Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")

Trial Title: Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")

NCT ID: NCT06000527

Condition: Juvenile Recurrent Respiratory Papillomatosis

Conditions: Official terms:
Respiratory Tract Infections
Papillomavirus Infections
Papilloma
Recurrence

Study type: Observational

Overall status: Recruiting

Study design:

Time perspective: Prospective

Summary: Recurrent respiratory papillomatosis (RRP) is a rare disease. However, it is the most common benign laryngeal tumor in children. To date, no epidemiological data are available in France. The aim of this study is to establish the epidemiology of juvenile PPR.

Detailed description: Recurrent respiratory papillomatosis (RRP) is characterized by the recurrent proliferation of multiple polypoid squamous tumors in the respiratory tract, linked to HPV infection. RRP is a rare disease. However, it is the most common benign laryngeal tumor in children. There are currently no French national epidemiological data on this disease. The data collected by the reference centers will enable us to gain a better understanding of this pathology in terms of epidemiology, risk factors, genetic susceptibility and clinical manifestations, as well as to significantly study the efficacy of the various existing therapies and preventive measures, in order to establish a clear, standardized and optimal guideline.

Criteria for eligibility:

Study pop:
All patients with juvenile PRR in France

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: - Patients with juvenile PRR (disease onset before age 18) - Followed in the : - The MALO CRMR - One of the MALO network's CCMRs - One of the main correspondent centers Exclusion Criteria: - Patients objecting to the collection of their personal data - Parents of minor patients objecting to the collection of their child's personal data

Gender: All

Minimum age: N/A

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: hôpital Necker Enfants malades

Address:
City: Paris
Zip: 75015
Country: France

Status: Recruiting

Contact:
Last name: Nicolas Leboulanger

Phone: 0144494682
Email: nicolas.leboulanger@aphp.fr

Start date: October 1, 2022

Completion date: September 30, 2032

Lead sponsor:
Agency: Imagine Institute
Agency class: Other

Source: Imagine Institute

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT06000527