must be post-resection; for
participants who did not have a resection, this scan may be pre- or post-biopsy.
5. At least one, high-quality, contrast-enhanced MRI of the brain obtained 2 to 6 weeks
after completion of frontline radiotherapy. If unable to obtain contrast-enhanced
imaging due to lack of venous access after multiple attempts, a patient may still be
eligible after collection of a nonenhanced MRI of the brain. [Site to also provide
all available MRIs completed prior to initiating treatment with study intervention.]
6. Received frontline radiotherapy
1. Initiated radiotherapy within 12 weeks from the initial diagnosis of H3
K27M-mutant diffuse glioma.
2. Completed radiotherapy within 2 to 6 weeks prior to randomization
3. Completed standard fractionated radiotherapy (eg. 54 to 60 Gy in 28 to 33
fractions given over approximately 6 weeks or hypofractionated radiotherapy
(eg. 40 Gy in 15 fractions given over approximately 3 weeks).
7. Karnofsky Performance Status or Lansky Performance Status ≥ 70 at time of
randomization.
8. Stable or decreasing dose of corticosteroids and anti-seizure medications for 7 days
prior to randomization, if applicable. Stable steroid dose is defined as ≤ 2 mg/day
increase (based on dexamethasone dose or equivalent dose of an alternative steroid).
Exclusion Criteria:
1. Primary spinal tumor.
2. Diffuse intrinsic pontine glioma (DIPG), defined as tumors with a pontine epicenter
and diffuse involvement of the pons.
3. Evidence of leptomeningeal spread of disease or cerebrospinal fluid dissemination.
4. Any known concurrent malignancy.
5. New lesion(s) outside of the radiation field.
6. Received whole-brain radiotherapy.
7. Received proton therapy for glioma.
8. Use of any of the following treatments within the specified time periods prior to
randomization:
1. ONC201 or ONC206 at any time.
2. Systemic bevacizumab (includes biosimilars) at any time since the initial
diagnosis of H3 K27M-mutant diffuse glioma.
3. Temozolomide within past 3 weeks.
4. Tumor treating fields at any time.
5. DRD2 antagonist within past 2 weeks.
6. Any investigational therapy within past 4 weeks.
7. Strong CYP3A4 inhibitors within 3 days.
8. Strong CYP3A4 inducers (includes enzyme-inducing antiepileptic drugs) within 2
weeks.
9. Laboratory test results meeting any of the following parameters within 2 weeks prior
to randomization:
1. Absolute neutrophil count < 1.0 × 109/L or platelets < 75 × 109/L.
2. Total bilirubin > 1.5 × upper limit of normal (ULN) (participants with
Gilbert's syndrome may be included with total bilirubin > 1.5 × ULN if direct
bilirubin is ≤ 1.5 × ULN).
3. Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) > 2.5 × ULN.
4. Creatinine clearance ≤ 60 mL/min as calculated by the Cockcroft Gault equation
(or estimated glomerular filtration rate < 60 mL/min/1.73 m2).
10. QTc > 480 msec (based on mean from triplicate electrocardiograms) during screening.
11. Known hypersensitivity to any excipients used in the study intervention formulation.
12. Pregnant, breastfeeding, or planning to become pregnant while receiving study
intervention or within 3 months after the last dose. Participants of childbearing
potential must have a negative serum pregnancy test within 72 hours prior to
receiving the first dose of study intervention.
13. Uncontrolled intercurrent illness including, but not limited to, ongoing or active
infection requiring systemic therapy or psychiatric illness/social situations that
would limit compliance with study requirements.
14. Any other condition (eg, medical, psychiatric, or social) that, in the opinion of
the investigator, may interfere with participant safety or the ability to complete
the study according to the protocol.
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Barrow Neurological Institute
Address:
City:
Phoenix
Zip:
085013
Country:
United States
Status:
Recruiting
Contact:
Last name:
Robert Yoo, DO
Phone:
602-406-8605
Email:
research@ivybraintumorcenter.org
Investigator:
Last name:
Robert Yoo, DO
Email:
Principal Investigator
Facility:
Name:
Banner MD Anderson Cancer Center
Address:
City:
Phoenix
Zip:
85006
Country:
United States
Status:
Recruiting
Contact:
Last name:
Na Tosha Gatson
Investigator:
Last name:
Na Tosha Gatson
Email:
Principal Investigator
Facility:
Name:
Phoenix Childrens Hospital
Address:
City:
Phoenix
Zip:
85016
Country:
United States
Status:
Recruiting
Contact:
Last name:
Lindsey Hoffmann, DO
Email:
lhoffman1@phoenixchildrens.com
Investigator:
Last name:
Lindsey Hoffmann, DO
Email:
Principal Investigator
Facility:
Name:
Mayo Clinic Arizona
Address:
City:
Phoenix
Zip:
85054
Country:
United States
Status:
Recruiting
Contact:
Last name:
Maciej Mrugala, MD
Email:
mrugala.maciej@mayo.edu
Investigator:
Last name:
Maciej Mrugala, MD
Email:
Principal Investigator
Facility:
Name:
University of California Irvine
Address:
City:
Costa Mesa
Zip:
92628
Country:
United States
Status:
Recruiting
Contact:
Last name:
Xiao-Tang Kong, MD, PhD
Email:
xkong@hs.uci.edu
Investigator:
Last name:
Xiao-Tang Kong, MD, PhD
Email:
Principal Investigator
Facility:
Name:
UC San Diego Moores Cancer Center
Address:
City:
La Jolla
Zip:
92093
Country:
United States
Status:
Recruiting
Contact:
Last name:
Jessica Schulte, MD
Email:
jdschulte@health.ucsd.edu
Investigator:
Last name:
Jessica Schulte, MD
Email:
Principal Investigator
Facility:
Name:
Kaiser Permanente Los Angeles Medical Center
Address:
City:
Los Angeles
Zip:
90027
Country:
United States
Status:
Recruiting
Contact:
Last name:
Richard Green, MD
Email:
richard.m.green@kp.org
Investigator:
Last name:
Richard Green, MD
Email:
Principal Investigator
Facility:
Name:
UCLA University of California Los Angeles
Address:
City:
Los Angeles
Zip:
90095
Country:
United States
Status:
Recruiting
Contact:
Last name:
Phioanh Nghiemphu, MD
Email:
PNghiemphu@mednet.ucla.edu
Investigator:
Last name:
Phioanh Nghiemphu, MD
Email:
Principal Investigator
Facility:
Name:
Children's Hospital of Orange County
Address:
City:
Orange
Zip:
92868
Country:
United States
Status:
Recruiting
Contact:
Last name:
Mariko Sato, MD, PhD
Email:
Mariko.Sato@choc.org
Investigator:
Last name:
Mariko Sato, MD, PhD
Email:
Principal Investigator
Facility:
Name:
UCSF Benioff Children's Hospital
Address:
City:
San Francisco
Zip:
94143
Country:
United States
Status:
Recruiting
Contact:
Last name:
Nicholas Butowski, MD
Email:
nicholas.butowski@ucsf.edu
Investigator:
Last name:
Nicholas Butowski, MD
Email:
Principal Investigator
Facility:
Name:
University of California San Francisco
Address:
City:
San Francisco
Zip:
94143
Country:
United States
Status:
Recruiting
Contact:
Last name:
Nicholas Butowski, MD
Email:
nicholas.butowski@ucsf.edu
Investigator:
Last name:
Nicholas Butowski, MD
Email:
Principal Investigator
Facility:
Name:
Providence Saint John's Cancer Institute
Address:
City:
Santa Monica
Zip:
90404
Country:
United States
Status:
Recruiting
Contact:
Last name:
Akanksha Sharma, MD
Email:
neuro.research@providence.org
Investigator:
Last name:
Akanksha Sharma, MD
Email:
Principal Investigator
Facility:
Name:
Stanford Cancer Center
Address:
City:
Stanford
Zip:
94350
Country:
United States
Status:
Recruiting
Contact:
Last name:
Kate Therkelsen, MD
Email:
ktherk@stanford.edu
Investigator:
Last name:
Kate Therkelsen, MD
Email:
Principal Investigator
Facility:
Name:
Yale University
Address:
City:
Fairfield
Zip:
06824
Country:
United States
Status:
Recruiting
Contact:
Last name:
Nicholas Blondin, MD
Email:
nblondin@anscneuro.com
Investigator:
Last name:
Nicholas Blondin, MD
Email:
Principal Investigator
Facility:
Name:
MedStar Georgetown University Hospital
Address:
City:
Washington
Zip:
20007
Country:
United States
Status:
Recruiting
Contact:
Last name:
Edina Komlodi-Pasztor, MD, PhD
Email:
Edina.Komlodi-Pasztor@medstar.net
Investigator:
Last name:
Edina Komlodi-Pasztor, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Mayo Clinic Jacksonville
Address:
City:
Jacksonville
Zip:
32224
Country:
United States
Status:
Recruiting
Contact:
Last name:
Kurt Jaeckle, MD
Email:
jaeckle.kurt@mayo.edu
Investigator:
Last name:
Kurt Jaeckle, MD
Email:
Principal Investigator
Facility:
Name:
Miami Cancer Institute
Address:
City:
Miami
Zip:
33176
Country:
United States
Status:
Recruiting
Contact:
Last name:
Yazmin Odia, MD
Phone:
786-596-2000
Email:
YazminO@BaptistHealth.net
Contact backup:
Last name:
Paul R Ferguson
Email:
Paul.Ferguson@baptisthealth.net
Investigator:
Last name:
Yazmin Odia, MD
Email:
Principal Investigator
Facility:
Name:
St Joseph's Children's Hospital of Tampa
Address:
City:
Tampa
Zip:
33607
Country:
United States
Status:
Recruiting
Contact:
Last name:
Trisha Larkin, MD
Email:
trisha.larkin@baycare.org
Investigator:
Last name:
Trisha Larkin, MD
Email:
Principal Investigator
Facility:
Name:
Moffitt Cancer Center
Address:
City:
Tampa
Zip:
33612
Country:
United States
Status:
Recruiting
Contact:
Last name:
Michael Vogelbaum, MD
Email:
michael.vogelbaum@moffitt.org
Investigator:
Last name:
Michael Vogelbaum, MD
Email:
Principal Investigator
Facility:
Name:
Children's Healthcare of Atlanta
Address:
City:
Atlanta
Zip:
30342
Country:
United States
Status:
Recruiting
Contact:
Last name:
Tobey MacDonald, MD
Email:
tobey.macdonald@emory.edu
Investigator:
Last name:
Tobey MacDonald, MD
Email:
Principal Investigator
Facility:
Name:
Kapi'olani Medical Center for Women and Children
Address:
City:
Honolulu
Zip:
96826
Country:
United States
Status:
Recruiting
Contact:
Last name:
Kelley Hutchins, DO, MPH
Email:
kelley.hutchins@hphmg.org
Investigator:
Last name:
Kelley Hutchins, DO, MPH
Email:
Principal Investigator
Facility:
Name:
Feinberg School of Medicine Northwestern University
Address:
City:
Chicago
Zip:
60611
Country:
United States
Status:
Recruiting
Contact:
Last name:
Karan Dixit, MD
Email:
karan.dixit@nm.org
Investigator:
Last name:
Karan Dixit, MD
Email:
Principal Investigator
Facility:
Name:
Indiana University School of Medicine - Indianapolis
Address:
City:
Indianapolis
Zip:
46202
Country:
United States
Status:
Recruiting
Contact:
Last name:
Daniel Runco, MD
Email:
drunco@iupui.edu
Investigator:
Last name:
Daniel Runco, MD
Email:
Principal Investigator
Facility:
Name:
University of Iowa Hospitals & Clinics
Address:
City:
Iowa City
Zip:
52242
Country:
United States
Status:
Recruiting
Contact:
Last name:
David Dickens, MD
Email:
david-dickens@uiowa.edu
Investigator:
Last name:
David Dickens, MD
Email:
Principal Investigator
Facility:
Name:
Norton Healthcare
Address:
City:
Louisville
Zip:
40241
Country:
United States
Status:
Recruiting
Contact:
Last name:
Kaylyn Sinicrope, MD
Email:
Kaylyn.Sinicrope@nortonhealthcare.org
Investigator:
Last name:
Kaylyn Sinicrope, MD
Email:
Principal Investigator
Facility:
Name:
Ochsner Medical Center - New Orleans
Address:
City:
New Orleans
Zip:
70121
Country:
United States
Status:
Recruiting
Contact:
Last name:
Caroline Goldin, MD
Email:
caroline.goldin@ochsner.org
Investigator:
Last name:
Caroline Goldin, MD
Email:
Principal Investigator
Facility:
Name:
University of Maryland School of Medicine
Address:
City:
Baltimore
Zip:
21201
Country:
United States
Status:
Recruiting
Contact:
Last name:
Lily Pham, MD
Email:
lpham@som.umaryland.edu
Investigator:
Last name:
Lily Pham, MD
Email:
Principal Investigator
Facility:
Name:
Massachusetts General Hospital Cancer Center
Address:
City:
Boston
Zip:
02114
Country:
United States
Status:
Recruiting
Contact:
Last name:
Isabel Arrillaga-Romany, MD
Email:
iarrillaga@mgh.harvard.edu
Investigator:
Last name:
Isabel Arrillaga-Romany, MD
Email:
Principal Investigator
Facility:
Name:
Dana Farber Cancer Institute
Address:
City:
Boston
Zip:
02215
Country:
United States
Status:
Recruiting
Contact:
Last name:
Patrick Wen, MD
Email:
pwen@partners.org
Investigator:
Last name:
Patrick Wen, MD
Email:
Principal Investigator
Facility:
Name:
University of Michigan Hospital
Address:
City:
Ann Arbor
Zip:
48109
Country:
United States
Status:
Recruiting
Contact:
Last name:
Carl Koschmann, MD
Email:
ckoschma@med.umich.edu
Investigator:
Last name:
Carl Koschmann, MD
Email:
Principal Investigator
Facility:
Name:
University of Minnesota
Address:
City:
Minneapolis
Zip:
55455
Country:
United States
Status:
Recruiting
Contact:
Last name:
Elizabeth Neil, MD
Email:
neile@umn.edu
Investigator:
Last name:
Elizabeth Neil, MD
Email:
Principal Investigator
Facility:
Name:
Mayo Clinic - Cancer Center - Rochester
Address:
City:
Rochester
Zip:
55905
Country:
United States
Status:
Recruiting
Contact:
Last name:
Michael Ruff, MD
Email:
Ruff.Michael@mayo.edu
Investigator:
Last name:
Michael Ruff, MD
Email:
Principal Investigator
Facility:
Name:
Washington University School of Medicine
Address:
City:
Saint Louis
Zip:
63110
Country:
United States
Status:
Recruiting
Contact:
Last name:
Andrew Cluster, MD
Email:
acluster@wustl.edu
Investigator:
Last name:
Andrew Cluster, MD
Email:
Principal Investigator
Facility:
Name:
Benefis Hospital Sletten Cancer Institute
Address:
City:
Great Falls
Zip:
59405
Country:
United States
Status:
Withdrawn
Facility:
Name:
University of Nebraska Medical Center
Address:
City:
Omaha
Zip:
68114
Country:
United States
Status:
Recruiting
Contact:
Last name:
Chittalsinh Raulji, MD
Email:
craulji@childrensomaha.org
Investigator:
Last name:
Chittalsinh Raulji, MD
Email:
Principal Investigator
Facility:
Name:
Jersey Shore University Medical Center
Address:
City:
Neptune
Zip:
07753
Country:
United States
Status:
Recruiting
Contact:
Last name:
Shama Farooq, MD
Email:
shama.farooq@hmhn.org
Investigator:
Last name:
Shama Farooq, MD
Email:
Principal Investigator
Facility:
Name:
Overlook Medical Center
Address:
City:
Summit
Zip:
07901
Country:
United States
Status:
Recruiting
Contact:
Last name:
Robert Aiken
Email:
Robert.Aiken@atlantichealth.org
Investigator:
Last name:
Robert Aiken
Email:
Principal Investigator
Facility:
Name:
Albany Medical Center
Address:
City:
Albany
Zip:
12208
Country:
United States
Status:
Recruiting
Contact:
Last name:
Lauren Weintraub, MD
Email:
weintrl@amc.edu
Investigator:
Last name:
Lauren Weintraub, MD
Email:
Principal Investigator
Facility:
Name:
Children's Hospital at Montefiore Medical Center
Address:
City:
New York
Zip:
10029
Country:
United States
Status:
Recruiting
Contact:
Last name:
Adilia Hormigo, MD, PhD
Email:
adilia.hormigo@einsteinmed.edu
Investigator:
Last name:
Adilia Hormigo, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Montefiore Medical Park
Address:
City:
New York
Zip:
10029
Country:
United States
Status:
Recruiting
Contact:
Last name:
Adilia Hormigo, MD, PhD
Email:
adilia.hormigo@einsteinmed.edu
Investigator:
Last name:
Adilia Hormigo, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Laura & Isaac Perlmutter Cancer Center - NYU ACC
Address:
City:
New York
Zip:
10032-3726
Country:
United States
Status:
Recruiting
Contact:
Last name:
Marissa Barbaro, MD
Email:
Marissa.Barbaro@nyulangone.org
Investigator:
Last name:
Marissa Barbaro, MD
Email:
Principal Investigator
Facility:
Name:
Columbia University Medical Center
Address:
City:
New York
Zip:
10032
Country:
United States
Status:
Recruiting
Contact:
Last name:
Aya Haggiagi
Email:
amh2237@cumc.columbia.edu
Investigator:
Last name:
Aya Haggiagi
Email:
Principal Investigator
Facility:
Name:
Columbia University Medical Center
Address:
City:
New York
Zip:
10032
Country:
United States
Status:
Recruiting
Contact:
Last name:
Luca Szalontay, MD
Email:
ls3399@cumc.columbia.edu
Investigator:
Last name:
Luca Szalontay, MD
Email:
Principal Investigator
Facility:
Name:
Lenox Hill Hospital
Address:
City:
New York
Zip:
10075
Country:
United States
Status:
Recruiting
Contact:
Last name:
John Boockvar, MD
Email:
jboockvar@nshs.edu
Investigator:
Last name:
John Boockvar, MD
Email:
Principal Investigator
Facility:
Name:
University of Rochester Medical Center
Address:
City:
Rochester
Zip:
14642
Country:
United States
Status:
Recruiting
Contact:
Last name:
David Korones, MD
Email:
david_korones@urmc.rochester.edu
Investigator:
Last name:
David Korones, MD
Email:
Principal Investigator
Facility:
Name:
Levine Cancer Institute/ Atrium Health
Address:
City:
Charlotte
Zip:
28204
Country:
United States
Status:
Recruiting
Contact:
Last name:
Ashley Sumrall, MD
Email:
ashley.sumrall@atriumhealth.org
Investigator:
Last name:
Ashley Sumrall, MD
Email:
Principal Investigator
Facility:
Name:
Duke Cancer Institute
Address:
City:
Durham
Zip:
27710
Country:
United States
Status:
Recruiting
Contact:
Last name:
Margaret Johnson, MD, MPH
Email:
margaret.o.johnson@duke.edu
Investigator:
Last name:
Margaret Johnson, MD, MPH
Email:
Principal Investigator
Facility:
Name:
Cincinnati Children's Hospital Medical Center
Address:
City:
Cincinnati
Zip:
45229
Country:
United States
Status:
Recruiting
Contact:
Last name:
Peter de Blank, MD
Email:
cancer@cchmc.org
Investigator:
Last name:
Peter de Blank, MD
Email:
Principal Investigator
Facility:
Name:
Cleveland Clinic
Address:
City:
Cleveland
Zip:
44195
Country:
United States
Status:
Recruiting
Contact:
Last name:
Christine Cordova, MD
Email:
cordovc@ccf.org
Investigator:
Last name:
Christine Cordova, MD
Email:
Principal Investigator
Facility:
Name:
Ohio Statue University
Address:
City:
Columbus
Zip:
43210
Country:
United States
Status:
Recruiting
Contact:
Last name:
Shirley Ong, MD
Email:
Shirley.Ong@osumc.edu
Investigator:
Last name:
Shirley Ong, MD
Email:
Principal Investigator
Facility:
Name:
University of Oklahoma Peggy and Charles Stephenson Cancer Center
Address:
City:
Oklahoma City
Zip:
73104
Country:
United States
Status:
Recruiting
Contact:
Last name:
Maya Hrachova, DO
Email:
maya-hrachova@ouhsc.edu
Investigator:
Last name:
Maya Hrachova, DO
Email:
Principal Investigator
Facility:
Name:
Providence Health and Services St. Vincent Medical Center
Address:
City:
Portland
Zip:
97239
Country:
United States
Status:
Recruiting
Contact:
Last name:
Prakash Ambady
Email:
Prakash.Ambady@providence.org
Investigator:
Last name:
Prakash Ambady, MB, MD
Email:
Principal Investigator
Facility:
Name:
University of Pennsylvania
Address:
City:
Philadelphia
Zip:
19104
Country:
United States
Status:
Recruiting
Contact:
Last name:
Stephen Bagley, MD
Email:
sbagley@pennmedicine.upenn.edu
Investigator:
Last name:
Stephen Bagley, MD
Email:
Principal Investigator
Facility:
Name:
Thomas Jefferson University
Address:
City:
Philadelphia
Zip:
19107
Country:
United States
Status:
Recruiting
Contact:
Last name:
Nina Martinez, MD
Email:
nina.martinez@jefferson.edu
Investigator:
Last name:
Nina Martinez, MD
Email:
Principal Investigator
Facility:
Name:
UPMC Hillman Cancer Center
Address:
City:
Pittsburgh
Zip:
15232
Country:
United States
Status:
Recruiting
Contact:
Last name:
Frank Lieberman, MD
Email:
liebermanf@upmc.edu
Investigator:
Last name:
Frank Lieberman, MD
Email:
Principal Investigator
Facility:
Name:
Dell Children's Medical Center of Central Texas
Address:
City:
Austin
Zip:
78723
Country:
United States
Status:
Recruiting
Contact:
Last name:
Sage Green, DO, MD
Email:
sage.green@ascension.org
Investigator:
Last name:
Sage Green, DO, MD
Email:
Principal Investigator
Facility:
Name:
Neuro-Oncology Associates
Address:
City:
Dallas
Zip:
75246
Country:
United States
Status:
Recruiting
Contact:
Last name:
Karen Fink, MD, PhD
Email:
karenfin@baylorhealth.edu
Investigator:
Last name:
Karen Fink, MD, PhD
Email:
Principal Investigator
Facility:
Name:
University of Texas Southwestern Medical Center
Address:
City:
Dallas
Zip:
75390
Country:
United States
Status:
Recruiting
Contact:
Last name:
Daniel Bowers, MD
Email:
daniel.bowers@utsouthwestern.edu
Investigator:
Last name:
Daniel Bowers, MD
Email:
Principal Investigator
Facility:
Name:
University of Texas MD Anderson Cancer Center
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Contact:
Last name:
Evguenia Gachimova (Adults
Phone:
832-266-3519
Contact backup:
Last name:
Wafik Zaky (Pediatrics)
Phone:
713-745-1862
Investigator:
Last name:
Nazanin Majd (Adults)
Email:
Principal Investigator
Investigator:
Last name:
Wafik Zaky (Pediatrics)
Email:
Sub-Investigator
Facility:
Name:
UT Health Science Center Houston Department of Neurosurgery
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Contact:
Last name:
Jay-Jiguang Zhu, MD
Email:
Jay.Jiguang.Zhu@uth.tmc.edu
Investigator:
Last name:
Jay-Jiguang Zhu, MD
Email:
Principal Investigator
Facility:
Name:
University of Texas - San Antonio - Health Science Center
Address:
City:
San Antonio
Zip:
78229
Country:
United States
Status:
Recruiting
Contact:
Last name:
Andrew Brenner, MD
Email:
brennera@uthscsa.edu
Investigator:
Last name:
Andrew Brenner, MD
Email:
Principal Investigator
Facility:
Name:
University of Utah - Huntsman Cancer Institute
Address:
City:
Salt Lake City
Zip:
84112
Country:
United States
Status:
Recruiting
Contact:
Last name:
Rachel Kingsford
Phone:
801-585-0115
Email:
rachel.kingsford@hci.utah.edu
Contact backup:
Last name:
Yuri Kida
Phone:
801-646-4397
Email:
yuri.kida@hci.utah.edu
Investigator:
Last name:
Joe Mendez, MD
Email:
Principal Investigator
Facility:
Name:
Inova Schar Cancer Institute
Address:
City:
Fairfax
Zip:
22031
Country:
United States
Status:
Recruiting
Contact:
Last name:
Adam Cohen, MD
Email:
adam.cohen@inova.org
Investigator:
Last name:
Adam Cohen, MD
Email:
Principal Investigator
Facility:
Name:
Children's Hospital of The King's Daughter
Address:
City:
Norfolk
Zip:
23507
Country:
United States
Status:
Recruiting
Contact:
Last name:
Melissa Mark, MD
Email:
melissa.mark@chkd.org
Investigator:
Last name:
Melissa Mark, MD
Email:
Principal Investigator
Facility:
Name:
University of Washington
Address:
City:
Seattle
Zip:
98195
Country:
United States
Status:
Recruiting
Contact:
Last name:
Tresa McGranahan, MD
Email:
tresa@uw.edu
Investigator:
Last name:
Tresa McGranahan, MD
Email:
Principal Investigator
Facility:
Name:
University Of Wisconsin - Madison
Address:
City:
Madison
Zip:
53792
Country:
United States
Status:
Recruiting
Contact:
Last name:
Ankush Bhatia, MD
Email:
bhatia@neurology.wisc.edu
Investigator:
Last name:
Ankush Bhatia, MD
Email:
Principal Investigator
Facility:
Name:
Sydney Children's Hospital
Address:
City:
Randwick
Zip:
2031
Country:
Australia
Status:
Recruiting
Contact:
Last name:
David Ziegler, BS, MB, MD
Email:
d.ziegler@unsw.edu.au
Investigator:
Last name:
David Ziegler, BS, MB, MD
Email:
Principal Investigator
Facility:
Name:
Royal North Shore Hospital
Address:
City:
Sydney
Zip:
2065
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Helen Wheeler, MD
Email:
helen.wheeler@health.nsw.gov.au
Investigator:
Last name:
Helen Wheeler, MD
Email:
Principal Investigator
Facility:
Name:
Royal Brisbane and Women's Hospital
Address:
City:
Herston
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Zarnie Lwin, MD
Email:
zarnie.lwin@health.qld.gov.au
Investigator:
Last name:
Zarnie Lwin, MD
Email:
Principal Investigator
Facility:
Name:
Royal Hobart Hospital
Address:
City:
Hobart
Zip:
7000
Country:
Australia
Status:
Recruiting
Contact:
Last name:
John Heath
Email:
john.heath@ths.tas.gov.au
Investigator:
Last name:
John Heath
Email:
Principal Investigator
Facility:
Name:
Olivia Newton-John Cancer Research Institute (ONJCRI)
Address:
City:
Heidelberg
Zip:
3084
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Lawrence Cher
Email:
lawrence.cher@austin.org.au
Investigator:
Last name:
Lawrence Cher
Email:
Principal Investigator
Facility:
Name:
Perth Children's Hospital
Address:
City:
Nedlands
Zip:
6009
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Santosh Valvi
Email:
Santosh.Valvi@health.wa.gov.au
Investigator:
Last name:
Santosh Valvi
Email:
Principal Investigator
Facility:
Name:
Medical University of Vienna - Adults
Address:
City:
Vienna
Zip:
01090
Country:
Austria
Status:
Recruiting
Contact:
Last name:
Anna Bergmeister-Berghoff, MD
Email:
anna.berghoff@meduniwien.ac.at
Investigator:
Last name:
Anna Bergmeister-Berghoff, MD
Email:
Principal Investigator
Facility:
Name:
Medical University of Vienna - Pediatrics
Address:
City:
Vienna
Country:
Austria
Status:
Recruiting
Contact:
Last name:
Johannes Gojo
Email:
johannes.gojo@meduniwien.ac.at
Investigator:
Last name:
Johannes Gojo
Email:
Principal Investigator
Facility:
Name:
Tom Baker Cancer Cetre
Address:
City:
Calgary
Zip:
T2N 2T9
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Paula De Robles, MD
Email:
paula.derobles@ahs.ca
Investigator:
Last name:
Paula De Robles, MD
Email:
Principal Investigator
Facility:
Name:
BC Cancer - The Vancouver Center
Address:
City:
Vancouver
Zip:
V5Z 4E6
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Rebecca Harrison, MD
Phone:
+1-604-877-6000
Investigator:
Last name:
Rebecca Harrison, MD
Email:
Principal Investigator
Facility:
Name:
Children's & Women's Health Care of BC
Address:
City:
Vancouver
Zip:
V6H 0B3
Country:
Canada
Status:
Recruiting
Contact:
Last name:
George Michaiel
Email:
george.michaiel@cw.bc.ca
Investigator:
Last name:
George Michaiel
Email:
Principal Investigator
Facility:
Name:
London Health Sciences Centre
Address:
City:
London
Zip:
N6A 5W9
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Seth Climans, MD
Email:
Seth.Climans@lhsc.on.ca
Investigator:
Last name:
Seth Climans, MD
Email:
Principal Investigator
Facility:
Name:
Childrens Hospital of Eastern Ontario
Address:
City:
Ottawa
Zip:
K1H 8L1
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Donna Johnston, MD
Email:
djohnston@cheo.on.ca
Investigator:
Last name:
Donna Johnston, MD
Email:
Principal Investigator
Facility:
Name:
Sunnybrook Health Sciences Centre
Address:
City:
Toronto
Zip:
M4N 3M5
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Mary Lim-Fat, MD
Email:
maryjane.limfat@sunnybrook.ca
Investigator:
Last name:
Mary Lim-Fat, MD
Email:
Principal Investigator
Facility:
Name:
Princess Margaret Hospital
Address:
City:
Toronto
Zip:
M5G 1X8
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Julie Bennett, MD
Email:
julie.bennett@sickkids.ca
Investigator:
Last name:
Julie Bennett, MD
Email:
Principal Investigator
Facility:
Name:
Hopital Notre Dame, Lachapelle
Address:
City:
Montréal
Zip:
H2X 3E4
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Sarah Lapointe
Email:
sarah.lapointe.med@ssss.gouv.qc.ca
Investigator:
Last name:
Sarah Lapointe
Email:
Principal Investigator
Facility:
Name:
Copenhagen University Hospital
Address:
City:
Copenhagen
Zip:
2100
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Søren Møller, MD
Email:
soeren.moeller.01@regionh.dk
Investigator:
Last name:
Søren Møller, MD
Email:
Principal Investigator
Facility:
Name:
Aalborg Universitetshospital
Address:
City:
Aalborg
Zip:
9000
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Charlotte Aaquist Haslund, MD
Email:
cah@rn.dk
Investigator:
Last name:
Charlotte Aaquist Haslund, MD
Email:
Principal Investigator
Facility:
Name:
F345 H.C. Andersen's Children's Hospital
Address:
City:
Odense
Zip:
5000
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Michael Callesen
Email:
michael.callesen@rsyd.dk
Investigator:
Last name:
Michael Callesen
Email:
Principal Investigator
Facility:
Name:
Odense Universitetshospital
Address:
City:
Odense
Zip:
5000
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Rikke Dahlrot, MD
Email:
rikke.dahlrot@rsyd.dk
Investigator:
Last name:
Rikke Dahlrot, MD
Email:
Principal Investigator
Facility:
Name:
University Clinic Heidelberg
Address:
City:
Heidelberg
Zip:
69120
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Cornelis van Tilburg, MD, PhD
Email:
cornelis.vantilburg@kitz-heidelberg.de
Investigator:
Last name:
Cornelis van Tilburg, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Universitätsklinikum Heidelberg
Address:
City:
Heidelberg
Zip:
69120
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Antje Wick, MD
Email:
antje.wick@med.uni-heidelberg.de
Investigator:
Last name:
Antje Wick, MD
Email:
Principal Investigator
Facility:
Name:
Universitätsklinikum Augsburg
Address:
City:
Augsburg
Zip:
86156
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Michael Frühwald, MD
Email:
michael.fruehwald@klinikum-augsburg.de
Investigator:
Last name:
Michael Frühwald, MD
Email:
Principal Investigator
Facility:
Name:
University Clinic Regensburg
Address:
City:
Regensburg
Zip:
93053
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Peter Hau, MD
Email:
peter.hau@ukr.de
Investigator:
Last name:
Peter Hau, MD
Email:
Principal Investigator
Facility:
Name:
Klinikum der Johann-Wolfgang Goethe-Universitat
Address:
City:
Frankfurt am Main
Zip:
60528
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Michael Ronellenfitsch, MD
Email:
michael.ronellenfitsch@kgu.de
Investigator:
Last name:
Michael Ronellenfitsch, MD
Email:
Principal Investigator
Facility:
Name:
Universitätsklinikum Bonn
Address:
City:
Bonn
Zip:
53127
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Ulrich Herrlinger, MD
Email:
ulrich.herrlinger@ukb.uni-bonn.de
Investigator:
Last name:
Ulrich Herrlinger, MD
Email:
Principal Investigator
Facility:
Name:
Universitätsklinikum Essen
Address:
City:
Essen
Zip:
45147
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Martin Glas, MD
Email:
martin.glas@uk-essen.de
Investigator:
Last name:
Martin Glas, MD
Email:
Principal Investigator
Facility:
Name:
Uniklinik Köln
Address:
City:
Köln
Zip:
50937
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Roland Goldbrunner, MD, PhD
Email:
roland.goldbrunner@uk-koeln.de
Investigator:
Last name:
Roland Goldbrunner, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Vivantes Klinikum Neukölln
Address:
City:
Berlin
Zip:
12351
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Andreas Jödicke, MD
Email:
andreas.joedicke@vivantes.de
Investigator:
Last name:
Andreas Jödicke, MD
Email:
Principal Investigator
Facility:
Name:
Klinikum Mannheim Universitätsklinikum gGmbH
Address:
City:
Manheim
Zip:
68167
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Katharina Sahm, MD
Email:
katharina.sahm@umm.de
Investigator:
Last name:
Katharina Sahm, MD
Email:
Principal Investigator
Facility:
Name:
Universitätsklinikum Tübingen
Address:
City:
Tübingen
Zip:
72076
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Sylvia Kurz, MD
Email:
sylvia.kurz@med.uni-tuebingen.de
Investigator:
Last name:
Sylvia Kurz, MD
Email:
Principal Investigator
Facility:
Name:
Queen Mary Hospital
Address:
City:
Hong Kong
Zip:
999077
Country:
Hong Kong
Status:
Recruiting
Contact:
Last name:
Aya El Helali, MD
Email:
ahelali@hku.hk
Investigator:
Last name:
Aya El Helali, MD
Email:
Principal Investigator
Facility:
Name:
Sheba Medical Center
Address:
City:
Ramat Gan
Zip:
5262100
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Michal Yalon, MD, PhD
Email:
michal.yalon@sheba.health.gov.il
Investigator:
Last name:
Michal Yalon, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Soroka University Medical Centre
Address:
City:
Be'er Sheva
Zip:
50937
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Abed El Salem Abu Quider, MD
Email:
abeda@clalit.org.il
Investigator:
Last name:
Abed El Salem Abu Quider, MD
Email:
Principal Investigator
Facility:
Name:
Rambam Medical Center
Address:
City:
Haifa
Zip:
31096
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Liat Oren
Email:
li_oren@rmc.gov.il
Investigator:
Last name:
Liat Oren
Email:
Principal Investigator
Facility:
Name:
Hadassah Ein Kerem Medical Center
Address:
City:
Jerusalem
Zip:
91120
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Alexander Lossos, MD
Email:
alos@hadassah.org.il
Investigator:
Last name:
Alexander Lossos, MD
Email:
Principal Investigator
Facility:
Name:
Schneider Children's Medical Center of Israel
Address:
City:
Petah Tikvah
Zip:
4920235
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Helen Toledano, MD
Email:
Helent@clalit.org.il
Investigator:
Last name:
Helen Toledano, MD
Email:
Principal Investigator
Facility:
Name:
Rabin Medical Center
Address:
City:
Petah Tikva
Zip:
49372
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Shlomit Yust-Katz, MD
Email:
shlomit2@clalit.org.il
Investigator:
Last name:
Shlomit Yust-Katz, MD
Email:
Principal Investigator
Facility:
Name:
Tel Aviv Sourasky Medical Center
Address:
City:
Tel Aviv
Zip:
64239
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Deborah Blumenthal, MD
Email:
Dvorab@tlvmc.gov.il
Investigator:
Last name:
Deborah Blumenthal, MD
Email:
Principal Investigator
Facility:
Name:
Ospedale Bellaria
Address:
City:
Bologna
Zip:
40139
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Enrico Franceschi, MD
Email:
e.franceschi@ausl.bo.it
Investigator:
Last name:
Enrico Franceschi, MD
Email:
Principal Investigator
Facility:
Name:
Istituto Nazionale Tumori Regina Elena
Address:
City:
Roma
Zip:
00144
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Andrea Pace, MD, PhD
Email:
andrea.pace@ifo.it
Investigator:
Last name:
Andrea Pace, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Ospedale San Raffaele S.r.l.
Address:
City:
Milano
Zip:
20132
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Gaetano Finocchiaro, MD
Email:
gaetano.finocchiaro@hsr.it
Investigator:
Last name:
Gaetano Finocchiaro, MD
Email:
Principal Investigator
Facility:
Name:
Fondazione IRCCS Di Rilievo Nazionale Istituto Nazionale Neurologico Carlo Besta
Address:
City:
Milano
Zip:
20133
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Paola Gaviani, MD
Email:
paola.gaviani@istituto-besta.it
Investigator:
Last name:
Paola Gaviani, MD
Email:
Principal Investigator
Facility:
Name:
Istituto Clinico Humanitas
Address:
City:
Rozzano
Zip:
20089
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Matteo Simonelli, MD
Email:
matteo.simonelli@humanitas.it
Investigator:
Last name:
Matteo Simonelli, MD
Email:
Principal Investigator
Facility:
Name:
Azienda Ospedaliera Città della Salute e della Scienza di Torino
Address:
City:
Torino
Zip:
10126
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Alessia Pellerino, MD
Email:
alessia.pellerino@unito.it
Investigator:
Last name:
Alessia Pellerino, MD
Email:
Principal Investigator
Facility:
Name:
Istituto Oncologico Veneto
Address:
City:
Padova
Zip:
35128
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Giuseppe Lombardi, MD, PhD
Email:
giuseppe.lombardi@iov.veneto.it
Investigator:
Last name:
Giuseppe Lombardi, MD, PhD
Email:
Principal Investigator
Facility:
Name:
National Cancer Center Hospital
Address:
City:
Chuo City
Zip:
104-0045
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Yoshitaka Narita, MD
Email:
yonarita@ncc.go.jp
Investigator:
Last name:
Yoshitaka Narita, MD
Email:
Principal Investigator
Facility:
Name:
Osaka City General Hospital
Address:
City:
Osaka
Zip:
534-0021
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Keiko Okada
Email:
keiko-okada@med.osakacity-hp.or.jp
Investigator:
Last name:
Keiko Okada
Email:
Principal Investigator
Facility:
Name:
CHA Bundang Medical Center
Address:
City:
Bundang-Gu, Seongnam-Si
Zip:
13496
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Jaejoon Lim, MD
Email:
coolppeng@naver.com
Investigator:
Last name:
Jaejoon Lim, MD
Email:
Principal Investigator
Facility:
Name:
National Cancer Center
Address:
City:
Ilsandong-Gu, Goyang-Si
Zip:
10408
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Heon Yoo, MD, PhD
Email:
heonyoo@ncc.re.kr
Investigator:
Last name:
Heon Yoo, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Samsung Medical Center
Address:
City:
Gangnam-Gu
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Ji Won Lee, MD, PhD
Email:
leejw.lee@samsung.com
Investigator:
Last name:
Ji Won Lee, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Gangnam Severance Hospital, Yonsei University Health System
Address:
City:
Gangnam
Zip:
06273
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Jun Won Kim, MD, PhD
Email:
junwon@yuhs.ac
Investigator:
Last name:
Jun Won Kim, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Seoul National University Hospital
Address:
City:
Jongno-Gu
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Hyoung Jin Kang, MD
Email:
kanghj@snu.ac.kr
Investigator:
Last name:
Hyoung Jin Kang, MD
Email:
Principal Investigator
Facility:
Name:
Asan Medical Center
Address:
City:
Seoul
Zip:
5505
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Shin Kyo Yoon
Phone:
+82230107813
Email:
shinkyoyoon@amc.seoul.kr
Investigator:
Last name:
Shin Kyo Yoon
Email:
Principal Investigator
Facility:
Name:
Severance Hospital Yonsei University Health System
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Jong Hee Chang, MD, PhD
Email:
changjh@yuhs.ac
Investigator:
Last name:
Jong Hee Chang, MD, PhD
Email:
Principal Investigator
Facility:
Name:
The Catholic University of Korea, Seoul St. Mary's Hospital
Address:
City:
Seoul
Zip:
6591
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Jae-Sung Park, MD, PhD
Email:
jspark82@catholic.ac.kr
Investigator:
Last name:
Jae-Sung Park, MD
Email:
Principal Investigator
Facility:
Name:
Erasmus MC
Address:
City:
Rotterdam
Zip:
3015 GD
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Martin van den Bent, MD, PhD
Email:
m.vandenbent@erasmusmc.nl
Investigator:
Last name:
Martin van den Bent, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Universitair Medisch Centrum Utrecht Cancer Center
Address:
City:
Utrecht
Zip:
3584 CX
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Tom J Snijders
Email:
t.j.snijders@umcutrecht.nl
Investigator:
Last name:
Tom J Snijders
Email:
Principal Investigator
Facility:
Name:
Hospital Sant Joan de Deu
Address:
City:
Esplugues De Llobregat
Zip:
8950
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Vicente Santa-Maria Lopez, MD
Email:
vicente.santamaria@sjd.es
Investigator:
Last name:
Vicente Santa-Maria Lopez, MD
Email:
Principal Investigator
Facility:
Name:
Clinica Universidad Navarra
Address:
City:
Pamplona
Zip:
31008
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Jaime Gallego Perez de Larraya, MD
Email:
jgallego@unav.es
Investigator:
Last name:
Jaime Gallego Perez de Larraya, MD
Email:
Principal Investigator
Facility:
Name:
Hospital Clinic de Barcelona
Address:
City:
Barcelona
Zip:
08036
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Estela Pineda, MD
Email:
epineda@clinic.cat
Investigator:
Last name:
Estela Pineda, MD
Email:
Principal Investigator
Facility:
Name:
Hospital Universitario Vall d'Hebron
Address:
City:
Barcelona
Zip:
8035
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Maria Vieito Villar, MD, MSc
Email:
mvieito@vhio.net
Investigator:
Last name:
Maria Vieito Villar, MD, MSc
Email:
Principal Investigator
Facility:
Name:
Hospital Infantil Universitario Niño Jesus
Address:
City:
Madrid
Zip:
28009
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Alvaro Lassaletta, MD
Email:
lassaalvaro@yahoo.com
Investigator:
Last name:
Alvaro Lassaletta, MD
Email:
Principal Investigator
Facility:
Name:
Hospital Universitario 12 de Octubre
Address:
City:
Madrid
Zip:
28041
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Juan Manuel Sepulveda Sánchez, MD
Email:
sepulvedasanchez@seom.org
Investigator:
Last name:
Juan Manuel Sepulveda Sánchez, MD
Email:
Principal Investigator
Facility:
Name:
Hospital Universitario HM Sanchinarro
Address:
City:
Madrid
Zip:
28050
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Gema Maria Garcia Ledo
Email:
gmgarcialedo@hmhospitales.com
Investigator:
Last name:
Gema Maria Garcia Ledo
Email:
Principal Investigator
Facility:
Name:
Complejo Asistencial Universitario de Salamanca - H. Clinico
Address:
City:
Salamanca
Zip:
37007
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Miguel Navarro Martin, MD
Email:
lmnavarro@saludcastillayleon.es
Investigator:
Last name:
Miguel Navarro Martin, MD
Email:
Principal Investigator
Facility:
Name:
Hospital Universitari i Politecnic La Fe de Valencia
Address:
City:
Valencia
Zip:
46026
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Regina Gironés Sarrió, MD
Email:
girones_reg@gva.es
Investigator:
Last name:
Regina Gironés Sarrió, MD
Email:
Principal Investigator
Facility:
Name:
Hospital Universitari i Politecnic La Fe de Valencia
Address:
City:
Valencia
Zip:
46026
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Antonio Juan Ribelles, MD
Email:
juan_antrib@gva.es
Investigator:
Last name:
Antonio Juan Ribelles, MD
Email:
Principal Investigator
Facility:
Name:
Centre Hospitalier Universitaire Vaudois
Address:
City:
Lausanne
Zip:
1011
Country:
Switzerland
Status:
Recruiting
Contact:
Last name:
Andreas Hottinger, MD, PhD
Email:
andreas.hottinger@chuv.ch
Investigator:
Last name:
Andreas Hottinger, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Universitätsspital Zürich
Address:
City:
Zürich
Zip:
8091
Country:
Switzerland
Status:
Recruiting
Contact:
Last name:
Emilie Le Rhun, MD, PhD
Email:
emilie.lerhun@usz.ch
Investigator:
Last name:
Emilie Le Rhun, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Addenbrooke's Hospital
Address:
City:
Cambridge
Zip:
CB2 0QQ
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Fiona Harris, MBBS, MD
Email:
f.harris3@nhs.net
Investigator:
Last name:
Fiona Harris, MBBS, MD
Email:
Principal Investigator
Facility:
Name:
Beatson West of Scotland Cancer Centre
Address:
City:
Glasgow
Zip:
G12 0YN
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Stefan Nowicki, MD, PhD
Email:
stefan.nowicki@ggc.scot.nhs.uk
Investigator:
Last name:
Stefan Nowicki, MD, PhD
Email:
Principal Investigator
Facility:
Name:
Royal Hospital for Children (Glasgow)
Address:
City:
Glasgow
Zip:
G51 4TF
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Jairam Sastry, MD
Email:
jairam.sastry@ggc.scot.nhs.uk
Investigator:
Last name:
Jairam Sastry, MD
Email:
Principal Investigator
Facility:
Name:
Clatterbridge Cancer Centre - Liverpool
Address:
City:
Liverpool
Zip:
L7 8YA
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Shaveta Mehta, MD, PhD
Email:
shaveta.mehta1@nhs.net
Investigator:
Last name:
Shaveta Mehta, MD, PhD
Email:
Principal Investigator
Facility:
Name:
The Christie NHS Foundation Trust
Address:
City:
Manchester
Zip:
M20 4BX
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Catherine McBain, MD
Email:
catherine.mcbain1@nhs.net
Investigator:
Last name:
Catherine McBain, MD
Email:
Principal Investigator
Facility:
Name:
The Royal Marsden in Sutton, Surrey
Address:
City:
Sutton
Zip:
SM2 5PT
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Fernando Carceller, MD
Email:
fernando.carceller@rmh.nhs.uk
Investigator:
Last name:
Fernando Carceller, MD
Email:
Principal Investigator
Facility:
Name:
Royal Victoria Infirmary
Address:
City:
Newcastle Upon Tyne
Zip:
NE1 4LP
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Joanne Lewis, MRCPCH
Email:
joanne.lewis@nhs.net
Investigator:
Last name:
Joanne Lewis, MRCPCH
Email:
Principal Investigator
Facility:
Name:
Freeman Hospital
Address:
City:
Newcastle Upon Tyne
Zip:
NE7 7DN
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Joanne Lewis, MRCPCH
Email:
joanne.lewis@nhs.net
Investigator:
Last name:
Joanne Lewis, MRCPCH
Email:
Principal Investigator
Facility:
Name:
St James University Hospital
Address:
City:
Leeds
Zip:
LS9 7TF
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Susan Short, MD, MRCPCH
Email:
s.c.short@leeds.ac.uk
Investigator:
Last name:
Susan Short, MD, MRCPCH
Email:
Principal Investigator
Facility:
Name:
The Leeds Teaching Hospitals NHS Trust, Leeds General Infimary
Address:
City:
Leeds
Zip:
LS1 3EX
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Simone Wilkins, MD
Email:
simonewilkins@nhs.net
Investigator:
Last name:
Simone Wilkins, MD
Email:
Principal Investigator
Facility:
Name:
Guy's Hospital
Address:
City:
London
Zip:
SE19RT
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Lucy Brazil, MD
Email:
Lucy.Brazil@gstt.nhs.uk
Investigator:
Last name:
Lucy Brazil, MD
Email:
Principal Investigator
Facility:
Name:
Churchill Hospital
Address:
City:
Oxford
Zip:
Ox3 7LE
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Meera Nandhabalan, MD
Email:
meera.nandhabalan@ouh.nhs.uk
Investigator:
Last name:
Meera Nandhabalan, MD
Email:
Principal Investigator
Start date:
January 23, 2023
Completion date:
August 2026
Lead sponsor:
Agency:
Chimerix
Agency class:
Industry
Source:
Chimerix
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05580562
