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Trial Title:
Laser Versus Cryotherapy for the Treatment of Recalcitrant Warts
NCT ID:
NCT05616078
Condition:
Warts
Conditions: Official terms:
Warts
Study type:
Interventional
Study phase:
N/A
Overall status:
Not yet recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
Single (Outcomes Assessor)
Intervention:
Intervention type:
Other
Intervention name:
laser treatment
Description:
a maximum of 4 sessions, with an interval of 3 to 4 weeks
Arm group label:
laser treatment
Intervention type:
Other
Intervention name:
cryotherapy
Description:
a maximum of 4 sessions, with an interval of 3 to 4 weeks
Arm group label:
cryotherapy
Summary:
To evaluate whether laser was superior to cryotherapy for recalcitrant warts
Detailed description:
Patients with recalcitrant warts were randomized equally to receive laser or cryotherapy
every 3 to 4 weeks, for a maximum of 4 sessions.The primary outcomes were the cure rate
at 16 weeks; secondary outcomes included time to clearance of warts, patient satisfaction
with the treatment and treatment-related adverse effects.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Patients with HPV2/27/57-induced recalcitrant warts, including periungualor mosaic
warts, common or plantar warts with a duration of longer than 1 year, and common or
plantar warts previously received no more than two sessions of cryotherapy
- Total number of warts is ≤10 .
- Aged 18 years or older.
Exclusion Criteria:
- Patients are currently participating in another trial for the treatment of cutaneous
warts.
- Patients have taken immunosuppressant drugs (such as oral corticosteroids) during
the past three months.
- Patients have impaired healing eg due to diabetes, vitamin A deficiency,
hyperthyroidism and hypothyroidism.
- Patients have autoimmune diseases (such as systemic lupus erythematosus,
dermatomyositis, scleroderma or other diseases).
- Patients are pregnant or ready for pregnancies or breast-feeding.
- Patients have cold intolerance (such as cold urticaria, cryoglobulinaemia, cold
agglutinin syndrome or Raynaud's syndrome).
- Patients have local pain intolerance.
- Patients have local hypoesthesia.
- Patients are unable to tolerate laser or cryotherapy.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Start date:
November 2022
Completion date:
November 2025
Lead sponsor:
Agency:
The 306 Hospital of People's Liberation Army
Agency class:
Other
Source:
The 306 Hospital of People's Liberation Army
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05616078
