A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

Trial Title: A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

NCT ID: NCT05794906

Condition: Biochemically Recurrent Prostate Cancer

Conditions: Official terms:
Prostatic Neoplasms

Conditions: Keywords:
darolutamide
high risk BCR
PSMA PET imaging

Study type: Interventional

Study phase: Phase 3

Overall status: Recruiting

Study design:

Allocation: Randomized

Intervention model: Parallel Assignment

Primary purpose: Treatment

Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Intervention:

Intervention type: Drug
Intervention name: Darolutamide (BAY1841788, Nubeqa)
Description: Coated tablet, 300 mg / tablet, oral.
Arm group label: Darolutamide+ADT

Intervention type: Other
Intervention name: Placebo matching darolutamide
Description: Coated tablet, oral
Arm group label: Placebo+ADT

Intervention type: Other
Intervention name: ADT
Description: Luteinizing hormone-releasing hormone [LHRH] agonist/antagonists
Arm group label: Darolutamide+ADT
Arm group label: Placebo+ADT

Summary: Researchers are looking for a better way to treat men at high-risk of biochemical recurrence (BCR) of prostate cancer. BCR means that in men who had prostate cancer and were treated by either surgery and/ or radiation therapy, the blood level of a specific protein called PSA rises. PSA is a marker of prostate cancer cells activity. The PSA increase means that the cancer has come back even though conventional imaging such as computed tomography (CT) scans, magnetic resonance imaging (MRI) and bone scans does not show any lesion of prostate cancer. Recently a more sensitive imaging method called prostate-specific membrane antigen [PSMA] positron emission tomography [PET]) /computed tomography [CT]) scan may identify prostate cancer lesions not detectable by conventional imaging. Men with BCR have a higher risk of their cancer spreading to other parts of the body, particularly when PSA levels raised to a certain limit within a short period of time after local therapies. Once the cancer spreads to other parts of the body, it can become even harder to treat. In men with prostate cancer, male sex hormones (also called androgens) like testosterone can help the cancer grow and spread. To reduce androgens levels in these patients, there are treatments that block androgens production in the body called androgen deprivation therapy (ADT). ADT is often used to stop prostate cancer. Another way to stop prostate cancer growth and spread is to block the action of androgen receptors on prostate cancer cells called androgen receptor inhibitors (ARIs). The new generation ARIs including darolutamide can block the action of androgens receptors and are available for the treatment of prostate cancer in addition to ADT. It is already known that men with prostate cancer benefit from these treatments. The main objective of this study is to learn if the combination of darolutamide and ADT prolongs the time that the participants live without their cancer getting worse, or to death due to any cause, compared to placebo (which is a treatment that looks like a medicine but does not have any medicine in it) and ADT given for a pre-specified duration of 24 months. To do this, the study team will measure the time from the date of treatment allocation to the finding of new cancer spread in the participants by using PSMA PET/CT, or death due to any cause. The PSMA PET/CT scans is performed using a radioactive substance called a "tracer" that specifically binds to the prostate-specific membrane antigen (PSMA) which is a protein often found in large amounts on prostate cancer cells. To avoid bias in treatment, the study participants will be randomly (by chance) allocated to one of two treatment groups. Based on the allocated treatment group, the participants will either take darolutamide plus ADT or placebo plus ADT twice daily as tablets by mouth. The study will consist of a test (screening) phase, a treatment phase and a follow-up phase. The treatment duration is pre-specified to be 24 months unless the cancer gets worse, the participants have medical problems, or they leave the study for any reason. In addition, image guided radiotherapy (IGRT) or surgery is allowed and your doctor will explain the benefits and risks of this type of therapy. During the study, the study team will: - take blood and urine samples. - measure PSA and testosterone levels in the blood samples - do physical examinations - check the participants' overall health - examine heart health using electrocardiogram (ECG) - check vital signs - check cancer status using PSMA PET/CT scans, CT, MRI and bone scans - take tumor samples (if required) - ask the participants if they have medical problems About 30 days after the participants have taken their last treatment, the study doctors and their team will check the participants' health and if their cancer worsened. The study team will continue to check this and regularly ask the participants questions about medical problems and subsequent therapies until they leave the study for any reason or until they leave the study for any reason or until the end of the study, whatever comes first.

Criteria for eligibility:
Criteria:
Inclusion Criteria: - Capable of giving signed informed consent as described which includes compliance with the requirements, restrictions listed in the informed consent form (ICF), and in this protocol. - Male ≥18 years of age at the time of signing the informed consent. - Histologically or cytologically confirmed adenocarcinoma of prostate. - Prostate cancer initially treated by: radical prostatectomy (RP) followed by adjuvant radiotherapy (ART), or salvage radiotherapy (SRT), or RP in participants who are unfit for (or refused) ART or SRT, or primary radiotherapy (RT). - High-risk biochemical recurrence (BCR), defined as Prostate-specific antigen doubling time (PSADT) <12 months calculated using the formula provided by the Sponsor, and PSA ≥0.2 ng/mL after ART or SRT post RP or after RP in participants who are unfit for ART or SRT (local or central values accepted), or PSA ≥2 ng/mL above the nadir after primary RT only (local or central values accepted). - Participants must undergo prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) within the 42-day Screening period using either 18F-DCFPyL (piflufolastat F 18) or 68Ga-PSMA-11 which will be assessed by blinded independent central review (BICR) to identify at least one PSMA PET/CT lesion of prostate cancer. - Serum testosterone ≥150 ng/dL (5.2 nmol/L) (local assessment is allowed whenever central assessment cannot be done). - Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1. - Blood counts at screening: Hemoglobin ≥9.0 g/dL (participant must not have received blood transfusion within 7 days prior to sample being taken); Absolute neutrophil count (ANC) ≥1.5x10^9/L (participant must not have received any growth factor within 4 weeks prior to sample being taken); Platelet count ≥100x10^9/L. - Screening values of: Alanine aminotransferase (ALT) ≤1.5 x upper limit of normal (ULN); Aspartate aminotransferase (AST) ≤1.5 x ULN; Total bilirubin (TBL) ≤1.5 ULN, (except participants with a diagnosis of Gilbert's disease); Estimated glomerular filtration rate (eGFR) >40 ml/min/1.73 m^2 calculated by the CKD-EPI formula. - Sexually active male participants must agree to use contraception as detailed in the protocol during the Treatment period and for at least 1 week after the last dose of study treatment, and refrain from donating sperm during this period. Exclusion Criteria: - Pathological finding consistent with small cell, ductal or ≥50 % component of neuroendocrine carcinoma of the prostate. - History of bilateral orchiectomy. - Metastases or recurrent /new malignant lesions in prostate gland/bed seminal vesicles, lymph nodes below the CIA bifurcation on conventional imaging (CI) as assessed by BICR during screening. - Brain metastasis on PSMA PET /CT by BICR at screening. - High-risk BCR after primary radiotherapy with new loco-regional lesions on screening PSMA PET/CT who are eligible for curative salvage prostatectomy. Note: Participants treated with curative salvage prostatectomy after primary RT who meet the PSA criteria (inclusion criteria 5) may be considered for the study. - Prior treatment with second generation (e.g. enzalutamide, apalutamide) androgen receptor inhibitors (ARIs) and CYP 17 inhibitors (e.g., abiraterone) within 18 months prior to signing of the ICF. - Prior treatments with PSMA-radiotherapeutics within 12 months prior to randomization. - Prior radiotherapy (including image-guided radiotherapy) as primary, adjuvant or salvage treatment completed within 8 weeks prior to signing of the ICF. - Any prior malignancy (other than adequately treated basal cell or squamous cell skin cancer, superficial bladder cancer, or any other cancer in situ currently in complete remission) within 5 years. - History of pelvic radiotherapy for other malignancy.

Gender: Male

Minimum age: 18 Years

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: City of Hope - Phoenix Cancer Center

Address:
City: Goodyear
Zip: 85338
Country: United States

Status: Not yet recruiting

Facility:
Name: Mayo Clinic Hospital

Address:
City: Phoenix
Zip: 85054
Country: United States

Status: Recruiting

Facility:
Name: Arizona Institute of Urology

Address:
City: Tucson
Zip: 85704
Country: United States

Status: Withdrawn

Facility:
Name: City of Hope National Medical Center

Address:
City: Duarte
Zip: 91010
Country: United States

Status: Recruiting

Facility:
Name: University of Southern California

Address:
City: Los Angeles
Zip: 90033
Country: United States

Status: Recruiting

Facility:
Name: Tower Urology, Inc

Address:
City: Los Angeles
Zip: 90048
Country: United States

Status: Terminated

Facility:
Name: University of California, Los Angeles

Address:
City: Los Angeles
Zip: 90095
Country: United States

Status: Not yet recruiting

Facility:
Name: University of California Irvine Medical Center

Address:
City: Orange
Zip: 92868-3201
Country: United States

Status: Withdrawn

Facility:
Name: UCSF Med Center Helen Diller Family Comp Cancer Center

Address:
City: San Francisco
Zip: 94143
Country: United States

Status: Not yet recruiting

Facility:
Name: Colorado Urology (Colorado Clinical Research)

Address:
City: Lakewood
Zip: 80228
Country: United States

Status: Recruiting

Facility:
Name: Clermont Oncology Center

Address:
City: Clermont
Zip: 34711
Country: United States

Status: Withdrawn

Facility:
Name: University of Florida - Jacksonville

Address:
City: Jacksonville
Zip: 32209
Country: United States

Status: Withdrawn

Facility:
Name: Mid Florida Cancer Centers

Address:
City: Orange City
Zip: 32763-8316
Country: United States

Status: Withdrawn

Facility:
Name: Northwestern University Feinberg School of Medicine - Department of Urology

Address:
City: Chicago
Zip: 60611
Country: United States

Status: Recruiting

Facility:
Name: Jesse Brown VA Medical Center

Address:
City: Chicago
Zip: 60612
Country: United States

Status: Withdrawn

Facility:
Name: Comprehensive Cancer Center

Address:
City: Chicago
Zip: 60637
Country: United States

Status: Withdrawn

Facility:
Name: Urology of Indiana, LLC

Address:
City: Greenwood
Zip: 46143
Country: United States

Status: Withdrawn

Facility:
Name: First Urology PSC

Address:
City: Jeffersonville
Zip: 47130
Country: United States

Status: Withdrawn

Facility:
Name: University of Kansas

Address:
City: Kansas City
Zip: 66160
Country: United States

Status: Recruiting

Facility:
Name: Chesapeake Urology Associates

Address:
City: Baltimore
Zip: 21204
Country: United States

Status: Recruiting

Facility:
Name: Johns Hopkins Univ School Med|Sidney Kimmel Comp Cancer Cntr

Address:
City: Baltimore
Zip: 21231
Country: United States

Status: Recruiting

Facility:
Name: Dana-Farber Cancer Institute

Address:
City: Boston
Zip: 02215
Country: United States

Status: Recruiting

Facility:
Name: UMass Memorial Medical Center - University Campus

Address:
City: Worcester
Zip: 01655-0002
Country: United States

Status: Withdrawn

Facility:
Name: Barbara Ann Karmanos Cancer Institute - Detroit

Address:
City: Detroit
Zip: 48201
Country: United States

Status: Recruiting

Facility:
Name: Michigan Institute of Urology, PC

Address:
City: Troy
Zip: 48084
Country: United States

Status: Not yet recruiting

Facility:
Name: University of Minnesota Medical Center

Address:
City: Minneapolis
Zip: 55455
Country: United States

Status: Recruiting

Facility:
Name: Washington University School of Medicine - Center for Advanced Medicine (CAM)

Address:
City: Saint Louis
Zip: 63110-1032
Country: United States

Status: Not yet recruiting

Facility:
Name: Urology Cancer Center, PC

Address:
City: Omaha
Zip: 68130
Country: United States

Status: Recruiting

Facility:
Name: New Jersey Urology (NJU)

Address:
City: Saddle Brook
Zip: 07663-5227
Country: United States

Status: Withdrawn

Facility:
Name: New Jersey Urology, LLC

Address:
City: Voorhees
Zip: 08043
Country: United States

Status: Not yet recruiting

Facility:
Name: NYU Langone Health

Address:
City: Mineola
Zip: 11501
Country: United States

Status: Completed

Facility:
Name: Icahn School of Medicine at Mount Sinai (ISMMS) - The Mount Sinai Hospital (MSH)

Address:
City: New York
Zip: 10029-6500
Country: United States

Status: Not yet recruiting

Facility:
Name: Associated Medical Professionals of NY, PLLC

Address:
City: Syracuse
Zip: 13210
Country: United States

Status: Withdrawn

Facility:
Name: White Plains Hospital

Address:
City: White Plains
Zip: 10601
Country: United States

Status: Not yet recruiting

Facility:
Name: Alliance Urology Specialists

Address:
City: Greensboro
Zip: 27403
Country: United States

Status: Recruiting

Facility:
Name: Wake Forest Baptist Health

Address:
City: Winston-Salem
Zip: 27157
Country: United States

Status: Withdrawn

Facility:
Name: The Urology Group

Address:
City: Cincinnati
Zip: 45212
Country: United States

Status: Not yet recruiting

Facility:
Name: Ohio State University Wexner Medical Center

Address:
City: Columbus
Zip: 43210
Country: United States

Status: Withdrawn

Facility:
Name: MidLantic Urology - Bala Cynwyd

Address:
City: Bala-Cynwyd
Zip: 19004
Country: United States

Status: Withdrawn

Facility:
Name: Urological Associates of Lancaster

Address:
City: Lancaster
Zip: 17604
Country: United States

Status: Withdrawn

Facility:
Name: Allegheny General Hospital

Address:
City: Pittsburgh
Zip: 15212
Country: United States

Status: Recruiting

Facility:
Name: University of Pittsburgh

Address:
City: Pittsburgh
Zip: 15232
Country: United States

Status: Withdrawn

Facility:
Name: VA Pittsburgh Healthcare System

Address:
City: Pittsburgh
Zip: 15240
Country: United States

Status: Withdrawn

Facility:
Name: Bon Secours St. Francis Hospital

Address:
City: Greenville
Zip: 29607
Country: United States

Status: Withdrawn

Facility:
Name: Carolina Urological Research Center

Address:
City: Myrtle Beach
Zip: 29579
Country: United States

Status: Recruiting

Facility:
Name: Urology Austin, PLLC (an affiliate of Urology America)

Address:
City: Austin
Zip: 78745
Country: United States

Status: Withdrawn

Facility:
Name: University of Texas Southwestern Medical Center-Harold C. Simmons Comprehensive Cancer Center

Address:
City: Dallas
Zip: 75235
Country: United States

Status: Not yet recruiting

Facility:
Name: University of Texas MD Anderson Cancer Center

Address:
City: Houston
Zip: 77030
Country: United States

Status: Recruiting

Facility:
Name: Urology San Antonio, PA dba USA Clinical Trials

Address:
City: San Antonio
Zip: 78229
Country: United States

Status: Recruiting

Facility:
Name: The Urology Place

Address:
City: San Antonio
Zip: 78240
Country: United States

Status: Recruiting

Facility:
Name: Spokane Urology PS

Address:
City: Spokane
Zip: 99202
Country: United States

Status: Withdrawn

Facility:
Name: Blacktown Hospital

Address:
City: Blacktown
Zip: 2148
Country: Australia

Status: Not yet recruiting

Facility:
Name: University of New South Wales (UNSW) - Liverpool Hospital - Liverpool Cancer Therapy Centre

Address:
City: Liverpool
Zip: 2170
Country: Australia

Status: Not yet recruiting

Facility:
Name: Macquarie University Hospital

Address:
City: Macquarie University
Zip: 2109
Country: Australia

Status: Withdrawn

Facility:
Name: GenesisCare Newcastle

Address:
City: Newcastle
Zip: 2290
Country: Australia

Status: Withdrawn

Facility:
Name: Port Macquarie Base Hospital

Address:
City: Port Macquarie
Zip: 2444
Country: Australia

Status: Withdrawn

Facility:
Name: Chris O'Brien Lifehouse

Address:
City: Randwick
Zip: 2031
Country: Australia

Status: Recruiting

Facility:
Name: St Vincents Hospital Sydney

Address:
City: Sydney
Zip: 2010
Country: Australia

Status: Withdrawn

Facility:
Name: Sydney Adventist Hospital

Address:
City: Wahroonga
Zip: 2076
Country: Australia

Status: Recruiting

Facility:
Name: Westmead Hospital

Address:
City: Westmead
Zip: 2145
Country: Australia

Status: Withdrawn

Facility:
Name: Royal Brisbane & Women's Hospital

Address:
City: Brisbane
Zip: 4029
Country: Australia

Status: Not yet recruiting

Facility:
Name: Bundaberg Hospital, Genesis Cancer Care - Bundaberg

Address:
City: Bundaberg
Zip: 4670
Country: Australia

Status: Withdrawn

Facility:
Name: Wide Bay Hospital and Health Service - Hervey Bay Hospital

Address:
City: Pialba
Zip: 4655
Country: Australia

Status: Withdrawn

Facility:
Name: Tasman Health Care

Address:
City: Southport
Zip: 4215
Country: Australia

Status: Withdrawn

Facility:
Name: Royal Adelaide Hospital

Address:
City: Adelaide
Zip: 5000
Country: Australia

Status: Not yet recruiting

Facility:
Name: Eastern Clinical Research Unit - Box Hill

Address:
City: Box Hill
Zip: 3128
Country: Australia

Status: Recruiting

Facility:
Name: Northern Hospital

Address:
City: Epping
Zip: 3076
Country: Australia

Status: Not yet recruiting

Facility:
Name: Barwon Health

Address:
City: Geelong
Zip: 3220
Country: Australia

Status: Not yet recruiting

Facility:
Name: Austin Health

Address:
City: Heidelberg
Zip: 3084
Country: Australia

Status: Recruiting

Facility:
Name: Cabrini Malvern

Address:
City: Malvern
Zip: 3144
Country: Australia

Status: Not yet recruiting

Facility:
Name: Western Urology

Address:
City: Maribyrnong
Zip: 3032
Country: Australia

Status: Recruiting

Facility:
Name: Royal Melbourne Hospital

Address:
City: Parkville
Zip: 3050
Country: Australia

Status: Not yet recruiting

Facility:
Name: Epworth HealthCare

Address:
City: Richmond
Zip: 3121
Country: Australia

Status: Recruiting

Facility:
Name: Sir Charles Gairdner Hospital

Address:
City: Nedlands
Zip: 6009
Country: Australia

Status: Not yet recruiting

Facility:
Name: Prince of Wales Hospital NSW

Address:
City: Randwick
Zip: 2031
Country: Australia

Status: Not yet recruiting

Facility:
Name: Ordensklinikum Linz GmbH Elisabethinen

Address:
City: Linz
Zip: 4020
Country: Austria

Status: Recruiting

Facility:
Name: Medizinische Universität Innsbruck

Address:
City: Innsbruck
Zip: 6020
Country: Austria

Status: Recruiting

Facility:
Name: Krankenhaus der Barmherzigen Brüder

Address:
City: Vienna
Zip: 1020
Country: Austria

Status: Not yet recruiting

Facility:
Name: Medizinische Universitaet Graz - Klinische Abteilung für Onkologie - Innere Medizin

Address:
City: Graz
Zip: 8036
Country: Austria

Status: Not yet recruiting

Facility:
Name: Uniklinikum Salzburg - Landeskrankenhaus

Address:
City: Salzburg
Zip: 5020
Country: Austria

Status: Recruiting

Facility:
Name: Medizinische Universität Wien Universitätsklinik f. Innere Medizin I Klinische Abteilung für Onkologie

Address:
City: Wien
Zip: 1090
Country: Austria

Status: Recruiting

Facility:
Name: Institut Jules Bordet/Jules Bordet Instituut

Address:
City: Bruxelles
Zip: 1070
Country: Belgium

Status: Withdrawn

Facility:
Name: Maria Middelares General Hospital | Medical Oncology Department

Address:
City: Gent
Zip: 9000
Country: Belgium

Status: Not yet recruiting

Facility:
Name: UZ Gent - department Urology

Address:
City: Gent
Zip: 9000
Country: Belgium

Status: Not yet recruiting

Facility:
Name: Jessa Hospital | Campus Virga Jesse - Data Management Oncology and Hematology Department

Address:
City: Hasselt
Zip: 3500
Country: Belgium

Status: Not yet recruiting

Facility:
Name: AZ Groeninge Campus Kennedylaan - Urology

Address:
City: Kortrijk
Zip: 8500
Country: Belgium

Status: Not yet recruiting

Facility:
Name: Hopital de La Louvière - Site Jolimont - Oncology department

Address:
City: La Louvière
Zip: 7100
Country: Belgium

Status: Not yet recruiting

Facility:
Name: Universitair Ziekenhuis Leuven | Gasthuisberg Campus - Urology Department

Address:
City: Leuven
Zip: 3000
Country: Belgium

Status: Not yet recruiting

Facility:
Name: Hospital São Rafael

Address:
City: Salvador
Zip: 41253-190
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Assistência Multidisciplinar em Oncologia (AMO)

Address:
City: Salvador
Zip: 41950-640
Country: Brazil

Status: Recruiting

Facility:
Name: Oncocentro - Fortaleza

Address:
City: Fortaleza
Zip: 60135-237
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Hospital Evangélico de Cachoeiro de Itapemirim

Address:
City: Vitória
Zip: 29047-660
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Liga Paranaense de Combate ao Cancer-Hosp Erasto Gaertner

Address:
City: Curitiba
Zip: 81520-060
Country: Brazil

Status: Recruiting

Facility:
Name: Real Hospital Português

Address:
City: Recife
Zip: 50070-160
Country: Brazil

Status: Withdrawn

Facility:
Name: Liga Norte Riograndense Contra o Cancer | Centro de Pesquisa Clínica

Address:
City: Natal
Zip: 59040-000
Country: Brazil

Status: Recruiting

Facility:
Name: Hospital Moinhos de Vento-Centro Clínico

Address:
City: Porto Alegre
Zip: 90035-001
Country: Brazil

Status: Recruiting

Facility:
Name: Hospital Mae de Deus

Address:
City: Porto Alegre
Zip: 90850-170
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Instituto D'Or Pesquisa e Ensino (IDOR) (D'Or Institute for Research & Education) - Rio de Janeiro

Address:
City: Rio de Janeiro
Zip: 22281-100
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Faculdade de Medicina do ABC

Address:
City: Santo André
Zip: 09060-650
Country: Brazil

Status: Recruiting

Facility:
Name: Instituto do Cancer do Estado de Sao Paulo

Address:
City: São Paulo
Zip: 01246-000
Country: Brazil

Status: Recruiting

Facility:
Name: Real e Benemérita Associação Portuguesa de Beneficência

Address:
City: São Paulo
Zip: 01323-001
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Inst. de Assistência Médica ao Sérvidor Público Estadual

Address:
City: São Paulo
Zip: 04039-004
Country: Brazil

Status: Recruiting

Facility:
Name: Hospital das Clínicas da Universidade de Campinas - UNICAMP

Address:
City: São Paulo
Zip: 13083-881
Country: Brazil

Status: Not yet recruiting

Facility:
Name: NAIC - Instituto do Cancer

Address:
City: Bauru
Zip: 17033-490
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Hospital Sirio Libanês - Hospital Base de Brasilia

Address:
City: Brasilia
Zip: 70200-730
Country: Brazil

Status: Withdrawn

Facility:
Name: Universidade Estadual do Rio de Janeiro

Address:
City: Rio de Janeiro
Zip: TBC
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Hospital Alemao Oswaldo Cruz

Address:
City: Sao Paulo
Zip: 01321-001
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Hospital Sirio Libanes

Address:
City: Sao Paulo
Zip: 01409-000
Country: Brazil

Status: Recruiting

Facility:
Name: Hospital do Cancer de Sao Paulo - A. C. Camargo

Address:
City: Sao Paulo
Zip: 01509-900
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Hospital Israelita Albert Einstein | Morumbi - Clinical Research Department

Address:
City: Sao Paulo
Zip: 05651-901
Country: Brazil

Status: Not yet recruiting

Facility:
Name: Prostate Cancer Centre

Address:
City: Calgary
Zip: T2V 1P9
Country: Canada

Status: Recruiting

Facility:
Name: Vancouver Prostate Centre

Address:
City: Vancouver
Zip: V5Z 1M9
Country: Canada

Status: Not yet recruiting

Facility:
Name: BC Cancer - Victoria

Address:
City: Victoria
Zip: V8R 6V5
Country: Canada

Status: Recruiting

Facility:
Name: Nova Scotia Health Authority

Address:
City: Halifax
Zip: B3H 2Y9
Country: Canada

Status: Recruiting

Facility:
Name: St. Joseph's Healthcare - Hamilton

Address:
City: Hamilton
Zip: L8N 4A6
Country: Canada

Status: Recruiting

Facility:
Name: London Health Sciences Centre (LHSC) - London Regional Cancer Program (LRCP)

Address:
City: London
Zip: N6A 5W9
Country: Canada

Status: Not yet recruiting

Facility:
Name: Princess Margaret Cancer Centre - UHN

Address:
City: Toronto
Zip: M5G 2M9
Country: Canada

Status: Not yet recruiting

Facility:
Name: CISSS de l'Outaouais - Hopital de Gatineau - Centre de cancerolgie

Address:
City: Gatineau
Zip: J8P 7H2
Country: Canada

Status: Not yet recruiting

Facility:
Name: Urology South Shore Research - Research Department

Address:
City: Greenfield Park
Zip: J4V 2H3
Country: Canada

Status: Not yet recruiting

Facility:
Name: Hopital Maisonneuve-Rosemont

Address:
City: Montreal
Zip: H1T 2M4
Country: Canada

Status: Not yet recruiting

Facility:
Name: Sir Mortimer B. Davis Jewish General Hospital - Radiation Oncology

Address:
City: Montreal
Zip: H3T 1E2
Country: Canada

Status: Recruiting

Facility:
Name: Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-Centre-du-Quebec - Radio-oncologie

Address:
City: Trois-rivieres
Zip: G8Z 3R9
Country: Canada

Status: Recruiting

Facility:
Name: BC Cancer - Abbotsford Centre

Address:
City: Abbotsford
Zip: V2S 0C2
Country: Canada

Status: Recruiting

Facility:
Name: Kaye Edmonton Clinic - Dianne and Irving Kipnes Urology Centre

Address:
City: Edmonton
Zip: T6G 1Z1
Country: Canada

Status: Not yet recruiting

Facility:
Name: Hopital Hotel-Dieu de Levis

Address:
City: Quebec
Zip: G6V 3Z1
Country: Canada

Status: Recruiting

Facility:
Name: Centre Hospitalier Universitaire de Sherbrooke (CHUS) - Hopital Fleurimont

Address:
City: Sherbrooke
Zip: J1H 5N4
Country: Canada

Status: Recruiting

Facility:
Name: Zhongnan hospital ,Wuhan University

Address:
City: Wuhan
Zip: 430071
Country: China

Status: Recruiting

Facility:
Name: Hunan Cancer Hospital

Address:
City: Changsha
Zip: 410013
Country: China

Status: Not yet recruiting

Facility:
Name: The Affiliated Hospital of Inner Mongolia Medical University

Address:
City: Hohehot
Zip: 10050
Country: China

Status: Not yet recruiting

Facility:
Name: Nanjing First Hospital

Address:
City: Nanjing
Zip: 210006
Country: China

Status: Recruiting

Facility:
Name: Fudan University Shanghai Cancer Center

Address:
City: Shanghai
Zip: 200000
Country: China

Status: Recruiting

Facility:
Name: West China Hospital,Sichuan University

Address:
City: Chengdu
Zip: 610041
Country: China

Status: Recruiting

Facility:
Name: The 1st Affiliated Hospital of Zhejiang University

Address:
City: Hangzhou
Zip: 310003
Country: China

Status: Recruiting

Facility:
Name: Peking University First Hospital

Address:
City: Beijing
Zip: 100034
Country: China

Status: Not yet recruiting

Facility:
Name: Peking Union Medical College Hospital (PUMCH) - East Location

Address:
City: Beijing
Zip: 100730
Country: China

Status: Recruiting

Facility:
Name: Jiangsu Provincial People's Hospital - The First Affiliated Hospital of Nanjing Medical University

Address:
City: Nanjing
Zip: 210029
Country: China

Status: Recruiting

Facility:
Name: Ruijin Hosp. Shanghai Jiaotong Univ.School of Medicine

Address:
City: Shanghai
Zip: 200025
Country: China

Status: Withdrawn

Facility:
Name: Tianjin Cancer Hospital, Airport Hospital

Address:
City: Tianjin
Zip: 300308
Country: China

Status: Recruiting

Facility:
Name: Fakultni nemocnice u Sv. Anny, Onkologicko-chirurgicke oddeleni

Address:
City: Brno
Zip: 602 00
Country: Czechia

Status: Recruiting

Facility:
Name: Masarykova Univerzita - Masarykuv Onkologicky Ustav (MOU) - Klinika Komplexni Onkologicke Pece (KKOP)

Address:
City: Brno
Zip: 602 00
Country: Czechia

Status: Recruiting

Facility:
Name: Multiscan s.r.o., Department: Ambulance klinické onkologie Nemocnice Horovice

Address:
City: Horovice
Zip: 26801
Country: Czechia

Status: Withdrawn

Facility:
Name: Fakultni Nemocnice Olomouc (FNOL) - Onkologicka Klinika

Address:
City: Olomouc
Zip: 779 00
Country: Czechia

Status: Recruiting

Facility:
Name: Thomayerova Nemocnice (TN) (Thomayers Hospital) - Onkologicka Klinika 1. LF UK A TN

Address:
City: Prague
Zip: 140 59
Country: Czechia

Status: Not yet recruiting

Facility:
Name: Fakultni nemocnice v Motole, Onkologicka klinika 2. LF UK a FN Motol

Address:
City: Prague
Zip: 15006
Country: Czechia

Status: Not yet recruiting

Facility:
Name: Vseobecna fakultni nemocnice - Urologicka klinika, Praha

Address:
City: Praha 2
Zip: 128 08
Country: Czechia

Status: Not yet recruiting

Facility:
Name: Aalborg University Hospital

Address:
City: Aalborg
Zip: 9000
Country: Denmark

Status: Recruiting

Facility:
Name: Aarhus Universitetshospital

Address:
City: Aarhus N
Zip: 8200
Country: Denmark

Status: Recruiting

Facility:
Name: Rigshospitalet - Kræftbehandling

Address:
City: København Ø
Zip: 2100
Country: Denmark

Status: Recruiting

Facility:
Name: Sjællands University hospital Næstved

Address:
City: Næstved
Zip: 4700
Country: Denmark

Status: Not yet recruiting

Facility:
Name: Docrates Klinikka

Address:
City: Helsinki
Zip: 00180
Country: Finland

Status: Withdrawn

Facility:
Name: HUS, Meilahden sairaala

Address:
City: Helsinki
Zip: FIN-00260
Country: Finland

Status: Recruiting

Facility:
Name: Oulun yliopistollinen sairaala

Address:
City: Oulu
Zip: 90220
Country: Finland

Status: Recruiting

Facility:
Name: Tampereen yliopistollinen sairaala

Address:
City: Tampere
Zip: 33520
Country: Finland

Status: Recruiting

Facility:
Name: Turun yliopistollinen keskussairaala

Address:
City: Turku
Zip: 20520
Country: Finland

Status: Recruiting

Facility:
Name: Centre d'oncologie du Pays Basque

Address:
City: Bayonne
Zip: 64100
Country: France

Status: Not yet recruiting

Facility:
Name: Centre Hospitalier Regional et Universitaire (CHRU) de Besancon - L'Hopital Jean Minjoz

Address:
City: Besancon
Zip: 25000
Country: France

Status: Not yet recruiting

Facility:
Name: Hôpital Pellegrin - Bordeaux

Address:
City: BORDEAUX cedex
Zip: 33076
Country: France

Status: Recruiting

Facility:
Name: Centre Hospitalier Regional Universitaire (CHRU) Brest - Hopital de la Cavale Blanche

Address:
City: Brest
Zip: 29609
Country: France

Status: Not yet recruiting

Facility:
Name: Centre Hospitalier Universitaire de Clermont Ferrand - Gabriel Montpied

Address:
City: Clermont Ferrand
Zip: 63003
Country: France

Status: Recruiting

Facility:
Name: Assistance Publique-Hopitaux de Paris (AP-HP) - Hopitaux Universitaires Henri Mondor (Hopital Henri-Mondor)

Address:
City: Creteil
Zip: 94000
Country: France

Status: Not yet recruiting

Facility:
Name: Institut de Cancérologie de Bourgogne

Address:
City: Dijon
Zip: 21000
Country: France

Status: Not yet recruiting

Facility:
Name: Centre Georges Francois Leclerc Dijon

Address:
City: Dijon
Zip: 21079
Country: France

Status: Not yet recruiting

Facility:
Name: CHU GRENOBLE - Hopital Michallon

Address:
City: GRENOBLE Cedex 09
Zip: 38043
Country: France

Status: Recruiting

Facility:
Name: Centre Bourgogne - Hôpital Privé Le Bois

Address:
City: Lille
Zip: 59000
Country: France

Status: Not yet recruiting

Facility:
Name: Hôpital Claude Huriez - Lille

Address:
City: Lille
Zip: 59037
Country: France

Status: Recruiting

Facility:
Name: UNICANCER - Centre Leon-Berard (CLB)

Address:
City: Lyon
Zip: 69008
Country: France

Status: Not yet recruiting

Facility:
Name: Hôpital de la Timone - Marseille

Address:
City: Marseille
Zip: 13005
Country: France

Status: Not yet recruiting

Facility:
Name: Clinique Clementville

Address:
City: Montpellier
Zip: 34070
Country: France

Status: Recruiting

Facility:
Name: Institut Curie - Ulm - Paris

Address:
City: PARIS cedex 5
Zip: 75248
Country: France

Status: Not yet recruiting

Facility:
Name: Hopital Bichat - Paris

Address:
City: Paris
Zip: 75018
Country: France

Status: Withdrawn

Facility:
Name: Centre Hospitalier Lyon Sud

Address:
City: Pierre Benite
Zip: 69495
Country: France

Status: Recruiting

Facility:
Name: Institut de Cancérologie Jean Godinot

Address:
City: Reims
Zip: 51726
Country: France

Status: Not yet recruiting

Facility:
Name: Hôpital Pontchaillou

Address:
City: Rennes Cedex
Zip: 35033
Country: France

Status: Recruiting

Facility:
Name: Institue Curie - Saint-Cloud

Address:
City: Saint-Cloud
Zip: 92210
Country: France

Status: Not yet recruiting

Facility:
Name: Institut de Cancérologie de l'Ouest - Saint Herblain

Address:
City: Saint-Herblain
Zip: 44800
Country: France

Status: Recruiting

Facility:
Name: ICANS - Institut de Cancérologie de Strasbourg Europe

Address:
City: Strasbourg
Zip: 67033
Country: France

Status: Recruiting

Facility:
Name: Institut Claudius Regaud - iUCT Oncopole

Address:
City: Toulouse Cedex 9
Zip: 31059
Country: France

Status: Not yet recruiting

Facility:
Name: Hôpital Bretonneau

Address:
City: Tours
Zip: 37044
Country: France

Status: Not yet recruiting

Facility:
Name: Institut de Cancérologie de Lorraine - Alexis Vautrin

Address:
City: Vandoeuvre-les-Nancy
Zip: 54519
Country: France

Status: Recruiting

Facility:
Name: Institut Gustave Roussy - Département de Médecine Oncologique

Address:
City: Villejuif Cedex
Zip: 94805
Country: France

Status: Recruiting

Facility:
Name: Klinikum Mannheim GmbH

Address:
City: Mannheim
Zip: 68135
Country: Germany

Status: Not yet recruiting

Facility:
Name: Studienpraxis Urologie

Address:
City: Nürtingen
Zip: 72622
Country: Germany

Status: Not yet recruiting

Facility:
Name: Klinikum rechts der Isar

Address:
City: München
Zip: 81675
Country: Germany

Status: Not yet recruiting

Facility:
Name: Klinikum der Universität Würzburg

Address:
City: Wurzburg
Zip: 97080
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitätsklinikum der Johann Wolfgang Goethe Universität

Address:
City: Frankfurt
Zip: 60590
Country: Germany

Status: Not yet recruiting

Facility:
Name: Städtisches Klinikum Braunschweig gGmbH

Address:
City: Braunschweig
Zip: 38126
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitätsmedizin der Georg-August-Universität Göttingen

Address:
City: Göttingen
Zip: 37075
Country: Germany

Status: Not yet recruiting

Facility:
Name: Urologicum Duisburg

Address:
City: Duisburg
Zip: 47169
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitätsklinikum Köln

Address:
City: Köln
Zip: 50937
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitaetsklinikum Muenster

Address:
City: Münster
Zip: 48149
Country: Germany

Status: Not yet recruiting

Facility:
Name: Marienhospital Herne Universitätsklinik

Address:
City: Herne
Zip: 44625
Country: Germany

Status: Not yet recruiting

Facility:
Name: Medizinische Fakultät der Otto-von-Guericke Universität

Address:
City: Magdeburg
Zip: 39120
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden

Address:
City: Dresden
Zip: 1307
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitätsklinikum Aachen / Klinik und Poliklinik für Urologie und Kinderurologie

Address:
City: Aachen
Zip: 52074
Country: Germany

Status: Not yet recruiting

Facility:
Name: Marien-Krankenhaus Bergisch Gladbach

Address:
City: Bergisch Gladbach
Zip: 51465
Country: Germany

Status: Not yet recruiting

Facility:
Name: Vivantes Klinikum Am Urban

Address:
City: Berlin
Zip: 10967
Country: Germany

Status: Not yet recruiting

Facility:
Name: Charité Campus Benjamin Franklin (CBF)

Address:
City: Berlin
Zip: 12203
Country: Germany

Status: Withdrawn

Facility:
Name: Martini-Klinik Hamburg

Address:
City: Hamburg
Zip: 20246
Country: Germany

Status: Recruiting

Facility:
Name: Universitaetsklinikum Jena - Klinik fuer Urologie

Address:
City: Jena
Zip: 7747
Country: Germany

Status: Not yet recruiting

Facility:
Name: Universitätsklinikum Schleswig-Holstein/ Klinik für Urologie

Address:
City: Kiel
Zip: 24105
Country: Germany

Status: Not yet recruiting

Facility:
Name: Johannes Gutenberg-Universität Mainz - Urologie

Address:
City: Mainz
Zip: 55131
Country: Germany

Status: Not yet recruiting

Facility:
Name: Klinikum Stuttgart / Klinik für Urologie und Transplantationschirurgie

Address:
City: Stuttgart
Zip: 70174
Country: Germany

Status: Not yet recruiting

Facility:
Name: Urologische Gemeinschaftspraxis Wesel

Address:
City: Wesel
Zip: 46483
Country: Germany

Status: Not yet recruiting

Facility:
Name: Semmelweis Egyetem, Altalanos Orvostudomanyi Kar, Urologiai Klinika

Address:
City: Budapest
Zip: 1082
Country: Hungary

Status: Not yet recruiting

Facility:
Name: Orszagos Onkologiai Intezet

Address:
City: Budapest
Zip: 1122
Country: Hungary

Status: Not yet recruiting

Facility:
Name: Budapesti Uzsoki Utcai Korhaz

Address:
City: Budapest
Zip: 1145
Country: Hungary

Status: Recruiting

Facility:
Name: Budapesti Jahn Ferenc Del-pesti Korhaz es Rendelointezet

Address:
City: Budapest
Zip: 1204
Country: Hungary

Status: Not yet recruiting

Facility:
Name: Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz

Address:
City: Gyor
Zip: 9024
Country: Hungary

Status: Not yet recruiting

Facility:
Name: Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz Nyiregyhazi Josa Andras Tagkorhaz

Address:
City: Nyiregyhaza
Zip: H-4400
Country: Hungary

Status: Not yet recruiting

Facility:
Name: Rambam Health Corporation

Address:
City: Haifa
Zip: 3109601
Country: Israel

Status: Withdrawn

Facility:
Name: Hadassah Hebrew University Hospital Ein Kerem

Address:
City: Jerusalem
Zip: 9112001
Country: Israel

Status: Withdrawn

Facility:
Name: Shaare Zedek Medical Center

Address:
City: Jerusalem
Zip: 9372212
Country: Israel

Status: Withdrawn

Facility:
Name: Rabin Medical Center | Beilinson Hospital - Internal Medicine C Department

Address:
City: Petah Tikva
Zip: 4941492
Country: Israel

Status: Withdrawn

Facility:
Name: Sheba Medical Center

Address:
City: Tel Hashomer
Zip: 52621
Country: Israel

Status: Withdrawn

Facility:
Name: Sourasky Medical Center

Address:
City: Tel-Aviv
Zip: 64239
Country: Israel

Status: Withdrawn

Facility:
Name: IRCCS Istituto Nazionale Tumori Fondazione Pascale - S. C. Oncologia Clinica Sperimentale Uro-Ginecologica

Address:
City: Napoli
Zip: 80131
Country: Italy

Status: Recruiting

Facility:
Name: Azienda Unita Sanitaria Locale Di Bologna_Ospedale Bellaria - Oncologia Medica

Address:
City: Bologna
Zip: 40139
Country: Italy

Status: Not yet recruiting

Facility:
Name: Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - Urologia

Address:
City: Bologna
Zip: 40138
Country: Italy

Status: Recruiting

Facility:
Name: A.O.U. di Modena - Policlinico

Address:
City: Modena
Zip: 41124
Country: Italy

Status: Recruiting

Facility:
Name: Azienda USL IRCCS di Reggio Emilia_Arcispedale Santa Maria Nuova - S.C. Oncologia

Address:
City: Reggio Emilia
Zip: 42123
Country: Italy

Status: Not yet recruiting

Facility:
Name: Centro di Riferimento Oncologico di Aviano - Oncologia Radioterapica

Address:
City: Aviano (PN)
Zip: 33081
Country: Italy

Status: Not yet recruiting

Facility:
Name: I.F.O. Istituti Fisioterapici Ospitalieri_Ospedale Regina Elena - Urologia

Address:
City: Roma
Zip: 00128
Country: Italy

Status: Recruiting

Facility:
Name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Degenza di Radioterapia Oncologica

Address:
City: Roma
Zip: 00168
Country: Italy

Status: Not yet recruiting

Facility:
Name: IRCCS Ist Nazionale Tumori GE - Oncologia Medica

Address:
City: Genova
Zip: 16132
Country: Italy

Status: Recruiting

Facility:
Name: Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII - Oncologia

Address:
City: Bergamo
Zip: 24127
Country: Italy

Status: Recruiting

Facility:
Name: Ospedale San Raffaele s.r.l - Urologia

Address:
City: Milano
Zip: 20132
Country: Italy

Status: Recruiting

Facility:
Name: Fondazione IRCCS Istituto Nazionale dei Tumori

Address:
City: Milano
Zip: 20133
Country: Italy

Status: Withdrawn

Facility:
Name: Humanitas Mirasole S.p.A. - Oncologia Medica ed Ematologia

Address:
City: Rozzano
Zip: 20089
Country: Italy

Status: Not yet recruiting

Facility:
Name: A.O.U. Città della Salute e della Scienza di Torino - Urologia U

Address:
City: Torino
Zip: 10126
Country: Italy

Status: Recruiting

Facility:
Name: A.O.U. Consorziale Policlinico

Address:
City: Bari
Zip: 70124
Country: Italy

Status: Withdrawn

Facility:
Name: Azienda Ospedaliero Universitaria Ospedali Riuniti_Foggia - Oncologia Medica e Terapia Biomolecolare Universitaria

Address:
City: Foggia
Zip: 71122
Country: Italy

Status: Not yet recruiting

Facility:
Name: Azienda Provinciale Per I Servizi Sanitari_Ospedale Santa Chiara - UO Oncologia Medica

Address:
City: Trento
Zip: 38122
Country: Italy

Status: Not yet recruiting

Facility:
Name: A.O. di Perugia_Hospital Santa Maria della Misericordia - S.C. Radioterapia Oncologica

Address:
City: Perugia
Zip: 06129
Country: Italy

Status: Not yet recruiting

Facility:
Name: Istituto Oncologico Veneto_Castelfranco Veneto - UOC Urologia Oncologica

Address:
City: Castelfranco Veneto
Zip: 31033
Country: Italy

Status: Not yet recruiting

Facility:
Name: Azienda Ospedaliera Policlinico Universitario Tor Vergata - UOC Radioterapia

Address:
City: Roma
Zip: 00133
Country: Italy

Status: Not yet recruiting

Facility:
Name: IRCCS Ospedale Sacro Cuore Don Calabria

Address:
City: Verona
Zip: 37024
Country: Italy

Status: Withdrawn

Facility:
Name: A.O.U.I. Verona

Address:
City: Verona
Zip: 37134
Country: Italy

Status: Withdrawn

Facility:
Name: Cliniche Gavazzeni S.p.A - Dipartimento Area Chirurgia Unità Operativa di Urologia

Address:
City: Bergamo
Zip: 24125
Country: Italy

Status: Not yet recruiting

Facility:
Name: Hokkaido University Hospital

Address:
City: Sapporo
Zip: 060-8648
Country: Japan

Status: Recruiting

Facility:
Name: Kanazawa University Hospital

Address:
City: Kanazawa
Zip: 920-8641
Country: Japan

Status: Not yet recruiting

Facility:
Name: Yokohama City University Hospital

Address:
City: Yokohama
Zip: 236-0004
Country: Japan

Status: Recruiting

Facility:
Name: Osaka University Hospital

Address:
City: Suita
Zip: 565-0871
Country: Japan

Status: Recruiting

Facility:
Name: Institute of Science Tokyo Hospital

Address:
City: Bunkyo-ku
Zip: 113-8519
Country: Japan

Status: Recruiting

Facility:
Name: Kagoshima University Hospital

Address:
City: Kagoshima
Zip: 890-8520
Country: Japan

Status: Withdrawn

Facility:
Name: Kyoto University Hospital

Address:
City: Kyoto
Zip: 606-8507
Country: Japan

Status: Recruiting

Facility:
Name: Catharina Ziekenhuis

Address:
City: Eindhoven
Zip: 5623 EJ
Country: Netherlands

Status: Withdrawn

Facility:
Name: Albert Schweitzer Hospital | Internal Medicine - Oncology Department

Address:
City: Dordrecht
Zip: 3300 AK
Country: Netherlands

Status: Not yet recruiting

Facility:
Name: University Medical Center Groningen | Urology Department

Address:
City: Groningen
Zip: 9713 GZ
Country: Netherlands

Status: Not yet recruiting

Facility:
Name: Tergooi MC | Hilversum - Wetenschapsbureau

Address:
City: Hilversum
Zip: 1213 XZ
Country: Netherlands

Status: Not yet recruiting

Facility:
Name: St. Antonius Ziekenhuis | Utrecht - R&D Interne Geneeskunde

Address:
City: Nieuwegein
Zip: 3435 CM
Country: Netherlands

Status: Not yet recruiting

Facility:
Name: St. Franciscus Gasthuis

Address:
City: Rotterdam
Zip: 3045 PM
Country: Netherlands

Status: Not yet recruiting

Facility:
Name: HagaZiekenhuis van Den Haag

Address:
City: The Hague
Zip: 2545
Country: Netherlands

Status: Recruiting

Facility:
Name: Auckland City Hosptial

Address:
City: Auckland
Zip: 1023
Country: New Zealand

Status: Recruiting

Facility:
Name: Canterbury Urology Research Trust

Address:
City: Christchurch
Zip: 8013
Country: New Zealand

Status: Recruiting

Facility:
Name: Tauranga Urology Research Limited

Address:
City: Tauranga
Zip: 3112
Country: New Zealand

Status: Not yet recruiting

Facility:
Name: MidCentral District Health Board (MDHB) - Palmerston North Hospital (PNH)

Address:
City: TBC
Zip: 4414
Country: New Zealand

Status: Not yet recruiting

Facility:
Name: Centrum Onkologii im. Prof. Franciszka Lukaszczyka

Address:
City: Bydgoszcz
Zip: 85-796
Country: Poland

Status: Not yet recruiting

Facility:
Name: Swietokrzyskie Centrum Onkologii

Address:
City: Kielce
Zip: 25-734
Country: Poland

Status: Not yet recruiting

Facility:
Name: Centrum Medyczne iMed24

Address:
City: Krakow
Zip: 31-864
Country: Poland

Status: Not yet recruiting

Facility:
Name: Medrise Sp. z o.o. Centrum Badan Klinicznych

Address:
City: Lublin
Zip: 20-582
Country: Poland

Status: Not yet recruiting

Facility:
Name: Szpital Grochowski im. dr.med. Rafala Masztaka

Address:
City: Warszawa
Zip: 04-073
Country: Poland

Status: Not yet recruiting

Facility:
Name: EMC Instytut Medyczny SA

Address:
City: Wroclaw
Zip: 54-144
Country: Poland

Status: Recruiting

Facility:
Name: Instituto Portugues de Oncologia de Lisboa | Unidade de Investigacao Clinica - Departamento de Urologia

Address:
City: Lisbon
Zip: 1099-023
Country: Portugal

Status: Not yet recruiting

Facility:
Name: Centro Clinico Academico Braga | Braga, Portugal

Address:
City: Braga
Zip: 4710-243
Country: Portugal

Status: Withdrawn

Facility:
Name: Centro Hospitalar e Universitario de Coimbra EPE (CHUC)

Address:
City: Coimbra
Zip: 3004-561
Country: Portugal

Status: Not yet recruiting

Facility:
Name: Companhia Uniao Fabril | Hospital CUF Tejo - Academic Center - Research Center

Address:
City: Lisboa
Zip: 1350-352
Country: Portugal

Status: Not yet recruiting

Facility:
Name: Fundacao Champalimaud | Centro Clinico Champalimaud - Unidade Investigacao Clinica

Address:
City: Lisboa
Zip: 1400-038
Country: Portugal

Status: Withdrawn

Facility:
Name: Luz Saude | Hospital da Luz Lisboa - Centro de Investigacao Clinica

Address:
City: Lisboa
Zip: 1500-650
Country: Portugal

Status: Not yet recruiting

Facility:
Name: Hospital Santa Maria | Centro de Investigacao Clinica

Address:
City: Lisboa
Zip: 1649-035
Country: Portugal

Status: Not yet recruiting

Facility:
Name: Centro Hospitalar Universitario do Porto

Address:
City: Porto
Zip: 4099-001
Country: Portugal

Status: Withdrawn

Facility:
Name: Hospital Clínico Universitario de Santiago de Compostela

Address:
City: Santiago de Compostela
Zip: 15706
Country: Spain

Status: Recruiting

Facility:
Name: Hospital Universitario "Marqués de Valdecilla"

Address:
City: Santander
Zip: 39008
Country: Spain

Status: Not yet recruiting

Facility:
Name: Hospital Universitario Virgen de la Victoria | Cardiology Department

Address:
City: Malaga
Zip: 29010
Country: Spain

Status: Recruiting

Facility:
Name: Hospital del Mar

Address:
City: Barcelona
Zip: 08003
Country: Spain

Status: Recruiting

Facility:
Name: Ciutat Sanitaria i Universitaria de la Vall d'Hebron

Address:
City: Barcelona
Zip: 08035
Country: Spain

Status: Recruiting

Facility:
Name: Hospital Fundació Puigvert

Address:
City: Barcelona
Zip: 8025
Country: Spain

Status: Not yet recruiting

Facility:
Name: Hospital Clínic i Provincial de Barcelona

Address:
City: Barcelona
Zip: 8036
Country: Spain

Status: Recruiting

Facility:
Name: Hospital Universitario Puerta del Mar

Address:
City: Cadiz
Zip: 11009
Country: Spain

Status: Not yet recruiting

Facility:
Name: MD Anderson International Espanya, S.A.

Address:
City: Madrid
Zip: 28033
Country: Spain

Status: Not yet recruiting

Facility:
Name: Hospital Universitario Ramon y Cajal

Address:
City: Madrid
Zip: 28034
Country: Spain

Status: Recruiting

Facility:
Name: Centro Integral Oncológico Clara Campal

Address:
City: Madrid
Zip: 28050
Country: Spain

Status: Not yet recruiting

Facility:
Name: H. General Uiversitario Morales Meseguer - Department of Urology

Address:
City: Murcia
Zip: 30008
Country: Spain

Status: Not yet recruiting

Facility:
Name: Virgen del Rocio University Hospital - Oncology Department

Address:
City: Sevilla
Zip: 41013
Country: Spain

Status: Recruiting

Facility:
Name: Hospital Universitari i Politècnic La Fe

Address:
City: Valencia
Zip: 46009
Country: Spain

Status: Recruiting

Facility:
Name: Instituto Valenciano de Oncología

Address:
City: Valencia
Zip: 46009
Country: Spain

Status: Recruiting

Facility:
Name: Goteborgs Universitet

Address:
City: Gothenburg
Zip: 413 45
Country: Sweden

Status: Not yet recruiting

Facility:
Name: Skane University Hospital - Department of Urology

Address:
City: Malmo
Zip: 20502
Country: Sweden

Status: Recruiting

Facility:
Name: Uppsala University Hospital, Urology Department

Address:
City: Uppsala
Zip: SE-751
Country: Sweden

Status: Withdrawn

Facility:
Name: Tungs' Taichung MetroHarbor Hospital

Address:
City: Taichung
Zip: 435403
Country: Taiwan

Status: Not yet recruiting

Facility:
Name: National Taiwan University Hospital

Address:
City: Taipei
Zip: 100
Country: Taiwan

Status: Not yet recruiting

Facility:
Name: Koo Foundation Sun Yet-Sen Cancer Centre

Address:
City: Taipei
Zip: TBC
Country: Taiwan

Status: Recruiting

Facility:
Name: Chang Gung Memorial Hospital at Linkou

Address:
City: Taoyuan
Zip: 33305
Country: Taiwan

Status: Not yet recruiting

Facility:
Name: Bedford Hospital - Bedfordshire Hospitals NHS Foundation Tru

Address:
City: Bedford
Zip: MK42 9DJ
Country: United Kingdom

Status: Withdrawn

Facility:
Name: East and North Hertfordshire NHS Trust - Mount Vernon Hospital - Mount Vernon Cancer Centre (MVCC)

Address:
City: Northwood
Zip: HA6 2RN
Country: United Kingdom

Status: Recruiting

Facility:
Name: Royal Surrey County Hospital

Address:
City: Guildford
Zip: GU2 7XX
Country: United Kingdom

Status: Recruiting

Facility:
Name: Royal Marsden Hospital (London)

Address:
City: London
Zip: SW3 6JJ
Country: United Kingdom

Status: Not yet recruiting

Facility:
Name: University College London Hospitals NHS Foundation Trust

Address:
City: London
Zip: W1T 7HA
Country: United Kingdom

Status: Recruiting

Facility:
Name: Charing Cross Hospital

Address:
City: London
Zip: W6 8RF
Country: United Kingdom

Status: Recruiting

Start date: April 3, 2023

Completion date: February 28, 2029

Lead sponsor:
Agency: Bayer
Agency class: Industry

Source: Bayer

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05794906
http://clinicaltrials.bayer.com/