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Trial Title: Deep Learning Signature for Predicting Aggressive Histological Pattern in Resected Non-small Cell Lung Cancer

NCT ID: NCT05925738

Condition: Non-small Cell Lung Cancer
Spread Through Air Space
Visceral Pleural Invasion
Lymphovascular Invasion

Conditions: Official terms:
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung

Study type: Observational

Overall status: Recruiting

Study design:

Time perspective: Prospective

Intervention:

Intervention type: Diagnostic Test
Intervention name: PET/CT-based Deep Learning Signature
Description: Deep Learning Signature Based on PET-CT for Predicting the Aggressive Histological Pattern in Resected Non-small Cell Lung Cancer

Summary: The purpose of this study is to evaluate the performance of a PET/ CT-based deep learning signature for predicting aggressive histological pattern in resected non-small cell lung cancer based on a multicenter prospective cohort.

Criteria for eligibility:

Study pop:
Resected Stage I-III Non-small Cell Lung Cancer

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: (1) Participants scheduled for surgery for radiological finding of pulmonary lesions from the preoperative thin-section CT scans; (2) Pathological confirmation of primary NSCLC; (3) Age ranging from 20-75 years; (4) Obtained written informed consent. Exclusion Criteria: (1) Multiple lung lesions; (2) Poor quality of PET-CT images; (3) Participants with incomplete clinical information; (4) Participants who have received neoadjuvant therapy.

Gender: All

Minimum age: 20 Years

Maximum age: 75 Years

Healthy volunteers: Accepts Healthy Volunteers

Locations:

Facility:
Name: Affiliated Hospital of Zunyi Medical University

Address:
City: Zunyi
Country: China

Status: Recruiting

Contact:
Last name: Yongxiang Song, Dr

Phone: 15505177258
Email: zhong961008@163.com

Facility:
Name: The First Affiliated Hospital of Nanchang University

Address:
City: Nanchang
Country: China

Status: Recruiting

Contact:
Last name: Bentong Yu, Dr

Phone: 021-65115006
Email: 1151697503@qq.com

Facility:
Name: Ningbo HwaMei Hospital

Address:
City: Ningbo
Country: China

Status: Recruiting

Contact:
Last name: Minglei Yang, Dr

Phone: 021-65115006
Email: almondjj@163.com

Start date: May 1, 2023

Completion date: October 31, 2023

Lead sponsor:
Agency: Shanghai Pulmonary Hospital, Shanghai, China
Agency class: Other

Collaborator:
Agency: Ningbo No.2 Hospital
Agency class: Other

Collaborator:
Agency: Zunyi Medical College
Agency class: Other

Collaborator:
Agency: The First Affiliated Hospital of Nanchang University
Agency class: Other

Source: Shanghai Pulmonary Hospital, Shanghai, China

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT05925738

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