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Trial Title:
Effect of Stellate Ganglion Block on New Atrial Fibrillation After Coronary Artery Bypass Grafting
NCT ID:
NCT05932485
Condition:
Stellate Ganglion Block
Conditions: Official terms:
Ganglion Cysts
Synovial Cyst
Atrial Fibrillation
Study type:
Interventional
Study phase:
N/A
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Prevention
Masking:
Triple (Participant, Investigator, Outcomes Assessor)
Intervention:
Intervention type:
Procedure
Intervention name:
Stellate nerve block
Description:
Before the operation, the left stellate ganglion block was performed, and 0.375%
ropivacaine 5ml was injected into the stellate ganglion.
Arm group label:
Left stellate ganglion block
Summary:
Post-operative new-onset atrial fibrillation (POAF) is one of the most common arrhythmias
in adults after direct intracardiac surgery with extracorporeal circulation. The
incidence of POAF in coronary artery bypass grafting (CABG) is approximately 30%. POAF
can lead to an increased risk of complications such as stroke, heart failure, and acute
kidney injury, which not only prolongs the patient's hospital stay, but also increases
hospital costs and mortality. operation, extracorporeal circulation, and the patient's
underlying conditions (such as age, gender, hypertension, and diabetes), which cause
sympathetic activation, inflammatory response, and myocardial ischemia in the organism.
The stellate ganglion block (SGB) regulates the sympathetic tone of the innervated nerves
and thus the autonomic function of the body. SGB can effectively regulate the
sympathetic-parasympathetic imbalance. Also, SGB may exert some anti-inflammatory
effects. In this study, ultrasound-guided SGB was used in CABG patients to investigate
its effect on the occurrence of POAF.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Patients undergoing first-time and elective coronary artery bypass grafting;
- ASA grade II-IV；
- The preoperative ECG showed sinus heart rate.
Exclusion Criteria:
- The patient refused to participate in this study;
- Surgical procedures include any other type of heart surgery in addition to CABG；
- Allergic to known general anesthesia drugs;
- Patients with a history of neck surgery or abnormal neck anatomy;
- Patients with contraindications to SGB.
Gender:
All
Minimum age:
18 Years
Maximum age:
80 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
the Affiliated Hospital of Yangzhou University, Yangzhou University
Address:
City:
Yangzhou
Country:
China
Status:
Recruiting
Contact:
Last name:
Zhuan Zhang, professor
Phone:
+8615062791355
Phone ext:
+8615062791355
Email:
zhangzhuancg@163.com
Start date:
June 1, 2023
Completion date:
June 1, 2024
Lead sponsor:
Agency:
Yangzhou University
Agency class:
Other
Source:
Yangzhou University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05932485
