Trial Title:
A Registry for People With T-cell Lymphoma
NCT ID:
NCT05978141
Condition:
T-cell Lymphoma
NK-Cell Lymphoma
T-cell Prolymphocytic Leukemia
T-cell Large Granular Lymphocytic Leukemia
Chronic Lymphoproliferative Disorder of NK Cells
Aggressive NK-cell Leukemia
Systemic Epstein-Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood (Disorder)
Systemic Epstein Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood
Chronic Active EBV Infection of T-and NK-Cell Type, Systemic Form
Hydroa Vacciniforme-Like Lymphoproliferative Disorder
Adult T-cell Leukemia/Lymphoma
Extranodal NK/T-cell Lymphoma, Nasal Type
Enteropathy-associated T-cell Lymphoma
Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma
Intestinal T-Cell Lymphoma, Not Otherwise Specified
Indolent T-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract
Hepatosplenic T-cell Lymphoma
Subcutaneous Panniculitis-Like T-Cell Lymphoma
Mycosis Fungoides
Sezary Syndrome
Primary Cutaneous Anaplastic Large Cell Lymphoma
Primary Cutaneous T-cell Lymphoma
Primary Cutaneous CD8-Positive Aggressive Epidermotropic T-Cell Lymphoma
Primary Cutaneous Acral CD8-Positive T-Cell Lymphoma
Peripheral T-Cell Lymphoma, Not Otherwise Specified
Angioimmunoblastic T-cell Lymphoma
Follicular T-Cell Lymphoma
Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
Anaplastic Large Cell Lymphoma, ALK-Positive
Anaplastic Large Cell Lymphoma, ALK-negative
Breast Implant-Associated Anaplastic Large Cell Lymphoma
Conditions: Official terms:
Mycoses
Epstein-Barr Virus Infections
Lymphoma
Leukemia
Lymphoma, Non-Hodgkin
Lymphoma, T-Cell
Lymphoma, T-Cell, Peripheral
Mycosis Fungoides
Sezary Syndrome
Leukemia, T-Cell
Leukemia-Lymphoma, Adult T-Cell
Lymphoma, Large-Cell, Anaplastic
Lymphoma, T-Cell, Cutaneous
Lymphoma, Extranodal NK-T-Cell
Leukemia, Prolymphocytic
Leukemia, Large Granular Lymphocytic
Leukemia, Prolymphocytic, T-Cell
Enteropathy-Associated T-Cell Lymphoma
Lymphoma, Primary Cutaneous Anaplastic Large Cell
Lymphoproliferative Disorders
Immunoblastic Lymphadenopathy
Panniculitis
Hydroa Vacciniforme
Aggression
Conditions: Keywords:
23-190
T-cell lymphoma
Memorial Sloan Kettering Cancer Center
T-cell Lymphoma Master Repository
TCLMR
Study type:
Observational [Patient Registry]
Overall status:
Recruiting
Study design:
Time perspective:
Prospective
Intervention:
Intervention type:
Other
Intervention name:
Optional Blood Sample and Nail Sample
Description:
Participants may provide optional research blood and nail samples for biobanking and
future use
Arm group label:
Participants with T-Cell Lymphoma
Summary:
The purpose of this registry study is to create a database-a collection of
information-for better understanding T-cell lymphoma. Researchers will use the
information from this database to learn more about how to improve outcomes for people
with T-cell lymphoma.
Criteria for eligibility:
Study pop:
Participants at Memorial Sloan Kettering Cancer Center (MSKCC) will be recruited through
the Lymphoma service in the Department of Medicine and the Department of Pediatrics.
Participants will be recruited at the participating centers.
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Written informed consent
- Adequate fresh or archival tumor biopsy or intent to obtain fresh tumor biopsy.
- Pathologically-confirmed mature T- or natural killer (NK)-cell lymphoma meeting one
of the following diagnostic criterion (based on WHO classification and NCCN
guidelines):
- T-cell prolymphocytic leukemia
- T-cell large granular lymphocytic leukemia
- Chronic lymphoproliferative disorder of NK cells
- Aggressive NK-cell leukemia
- Systemic Epstein-Barr virus (EBV)-positive T-cell lymphoma of childhood
- Chronic active EBV infection of T- and NK-cell type, systemic form
- Hydroa vacciniforme-like lymphoproliferative disorder
- Adult T-cell leukemia/lymphoma
- Extranodal NK/T-cell lymphoma, nasal type
- Enteropathy-associated T-cell lymphoma
- Monomorphic epitheliotropic intestinal T-cell lymphoma
- Intestinal T-cell lymphoma, not otherwise specified (NOS)
- Indolent T-cell lymphoproliferative disorder of the gastrointestinal tract
- Hepatosplenic T-cell lymphoma
- Subcutaneous panniculitis-like T-cell lymphoma
- Mycosis fungoides (limited to those with ≥ stage IB disease and those receiving
active therapy)
- Sézary syndrome
- Primary cutaneous anaplastic large cell lymphoma (receiving systemic therapy)
- Primary cutaneous Gamma-Delta T-cell lymphoma
- Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma
- Primary cutaneous acral CD8+ T-cell lymphoma (receiving systemic therapy)
- Peripheral T-cell lymphoma, not otherwise specified
- Angioimmunoblastic T-cell lymphoma
- Follicular T-cell lymphoma
- Nodal peripheral T-cell lymphoma with TFH phenotype
- Anaplastic large cell lymphoma, ALK-positive
- Anaplastic large cell lymphoma, ALK-negative
- Breast-implant associated anaplastic large cell lymphoma.
- NOTE: Patients with diagnoses of mycosis fungoides, primary cutaneous anaplastic
large cell lymphoma, and/or primary cutaneous acral CD8+ T-cell lymphoma must be
receiving systemic therapy.
Exclusion Criteria:
- Patients with of mycosis fungoides, primary cutaneous anaplastic large cell
lymphoma, and/or primary cutaneous acral CD8+ T-cell lymphoma not receiving systemic
therapy.
- Inability to collect prospective data, measure response, or perform adequate
follow-up assessments in the clinical judgment of the treating physician. NOTE:
Repository participation does not exclude participation in clinical trials, nor does
existing clinical trial participation exclude enrollment in the study herein
outlined.
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
City of Hope Cancer Center (Data collection only)
Address:
City:
Duarte
Zip:
91010
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Jasmine Zain, MD
Phone:
626-359-8111
Facility:
Name:
UNIVERSITY OF CALIFORNIA SAN DIEGO (Data collection only)
Address:
City:
San Diego
Zip:
92103
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Aaron Goodman, MD
Phone:
858-822-6100
Facility:
Name:
University of California San Francisco (Data collection only)
Address:
City:
San Francisco
Zip:
94143
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Weiyun Ai, MD
Phone:
415-353-2421
Facility:
Name:
Stanford University Medical Center (Data collection only)
Address:
City:
Stanford
Zip:
94305-5408
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Michael Khodadoust, MD
Phone:
650-725-5071
Facility:
Name:
University of Colorado (Data Collection Only)
Address:
City:
Aurora
Zip:
80045
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Bradley Haverkos, MD
Phone:
212-639-3983
Facility:
Name:
Yale University (Data Collection Only)
Address:
City:
New Haven
Zip:
06511
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Francine Foss, MD
Phone:
203-200-4363
Facility:
Name:
University of Miami (Data Collection Only)
Address:
City:
Miami
Zip:
33136
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Jonathan Schatz, MD
Phone:
305-243-5302
Facility:
Name:
Moffitt Cancer Center (Data Collection Only)
Address:
City:
Tampa
Zip:
33612
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Lubomir Sokol, MD, PhD
Phone:
888-663-3488
Facility:
Name:
Emory University (Data Collection Only)
Address:
City:
Atlanta
Zip:
30322
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Pamela Allen, MD, MSc
Phone:
404-778-0519
Facility:
Name:
Northwestern Medicine (Data Collection)
Address:
City:
Chicago
Zip:
60611
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Jaehyuk Choi, MD, PhD
Phone:
312-695-8106
Facility:
Name:
Massachusetts General Hospital (Data Collection Only)
Address:
City:
Boston
Zip:
02114
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Salvia Jain, MD
Phone:
857-392-4495
Facility:
Name:
Dana Farber Cancer Institute (Data Collection Only)
Address:
City:
Boston
Zip:
02115
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Eric D Jacobsen, MD
Phone:
877-442-3324
Facility:
Name:
Mayo Clinic (Data Collection Only)
Address:
City:
Rochester
Zip:
55905
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Nora Bennani, MD
Phone:
507-284-2511
Facility:
Name:
Washington University (Data Collection Only)
Address:
City:
Saint Louis
Zip:
63110
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Neha Mehta-Shah, MD, MSCI
Phone:
314-747-1171
Facility:
Name:
University of Nebraska (Data collection only)
Address:
City:
Omaha
Zip:
68198-7680
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Matthew Lunning, DO, FACP
Phone:
402-559-4000
Facility:
Name:
Memorial Sloan Kettering at Basking Ridge (All protocol activities)
Address:
City:
Basking Ridge
Zip:
07920
Country:
United States
Status:
Recruiting
Contact:
Last name:
Steven Horwitz, MD
Phone:
646-608-2680
Facility:
Name:
Memorial Sloan Kettering Monmouth (All protocol activities)
Address:
City:
Middletown
Zip:
07748
Country:
United States
Status:
Recruiting
Contact:
Last name:
Steven Horwitz, MD
Phone:
646-608-2680
Facility:
Name:
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (All protocol activities)
Address:
City:
Commack
Zip:
11725
Country:
United States
Status:
Recruiting
Contact:
Last name:
Steven Horwitz, MD
Phone:
646-608-2680
Facility:
Name:
Memorial Sloan Kettering Westchester (All protocol activities)
Address:
City:
Harrison
Zip:
10604
Country:
United States
Status:
Recruiting
Contact:
Last name:
Steven Horwitz, MD
Phone:
646-608-2680
Facility:
Name:
Weill Cornell Medical Center (Data Collection Only)
Address:
City:
New York
Zip:
10021
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Jia Ruan, MD, PhD
Phone:
646-962-2064
Facility:
Name:
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
Address:
City:
New York
Zip:
10065
Country:
United States
Status:
Recruiting
Contact:
Last name:
Steven Horwitz, MD
Phone:
646-608-2680
Facility:
Name:
Memorial Sloan Kettering Nassau (All protocol activities)
Address:
City:
Uniondale
Zip:
11553
Country:
United States
Status:
Recruiting
Contact:
Last name:
Steven Horwitz, MD
Phone:
646-608-2680
Facility:
Name:
Ohio State University (Data Collection Only)
Address:
City:
Columbus
Zip:
43210
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
John Reneau, MD, PhD
Phone:
614-293-8000
Facility:
Name:
University of Pennsylvania (Data Collection Only)
Address:
City:
Philadelphia
Zip:
19104
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Stefan Barta, MD, MS, MRCPCUK
Phone:
(215) 316-5151
Facility:
Name:
Thomas Jefferson University Hospital (Data collection only)
Address:
City:
Philadelphia
Zip:
19107
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Pierluigi Porcu, MD
Phone:
215-955-8874
Facility:
Name:
MD Anderson Cancer Center (Data Collection Only)
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Swami Iyer, MD
Phone:
713-352-2952
Start date:
July 27, 2023
Completion date:
July 27, 2030
Lead sponsor:
Agency:
Memorial Sloan Kettering Cancer Center
Agency class:
Other
Source:
Memorial Sloan Kettering Cancer Center
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05978141
http://www.mskcc.org
