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Trial Title:
DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic Cancer
NCT ID:
NCT05604573
Condition:
Pancreatic Cancer
Conditions: Official terms:
Pancreatic Neoplasms
Conditions: Keywords:
Pancreatic cancer
Circulating Tumor DNA
DNA mutation
DNA methylation
Study type:
Observational [Patient Registry]
Overall status:
Recruiting
Study design:
Time perspective:
Prospective
Intervention:
Intervention type:
Diagnostic Test
Intervention name:
cell free DNA in blood, genetic mutation in tissue
Description:
Diagnostic test for cell free DNA in blood, genetic mutation in tissue
Arm group label:
control
Arm group label:
pancreatic cancer
Summary:
Based on the cell free nucleic acid analysis information of blood samples and genetic
mutation profile of EUS-FNB tissue from pancreatic cancer, the concordance between them
is evaluated. And based on this information, biomarkers for diagnosis, treatment, and
prognosis of pancreatic cancer are explored.
Criteria for eligibility:
Study pop:
Patients aged 18 or older who diagnosed with pancreatic cancer through histological or
radiologic examination and before treatment begins
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Patients diagnosed with pancreatic cancer through histological or radiologic
examination and before treatment begins
- Patients aged 18 or older who voluntarily agrees to participate in the study and is
willing to understand and comply with the subsequent treatment procedures and sample
collection schedule
- Among patients diagnosed with benign pancreatic diseases (pancreatic cyst, chronic
pancreatitis, etc.), patients who have need for histological examination as control
group
Exclusion Criteria:
- Where the subject himself/herself refuses to fill out the consent form or is unable
to fill out the consent form
- If a laboratory test is impossible due to a qualitative problem with the collected
blood sample
- Where the collected tissue does not contain tissue of the desired malignant or
benign disease
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
Accepts Healthy Volunteers
Locations:
Facility:
Name:
Seoul National University Hospital
Address:
City:
Seoul
Zip:
101
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Sang Hyub Lee, MD PhD
Phone:
+82-2-2072-2228
Email:
gidoctor@snu.ac.kr
Investigator:
Last name:
Sang Hyub Lee, MD PhD
Email:
Principal Investigator
Investigator:
Last name:
Jin Ho Choi, MD
Email:
Sub-Investigator
Start date:
February 9, 2022
Completion date:
December 31, 2024
Lead sponsor:
Agency:
Seoul National University Hospital
Agency class:
Other
Collaborator:
Agency:
GENECAST Co., Ltd.
Agency class:
Other
Source:
Seoul National University Hospital
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05604573
