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Trial Title:
Familial B-cell Lymphoproliferative Disorders
NCT ID:
NCT05718986
Condition:
Lymphoproliferative Disorders
Premalignant
Monoclonal B-Cell Lymphocytosis
Chronic Lymphocytic Leukemia
Conditions: Official terms:
Leukemia, Lymphoid
Leukemia, Lymphocytic, Chronic, B-Cell
Precancerous Conditions
Lymphoproliferative Disorders
Lymphocytosis
Conditions: Keywords:
lymphoproliferative disorders
Chronic Lymphocytic Leukemia
Monoclonal B-cell Lymphocytosis
Study type:
Observational [Patient Registry]
Overall status:
Not yet recruiting
Study design:
Time perspective:
Other
Intervention:
Intervention type:
Other
Intervention name:
No intervention
Description:
No intervention
Arm group label:
Assuta Ashdod Hospital
Arm group label:
Beilinson Hospital
Arm group label:
Bnai Zion Medical Center
Arm group label:
Emek Medical Center
Arm group label:
Galil Medical Center
Arm group label:
Hadassah Medical Center
Arm group label:
Kaplan Medical Center
Arm group label:
Meir Medical Center
Arm group label:
Rambam Medical Center
Arm group label:
Shaare Zdek Medical Center
Arm group label:
Shamir Medical Center (Assaf Harofeh)
Arm group label:
Sheba Medical Center
Arm group label:
Soroka Medical Center
Arm group label:
Tel Aviv Sourasky Medical Center - Ichilov Hospital
Arm group label:
Ziv Medical Center
Summary:
This study investigates families with at least two cases of B-cell lymphoproliferative
disorders (LPD), and evaluates the prevalence of LPD in families, the relationship
between medical history, genetic factors, and the risk of familial LPD, and various
clinical outcomes for these families in a multiethnic population of Jews and Arabs in
Israel.
Criteria for eligibility:
Study pop:
Jewish and Arab LPD families with at least 2 family members with LPD.
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Patient inclusion criteria:
Patients must have LPD and must have a family history of LPD. LPD patients who signed an
informed consent to participate in the study.
Criteria for the inclusion of relatives of patients:
Relatives must be related by blood to LPD patients or unrelated (for control group).
Relatives who signed an informed consent to participate in the study.
Exclusion Criteria:
- Pregnant women, special populations and those lacking judgment will not be included
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
Accepts Healthy Volunteers
Start date:
June 2024
Completion date:
December 2040
Lead sponsor:
Agency:
University of Haifa
Agency class:
Other
Collaborator:
Agency:
Bnai Zion Medical Center
Agency class:
Other
Source:
University of Haifa
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05718986
