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Trial Title:
A Multicenter Prospective Cohort Study Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction Failure
NCT ID:
NCT05875649
Condition:
AML
Conditions: Official terms:
Leukemia
Leukemia, Myeloid
Leukemia, Myeloid, Acute
Conditions: Keywords:
CLAG
acute myeloid leukemia
First-induction failure
Study type:
Observational [Patient Registry]
Overall status:
Not yet recruiting
Study design:
Time perspective:
Prospective
Intervention:
Intervention type:
Combination Product
Intervention name:
CLAG
Description:
Acute myeloid leukemia patients are re-induced by CLAG Regimen after first-induction
failure
Arm group label:
Group
Summary:
Most of patients with acute myeloid leukemia achieved complete remission (CR) after
primary induction chemotherapy, there were 20-30% patients without CR after
first-induction. It was uncertain how to treat these patients. It was investigated in our
study that these patients were re-induced with CLAG Regimen. The CR ratio, overall
survival (OS) and relapsed-free survival (RFS) was statistically analysed in these
patients.
Criteria for eligibility:
Study pop:
Acute myeloid leukemia patients don't achieve CR after first-induction chemotherapy.
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Acute myeloid leukemia patients with first-induction failure
Exclusion Criteria:
- Acute myeloid leukemia patients with serious infection and organ dysfunction.
Gender:
All
Minimum age:
14 Years
Maximum age:
65 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Nanfang Hospital of Southern Medical University
Address:
City:
Guanzhou
Zip:
510515
Country:
China
Facility:
Name:
Nanfang Hospital of Southern Medical University
Address:
City:
Guanzhou
Zip:
510515
Country:
China
Contact:
Last name:
Xuejie Jiang, doctor
Phone:
+8618688869522
Email:
jxj3331233@163.com
Start date:
July 2, 2023
Completion date:
December 20, 2027
Lead sponsor:
Agency:
Nanfang Hospital, Southern Medical University
Agency class:
Other
Source:
Nanfang Hospital, Southern Medical University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05875649
