To hear about similar clinical trials, please enter your email below
Trial Title:
Neo-adjuvant Chemotherapy Evluation in Gastric Cancer Patients Based on Circulating Exosomal LncRNA-GC1
NCT ID:
NCT05647941
Condition:
Gastric Cancer
Chemotherapy Effect
Conditions: Official terms:
Stomach Neoplasms
Conditions: Keywords:
Circulating exosomal lncRNA-GC1
Advanced Gastric Carcinoma
treatment response
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Retrospective
Intervention:
Intervention type:
Diagnostic Test
Intervention name:
Detection of levels of circulating EV-derived lncRNA-GC1
Description:
For patients with gastric cancer receiving neo-adjuvant chemotherapy, the dynamic changes
of EV-derived lncRNA-GC1 was detected to identify whether is can serve as a monitoring
biomarker for treatment response.
Summary:
The investigators hope that through the analysis and research to find determine whether
lncRNA-GC1 could serve as a non-invasive biomarker for monitoring the neo-adjuvant
chemotherapy response for personalized medicine for gastric cancer.
Detailed description:
The LncRNA-GC1could noninvasively track dynamics of tumor burden and has been proposed as
a real-time biomarker that can provide both predictive and prognostic values. But the
value in monitoring the neo-adjuvant chemotherapy response is unclear. The investigators
hope that through the analysis and research to find determine whether lncRNA-GC1 could
serve as a monitoring biomarker for patients with gastric cancer receiving neo-adjuvant
chemotherapy.
Criteria for eligibility:
Study pop:
Community Sample Shanxi - Hospital and community sample Beijing -Hospital
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Having signed informed consent
- Ageā„ 18 years old
- Histologically confirmed gastric adenocarcinoma
- radiographically identified as advanced gastric cancer
Exclusion Criteria:
- Other previous malignancy within 5 year
- Surgery (excluding diagnostic biopsy) within 4 weeks prior to study
- Pregnancy or lactation period
- Legal incapacity
Gender:
All
Minimum age:
18 Years
Maximum age:
80 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Chinese PLA General Hospital Ethics Committee
Address:
City:
Beijing
Zip:
100853
Country:
China
Status:
Recruiting
Contact:
Last name:
XinXin Wang, MD
Phone:
86-13354879656
Email:
wangxinxin@sina.com
Start date:
January 1, 2018
Completion date:
December 30, 2022
Lead sponsor:
Agency:
Chinese PLA General Hospital
Agency class:
Other
Source:
Chinese PLA General Hospital
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05647941
