Trial Title:
Cancer Prevention for Young Rural Adults
NCT ID:
NCT05618158
Condition:
Cancer
Conditions: Keywords:
social media
cancer prevention
nicotine use
physical activity
nutrition
sun protection
alcohol use
HPV vaccine
media literacy
Study type:
Interventional
Study phase:
N/A
Overall status:
Enrolling by invitation
Study design:
Allocation:
N/A
Intervention model:
Single Group Assignment
Intervention model description:
Randomized stepped-wedge with four cohorts
Primary purpose:
Prevention
Masking:
None (Open Label)
Intervention:
Intervention type:
Behavioral
Intervention name:
4 Corners Rural Health Cancer Prevention
Description:
Participants, aged 18-26, will join a private Facebook group to participate in the
intervention. The group is not viewable to the public, including other Facebook users.
Content that focuses on cancer prevention behaviors will be posted twice per day for up
to 12 months. Each group will be hosted by a moderator who is responsible for managing
the intervention goals and participants' engagement.
Arm group label:
4 Corners Rural Cancer Prevention
Summary:
Young adults aged 18-26 engage in a number of behaviors that increase their risk of
developing cancer later in life including sedentary lifestyles, unhealthy eating,
nicotine produce us, heavy drinking of alcohol, increased UV exposure, and incomplete
uptake of HPV vaccination. A multi-risk factor campaign will be developed to reduce these
cancer risk behaviors and delivered to young adults over social media, a popular channel
that can reach nearly all young adults. The campaign will be evaluated for effectiveness
in a rigorous randomized trial with measures of moderate to vigorous physical activity,
healthy eating patterns, nicotine product use, alcohol intake, sunburn prevalence, and
HPV vaccination uptake.
Detailed description:
Several risk factors are prevalent during early adulthood that can lead to cancer later
in life. Emerging adults (EAs) aged 18-26 residing in rural areas of the United States
engage in many cancer risk behaviors, especially sedentary lifestyles, poor eating
patterns, nicotine product use, excess alcohol intake, infrequent sun protection, and
inadequate uptake of the HPV vaccine. This application responds to RFA-CA-20-051, "Social
and Behavioral Intervention Research to Address Modifiable Risk Factors for Cancer in
Rural Populations." The goal is to improve cancer risk behavioral factors among diverse
EAs aged 18-26 living in rural counties in the Four Corners states, a unique, underserved
region, using a social media campaign designed with community advisors. EAs, including in
rural communities, are heavy consumers of online content, especially over social media,
and social media provide responsive, engaging, and low-cost platforms for distributing
cancer prevention information with high dissemination potential. But, social media also
circulate inaccurate, misleading, and harmful information. The specific aims of this
research are to: 1) Develop a social media intervention for diverse EAs in rural
communities via a community-engaged process that combines expert advice, user-generated
content, and online instruction to communicate about behavioral cancer risks, cancer
misinformation, counter marketing, digital and media literacy, and family communication;
2) evaluate the effect of a theory-based social media intervention on moderate to
vigorous physical activity (MVPA), healthy eating patterns, nicotine product use, alcohol
intake, sunburn prevalence, and HPV vaccination with the diverse population of EAs aged
18-26 in rural counties in AZ, CO, NM, and UT (Four Corners states) recruited from
Qualtrics' survey panel and enrolled in a pragmatic randomized trial using a
stepped-wedge design in which individual EAs will be randomized to 1 of 4 cohorts and
receive the social media feed for varying durations in separate Facebook private groups;
3) test if improvements in EAs' cancer risk knowledge and beliefs, digital and media
literacy skills, accurate cancer prevention information, and family communication mediate
impact of the social media campaign; and 4) explore whether the impact of the social
media campaign differs according to: a) level of EAs' engagement with campaign, b) cancer
risk factors, and c) biological sex of the participants (as required by NIH). The
research is innovative because it tests a theory-based, multi-risk factor approach to
cancer prevention with diverse EAs in rural counties, an under-studied population, in a
very popular new media. Social media may reach EAs more than interventions through other
community channels (e.g., clinics, schools, and workplaces) and for lower cost in the
geographically-dispersed, underserved rural communities in the Mountain West. The overall
impact is extremely high because it will aid rural EAs in making informed decisions that
reduce cancer risk factors and prevent cancer later in life and help EAs critically
evaluate and resist misinformation and marketing that promote cancer risk behaviors.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Aged 18-26 years old
- Resides in a county coded as RUCC 4-9 in Arizona, Colorado, New Mexico, or Utah
- Able to speak and read English
- Has regular social media engagement
- Accepts screening call from study staff
- Consents to participate
Exclusion Criteria:
- Participated in community engagement activities
- Cannot speak and read English
- Has low or no social media engagement
- Does not accept a screening call from study staff
- Does not consent to participate
- Does not give permission for engagement data to be extracted from Facebook private
group
- If biologically female, currently pregnant
Gender:
All
Minimum age:
18 Years
Maximum age:
26 Years
Healthy volunteers:
Accepts Healthy Volunteers
Locations:
Facility:
Name:
University of Arizona
Address:
City:
Tucson
Zip:
85719
Country:
United States
Facility:
Name:
University of Colorado Denver
Address:
City:
Aurora
Zip:
80045-2570
Country:
United States
Facility:
Name:
Colorado State University
Address:
City:
Fort Collins
Zip:
80521-4593
Country:
United States
Facility:
Name:
University of New Mexico
Address:
City:
Albuquerque
Zip:
87131-0001
Country:
United States
Facility:
Name:
University of Utah
Address:
City:
Salt Lake City
Zip:
84112-5550
Country:
United States
Start date:
April 20, 2024
Completion date:
August 31, 2027
Lead sponsor:
Agency:
Klein Buendel, Inc.
Agency class:
Industry
Collaborator:
Agency:
National Cancer Institute (NCI)
Agency class:
NIH
Collaborator:
Agency:
University of Arizona
Agency class:
Other
Collaborator:
Agency:
University of Utah
Agency class:
Other
Collaborator:
Agency:
Colorado State University
Agency class:
Other
Collaborator:
Agency:
University of Colorado, Denver
Agency class:
Other
Collaborator:
Agency:
University of New Mexico
Agency class:
Other
Source:
Klein Buendel, Inc.
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05618158
