Retrospective Review of Esophageal Cancer at MSKCC

Trial Title: Retrospective Review of Esophageal Cancer at MSKCC

NCT ID: NCT05706558

Condition: Esophageal Cancer
Esophagus Cancer

Conditions: Official terms:
Esophageal Neoplasms

Conditions: Keywords:
Esophageal Cancer
Esophagus Cancer
Memorial Sloan Kettering Cancer Center
16-1631

Study type: Observational

Overall status: Recruiting

Study design:

Time perspective: Retrospective

Intervention:

Intervention type: Procedure
Intervention name: Esophagectomy
Description: Esophagectomy
Arm group label: Circumferential resection margin (CRM)
Arm group label: Circumferential resection margin (CRM)+
Arm group label: Circumferential resection margin (CRM)-close

Summary: Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.

Criteria for eligibility:

Study pop:
Participants undergoing esophagectomy for histologically confirmed esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) during the period from 2000 to 2019.

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: - Histologically confirmed esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy - Pathologic staged T3 tumors (pT3) Exclusion Criteria: - Pathologic staged T0-2 (pT0-2) or T4 tumors (pT4) - Patients with histologic types other than EAC or ESCC, dysplasia or carcinoma in situ without tumor invasion, - Patients undergoing salvage esophagectomy - Evidence of distant metastatic disease - Patients with a positive proximal or distal margin

Gender: All

Minimum age: 18 Years

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: Memorial Sloan Kettering Cancer Center (All Protocol Activities)

Address:
City: New York
Zip: 10065
Country: United States

Status: Recruiting

Contact:
Last name: Daniela Molena, MD

Phone: 212-639-3870

Start date: December 13, 2016

Completion date: February 2025

Lead sponsor:
Agency: Memorial Sloan Kettering Cancer Center
Agency class: Other

Source: Memorial Sloan Kettering Cancer Center

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05706558
http://www.mskcc.org