Trial Title:
A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)
NCT ID:
NCT05624554
Condition:
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Conditions: Official terms:
Lymphoma
Leukemia
Leukemia, Lymphoid
Leukemia, Lymphocytic, Chronic, B-Cell
Cyclophosphamide
Bendamustine Hydrochloride
Rituximab
Fludarabine
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
Single (Outcomes Assessor)
Intervention:
Intervention type:
Drug
Intervention name:
Nemtabrutinib
Description:
65 mg administered orally daily until disease progression, unacceptable toxicity, or
discontinuation criteria met.
Arm group label:
Nemtabrutinib
Other name:
MK-1026
Intervention type:
Drug
Intervention name:
Fludarabine
Description:
25 mg/m^2 administered via intravenous (IV) infusion on Days 1, 2, and 3 of each 28-day
cycle up to 6 cycles.
Arm group label:
FCR or BR
Intervention type:
Drug
Intervention name:
Cyclophosphamide
Description:
250 mg/m^2 administered via IV infusion on Days 1, 2, and 3 of each 28-day cycle up to 6
cycles.
Arm group label:
FCR or BR
Intervention type:
Drug
Intervention name:
Bendamustine
Description:
Administered via IV infusion on Days 1 and 2 of each 28-day cycle up to 6 cycles. The
first dose is given as 70 to 90 mg/m^2. Subsequent doses may be escalated up to 90
mg/m^2, if applicable and as per local guidelines.
Arm group label:
FCR or BR
Intervention type:
Biological
Intervention name:
Rituximab
Description:
Administered as an IV infusion on Day 1 of each 28-day cycle. The initial dose is 375
mg/m^2 (cycle 1) followed by 500 mg/m^2 for remaining cycles.
Arm group label:
FCR or BR
Other name:
RITUXAN®/MabThera
Intervention type:
Biological
Intervention name:
Truxima
Description:
Administered as an IV infusion on Day 1 of each 28-day cycle. The initial dose is 375
mg/m^2 (cycle 1) followed by 500 mg/m^2 for remaining cycles.
Arm group label:
FCR or BR
Other name:
Rituximab biosimilar
Intervention type:
Biological
Intervention name:
Ruxience
Description:
Administered as an IV infusion on Day 1 of each 28-day cycle. The initial dose is 375
mg/m^2 (cycle 1) followed by 500 mg/m^2 for remaining cycles.
Arm group label:
FCR or BR
Other name:
Rituximab biosimilar
Intervention type:
Biological
Intervention name:
Riabni
Description:
Administered as an IV infusion on Day 1 of each 28-day cycle. The initial dose is 375
mg/m^2 (cycle 1) followed by 500 mg/m^2 for remaining cycles.
Arm group label:
FCR or BR
Other name:
Rituximab biosimilar
Summary:
Researchers are looking for new ways to treat people with chronic lymphocytic leukemia
(CLL) or small lymphocytic lymphoma (SLL). CLL and SLL are types of blood cancer.
Researchers want to know if people who take nemtabrutinib compared to those who take the
standard treatments in this study will live longer without their cancer growing,
spreading or returning (progression free survival).
Criteria for eligibility:
Criteria:
The main inclusion and exclusion criteria include but are not limited to the following:
Inclusion Criteria:
- Confirmed diagnosis of chronic lymphocytic leukemia (CLL)/ small lymphocytic
lymphoma (SLL) and active disease clearly documented to have a need to initiate
therapy
- Has previously untreated CLL/SLL participants without tumor protein 53 (TP53)
aberrations and documented 11q status and immunoglobulin heavy chain gene (IGHV)
mutational status
- The ability to swallow and retain oral medication
Exclusion Criteria:
- Active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection
- Gastrointestinal dysfunction that may affect drug absorption (eg, gastric bypass
surgery, gastrectomy)
- Known additional malignancy that is progressing or has required active treatment
within the past 3 years, except basal cell carcinoma of skin, squamous cell
carcinoma of skin, or carcinoma in situ (eg, breast carcinoma, cervical cancer in
situ) that have undergone potential curative therapy
- History of severe bleeding disorders
- Not adequately recovered from major surgery or has ongoing surgical complications
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Highlands Oncology Group ( Site 5205)
Address:
City:
Springdale
Zip:
72762
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
479-872-8130
Facility:
Name:
Clermont Oncology Center ( Site 5224)
Address:
City:
Clermont
Zip:
34711
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
352-242-1366
Facility:
Name:
Hattiesburg Clinic Hematology/Oncology ( Site 5216)
Address:
City:
Hattiesburg
Zip:
39401
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
601-261-1700
Facility:
Name:
Medical Oncology Associates, PS ( Site 5206)
Address:
City:
Spokane
Zip:
99208
Country:
United States
Status:
Completed
Facility:
Name:
Royal Adelaide Hospital ( Site 1105)
Address:
City:
Adelaide
Zip:
5000
Country:
Australia
Status:
Completed
Facility:
Name:
Hospital Erasto Gaertner-CEPEP - Pesquisa Clínica ( Site 1317)
Address:
City:
Curitiba
Zip:
81520060
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+55 41 999846033
Facility:
Name:
Hospital Amaral Carvalho-Centro de Pesquisas ( Site 1304)
Address:
City:
Jaú
Zip:
17210-120
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5514991337515
Facility:
Name:
A. C. Camargo Cancer Center ( Site 1318)
Address:
City:
São Paulo
Zip:
01509-010
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+551121895000
Facility:
Name:
Instituto Nacional de Câncer - INCA-Divisão de Pesquisa Clínica e Desenvolvimento Tecnológico HC1 (
Address:
City:
Rio de Janeiro
Zip:
20231-050
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+552199616963
Facility:
Name:
ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO-Pesquisa Clinica ( Site 1308)
Address:
City:
Sao Paulo
Zip:
01246-000
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+5511999014316
Facility:
Name:
Hospital Paulistano-Americas Oncologia ( Site 1302)
Address:
City:
Sao Paulo
Zip:
01321-001
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+5511992926463
Facility:
Name:
Specialized Hospital for Active Treatment of Haematology Diseases ( Site 6403)
Address:
City:
Sofia
Zip:
1797
Country:
Bulgaria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+359879104960
Facility:
Name:
University Multiprofile Hospital for Active Treatment "Sveti Georgi" EAD ( Site 6404)
Address:
City:
Plovdiv
Zip:
4002
Country:
Bulgaria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
00359 888520139
Facility:
Name:
Medical Centre Pratia Clinic EOOD ( Site 6406)
Address:
City:
Plovdiv
Zip:
4003
Country:
Bulgaria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+359 876303522
Facility:
Name:
UMHAT "Prof. Dr. Stoyan Kirkovich"AD-Clinical Hematology ( Site 6400)
Address:
City:
Stara Zagora
Zip:
6003
Country:
Bulgaria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+359 884303483
Facility:
Name:
Multriprofile Hospital for Active Treatment "Hristo Botev" ( Site 6402)
Address:
City:
Vratsa
Zip:
3000
Country:
Bulgaria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
359887881580
Facility:
Name:
James Lind Centro de Investigacion del Cancer ( Site 1503)
Address:
City:
Temuco
Zip:
4800827
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
56974316500
Facility:
Name:
Biocenter ( Site 1507)
Address:
City:
Concepcion
Zip:
4070196
Country:
Chile
Status:
Active, not recruiting
Facility:
Name:
IC La Serena Research ( Site 1506)
Address:
City:
La Serena.
Zip:
1720430
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+56951280903
Facility:
Name:
Centro de Estudios Clínicos SAGA-CECSAGA ( Site 1509)
Address:
City:
Santiago
Zip:
7500653
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+56991612199
Facility:
Name:
FALP-UIDO ( Site 1500)
Address:
City:
Santiago
Zip:
7500921
Country:
Chile
Status:
Active, not recruiting
Facility:
Name:
Clínica Inmunocel ( Site 1511)
Address:
City:
Santiago
Zip:
7580206
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
997890202
Facility:
Name:
Peking University Third Hospital ( Site 1602)
Address:
City:
Beijing
Zip:
100191
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Chongqing University Cancer Hospital ( Site 1605)
Address:
City:
Chongqing
Zip:
400030
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86-13527363925
Facility:
Name:
Chongqing University Three Gorges Hospital ( Site 1609)
Address:
City:
Wanzhou
Zip:
404000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13452762769
Facility:
Name:
Southern Medical University Nanfang Hospital-Department of Hematopathology ( Site 1607)
Address:
City:
Guangzhou
Zip:
510515
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
020-61641615
Facility:
Name:
Sun Yat-sen University Cancer Center ( Site 1608)
Address:
City:
Guangzhou
Zip:
510700
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+8613798032244
Facility:
Name:
The Affiliated Hospital of Guizhou Medical University ( Site 1625)
Address:
City:
Guiyang
Zip:
550004
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0851-86740793
Facility:
Name:
Hainan General Hospital ( Site 1603)
Address:
City:
Haikou
Zip:
570311
Country:
China
Status:
Completed
Facility:
Name:
Henan Cancer Hospital-hematology department ( Site 1613)
Address:
City:
Zhengzhou
Zip:
450008
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 13674902391
Facility:
Name:
Tongji Hospital Tongji Medical,Science & Technology ( Site 1619)
Address:
City:
Wuhan
Zip:
430000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
027-83665006
Facility:
Name:
Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1618)
Address:
City:
Wuhan
Zip:
430010
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
027-84309723
Facility:
Name:
Xiangya Hospital Central South University-Hematology department ( Site 1616)
Address:
City:
Changsha
Zip:
410008
Country:
China
Status:
Completed
Facility:
Name:
Hunan Cancer Hospital ( Site 1615)
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 19918803330
Facility:
Name:
The First Affiliated Hospital of Soochow University-hematology department ( Site 1612)
Address:
City:
Suzhou
Zip:
215006
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13616219570
Facility:
Name:
The First Affiliated Hospital of Nanchang University ( Site 1614)
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13970038386
Facility:
Name:
Jiangxi Provincial Cancer Hospital ( Site 1628)
Address:
City:
Nanchang
Zip:
330029
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13970880559
Facility:
Name:
The First Hospital of Jilin University-Hematology ( Site 1621)
Address:
City:
Changchun
Zip:
130021
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 15843073208
Facility:
Name:
The First Affiliated Hospital of Xi'an Jiaotong University ( Site 1617)
Address:
City:
Xi'an
Zip:
710061
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+029 85324421
Facility:
Name:
Shaanxi provincial people's hospital ( Site 1626)
Address:
City:
Xi'an
Zip:
710068
Country:
China
Status:
Completed
Facility:
Name:
Fudan University Shanghai Cancer Center ( Site 1606)
Address:
City:
Shanghai
Zip:
200032
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
021-64175590-85100
Facility:
Name:
Shanxi Cancer Hospital ( Site 1629)
Address:
City:
Taiyuan
Zip:
030000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+8613835158122
Facility:
Name:
Institute of hematology&blood disease hospital ( Site 1600)
Address:
City:
Tianjin
Zip:
300020
Country:
China
Status:
Active, not recruiting
Facility:
Name:
Tianjin Medical University Cancer Institute & Hospital-lymphoma ( Site 1604)
Address:
City:
Tianjin
Zip:
300060
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 22 2334 0123
Facility:
Name:
The First Affiliated Hospital, Zhejiang University-Hematology ( Site 1611)
Address:
City:
Hangzhou
Zip:
310003
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
057187236898
Facility:
Name:
Clini Salud ( Site 1700)
Address:
City:
Envigado
Zip:
055422
Country:
Colombia
Status:
Completed
Facility:
Name:
Fundacion Colombiana de Cancerología Clinica Vida ( Site 1707)
Address:
City:
Medellin
Zip:
050030
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
3128466807
Facility:
Name:
Sociedad De Oncologia Y Hematologia Del Cesar-Oncology ( Site 1704)
Address:
City:
Valledupar
Zip:
200001
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
3112620177
Facility:
Name:
Oncologos del Occidente ( Site 1706)
Address:
City:
Pereira
Zip:
660001
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
3005088515
Facility:
Name:
Aarhus Universitetshospital, Skejby-Blodsygdomme ( Site 1902)
Address:
City:
Aarhus
Zip:
8200
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
21391053
Facility:
Name:
Aalborg Universitetshospital, Syd ( Site 1901)
Address:
City:
Aalborg
Zip:
9000
Country:
Denmark
Status:
Active, not recruiting
Facility:
Name:
Odense Universitetshospital ( Site 1900)
Address:
City:
Odense C
Zip:
5000
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+4566113333
Facility:
Name:
Vejle Sygehus ( Site 1903)
Address:
City:
Vejle
Zip:
7100
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+45 79406772
Facility:
Name:
MEDI-K ( Site 2401)
Address:
City:
Guatemala
Zip:
01009
Country:
Guatemala
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+50255505555
Facility:
Name:
CELAN,S.A ( Site 2403)
Address:
City:
Guatemala
Zip:
01010
Country:
Guatemala
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+50252002329
Facility:
Name:
Oncomedica-Guatemala ( Site 2402)
Address:
City:
Guatemala
Zip:
01010
Country:
Guatemala
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+50256973689
Facility:
Name:
Queen Mary Hospital ( Site 2500)
Address:
City:
Hksar
Country:
Hong Kong
Status:
Completed
Facility:
Name:
Fejér Megyei Szent György Egyetemi Oktató Kórház ( Site 2609)
Address:
City:
Székesfehérvár
Zip:
8000
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+36203193883
Facility:
Name:
Heves Vármegyei Markhot Ferenc Oktatókórház és Rendelőintézet ( Site 2608)
Address:
City:
Eger
Zip:
3300
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0036704223242
Facility:
Name:
Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókór-Haematológia osztály ( Site 2602)
Address:
City:
Nyiregyhaza
Zip:
4400
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
42599700
Facility:
Name:
Hospital of Lithuanian University of Health Sciences Kauno klinikos-Oncology and Hematology ( Site 3
Address:
City:
Kaunas
Zip:
50161
Country:
Lithuania
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+37037326820
Facility:
Name:
Hospital Sultanah Aminah ( Site 3203)
Address:
City:
Johor Bahru
Zip:
80100
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+6017-719 5440
Facility:
Name:
Hospital Ampang ( Site 3202)
Address:
City:
Ampang
Zip:
68000
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+603-42896559
Facility:
Name:
Centro de Infusion Superare ( Site 3314)
Address:
City:
Ciudad de México
Zip:
03100
Country:
Mexico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+52 55 5264 6440
Facility:
Name:
Health Pharma Professional Research S.A. de C.V: ( Site 3301)
Address:
City:
Ciudad de México
Zip:
03100
Country:
Mexico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5538173808
Facility:
Name:
Centro de Investigacion Clinica Chapultepec ( Site 3309)
Address:
City:
Morelia
Zip:
58260
Country:
Mexico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4431478545
Facility:
Name:
Oaxaca Site Management Organization ( Site 3313)
Address:
City:
Oaxaca
Zip:
68000
Country:
Mexico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
52 9515147056
Facility:
Name:
Samodzielny Publiczny Szpital Kliniczny nr 1-Department of Haematooncology and Bone Marrow Transpla
Address:
City:
Lublin
Zip:
20-081
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
815345468
Facility:
Name:
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Układu Chłonnego ( S
Address:
City:
Warszawa
Zip:
02-781
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
225462223
Facility:
Name:
Uniwersyteckie Centrum Kliniczne-Klinika Hematologii i Transplantologii ( Site 3702)
Address:
City:
Gdansk
Zip:
80-952
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+48585844255
Facility:
Name:
Pratia Onkologia Katowice ( Site 3705)
Address:
City:
Katowice
Zip:
40-519
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+48600388282
Facility:
Name:
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Hematologii i Transplantacji S
Address:
City:
Kielce
Zip:
25-734
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
48793907806
Facility:
Name:
Samodzielny Publiczny Zaklad Opieki Zdrowotnej MSWiA z Warmi-Oddzial Kliniczny Hematologii ( Site 37
Address:
City:
Olsztyn
Zip:
10-228
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+48895398756
Facility:
Name:
Spitalul Clinic Colțea ( Site 4000)
Address:
City:
București
Zip:
030171
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0040722661228
Facility:
Name:
Spitalul Clinic Colțea ( Site 4001)
Address:
City:
București
Zip:
030171
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0040722833451
Facility:
Name:
Institutul Oncologic Cluj ( Site 4002)
Address:
City:
Cluj
Zip:
400015
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0741337480
Facility:
Name:
National Cancer Centre Singapore ( Site 4200)
Address:
City:
Singapore
Zip:
168583
Country:
Singapore
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+65 6436 8088
Facility:
Name:
Tan Tock Seng Hospital ( Site 4202)
Address:
City:
Singapore
Zip:
308433
Country:
Singapore
Status:
Completed
Facility:
Name:
Netcare Pretoria East Hospital-Albert Alberts Stem Cell Transplant Centre ( Site 4401)
Address:
City:
Centurion
Zip:
0181
Country:
South Africa
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
27129932555
Facility:
Name:
Wits Clinical Research ( Site 4403)
Address:
City:
Johannesburg
Zip:
1864
Country:
South Africa
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
27119836501
Facility:
Name:
Groote Schuur Hospital-Clinical Haematology ( Site 4400)
Address:
City:
Cape Town
Zip:
7925
Country:
South Africa
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0727689024
Facility:
Name:
Haemalife ( Site 4407)
Address:
City:
Kuilsriver
Zip:
7580
Country:
South Africa
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+27219006277
Facility:
Name:
Constantiaberg Haematology ( Site 4408)
Address:
City:
Plumstead
Zip:
7800
Country:
South Africa
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0217616600
Facility:
Name:
Mega Medipol-Hematology ( Site 4904)
Address:
City:
Stanbul
Zip:
34214
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
05077078197
Facility:
Name:
Namik Kemal University Medical Faculty-Hematology ( Site 4912)
Address:
City:
Suleymanpasa
Zip:
59100
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
05326347632
Facility:
Name:
Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 4913)
Address:
City:
Ankara
Zip:
06100
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+90 505 502 50 50
Facility:
Name:
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi ( Site 4906)
Address:
City:
Istanbul
Zip:
34722
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+905324089525
Facility:
Name:
Ege Universitesi Hastanesi ( Site 4902)
Address:
City:
İzmir
Zip:
35100
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+905325566128
Facility:
Name:
MNPE ClinCenter of Oncology,Hematology,Transplantology and Palliative Care of CherkasyRegCouncil ( S
Address:
City:
Cherkassy
Zip:
18009
Country:
Ukraine
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+380634253209
Facility:
Name:
Communal non-profit enterprise "Regional clinical hospital o-Hematology Department ( Site 5113)
Address:
City:
Ivano-Frankivsk
Zip:
76008
Country:
Ukraine
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
380974668727
Facility:
Name:
Nonprofit Organization National Cancer Institute ( Site 5103)
Address:
City:
Kyiv
Zip:
03022
Country:
Ukraine
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
380672091427
Facility:
Name:
Institute of Blood Pathology and Transfusion Medicine of National Aсademy of Medical Sciences of Ukr
Address:
City:
Lviv
Zip:
79057
Country:
Ukraine
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+380 987529801
Facility:
Name:
National Research Center for Radiation Medicine of National Academy of Medical Sciences of Ukraine (
Address:
City:
Kyiv
Zip:
03115
Country:
Ukraine
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
380 67 4443800
Facility:
Name:
Public Non-Profit Enterprise Kyiv City Clinical Hospital #9 -Hematology department #1 ( Site 5111)
Address:
City:
Kyiv
Zip:
04112
Country:
Ukraine
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+380509105840
Start date:
March 16, 2023
Completion date:
March 17, 2031
Lead sponsor:
Agency:
Merck Sharp & Dohme LLC
Agency class:
Industry
Source:
Merck Sharp & Dohme LLC
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05624554
https://www.merckclinicaltrials.com/
https://trialstransparency.merckclinicaltrials.com/Study.aspx?id=1026-008&kw=1026-008
