Trial Title:
IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma
NCT ID:
NCT05987332
Condition:
Metastatic Uveal Melanoma
Conditions: Official terms:
Melanoma
Uveal Neoplasms
Pembrolizumab
Nivolumab
Ipilimumab
Dacarbazine
Crizotinib
Conditions: Keywords:
IDE196
Darovasertib
Protein Kinase C
Metastatic Uveal Melanoma
Melanoma
Ocular Oncology
Ophthalmology
Crizotinib
Ocular melanoma
Study type:
Interventional
Study phase:
Phase 2/Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Sequential Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
IDE196
Description:
Dosed orally, twice daily
Arm group label:
Phase 2a Dose Optimization of IDE196 + crizotinib
Arm group label:
Phase 2b / 3 Chosen Combination dose of IDE196 + crizotinib
Other name:
Darovasertib
Intervention type:
Drug
Intervention name:
Crizotinib
Description:
Dosed orally, twice daily
Arm group label:
Phase 2a Dose Optimization of IDE196 + crizotinib
Arm group label:
Phase 2b / 3 Chosen Combination dose of IDE196 + crizotinib
Other name:
XALKORI
Intervention type:
Drug
Intervention name:
Pembrolizumab
Description:
IV administration every 3 weeks
Arm group label:
Phase 2a / 2b / 3 Comparator Arm
Other name:
Keytruda
Intervention type:
Drug
Intervention name:
Ipilimumab
Description:
IV administration every 3 weeks for 4 Cycles
Arm group label:
Phase 2a / 2b / 3 Comparator Arm
Other name:
Yervoy
Intervention type:
Drug
Intervention name:
Nivolumab
Description:
IV administration every 3 Weeks for 4 Cycles, thereafter every 4 Weeks maintenance
Arm group label:
Phase 2a / 2b / 3 Comparator Arm
Other name:
Opdivo
Intervention type:
Drug
Intervention name:
Dacarbazine
Description:
IV administration every 3 Weeks
Arm group label:
Phase 2a / 2b / 3 Comparator Arm
Other name:
DTIC-Dome
Summary:
This is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen
(HLA)-A*02:01 negative participants with metastatic uveal melanoma (MUM) who will be
randomized to receive either IDE196 + crizotinib or investigator's choice of treatment
(pembrolizumab, ipilimumab + nivolumab, or dacarbazine).
Detailed description:
This study is designed as a multi-stage Phase 2 study within a Phase 3 study to evaluate
the safety, tolerability, pharmacokinetics, dose-exposure relationship, and anti-tumor
activity of IDE196 in combination with crizotinib compared to the comparator arm of
investigator's choice of treatment (pembrolizumab, ipilimumab + nivolumab, or
dacarbazine).
The Phase 2a dose optimization stage will evaluate two doses of IDE196 in combination
with crizotinib compared to the comparator arm. Participants will be randomized to the
three treatment arms. At the point of optimal IDE196 + crizotinib dose selection, the
other dose arm will be dropped with discontinuation of enrollment to that arm.
Participants receiving the IDE196 dose (in combination with crizotinib) that is not
selected, will be offered the choice to remain on the same dose or change to the chosen
optimal dose.
The optimal dose will be chosen to complete the Phase 2b portion. The Phase 2b part of
the study will continue to enroll the chosen combination dose of IDE196 + crizotinib
compared with the comparator arm. Participants will be randomized to the two treatment
arms.
The Phase 3 part of the study will continue to enroll the chosen combination dose of
IDE196 + crizotinib compared with the comparator arm. Participants will be randomized to
the two treatment arms.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Histological or cytological confirmed Metastatic Uveal Melanoma
- HLA-A*02:01 negative
- No prior systemic therapy in the metastatic or advanced setting or regional or
liver-directed therapy. Ablations or surgical resection of oligometastatic disease,
and neoadjuvant or adjuvant therapy is allowed
- Measurable disease per RECIST 1.1
- Able to be safely administered and absorb study therapy
- ECOG performance status 0 or 1
- Life expectancy of ≥3 months
- Adequate organ function
Exclusion Criteria:
- Previous treatment with a PKC inhibitor (including prior treatment with IDE196), an
inhibitor directly targeting MET, or an inhibitor directly targeting GNAQ/11
- Concurrent malignant disease
- AEs from prior anti-cancer therapy that have not resolved to Grade ≤1
- Symptomatic or untreated central nervous system (CNS) metastases, or CNS metastases
that require corticosteroids
- High risk of syncope
- Known AIDS related illness or active Hep B/C
- Active adrenal insufficiency, active colitis, or active inflammatory bowel disease
- History of interstitial lung disease, active pneumonitis, or history of pneumonitis
- Active infection requiring systemic antibiotic therapy
- Use of hematopoietic colony-stimulating factors (CSF) prior to start of study drug
- Females who are pregnant or breastfeeding
- History of severe hypersensitivity reactions (eg, anaphylaxis) to other biologic
drugs or monoclonal antibodies
- Contraindication for treatment with investigator's choice therapies as per
applicable labelling
- History of stroke within the last 6 months of the first dose of study drug
- Has any other condition that may increase the risk associated with study
participation or may interfere with the interpretation of study results and, in the
opinion of the investigator, would make the participant inappropriate for entry into
the study, including institutionalization on the basis of an official or court order
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Honor Health
Address:
City:
Scottsdale
Zip:
85258
Country:
United States
Status:
Recruiting
Contact:
Last name:
Oncology Clinical Trials Nurse Navigator
Phone:
480-323-1791
Email:
clinicaltrials@honorhealth.com
Contact backup:
Phone:
833-354-6667
Facility:
Name:
Moores Cancer Center
Address:
City:
La Jolla
Zip:
92093
Country:
United States
Status:
Recruiting
Contact:
Last name:
Katie O'Neil, BA
Phone:
858-822-5354
Email:
croneil@health.ucsd.edu
Contact backup:
Last name:
Jazelle Molina
Phone:
858-822-5354
Email:
jgmolina@health.ucsd.edu
Facility:
Name:
UCLA Medical Center
Address:
City:
Los Angeles
Zip:
90024
Country:
United States
Status:
Recruiting
Contact:
Last name:
Adyel Annelus
Phone:
310-794-4955
Email:
aannelus@mednet.ucla.edu
Contact backup:
Last name:
Elizabeth Seja
Phone:
310-794-6892
Email:
eseja@mednet.ucla.edu
Facility:
Name:
The Angeles Clinic and Research Institute
Address:
City:
Los Angeles
Zip:
90025
Country:
United States
Status:
Recruiting
Contact:
Last name:
Saba Mukarram
Phone:
310-231-2181
Email:
smukarram@theangelesclinic.org
Facility:
Name:
California Pacific Medical Center (CPMC)
Address:
City:
San Francisco
Zip:
94115
Country:
United States
Status:
Recruiting
Contact:
Last name:
Denise Fortun
Phone:
415-600-1775
Email:
denise.fortun@sutterhealth.org
Contact backup:
Last name:
CPMC Clinical Research Group
Email:
clinicalresearch@sutterhealth.org
Facility:
Name:
University of California San Francisco
Address:
City:
San Francisco
Zip:
94143
Country:
United States
Status:
Recruiting
Contact:
Last name:
Sonia Contreras Martinez, BSN
Phone:
415-514-6427
Email:
sonia.contrerasmartinez@ucsf.edu
Facility:
Name:
University of Colorado Cancer Center
Address:
City:
Aurora
Zip:
80045
Country:
United States
Status:
Recruiting
Contact:
Last name:
Sarah Mayer, BA
Phone:
303-724-5056
Email:
sara.j.mayer@cuanschutz.edu
Contact backup:
Last name:
Victoria Mayer, VA
Phone:
303-724-9807
Email:
victoria.nuanes@cuanschutz.edu
Facility:
Name:
SCRI at HealthONE
Address:
City:
Denver
Zip:
80218
Country:
United States
Status:
Recruiting
Contact:
Last name:
SCRI Front Desk
Phone:
720-754-2610
Email:
cann.ddudenvergeneral@sarahcannon.com
Facility:
Name:
University of Miami Sylvester Comprehensive Cancer Center
Address:
City:
Miami
Zip:
33136
Country:
United States
Status:
Recruiting
Contact:
Email:
CRSCutaneous@miami.edu
Facility:
Name:
Moffitt Cancer Center
Address:
City:
Tampa
Zip:
33612
Country:
United States
Status:
Recruiting
Contact:
Last name:
Nikhil Khushalani, MD
Phone:
813-745-3437
Email:
Nikhil.khushalani@moffitt.org
Contact backup:
Last name:
Leticia Tetteh, BSN
Phone:
813-745-4617
Email:
Leticia.tetteh@moffitt.org
Facility:
Name:
Northside Hospital Atlanta
Address:
City:
Atlanta
Zip:
30342
Country:
United States
Status:
Recruiting
Contact:
Last name:
Central Research Department
Phone:
404-303-3355
Email:
clinicaltrials@northside.com
Facility:
Name:
University of Iowa
Address:
City:
Iowa City
Zip:
52242
Country:
United States
Status:
Recruiting
Contact:
Last name:
Asad Javed, MD
Phone:
319-467-5156
Email:
asad-javed@uiowa.edu
Facility:
Name:
Massachusetts General Hospital
Address:
City:
Boston
Zip:
02114
Country:
United States
Status:
Recruiting
Contact:
Last name:
Kamaneh Montazeri, MD
Phone:
617-724-4000
Email:
kmontazeri@mgh.harvard.edu
Contact backup:
Last name:
Ryan Sullivan, MD
Phone:
6177245197
Email:
rsullivan7@mgh.harvard.edu
Facility:
Name:
Dana Farber Cancer Institute
Address:
City:
Boston
Zip:
02215
Country:
United States
Status:
Recruiting
Contact:
Last name:
Rizwan Haq
Phone:
617-632-6168
Email:
rizwan_haq@dfci.harvard.edu
Contact backup:
Last name:
Linnea Drew
Phone:
617-632-6705
Email:
linneam_drew@dfci.harvard.edu
Facility:
Name:
The Cancer and Hematology Centers
Address:
City:
Grand Rapids
Zip:
49546
Country:
United States
Status:
Recruiting
Contact:
Last name:
The Cancer and Hematology Centers
Phone:
616-954-5550
Email:
ClinicalTrials@chcwm.com
Contact backup:
Last name:
Jessica Miller, RN
Phone:
616-954-5550
Phone ext:
1651
Email:
Jmiller@chcwm.com
Facility:
Name:
Minnesota Oncology Hematology, P.A.
Address:
City:
Burnsville
Zip:
55337
Country:
United States
Status:
Recruiting
Contact:
Last name:
Kayla McDonald
Email:
kayla.mcdonald1@usoncology.com
Facility:
Name:
Mayo Clinic
Address:
City:
Rochester
Zip:
55905
Country:
United States
Status:
Recruiting
Contact:
Last name:
Referral Office
Phone:
855-776-0015
Email:
mayocliniccancerstudies@mayo.edu
Facility:
Name:
Washington University School of Medicine
Address:
City:
Saint Louis
Zip:
63110
Country:
United States
Status:
Recruiting
Contact:
Last name:
Amer Alyasiry, MHS
Phone:
314-600-4605
Email:
aalyasiry@wustl.edu
Contact backup:
Last name:
Tyler Klein
Phone:
314-273-3072
Email:
kleint@wustl.edu
Facility:
Name:
Roswell Park Cancer Institute
Address:
City:
Buffalo
Zip:
14263
Country:
United States
Status:
Recruiting
Contact:
Last name:
Benjamin Switzer, DO
Phone:
716-845-7668
Email:
benjamin.switzer@rosewellpark.org
Contact backup:
Last name:
igor Puzanov, MD
Phone:
716-845-7505
Email:
igor.puzanov@roswellpark.org
Facility:
Name:
Northwell Health
Address:
City:
Manhasset
Zip:
11030
Country:
United States
Status:
Recruiting
Contact:
Last name:
Shaheer Khan, MD
Email:
skhan137@northwell.edu
Contact backup:
Last name:
Tracy Green, BS
Email:
tgreen22@northwell.edu
Facility:
Name:
Memorial Sloan Kettering Cancer Center
Address:
City:
New York
Zip:
10065
Country:
United States
Status:
Recruiting
Contact:
Last name:
Alexander Shoushtari, MD
Phone:
646-888-4161
Email:
shoushta@mskcc.org
Contact backup:
Last name:
James Smithy, MD
Phone:
929-623-0275
Email:
smithyj@mskcc.org
Facility:
Name:
Duke University Health System
Address:
City:
Durham
Zip:
27710
Country:
United States
Status:
Recruiting
Contact:
Last name:
Carol Ann Wiggs, BSN
Phone:
919-684-0281
Email:
carolann.wiggs@duke.edu
Contact backup:
Last name:
Emily Bolch
Phone:
919-668-6359
Email:
emily.bolch@duke.edu
Facility:
Name:
University of Cincinnati
Address:
City:
Cincinnati
Zip:
45267
Country:
United States
Status:
Recruiting
Contact:
Phone:
513-584-7698
Email:
cancer@uchealth.com
Facility:
Name:
The Cleveland Clinic Foundation
Address:
City:
Cleveland
Zip:
44195
Country:
United States
Status:
Recruiting
Contact:
Last name:
Lucy Kennedy, MD
Phone:
216-444-7923
Email:
KENNEDL5@ccf.org
Facility:
Name:
Thomas Jefferson University
Address:
City:
Philadelphia
Zip:
19107
Country:
United States
Status:
Recruiting
Contact:
Last name:
Marlana Orloff
Phone:
215-955-9980
Email:
Marlana.Orloff@Jefferson.edu
Contact backup:
Last name:
Kristie Hensel
Phone:
215-955-9980
Email:
Kristie.Hensel@Jefferson.edu
Facility:
Name:
University of Pittsburgh Medical Center
Address:
City:
Pittsburgh
Zip:
15232
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Amy Rose, RN,BSN
Phone:
412-647-8587
Email:
kennaj@upmc.edu
Contact backup:
Last name:
Jennifer Cleric, ND, RN
Phone:
412-864-7893
Email:
clericja@upmc.edu
Facility:
Name:
SCRI Oncology Partners
Address:
City:
Nashville
Zip:
37203
Country:
United States
Status:
Recruiting
Contact:
Last name:
SCRI Oncology Partners
Phone:
844-482-4812
Facility:
Name:
Texas Oncology- DFW
Address:
City:
Dallas
Zip:
75246
Country:
United States
Status:
Recruiting
Contact:
Last name:
Christine Terraciano
Phone:
214-370-1942
Email:
christine.terraciano@usoncology.com
Facility:
Name:
UT Southwestern Medical Center
Address:
City:
Dallas
Zip:
75390
Country:
United States
Status:
Recruiting
Contact:
Last name:
Sanjay Chandrasekaran, MD
Phone:
833-722-6237
Email:
sanjay.chandrasekaran@utsouthwestern.edu
Contact backup:
Last name:
Desiree Pierre, BS
Phone:
214-648-3111
Email:
desiree.pierre@utsouthwestern.edu
Facility:
Name:
Houston Methodist Cancer Center
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Contact:
Last name:
Anaum Maqsood
Phone:
713-441-9948
Email:
amaqsood@houstonmethodist.org
Facility:
Name:
MD Anderson Cancer Center
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Contact:
Last name:
Alexandra Ikeguchi
Email:
apikeguchi@mdanderson.org
Facility:
Name:
Westmead Hospital
Address:
City:
Sydney
Zip:
2145
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Matteo Carlino, MD
Phone:
+61 288 905 200
Email:
matteo.carlino@sydney.edu.au
Facility:
Name:
Princess Alexander Hospital
Address:
City:
Brisbane
Zip:
4102
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Janine Thomas
Phone:
+61(0)731767578
Email:
janine.thomas@health.qld.gov.au
Facility:
Name:
Peter MacCallum Cancer Centre
Address:
City:
Melbourne
Zip:
3000
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Damien Kee, MD
Email:
damien.kee@petermac.org
Facility:
Name:
Alfred Health
Address:
City:
Melbourne
Zip:
3168
Country:
Australia
Status:
Recruiting
Facility:
Name:
Sir Charles Gairdner Hospital
Address:
City:
Perth
Zip:
6009
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Joanne Tonkin
Phone:
0863833185
Email:
SCGH.MedOncCTM@health.wa.gov.au
Contact backup:
Last name:
Rose McDowell
Phone:
0863833190
Email:
Rose.McDowell@health.wa.gov.au
Facility:
Name:
Queen Elizabeth Hospital
Address:
City:
Adelaide
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Roberts-Thomson, MD
Facility:
Name:
Cliniques Universitaires Saint Luc
Address:
City:
Brussels
Zip:
1200
Country:
Belgium
Status:
Not yet recruiting
Contact:
Last name:
Jean Francois Baurain, MD
Email:
jean-francois.baurain@saintluc.uclouvain.be
Facility:
Name:
Cross Cancer Institute, University of Alberta
Address:
City:
Edmonton
Zip:
T6G 1Z2
Country:
Canada
Status:
Not yet recruiting
Contact:
Last name:
John Walker, MD,PhD,FRCPC
Phone:
780-577-8082
Email:
john.walker2@ahs.ca
Facility:
Name:
Princess Margaret Cancer Centre
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Melissa Dalva
Phone:
416-946-4501
Phone ext:
5485
Email:
Melissa.dalva@uhn.ca
Facility:
Name:
Centre Hospitalier de l'Universite de Montreal- CHUM
Address:
City:
Montréal
Zip:
H2X 0C1
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Rahima Jamal, MD
Phone:
514-890-8444
Email:
rahima.jamal.med@ssss.gouv.qc.ca
Contact backup:
Last name:
Chantal Gosselin
Phone:
514-890-8000
Phone ext:
24892
Email:
urcoh.eligibilite.chum@ssss.gouv.qc.ca
Facility:
Name:
The Leon Berard Center
Address:
City:
Lyon
Country:
France
Status:
Recruiting
Contact:
Last name:
Eve-Marie Neidhardt, MD
Email:
evemarie.neidhardt@lyon.unicancer.fr
Facility:
Name:
Institut Curie
Address:
City:
Paris
Zip:
75005
Country:
France
Status:
Recruiting
Contact:
Last name:
Sophie Piperno-Neumann, MD
Phone:
+33 0 1 44 32 40 68
Email:
sophie.piperno-neumann@curie.fr
Facility:
Name:
NCT Heidelberg
Address:
City:
Heidelberg
Zip:
69120
Country:
Germany
Status:
Not yet recruiting
Contact:
Last name:
Jessica Hassel, Prof. Dr. med
Email:
Studien-DermaOnko.NCT@med.uni-heidelberg.de
Facility:
Name:
Universitätsklinikum Essen (AöR)
Address:
City:
Essen
Zip:
45147
Country:
Germany
Status:
Not yet recruiting
Contact:
Last name:
Halime Kalkavan, Dr. med
Phone:
+49 201 72384150
Email:
halime.kalkavan@uk-essen.de
Facility:
Name:
Universitätsklinikum Köln
Address:
City:
Köln
Zip:
50937
Country:
Germany
Status:
Not yet recruiting
Contact:
Last name:
Nicole Kreuzberg, MD
Email:
halime.kalkavan@uk-essen.de
Facility:
Name:
Universitätsklinikum Carl Gustav Carus Dresden
Address:
City:
Dresden
Zip:
1307
Country:
Germany
Status:
Not yet recruiting
Contact:
Last name:
Friedegund Meier, Prof. Dr. med
Phone:
+49 (0) 351 458 19782
Email:
oncostudien.dermatologie@ukdd.de
Facility:
Name:
Charité - Universitätsmedizin Berlin
Address:
City:
Berlin
Zip:
12203
Country:
Germany
Status:
Not yet recruiting
Contact:
Last name:
Caroline Anna Peuker, MD
Phone:
+49 30 450 513470
Email:
caroline-anna.peuker@charite.de
Facility:
Name:
Hadassah Medical Center
Address:
City:
Jerusalem
Zip:
91120
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Jonathan Cohen, MD
Phone:
972 50 5172537
Email:
cohenjon@hadassah.org.il
Contact backup:
Last name:
Annaelle Dynovisz, SC
Phone:
972-58-4820222
Email:
annaelled@hadassah.org.il
Facility:
Name:
Sheba Medical Center
Address:
City:
Ramat-Gan
Zip:
52621
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Ronnie Shapira, MD
Phone:
972 3-5302243
Email:
ronnie.shapira@sheba.health.gov.il
Facility:
Name:
Fondazione IRCCS Istituto Nazionale dei Tumori
Address:
City:
Milano
Zip:
20133
Country:
Italy
Status:
Not yet recruiting
Contact:
Last name:
Lorenza DiGuardo, MD
Phone:
0039 02 23905000
Email:
Lorenza.DiGuardo@istitutotumori.mi.it
Facility:
Name:
Istituto Nazionale dei Tumori Fondazione Pascale
Address:
City:
Napoli
Zip:
80131
Country:
Italy
Status:
Not yet recruiting
Contact:
Last name:
Paolo Ascierto, MD
Phone:
+39 081 17770810
Email:
melanoma.immunoterapia@istitutotumori.na.it
Facility:
Name:
Fondazione Policlinico Gemelli IRCCS
Address:
City:
Roma
Zip:
00168
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Ernesto Rossi, MD
Phone:
+39 06 30156318
Email:
ernesto.rossi@policlinicogemelli.it
Facility:
Name:
AOUS Policlinico Le Scotte
Address:
City:
Siena
Zip:
53100
Country:
Italy
Status:
Not yet recruiting
Contact:
Last name:
Michele Maio, MD
Phone:
+39 0577586304
Email:
dh.immunonco@ao-siena.toscana.it
Facility:
Name:
LUMC (Leids Universitair Medisch Centrum)
Address:
City:
Leiden
Zip:
2333 ZA
Country:
Netherlands
Status:
Not yet recruiting
Contact:
Last name:
Ellen Kapiteijn, MD
Phone:
+31 (0)71 526 1093
Email:
h.w.kapiteijn@lumc.nl
Facility:
Name:
Ośrodek Badań Klinicznych Wczesnych Faz, Uniwersyteckie Centrum Kliniczne w Gdańsku
Address:
City:
Gdańsk
Zip:
80-214
Country:
Poland
Status:
Not yet recruiting
Contact:
Phone:
+48 58 584 44 66
Email:
obkwf@uck.gda.pl
Facility:
Name:
Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Państwowy Instytut Badawczy
Address:
City:
Warsaw
Zip:
02-781
Country:
Poland
Status:
Not yet recruiting
Contact:
Phone:
+48 22 546 21 03
Email:
badaniakliniczne@pib-nio.pl
Facility:
Name:
Catalan Institute of Oncology
Address:
City:
L'Hospitalet de Llobregat
Zip:
8908
Country:
Spain
Status:
Not yet recruiting
Contact:
Last name:
Josep Maria Piulats, MD
Phone:
+34 932607744
Email:
contactfortrialsICOLH@iconcologia.net
Facility:
Name:
Hospital Universitario La Paz
Address:
City:
Madrid
Zip:
28046
Country:
Spain
Status:
Not yet recruiting
Contact:
Last name:
Yolanda Alvarez, BSc
Email:
yolandalapaz@gmail.com
Facility:
Name:
Hospital Clínico Universitario de Santiago de Compostela
Address:
City:
Santiago de Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Estiban Mendez, Bsc
Phone:
+34 663 609 134
Email:
estiban.mendez.barrio@sergas.es
Facility:
Name:
Hospital Universitario Virgen Macarena
Address:
City:
Sevilla
Zip:
41009
Country:
Spain
Status:
Not yet recruiting
Contact:
Last name:
María del Carmen Álamo, MD
Phone:
+34 629 310 196 (611565)
Email:
alamodelagala@gmail.com
Contact backup:
Last name:
María Candón, SC
Phone:
+34 629 310 196 (611565)
Email:
mariacandon.oncomacarena@gmail.com
Facility:
Name:
Hospital General Universitario Valencia
Address:
City:
Valencia
Zip:
46014
Country:
Spain
Status:
Not yet recruiting
Contact:
Last name:
Alfonso Berrocal, MD
Phone:
+34 96 313 18 00
Phone ext:
437635
Email:
berrocal.alf@gmail.com
Contact backup:
Last name:
Iris Ramos
Phone:
+34 96 313 18 00
Phone ext:
437635
Email:
ramos_iri@gva.es
Facility:
Name:
Dermatologische Klinik, USZ Flughafen Geschoss 7 - Klinische Forschung
Address:
City:
Zuerich
Zip:
8058
Country:
Switzerland
Status:
Recruiting
Contact:
Last name:
Reinhard Dummer, Prof. Dr. med
Phone:
0041 44 255 25 88
Email:
reinhard.dummer@usz.ch
Facility:
Name:
The Beatson West of Scotland Cancer Centre
Address:
City:
Glasgow
Zip:
G12 0YN
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Ruth Orr
Phone:
00 44 (0) 141 301 7207
Email:
ruth.orr@glasgow.ac.uk
Facility:
Name:
Mount Vernon Cancer Centre East & North Herts NHS Trust
Address:
City:
Northwood
Zip:
HA6 2RN
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Paul Nathan, Prof. Dr. med.
Phone:
0333 332 5470
Email:
mvccresearch.enh-tr@nhs.net
Facility:
Name:
The Clatterbridge Cancer Centre NHS Foundation Trust
Address:
City:
Wirral
Zip:
CH63 4JY
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Joseph Sacco, Professor
Phone:
0151 556 5000
Email:
joseph.sacco@nhs.net
Start date:
October 31, 2023
Completion date:
January 15, 2028
Lead sponsor:
Agency:
IDEAYA Biosciences
Agency class:
Industry
Source:
IDEAYA Biosciences
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT05987332
