Trial Title:
OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
NCT ID:
NCT06016738
Condition:
Breast Cancer
Advanced Breast Cancer
Metastatic Breast Cancer
ER Positive Breast Cancer
HER2 Negative Breast Carcinoma
Conditions: Official terms:
Breast Neoplasms
Letrozole
Fulvestrant
Anastrozole
Exemestane
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Palazestrant
Description:
Participants will be treated with palazestrant once daily on a 4 week (28 day) cycle.
Doses evaluated in the dose-selection part will be 120 mg once daily and 90 mg once
daily.
Arm group label:
Palazestrant (OP-1250)
Other name:
OP-1250
Intervention type:
Drug
Intervention name:
Fulvestrant
Description:
Participants will be treated with fulvestrant on C1D1, C1D15, and then on Day 1 of every
subsequent 4 week (28 day) cycle
Arm group label:
Standard of Care Endocrine Therapy
Intervention type:
Drug
Intervention name:
Anastrozole
Description:
Participants will be treated with anastrozole once daily on a 4 week (28 day) cycle
Arm group label:
Standard of Care Endocrine Therapy
Intervention type:
Drug
Intervention name:
Letrozole
Description:
Participants will be treated with letrozole once daily on a 4 week (28 day) cycle
Arm group label:
Standard of Care Endocrine Therapy
Intervention type:
Drug
Intervention name:
Exemestane
Description:
Participants will be treated with exemestane once daily on a 4 week (28 day) cycle
Arm group label:
Standard of Care Endocrine Therapy
Summary:
This phase 3 clinical trial compares the safety and efficacy of palazestrant (OP-1250) to
the standard-of-care options of fulvestrant or an aromatase inhibitor in women and men
with breast cancer whose disease has advanced on one endocrine therapy in combination
with a CDK4/6 inhibitor.
Detailed description:
This is an international, multicenter, randomized, open-label, active-controlled, phase 3
clinical trial. The purpose of this trial is to compare the safety and efficacy of
palazestrant (OP-1250) as a single agent to the standard of care endocrine therapy:
either fulvestrant or an aromatase inhibitor (anastrozole, letrozole, or exemestane).
This trial is seeking adult participants with ER+, HER2- advanced or metastatic breast
cancer whose disease has relapsed or progressed on 1 or 2 prior lines of standard-of-care
endocrine therapy for metastatic breast cancer. Prior lines of therapy must include one
line of endocrine therapy in combination with a CDK 4/6 inhibitor. In the dose-selection
part of the trial, approximately 120 participants will be randomized to one of the two
doses of palazestrant or to the standard-of-care endocrine therapy. Thereafter,
approximately 390 participants will be randomized to palazestrant at the selected dose or
to the standard-of-care endocrine therapy.
Criteria for eligibility:
Criteria:
Key inclusion criteria:
- Adult female or male participants.
- ER+, HER2- locally advanced or metastatic breast cancer that is not amenable to
curative therapy.
- Evaluable disease (measurable disease or bone-only disease).
- Previously received a CDK4/6 inhibitor in combination with an endocrine therapy in
the advanced setting. One additional line of ET as a monotherapy is allowed.
Duration of the most recent prior ET must be at least 6 months.
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.
- Adequate hematologic, hepatic, and renal functions.
- Female participants can be pre-, peri- or postmenopausal.
- Male and pre- or peri-menopausal female participants must be willing to take a GnRH
(or LHRH) agonist.
Key exclusion criteria:
- Symptomatic visceral disease, imminent organ failure, or any other reason that makes
the participant ineligible for endocrine monotherapy.
- Previously received chemotherapy in the advanced/metastatic setting.
- Previously received treatment with elacestrant or an investigational estrogen
receptor-directed therapy.
- History of allergic reactions to study treatment.
- Any contraindications to the selected standard-of-care endocrine therapy in the
local prescribing information.
- Symptomatic central nervous system metastases, carcinomatous meningitis,
leptomeningeal disease, or a spinal cord compression that require immediate
treatment.
- Clinically significant comorbidities such as significant cardiac or cerebrovascular
disease, gastrointestinal disorders that could affect absorption of study treatment.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Clinical Trial Site
Address:
City:
Tucson
Zip:
85724
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Fountain Valley
Zip:
92708
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
La Jolla
Zip:
92093
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Los Angeles
Zip:
90027
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Whittier
Zip:
90602
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Aurora
Zip:
80045
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Denver
Zip:
80218
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Golden
Zip:
80401
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Grand Junction
Zip:
81505
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Danbury
Zip:
06810
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Newark
Zip:
19713
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trials Site
Address:
City:
Jacksonville
Zip:
32223
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Margate
Zip:
33063
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Orlando
Zip:
32804
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Plantation
Zip:
33324
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Tamarac
Zip:
33321
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Atlanta
Zip:
30322
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Chicago
Zip:
60616-2315
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Chicago
Zip:
60637
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Urbana
Zip:
61801
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Baton Rouge
Zip:
70809
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Baltimore
Zip:
21201
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Boston
Zip:
02111
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Saint Louis Park
Zip:
55426
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Lincoln
Zip:
68510-2496
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Farmington
Zip:
87401
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
New York
Zip:
10032
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Port Jefferson Station
Zip:
11776
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Dayton
Zip:
45409
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Toledo
Zip:
43623
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Portland
Zip:
97239
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Nashville
Zip:
37203
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Nashville
Zip:
37208
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Dallas
Zip:
75246
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Dallas
Zip:
75390
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Spokane
Zip:
99204
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Spokane
Zip:
99218
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
San Salvador De Jujuy
Zip:
4600
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Viedma
Zip:
R8500ACE
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Rosario
Zip:
S2013DTC
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Rosario
Zip:
S2013KDS
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
San Miguel De Tucumán
Zip:
4000
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Buenos Aires
Zip:
C14626ABP
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Córdoba
Zip:
X5000HHW
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Córdoba
Zip:
X5008HHW
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
La Rioja
Zip:
5300
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Gosford
Zip:
2250
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Westmead
Zip:
2145
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Adelaide
Zip:
5000
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Ballarat Central
Zip:
3355
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Clayton
Zip:
3168
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Shepparton
Zip:
3630
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Nedlands
Zip:
6009
Country:
Australia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Edegem
Zip:
2650
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Woluwe-Saint-Lambert
Zip:
1200
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Charleroi
Zip:
6000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Leuven
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Salvador
Zip:
40050-410
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Belo Horizonte
Zip:
30150-221
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Recife
Zip:
50070-480
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Porto Alegre
Zip:
90035-903
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Porto Alegre
Zip:
90050-170
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Itajaí
Zip:
88301-220
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Sorocaba
Zip:
18060-105
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Rio De Janeiro
Zip:
20560-120
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Panagyurishte
Zip:
4500
Country:
Bulgaria
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Sofia
Zip:
1407
Country:
Bulgaria
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Vratsa
Zip:
3000
Country:
Bulgaria
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Calgary
Zip:
T2N 4N2
Country:
Canada
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Montréal
Zip:
H4A 3J1
Country:
Canada
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Hradec Králové
Zip:
500 12
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Nový Jičín
Zip:
741 01
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Olomouc
Zip:
799 00
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Bourg-en-Bresse
Zip:
01012
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Besançon
Zip:
25030
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Nantes
Zip:
44805
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Compiègne
Zip:
60200
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Clermont-Ferrand
Zip:
63011
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Le Mans
Zip:
72015
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Villejuif
Zip:
94085
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Montpellier
Zip:
34070
Country:
France
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Karlsruhe
Zip:
76135
Country:
Germany
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Krefeld
Zip:
47805
Country:
Germany
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Velbert
Zip:
42551
Country:
Germany
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Dresden
Zip:
01307
Country:
Germany
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Central
Zip:
100176
Country:
Hong Kong
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Central
Zip:
999077
Country:
Hong Kong
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Hong Kong
Zip:
999077
Country:
Hong Kong
Status:
Recruiting
Facility:
Name:
Clinical Trials Site
Address:
City:
Hong Kong
Zip:
999077
Country:
Hong Kong
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Kowloon
Zip:
999077
Country:
Hong Kong
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Pécs
Zip:
7624
Country:
Hungary
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Kecskemét
Zip:
6000
Country:
Hungary
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Debrecen
Zip:
4032
Country:
Hungary
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Avellino
Zip:
83100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Bologna
Zip:
40138
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Meldola
Zip:
47014
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Modena
Zip:
41124
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Reggio Emilia
Zip:
42100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Udine
Zip:
33100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Roma
Zip:
00144
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Roma
Zip:
00168
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Milano
Zip:
20141
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Rozzano
Zip:
20089
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Alessandria
Zip:
15121
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Pavia
Zip:
27100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Suwon-si
Zip:
16247
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Busan
Zip:
49201
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
2841
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
3080
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
3722
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
5505
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
6273
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
6591
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Seoul
Zip:
8308
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Suwon
Zip:
16499
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Clinical Trials Site
Address:
City:
Sungai Petani
Zip:
8000
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Kota Bharu
Zip:
16150
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
George Town
Zip:
10450
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Ipoh
Zip:
30450
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Putrajaya
Zip:
62250
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Kuching
Zip:
93586
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Petaling Jaya
Zip:
46050
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Kuala Lumpur
Zip:
59100
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Zapopan
Zip:
45070
Country:
Mexico
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Monterrey
Zip:
64116
Country:
Mexico
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Oaxaca
Zip:
68020
Country:
Mexico
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Sinaloa
Zip:
80230
Country:
Mexico
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Rotterdam
Zip:
3083 AN
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Łódź
Zip:
90-349
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Otwock
Zip:
05-400
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Brzozów
Zip:
36-200
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Rzeszów
Zip:
35-922
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Gdynia
Zip:
81-519
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Skórzewo
Zip:
60-185
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Wrocław
Zip:
50-450
Country:
Poland
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Matosinhos
Zip:
4454-509
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Coimbra
Zip:
3000-075
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Lisboa
Zip:
1099-023
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Lisboa
Zip:
1500-473
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Porto
Zip:
4050-428
Country:
Portugal
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Mayaguez
Zip:
00682-6391
Country:
Puerto Rico
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Oradea
Zip:
410469
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
București
Zip:
014141
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Cluj-Napoca
Zip:
400015
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Craiova
Zip:
200385
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Timisoara
Zip:
300239
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Brașov
Zip:
500152
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Iași
Zip:
700106
Country:
Romania
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Pamplona
Zip:
31008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Alicante
Zip:
03015
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Badajoz
Zip:
06080
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
León
Zip:
24071
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Lleida
Zip:
25198
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Madrid
Zip:
28033
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Madrid
Zip:
28050
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Santiago De Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Valencia
Zip:
46010
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Changhua
Zip:
500
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Kaohsiung
Zip:
80756
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Taichung
Zip:
40447
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Taichung
Zip:
433
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Tainan City
Zip:
736
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Taipei city
Zip:
111
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Taipei city
Zip:
114
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Taipei
Zip:
100
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Taipei
Zip:
11217
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Bangkok
Zip:
10300
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Bangkok
Zip:
10330
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Bangkok
Zip:
10700
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Chiang Mai
Zip:
50180
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Samut Sakhon
Zip:
74120
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
Songkhla
Zip:
90110
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Clinical Trial Site
Address:
City:
London
Zip:
EC1M 6BQ
Country:
United Kingdom
Status:
Recruiting
Start date:
November 16, 2023
Completion date:
September 30, 2027
Lead sponsor:
Agency:
Olema Pharmaceuticals, Inc.
Agency class:
Industry
Source:
Olema Pharmaceuticals, Inc.
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06016738
https://olema.com/science/publications
