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Trial Title:
Unravelling Tumour Biology In Ovarian Cancer With Precision Imaging
NCT ID:
NCT06084195
Condition:
High Grade Serous Ovarian Cancer
Conditions: Official terms:
Ovarian Neoplasms
Carcinoma, Ovarian Epithelial
Conditions: Keywords:
Radiomics
Ovarian cancer
Genomics
Proteomics
Immune Tumor Microenvironment
Study type:
Interventional
Study phase:
N/A
Overall status:
Recruiting
Study design:
Allocation:
N/A
Intervention model:
Single Group Assignment
Primary purpose:
Other
Masking:
None (Open Label)
Intervention:
Intervention type:
Biological
Intervention name:
Blood sample and tissue sample
Description:
During the surgery :
- Tissus sample : primary tumor and metastasis
- blood sample : 3 EDTA tubes
- ex vivo MRI data
Arm group label:
Single arm
Summary:
The objective of this study is to explore the integration of in vivo and ex vivo of MRI
with histology and molecular assessments to advance non-invasive characterization of
tumor heterogeneity in high-grade serous ovarian cance
Detailed description:
After being informed about the study and potential risks, all patient giving wirtting
informed consent.
During surgery, tissue and blood samples will be conserved for the study. In this study
will be compared images obtained in vivo before surgical management, ex vivo images
obtained on excised tissues during surgery, histological data obtained during surgery.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Patient aged >18
- Pathologically proven HGSOC at an advanced stage (FIGO IIIB or IIIC) which can
benefit from surgery with or without prior neoadjuvant treatment
- Willingness and ability to comply with planned visits, treatment plan, laboratory
tests and other study procedures,
- Patient who has given informed, written and express consent,
- Patient affiliated with a French health insurance scheme.
Exclusion Criteria:
- Early-stage disease (FIGO
Gender:
Female
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
NOUGARET Stephanie
Address:
City:
Montpellier
Zip:
34298
Country:
France
Status:
Recruiting
Contact:
Last name:
NOUGARET Stephanie, MD
Email:
stephanie.nougaret@icm.unicancer.fr
Start date:
December 19, 2023
Completion date:
October 2029
Lead sponsor:
Agency:
Institut du Cancer de Montpellier - Val d'Aurelle
Agency class:
Other
Source:
Institut du Cancer de Montpellier - Val d'Aurelle
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06084195
