Trial Title:
A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma
NCT ID:
NCT05730036
Condition:
Relapsed Refractory Multiple Myeloma (RRMM)
Conditions: Official terms:
Multiple Myeloma
Neoplasms, Plasma Cell
Dexamethasone
Pomalidomide
Elotuzumab
Conditions: Keywords:
BCMA X CD3 Bispecific Monoclonal Antibody
CD38 antibody
Proteasome inhibitor
Lenalidomide
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Linvoseltamab
Description:
REGN5458 will be administered by intravenous (IV) infusion
Arm group label:
Linvoseltamab
Other name:
REGN5458
Intervention type:
Drug
Intervention name:
Elotuzumab
Description:
Elotuzumab will be administered by IV infusion
Arm group label:
Elotuzumab/Pomalidomide/Dexamethasone (EPd)
Other name:
Empliciti
Intervention type:
Drug
Intervention name:
Pomalidomide
Description:
Pomalidomide capsules will administered by mouth (PO)
Arm group label:
Elotuzumab/Pomalidomide/Dexamethasone (EPd)
Other name:
Pomalyst
Intervention type:
Drug
Intervention name:
Dexamethasone
Description:
Dexamethasone tablets/capsules will be administered PO and/or by IV infusion
Arm group label:
Elotuzumab/Pomalidomide/Dexamethasone (EPd)
Other name:
Decadron
Summary:
This study is researching an experimental drug called linvoseltamab, also called
REGN5458.
Linvoseltamab has previously been studied by itself (without other cancer drugs) in
participants who had advanced multiple myeloma that returned and needed to be treated
again after many other therapies had failed. These participants were no longer benefiting
from standard medications and had no good treatment options. In that study, some
participants who were treated with linvoseltamab had improvement of their myeloma
(shrinkage of their tumors), including some participants who had complete responses (that
is, the treatment got rid of all evidence of myeloma in their bodies).
This study is focused on participants who have multiple myeloma that has returned or
needs to be treated again after one to four prior treatments and have standard cancer
treatment options available to them. The aim of this study is to see how safe and
effective linvoseltamab is compared to a combination of three cancer drugs: elotuzumab,
pomalidomide and dexamethasone, (called EPd) in participants who have returned after
having received prior treatment that included lenalidomide, a proteosome inhibitor, and
(for participants in some countries) a cluster of differentiation 38 (CD38) antibody.
Half of the participants in this study will get linvoseltamab, and the other half will
get EPd.
This study is looking at several other research questions, including:
- How long participants benefit from receiving linvoseltamab compared with EPd
- How many participants treated with linvoseltamab or EPd have improvement of their
multiple myeloma and by how much
- What side effects happen from taking linvoseltamab compared to EPd
- How long participants live while receiving treatment or after treatment with
linvoseltamab compared to EPd
- If there is any improvement in pain after treatment with linvoseltamab compared to
EPd
Criteria for eligibility:
Criteria:
Key Inclusion Criteria:
1. Age 18 years or older (or legal adult age in the country) at the time of the
screening visit.
2. Eastern Cooperative Oncology Group (ECOG) performance status ≤1. Patients with ECOG
2 solely due to local symptoms of myeloma (eg. pain) may be allowed after discussion
with the Medical Monitor.
3. Received at least 1 and no more than 4 prior lines of anti-neoplastic MM therapies,
including lenalidomide and a proteasome inhibitor and demonstrated disease
progression on or after the last therapy as defined by the 2016 IMWG criteria.
Participants who have received only 1 line of prior line of antimyeloma therapy must
be lenalidomide refractory, as described in the protocol.
Note: Participants in Israel also must have previously received a CD38 antibody.
Participants in the EU and the UK must have previously received 2 to 4 prior lines
of therapy, including a CD38 antibody.
4. Patients must have measurable disease for response assessment as per the 2016 IMWG
response assessment criteria, as described in the protocol
5. Adequate hematologic, hepatic, renal and cardiac function, as well as evidence of
adequate bone marrow reserves
6. Life expectancy of at least 6 months
Key Exclusion Criteria:
1. Diagnosis of plasma cell leukemia, amyloidosis, Waldenström macroglobulinemia, or
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein,
and skin changes).
2. Prior treatment with elotuzumab and/or pomalidomide
3. Participants with known MM brain lesions or meningeal involvement
4. Treatment with any systemic anti-cancer therapy within 5 half-lives or within 28
days before first administration of study drug, whichever is shorter
5. History of allogeneic stem cell transplantation within 6 months, or autologous stem
cell transplantation within 12 weeks of the start of study treatment. Participants
who have received an allogeneic transplant must be off all immunosuppressive
medications for 6 weeks without signs of graft-versus-host disease. Steroids at
doses equivalent to suppletion doses may be acceptable.
6. Prior treatment with B-cell maturation antigen (BCMA) directed immunotherapies Note:
BCMA antibody-drug conjugates are allowed.
7. History of progressive multifocal leukoencephalopathy (PML), known or suspected PML,
or history of a neurocognitive condition or central nervous system (CNS) movement
disorder.
8. Any infection requiring hospitalization or treatment with IV anti-infectives within
2 weeks of first administration of study drug
9. Uncontrolled infection with human immunodeficiency virus (HIV), hepatitis B virus
(HBV) or hepatitis C virus (HCV); or another uncontrolled infection, as defined in
the protocol.
NOTE: Other protocol defined inclusion/exclusion criteria apply
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
UCLA
Address:
City:
Los Angeles
Zip:
90095
Country:
United States
Status:
Recruiting
Facility:
Name:
University of Florida
Address:
City:
Gainesville
Zip:
32611-5500
Country:
United States
Status:
Withdrawn
Facility:
Name:
University of Kentucky
Address:
City:
Lexington
Zip:
40536
Country:
United States
Status:
Recruiting
Facility:
Name:
Norton Cancer Institute - St. Matthews Campus
Address:
City:
Louisville
Zip:
40207
Country:
United States
Status:
Recruiting
Facility:
Name:
Stony Brook University Hospital
Address:
City:
Stony Brook
Zip:
11794
Country:
United States
Status:
Recruiting
Facility:
Name:
Levine Cancer Center
Address:
City:
Charlotte
Zip:
28204
Country:
United States
Status:
Recruiting
Facility:
Name:
Duke University Medical Center
Address:
City:
Durham
Zip:
27710
Country:
United States
Status:
Recruiting
Facility:
Name:
Kaiser Permanente Northwest
Address:
City:
Portland
Zip:
97227
Country:
United States
Status:
Recruiting
Facility:
Name:
University of Washington-Seattle Cancer Care Alliance
Address:
City:
Seattle
Zip:
98109
Country:
United States
Status:
Recruiting
Facility:
Name:
Royal Prince Alfred Hospital
Address:
City:
Camperdown
Zip:
2050
Country:
Australia
Status:
Recruiting
Facility:
Name:
Royal North Shore Hospital
Address:
City:
St Leonards
Zip:
2065
Country:
Australia
Status:
Recruiting
Facility:
Name:
Royal Brisbane Hospital
Address:
City:
Herston
Zip:
4029
Country:
Australia
Status:
Recruiting
Facility:
Name:
Integrated Clinical Oncology Network
Address:
City:
South Brisbane
Zip:
4101
Country:
Australia
Status:
Recruiting
Facility:
Name:
Royal Adelaide hospital
Address:
City:
Adelaide
Zip:
5000
Country:
Australia
Status:
Recruiting
Facility:
Name:
Royal Hobart Hospital
Address:
City:
Hobart
Zip:
7000
Country:
Australia
Status:
Recruiting
Facility:
Name:
Launceston General Hospital
Address:
City:
Launceston
Zip:
7250
Country:
Australia
Status:
Recruiting
Facility:
Name:
University Hospital Geelong
Address:
City:
Geelong
Zip:
3220
Country:
Australia
Status:
Recruiting
Facility:
Name:
Austin Hospital
Address:
City:
Heidelberg
Zip:
3084
Country:
Australia
Status:
Recruiting
Facility:
Name:
St Vincents Hospital Melbourne
Address:
City:
Melbourne
Zip:
3065
Country:
Australia
Status:
Recruiting
Facility:
Name:
One Clinical Research
Address:
City:
Nedlands
Zip:
6009
Country:
Australia
Status:
Recruiting
Facility:
Name:
Algemeen Ziekenhuis Delta
Address:
City:
Roeselare
Zip:
8800
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Cliniques universitaires Saint Luc
Address:
City:
Brussels
Zip:
1200
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Hospital Sao Rafael
Address:
City:
Salvador
Zip:
41253-190
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Associacao Dr Bartholomeu Tacchini (Instituto Tacchini De Pesquisa Em Saude)
Address:
City:
Bento Goncalves
Zip:
95700084
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Mae de Deus Center
Address:
City:
Porto Alegre
Zip:
90110-270
Country:
Brazil
Status:
Recruiting
Facility:
Name:
ANIMI
Address:
City:
Lages
Zip:
88501-001
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Erasto Gaertner
Address:
City:
Curitiba
Zip:
81520-060
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital de Clinicas de Porto Alegre
Address:
City:
Porto Alegre
Zip:
90035903
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Instituto Americas de Ensino e Pesquisa
Address:
City:
Rio de Janeiro
Zip:
22793-08
Country:
Brazil
Status:
Recruiting
Facility:
Name:
A Beneficência Portuguesa de Sao Paulo
Address:
City:
São Paulo
Zip:
01321000
Country:
Brazil
Status:
Recruiting
Facility:
Name:
AC Camargo Cancer Center
Address:
City:
São Paulo
Zip:
01509-010
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Instituto D'Or de Pesquisa e Ensino
Address:
City:
São Paulo
Zip:
04501-000
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinica Medica Sao Germano
Address:
City:
São Paulo
Zip:
04537-080
Country:
Brazil
Status:
Recruiting
Facility:
Name:
The Ottawa Hospital
Address:
City:
Ottawa
Zip:
K1H 8L6
Country:
Canada
Status:
Recruiting
Facility:
Name:
University Health Network (UHN) - Princess Margaret Cancer Centre
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Facility:
Name:
Odette Sunnybrook Cancer Centre
Address:
City:
Toronto
Zip:
M5P 1V1
Country:
Canada
Status:
Recruiting
Facility:
Name:
Fundacion Arturo Lopez Perez
Address:
City:
Santiago
Zip:
7501066
Country:
Chile
Status:
Recruiting
Facility:
Name:
Hopital Haut leveque-service d'Hematologie
Address:
City:
Pessac
Zip:
33600
Country:
France
Status:
Recruiting
Facility:
Name:
Institut Gustave Roussy-Gustave Roussy Cancer Center -DITEP
Address:
City:
Villejuif
Zip:
94800
Country:
France
Status:
Recruiting
Facility:
Name:
Centre Hospitalier Universitaire (CHU) de Lille
Address:
City:
Lille
Zip:
59037
Country:
France
Status:
Suspended
Facility:
Name:
Centre Léon Bérard
Address:
City:
Lyon
Zip:
69008
Country:
France
Status:
Recruiting
Facility:
Name:
Institut Curie
Address:
City:
Paris
Zip:
75005
Country:
France
Status:
Recruiting
Facility:
Name:
Hôpital Saint Louis, APHP
Address:
City:
Paris
Zip:
75010
Country:
France
Status:
Recruiting
Facility:
Name:
Hopital Universitaire Necker
Address:
City:
Paris
Zip:
75015
Country:
France
Status:
Recruiting
Facility:
Name:
Hopital Saint Antoine
Address:
City:
Paris
Zip:
75571
Country:
France
Status:
Recruiting
Facility:
Name:
University Tuebingen, Medizinische Klinik II
Address:
City:
Tuebingen
Zip:
72076
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitätsklinikum Leipzig
Address:
City:
Leipzig
Zip:
D-04103
Country:
Germany
Status:
Recruiting
Facility:
Name:
University Medical Center Hamburg-Eppendorf
Address:
City:
Hamburg
Zip:
20246
Country:
Germany
Status:
Recruiting
Facility:
Name:
The Chaim Sheba Medical Center
Address:
City:
Ramat Gan
Zip:
5265601
Country:
Israel
Status:
Recruiting
Facility:
Name:
Rambam health care Campus
Address:
City:
Haifa
Zip:
3109601
Country:
Israel
Status:
Recruiting
Facility:
Name:
Carmel Medical Center
Address:
City:
Haifa
Zip:
3436212
Country:
Israel
Status:
Recruiting
Facility:
Name:
Shaare Zedek Medical Center
Address:
City:
Jerusalem
Zip:
91031
Country:
Israel
Status:
Recruiting
Facility:
Name:
Hadassah Medical Center
Address:
City:
Jerusalem
Zip:
91120
Country:
Israel
Status:
Recruiting
Facility:
Name:
Tel Aviv Sourasky Medical Center
Address:
City:
Tel Aviv
Zip:
64239
Country:
Israel
Status:
Recruiting
Facility:
Name:
Casa Sollievo della Sofferenza IRCCS
Address:
City:
San Giovanni Rotondo
Zip:
71013
Country:
Italy
Status:
Recruiting
Facility:
Name:
Istituto Romagnolo per lo Studio Dei Tumori "Dino Amadori"
Address:
City:
Meldola
Zip:
47014
Country:
Italy
Status:
Recruiting
Facility:
Name:
Ospedale Di Circolo - Fondazione Macchi
Address:
City:
Varese
Zip:
21100
Country:
Italy
Status:
Recruiting
Facility:
Name:
AO SS Antonio e Biagio e Cesare Arrigo
Address:
City:
Alessandria
Zip:
10125
Country:
Italy
Status:
Recruiting
Facility:
Name:
AOU Ospedali Riuniti di Ancona
Address:
City:
Ancona
Zip:
60126
Country:
Italy
Status:
Recruiting
Facility:
Name:
Irccs Aou Di Bologna- Policlinico Di Sant'Orsola Malpighi
Address:
City:
Bologna
Zip:
40138
Country:
Italy
Status:
Recruiting
Facility:
Name:
Ospedale Policlinico San Martino IRCCS
Address:
City:
Genova
Zip:
16132
Country:
Italy
Status:
Recruiting
Facility:
Name:
IRCCS Fondazione Policlinico San Matteo Pavia
Address:
City:
Pavia
Zip:
27100
Country:
Italy
Status:
Recruiting
Facility:
Name:
U.O.C. Ematologia Ospedale Santa Maria delle Croci
Address:
City:
Ravenna
Zip:
48121
Country:
Italy
Status:
Recruiting
Facility:
Name:
AUSL IRCCS OF Reggio Emilia
Address:
City:
Reggio Emilia
Zip:
42123
Country:
Italy
Status:
Recruiting
Facility:
Name:
University of Torino, Division of Hematology
Address:
City:
Torino
Zip:
10126
Country:
Italy
Status:
Recruiting
Facility:
Name:
Candiolo Cancer Institute, FPO, IRCCS
Address:
City:
Turin
Zip:
10060
Country:
Italy
Status:
Recruiting
Facility:
Name:
Istituto Oncologico del Mediterraneo (IOM)
Address:
City:
Viagrande
Zip:
95035
Country:
Italy
Status:
Recruiting
Facility:
Name:
Inje University Busan Paik Hospital
Address:
City:
Busan
Zip:
47392
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Pusan National University Hospital
Address:
City:
Busan
Zip:
49241
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Chonnam National University Hwasun Hospital
Address:
City:
Hwasun
Zip:
58128
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Gachon University Gil Medical Center
Address:
City:
Incheon
Zip:
28265
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Jeonbuk National University Hospital
Address:
City:
Jeonju
Zip:
54907
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Seoul National University Hospital
Address:
City:
Seoul
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Severance Hospital
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Asan Medical Center
Address:
City:
Seoul
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Samsung Medical Center
Address:
City:
Seoul
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
The Catholic University of Korea Seoul St. Marys Hospital
Address:
City:
Seoul
Zip:
06591
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Radboud umc
Address:
City:
Nijmegen
Zip:
6500 HB
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Albert Schweitzer Hospital
Address:
City:
Dordrecht
Zip:
3318 AT
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Wielospecjalistyczne Centrum Onkologii i Traumatologii
Address:
City:
Lodz
Zip:
93-510
Country:
Poland
Status:
Recruiting
Facility:
Name:
Uniwersyteckie Centrum Kliniczne
Address:
City:
Gdańsk
Zip:
80-219
Country:
Poland
Status:
Recruiting
Facility:
Name:
Pratia Onkologia Katowice
Address:
City:
Katowice
Zip:
40-519
Country:
Poland
Status:
Recruiting
Facility:
Name:
National University Hospital
Address:
City:
Kent Ridge
Zip:
119074
Country:
Singapore
Status:
Recruiting
Facility:
Name:
Singapore General Hospital
Address:
City:
Singapore
Zip:
169856
Country:
Singapore
Status:
Recruiting
Facility:
Name:
Hospital de Cabueñes
Address:
City:
Gijon
Zip:
33203
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Central de Asturias
Address:
City:
Oviedo
Zip:
33011
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital universitari Son LLatzer
Address:
City:
Palma de Mallorca
Zip:
07198
Country:
Spain
Status:
Recruiting
Facility:
Name:
Institut Catala dOncologia, Hospital Germans Trias i Pujol
Address:
City:
Badalona
Zip:
08916
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitari Mutua de Terrassa
Address:
City:
Terrassa
Zip:
08221
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Marqués de Valdecilla
Address:
City:
Santander
Zip:
39008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitari Son Espases
Address:
City:
Palma de Mallorca
Zip:
07120
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Puerta de Hierro
Address:
City:
Majadahonda
Zip:
28220
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Quirónsalud Madrid
Address:
City:
Pozuelo
Zip:
28223
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario de Navarra
Address:
City:
Pamplona
Zip:
31008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Gral. Universitari D'Alacant Y C.E Babel (Hospital General De Alicante)
Address:
City:
Alicante
Zip:
03010
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital de la Santa Creu I de Sant Pau
Address:
City:
Barcelona
Zip:
08026
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Clinic de Barcelona
Address:
City:
Barcelona
Zip:
08036
Country:
Spain
Status:
Recruiting
Facility:
Name:
Institut Català d'Oncologia - Hospitalet
Address:
City:
Barcelona
Zip:
09908
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitari de Girona Dr. Josep Trueta - Institut Catala d'Oncologia
Address:
City:
Girona
Zip:
17007
Country:
Spain
Status:
Recruiting
Facility:
Name:
Complejo Asistencial Universitario de Leon
Address:
City:
Leon
Zip:
24001
Country:
Spain
Status:
Recruiting
Facility:
Name:
Universitary Hospital La Princesa
Address:
City:
Madrid
Zip:
28006
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinica Universidad de Navarra - Sede Madrid
Address:
City:
Madrid
Zip:
28027
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario La Paz
Address:
City:
Madrid
Zip:
28029
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Fundación Jimenez Diaz
Address:
City:
Madrid
Zip:
28040
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Virgen de la Victoria
Address:
City:
Malaga
Zip:
29010
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Clinico Universitario Santiago de Compostela
Address:
City:
Santiago de Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Virgen de Valme
Address:
City:
Seville
Zip:
41014
Country:
Spain
Status:
Recruiting
Facility:
Name:
University Hospital La Fe
Address:
City:
Valencia
Zip:
46026
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Araba
Address:
City:
Vitoria-Gasteiz
Zip:
01009
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Clinico Universitario Lozano Blesa de Zaragoza
Address:
City:
Zaragoza
Zip:
50009
Country:
Spain
Status:
Recruiting
Facility:
Name:
Changhua Christian Hospital
Address:
City:
Changhua City
Zip:
500-06
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Hualien Tzu Chi Hospital
Address:
City:
Hualien City
Zip:
970473
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Kaohsiung Medical University Hospital
Address:
City:
Kaohsiung
Zip:
807
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Kaohsiung Chang Gung Memorial Hospital
Address:
City:
Kaohsiung
Zip:
83301
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Taichung General Veterans Hosptial
Address:
City:
Taichung
Zip:
40705
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
National Cheng Kung University Hospital
Address:
City:
Tainan
Zip:
704
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
National Taiwan University Hospital
Address:
City:
Taipei
Zip:
10002
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Tri-Service General Hospital
Address:
City:
Taipei
Zip:
114
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Taipei Municipal Wanfang Hospital
Address:
City:
Taipei
Zip:
116
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Chang Gung Memorial Hospital- Linkou Branch
Address:
City:
Taoyuan
Zip:
333
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Western General Hospital
Address:
City:
Edinburgh
Zip:
EH42XU
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Royal Marsden Hospital (Sutton) - Royal Marsden NHS Foundation Trust
Address:
City:
Sutton
Zip:
SM2 5PT
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Centre for Clinical Haematology
Address:
City:
Birmingham
Zip:
B15 2GW
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Addenbrooke's Hospital
Address:
City:
Cambridge
Zip:
CB2 0QQ
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
St Bartholomew's Hospital
Address:
City:
London
Zip:
EC1A 7BE
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Guy's Hospital - Guy's & St Thomas' NHS Foundation Trust
Address:
City:
London
Zip:
SE1 9RT
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Hammersmith Hospital, Imperial College Healthcare NHS Trust
Address:
City:
London
Zip:
W12 0HS
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
The Christie NHS Foundation Trust
Address:
City:
Manchester
Zip:
M20 4BX
Country:
United Kingdom
Status:
Recruiting
Start date:
September 18, 2023
Completion date:
December 26, 2032
Lead sponsor:
Agency:
Regeneron Pharmaceuticals
Agency class:
Industry
Source:
Regeneron Pharmaceuticals
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05730036
