Radiographic Prediction of the Nerve Origin of Neck Peripheral Nerve Sheath Tumors

Trial Title: Radiographic Prediction of the Nerve Origin of Neck Peripheral Nerve Sheath Tumors

NCT ID: NCT05684835

Condition: Peripheral Nerve Sheath Tumors
Schwannoma of Neck

Conditions: Official terms:
Neurilemmoma
Nerve Sheath Neoplasms

Study type: Observational

Overall status: Recruiting

Study design:

Time perspective: Retrospective

Intervention:

Intervention type: Procedure
Intervention name: Excision
Description: All patients underwent surgery under general anesthesia and intraoperative neuromonitoring according to the preoperatively predicted NO. Using an anterior cervical approach, the tumor was delineated after identifying the relationships among the great vessels, nerves, and tumors. The NO was confirmed intraoperatively. Sharp dissection was performed meticulously to enucleate the tumor from the NO to preserve most nerve fibers.
Arm group label: Cervical spinal nerve tumor group
Arm group label: Sympathetic nerve tumor group
Arm group label: Vagus nerve tumor group

Summary: Postoperative nerve palsy is a major complication following resection of neck peripheral nerve sheath tumors. This study is a retrospective cohort aimed to predict the nerve origin of neck peripheral nerve sheath tumors. Accurate preoperative identification of the nerve origin can improve surgical outcomes and patient counseling

Detailed description: Postoperative nerve palsy is a major complication following resection of neck peripheral nerve sheath tumors (PNSTs). Accurate preoperative identification of the nerve origin (NO) can improve surgical outcomes and patient counseling. This study aims to predict the NO of neck PNSTs with radiographic analysis. This study is a retrospective cohort analysis. Radiographic parameters will be reviewed and the sensitivity, specificity, accuracy of NO prediction will be evaluated.

Criteria for eligibility:

Study pop:
Patients with an intraoperatively confirmed neck PNST and NO between January 2008 and December 2022 who underwent surgical excision of neck PNST with anterior approach, excluding patients with previous anterior neck surgery, malignant disease, prior neck radiation, and undetermined intraoperative NO.

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: - Patients with clinical diagnosis of neck peripheral nerve sheath tumors. - Patients received surgery January 2008 and December 2022. - The nerve origin of peripheral nerve sheath tumor must be intraoperatively confirmed. Exclusion Criteria: - Previous anterior neck surgery. - Malignant disease. - Prior neck radiation. - Undetermined intraoperative nerve origin.

Gender: All

Minimum age: 20 Years

Maximum age: 80 Years

Healthy volunteers: No

Locations:

Facility:
Name: National Cheng-Kung University Hospital

Address:
City: Taipei
Zip: 704
Country: Taiwan

Status: Recruiting

Contact:
Last name: Chi-Chen Huang, MD

Phone: 06-2353535

Phone ext: 258821
Email: charles042085@hotmail.com

Start date: January 1, 2008

Completion date: June 1, 2023

Lead sponsor:
Agency: National Cheng-Kung University Hospital
Agency class: Other

Source: National Cheng-Kung University Hospital

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05684835