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Trial Title:
Impact of the Development of Pediatric Palliative Care
NCT ID:
NCT05660499
Condition:
Primary Brain Tumor
Conditions: Official terms:
Brain Neoplasms
Conditions: Keywords:
Primary Brain Tumor
Pediatric Palliative Care
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Retrospective
Summary:
Despite medical advances, cancer remains the leading cause of death by disease in
children.
Brain tumors are the second most common cause of cancer in children after leukemia,
representing 25% of pediatric cancers.
The overall survival rate is about 50% with extremes ranging from less than 5% to more
than 90% depending on the histological type of brain tumor.
The end of life of children with a brain tumor is marked by the possibility of discomfort
symptoms, painful or not, and by a progressive neurological deterioration, which makes
the management of these children complex for both families and health professionals.
Over the last decade, the concept of palliative care has been increasingly integrated
into pediatric onco-hematology services with the primary objective of better symptom
control in a global approach to the child and his or her family in order to aim at a
better quality of life.
Detailed description:
The main objective of the study is to compare the occurrence and management of
end-of-life symptoms in children who died of a primary brain tumor over 2 periods, in
2009 - 2010 and in 2019 - 2020, followed in the Pediatric Oncology departments of
Strasbourg, Besançon, Dijon, Nancy and Reims.
Criteria for eligibility:
Study pop:
- Patient less than 17 years of age suffering from a primary brain tumor
Sampling method:
Non-Probability Sample
Criteria:
Inclusion criteria:
- Patient less than 17 years of age
- Suffering from a primary brain tumor
- Died during the period 2009-2010 or during the period 2019-2020
- Follow-up in one of the Pediatric Oncology departments participating in the study
(Strasbourg, Besançon, Dijon, Nancy and Reims)
- Absence of refusal expressed in the medical file by the parents or the holder(s) of
parental authority concerning the reuse of the child's personal data for research
purposes.
Exclusion criteria:
- Refusal expressed in the medical file by the parents or the holder(s) of parental
authority concerning the reuse of the child's personal data for research purposes
- Patient with a brain tumor secondary to another cancer
Gender:
All
Minimum age:
1 Year
Maximum age:
17 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Service de soins Palliatifs - CHU de Strasbourg - France
Address:
City:
Strasbourg
Zip:
67091
Country:
France
Status:
Recruiting
Contact:
Last name:
Nadine COJEAN, MD
Phone:
33 6 21 11 16 01
Email:
nadine.cojean@chru-strasbourg.fr
Investigator:
Last name:
Nadine COJEAN, MD
Email:
Principal Investigator
Investigator:
Last name:
Marie-Ange LOMBARD, MD
Email:
Sub-Investigator
Investigator:
Last name:
Ludovic MANSUY, MD
Email:
Sub-Investigator
Investigator:
Last name:
Odile ONOIZET-YVERNEAU, MD
Email:
Sub-Investigator
Investigator:
Last name:
Sandra FRACHE, MD
Email:
Sub-Investigator
Investigator:
Last name:
Claire BRIANDET, MD
Email:
Sub-Investigator
Start date:
February 15, 2021
Completion date:
December 31, 2023
Lead sponsor:
Agency:
University Hospital, Strasbourg, France
Agency class:
Other
Source:
University Hospital, Strasbourg, France
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05660499
