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Trial Title:
Establishment of a Tissue Registry for Hepatocellular Carcinoma Specimens
NCT ID:
NCT05935189
Condition:
Hepatocellular Carcinoma
Conditions: Official terms:
Carcinoma
Carcinoma, Hepatocellular
Study type:
Observational [Patient Registry]
Overall status:
Recruiting
Study design:
Time perspective:
Prospective
Summary:
The goal of the study is to establish a cancer registry to facilitate research and assist
in the identification of additional risk factors for hepatocellular carcinoma. The main
objectives are:
1. provide a mechanism to store the information about subjects with hepatocellular
carcinoma
2. use of tissue samples for translational/further research purposes
Detailed description:
The Establishment of a Tissue Registry for Hepatocellular Carcinoma biopsy specimens for
genetic and histologic research (TIR-HCC) is a project aimed at addressing the high
incidence rates of primary liver cancer in Armenia. This initiative seeks to establish a
cancer registry to support research efforts and identify additional risk factors
associated with hepatocellular carcinoma (HCC).
The study will involve patients of Armenian descent who exhibit clinical, biochemical,
and imaging evidence of hepatocellular carcinoma. Data collection will include tissue and
blood samples, which will undergo histologic and genetic analyses. Additionally, relevant
clinical history, laboratory results, imaging findings, and gut microbiota profiles will
be collected.
To ensure a comprehensive dataset, samples will be collected from eight institutions in
Armenia. The project aims to accumulate data from a total of 500 patients, providing a
substantial pool for research and analysis.
By establishing the TIR-HCC registry, researchers hope to contribute to the understanding
of hepatocellular carcinoma and potentially identify new risk factors associated with the
disease. The collected data will aid in advancing knowledge of HCC and guide future
strategies for prevention, early detection, and treatment.
Criteria for eligibility:
Study pop:
The study population is composed of individuals from Armenian descent who have a
biopsy-confirmed diagnosis of hepatocellular carcinoma.
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Patients with biopsy-confirmed diagnosis of HCC
- Armenian descent
- Having given their signed Informed consent
Exclusion Criteria:
- Failure to obtain informed consent
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Nikomed Medical Center
Address:
City:
Yerevan
Country:
Armenia
Status:
Recruiting
Contact:
Last name:
Hasmik Ghazinian, MD
Phone:
91423802
Phone ext:
+374
Email:
ghazinian@gmail.com
Start date:
July 1, 2023
Completion date:
July 1, 2028
Lead sponsor:
Agency:
Nikomed Medical Center
Agency class:
Other
Source:
Nikomed Medical Center
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05935189
https://pubmed.ncbi.nlm.nih.gov/33538338/
