To hear about similar clinical trials, please enter your email below
Trial Title:
Predictors of Node Positivity in Endometrial Cancer
NCT ID:
NCT05793333
Condition:
Endometrial Cancer
Conditions: Official terms:
Endometrial Neoplasms
Conditions: Keywords:
sentinel node
endometrial cancer
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Prospective
Summary:
To investigate the role of histological and moleculr profile of endometrial cancer
patietns in predicting the risk of nodal metastases in endometrila cancer patients.
Criteria for eligibility:
Study pop:
Patietns were submitted to standard treatment modality for managing endometrial cancer.
They will receive hsyterectomy (with or without bilateral salpingo-oophorectomy) plus
sentinel ndoe mapping.
After the procedures data regarding hystologcial charactersitcs of the tumor and
molecular features will be analyzed (as routine cliical practice).
We will correlate those data with findings achieved by sentinel nodes
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Written informed consent
- Histologically confirmed endometrila cancer
- Data on molecular genomic profiling (POLE mutated, p53 abnormalities, MMRd/MSI-H,
and NSMP)
- Data on histological characteristics of the ttumor
- Execution of sentinel node mapping
- Data on sentinel node status (negative vs. positive)
Exclusion Criteria:
- Stage IVB endoemtrial cancer
- consent withdraw
Gender:
Female
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Fondazione IRCCS Istituto Nazionale dei Tumori
Address:
City:
Milano
Zip:
20148
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Giorgio Bogani
Phone:
+393803933116
Email:
giorgiobogani@yahoo.it
Contact backup:
Last name:
Valentina Chiappa, MD
Phone:
+0223901
Email:
valentina.chiappa@istitutotumori.mi.it
Start date:
January 10, 2022
Completion date:
January 1, 2025
Lead sponsor:
Agency:
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Agency class:
Other
Source:
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05793333
