Propofol and Sevoflurane Anesthesia in Colorectal Cancer Surgery: Incidence of Acute Kidney Injury

Trial Title: Propofol and Sevoflurane Anesthesia in Colorectal Cancer Surgery: Incidence of Acute Kidney Injury

NCT ID: NCT05585866

Condition: Acute Kidney Injury
Cancer Colorectal

Conditions: Official terms:
Acute Kidney Injury
Wounds and Injuries
Anesthetics

Conditions: Keywords:
sevoflurane
propofol
plasma creatinine

Study type: Observational

Overall status: Active, not recruiting

Study design:

Time perspective: Retrospective

Intervention:

Intervention type: Drug
Intervention name: Anesthesia Agent
Description: The two anesthetic modalities included intravenous propofol anesthesia and sevoflurane gas anesthesia administered according to standard clinical praxis.
Arm group label: Propofol
Arm group label: Sevoflurane

Summary: The goal of this observational study is to compare anesthetic modalities (intravenous propofol anesthesia with sevoflurane gas anesthesia) in patients who underwent colorectal cancer resection surgery regarding the outcome of acute kidney injury. The main questions it aims to answer are: - is there a difference in acute kidney injury incidence in the two anesthetic modalities? - is there a difference in plasma creatinine between the two anesthetic modalities? - are there any patient characteristics or intraoperative factors that effect the incidence of acute kidney injury in either anesthetic modality? The study will analyze data from the CAN clinical trial database. (Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesia, NCT01975064)

Criteria for eligibility:

Study pop:
Patients who underwent colorectal cancer resection surgery and gave consent to participate in the CAN trial.

Sampling method: Probability Sample
Criteria:
Inclusion Criteria: - colorectal surgery and participant in the CAN trial Exclusion Criteria: - missing blood samples

Gender: All

Minimum age: N/A

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: Uppsala University

Address:
City: Uppsala
Zip: 75185
Country: Sweden

Start date: November 22, 2021

Completion date: December 31, 2025

Lead sponsor:
Agency: Uppsala University
Agency class: Other

Source: Uppsala University

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05585866