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Trial Title: Early Detection of Lung Cancer In Patients With Chronic Chest Diseases

NCT ID: NCT06074978

Condition: Chest--Diseases

Study type: Observational

Overall status: Not yet recruiting

Study design:

Time perspective: Prospective

Summary: - To evaluate the effectiveness of LDCT in detecting early-stage lung cancer in patients with chronic lung conditions compared to standard chest x-rays. - To improve lung cancer outcomes through optimized use of radiological technologies for early detection in high-risk patients with pre-existing lung conditions.

Detailed description: The early detection of lung cancer is crucial, as it is one of the most common and deadly types of cancer worldwide. Early detection is especially important in patients with chronic chest diseases, as these underlying conditions can make lung cancer more difficult to diagnose at later stages. Radiological imaging techniques play a key role in the early detection of lung cancer in this high-risk patient population. Recent advances in imaging technologies have improved our ability to detect small lung abnormalities indicative of cancer at earlier stages, even before symptoms appear . Techniques such as low-dose CT scanning have been shown to reduce lung cancer mortality by up to 20% compared to chest radiography alone . Advanced imaging allows clinicians to identify subtle nodules or masses in the lungs that may represent cancer . Determining the type, size, and extent of lung lesions is important for prognosis and treatment planning . Imaging technologies help characterize lesions as benign or malignant and determine cancer stage . This information guides decisions around surgery, chemotherapy, radiation therapy, or other interventions . Early detection through radiological screening has been associated with improved survival rates for lung cancer patients with chronic lung diseases . Screening finds a higher portion of early-stage, potentially curable cancers in this high-risk group . Overall, advanced imaging techniques play a vital role in the early detection and management of lung cancer in patients with underlying chronic chest conditions.

Criteria for eligibility:

Study pop:
After taking the informed consent, full history was taken from all patients participating in the study. Detailed clinical examination and routine laboratory investigations (complete blood count, liver function test, urea, creatinine and ESR) will be done. - Radiological imaging technologies -Low Dose Computed tomography (CT scans), chest x-rays These are used to detect and characterize lung abnormalities. - Pulmonary function tests - Spirometry volume measurements, diffusion capacity testing. These assess lung health and function in patients with chronic lung conditions

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: 1- Chronic chest diseases Patients . Exclusion Criteria: 1 - Age: less than 45 years. 2-Patients diagnosed with lung cancer 3-Unstable patients or need for ICU admission

Gender: All

Minimum age: 45 Years

Maximum age: 75 Years

Healthy volunteers: No

Start date: December 20, 2023

Completion date: December 20, 2024

Lead sponsor:
Agency: Assiut University
Agency class: Other

Source: Assiut University

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT06074978

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