Trial Title:
A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Patients With Previously Untreated Diffuse Large B-cell Lymphoma
NCT ID:
NCT06091865
Condition:
Diffuse Large B-cell Lymphoma (DLBCL)
Conditions: Official terms:
Lymphoma
Lymphoma, B-Cell
Lymphoma, Large B-Cell, Diffuse
Prednisone
Prednisolone
Cyclophosphamide
Rituximab
Doxorubicin
Vincristine
Conditions: Keywords:
Non-Hodgkin lymphomas (NHL)
B-cell non-Hodgkin lymphomas (B-NHL)
Diffuse Large B-cell Lymphoma
Odronextamab
Anti-CD20 × anti-CD3 bispecific antibody
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Odronextamab
Description:
Odronextamab will be administered by intravenous (IV) infusion
Arm group label:
Odronextamab + CHOP
Other name:
REGN1979
Intervention type:
Drug
Intervention name:
Rituximab
Description:
Rituximab will be administered IV, or subcutaneously (SC)
Arm group label:
Rituximab + CHOP
Other name:
Rituxan
Intervention type:
Drug
Intervention name:
Cyclophosphamide
Description:
Cyclophosphamide will be administered IV as part of chemotherapy
Arm group label:
Odronextamab + CHOP
Arm group label:
Rituximab + CHOP
Other name:
Cytoxan
Intervention type:
Drug
Intervention name:
Doxorubicin
Description:
Doxorubicin will be administered IV as part of chemotherapy
Arm group label:
Odronextamab + CHOP
Arm group label:
Rituximab + CHOP
Other name:
Adriamycin
Intervention type:
Drug
Intervention name:
Vincristine
Description:
Vincristine will be administered IV as part of chemotherapy
Arm group label:
Odronextamab + CHOP
Arm group label:
Rituximab + CHOP
Other name:
Oncovin
Intervention type:
Drug
Intervention name:
Prednisone/Prednisolone
Description:
Prednisone or prednisolone will be administered orally (PO) as part of chemotherapy
Arm group label:
Odronextamab + CHOP
Arm group label:
Rituximab + CHOP
Other name:
Deltasone/Omnipred
Summary:
This study is researching an experimental drug called odronextamab, referred to as study
drug, when used in combination with chemotherapy. The study is focused on patients with
diffuse large B-cell lymphoma (DLBCL) that have not been treated before (called
"previously untreated"). Patients with DLBCL that have come back after treatment (called
"relapsed"), or have not responded to treatment (called "refractory"), can also
participate in this study.
This study will be made up of Part 1A, Part 1B, and Part 2.The aim of Part 1A and Part 1B
of the study is to see how safe and tolerable the study drug in combination with
chemotherapy is and to determine the dose and schedule of the study drug to be combined
with chemotherapy in Part 2 of the study.
The aim of Part 2 of the study is to see how effective the combination of the study drug
with chemotherapy is in comparison with the combination of rituximab (the comparator
drug), and chemotherapy, the current standard of care treatment approved for DLBCL.
Standard of care means the usual medication expected and used when receiving treatment
for a condition.
The study is looking at several other research questions, including:
- What side effects may happen from taking the study drug when combined with
chemotherapy
- How much study drug is in the blood at different times
- Whether the body makes antibodies against the study drug (which could make the study
drug less effective or could lead to side effects)
- The impact from the study drug on quality of life and ability to complete routine
daily activities
Criteria for eligibility:
Criteria:
KEY Inclusion Criteria:
1. Previously untreated participants for lymphoma with documented cluster of
differentiation 20+ (CD20+) DLBCL, as described in the protocol OR relapsed or
refractory DLBCL, for whom next available standard of care therapy is not available
or deemed ineligible according to the investigator (Part 1A only)
2. Measurable disease with at least one nodal lesion or at least one extranodal lesion,
as described in the protocol
3. Eastern Cooperative Oncology Group (ECOG) performance status ≤2
4. Life expectancy ≥ 12 months
5. International Prognostic Index (IPI) of 3 to 5 (part 1 only) and ≥2 (part 2) for
untreated DLBCL only;
6. Adequate hematologic and organ function, as defined in the protocol.
KEY Exclusion Criteria:
1. Primary central nervous system (CNS) lymphoma or known involvement by non-primary
CNS NHL and history or current relevant CNS pathology
2. Another active malignancy, significant active disease or medical condition, as
described in the protocol
3. Peripheral neuropathy Grade ≥3
4. Treatment with any systemic anti-lymphoma therapy, except for participants with
relapsed/refractory (R/R) DLBCL and participants with DLBCL transformed from an
indolent follicular lymphoma after treatment with systemic anti-lymphoma therapy.
5. Any other therapy or investigational treatment within 28 days or 5 half-lives of the
drug, whichever is shorter, prior to the start of study treatment
6. Recent major surgery, prior organ transplantation, or standard radiotherapy, as
described in the protocol
7. Allergy/hypersensitivity to study drugs, as described in the protocol
8. Infections such as any active infection (bacterial, viral, fungal, mycobacterial,
parasitic or other), active Coronavirus disease (COVID-19) infection, uncontrolled
infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV), or
hepatitis C virus (HCV), Cytomegalovirus (CMV) infection, as described in the
protocol.
Note: Other protocol-defined Inclusion/ Exclusion criteria apply
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
David Geffen School of Medicine at UCLA
Address:
City:
Los Angeles
Zip:
90095
Country:
United States
Status:
Recruiting
Facility:
Name:
UC Irvine Health Chao Family Comprehensive Cancer Center
Address:
City:
Orange
Zip:
92868
Country:
United States
Status:
Recruiting
Facility:
Name:
University of California (UC) Davis
Address:
City:
Sacramento
Zip:
95817
Country:
United States
Status:
Recruiting
Facility:
Name:
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Address:
City:
Indianapolis
Zip:
46202
Country:
United States
Status:
Recruiting
Facility:
Name:
St. Vincent Ascension - Peyton Manning Children's Hospital
Address:
City:
Indianapolis
Zip:
46260
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Research of Indiana
Address:
City:
Noblesville
Zip:
46062
Country:
United States
Status:
Recruiting
Facility:
Name:
University of Kentucky
Address:
City:
Lexington
Zip:
40536
Country:
United States
Status:
Recruiting
Facility:
Name:
Beth Israel Deaconess Medical Center
Address:
City:
Boston
Zip:
02215
Country:
United States
Status:
Recruiting
Facility:
Name:
Henry Ford Hospital
Address:
City:
Detroit
Zip:
48202
Country:
United States
Status:
Recruiting
Facility:
Name:
Cancer and Hematology Centers of Western Michigan
Address:
City:
Grand Rapids
Zip:
49503
Country:
United States
Status:
Recruiting
Facility:
Name:
Rutgers Cancer Institute of New Jersey
Address:
City:
New Brunswick
Zip:
08901
Country:
United States
Status:
Recruiting
Investigator:
Last name:
Matthew Matasar
Email:
Principal Investigator
Facility:
Name:
Stony Brook University Hospital
Address:
City:
Stony Brook
Zip:
11794
Country:
United States
Status:
Recruiting
Facility:
Name:
Clinical Research Alliance Inc
Address:
City:
Westbury
Zip:
11590
Country:
United States
Status:
Recruiting
Facility:
Name:
Duke University Medical Center
Address:
City:
Durham
Zip:
27710
Country:
United States
Status:
Recruiting
Facility:
Name:
University Hospitals Cleveland Medical Center
Address:
City:
Cleveland
Zip:
44106
Country:
United States
Status:
Recruiting
Facility:
Name:
Center For Oncology and Blood Disorders
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Facility:
Name:
The Community Cancer Trials
Address:
City:
Ogden
Zip:
84405
Country:
United States
Status:
Recruiting
Facility:
Name:
ProHealth Care Inc
Address:
City:
Waukesha
Zip:
53188
Country:
United States
Status:
Recruiting
Investigator:
Last name:
Timothy Wassenaar
Email:
Principal Investigator
Facility:
Name:
Liverpool Hospital
Address:
City:
Liverpool
Zip:
2170
Country:
Australia
Status:
Recruiting
Facility:
Name:
Calvary Mater Newcastle
Address:
City:
Waratah
Zip:
2298
Country:
Australia
Status:
Recruiting
Facility:
Name:
Icon Cancer Centre
Address:
City:
Auchenflower
Zip:
4066
Country:
Australia
Status:
Recruiting
Facility:
Name:
Pindara Private Hospital
Address:
City:
Benowa
Zip:
4217
Country:
Australia
Status:
Recruiting
Facility:
Name:
Epworth Freemasons
Address:
City:
East Melbourne
Zip:
3121
Country:
Australia
Status:
Recruiting
Facility:
Name:
Landeskrankenhaus Hochsteiermark
Address:
City:
Leoben
Zip:
8700
Country:
Austria
Status:
Recruiting
Facility:
Name:
Kepler University Hospital
Address:
City:
Linz
Zip:
4020
Country:
Austria
Status:
Recruiting
Facility:
Name:
Medical University Graz
Address:
City:
Graz
Zip:
8036
Country:
Austria
Status:
Recruiting
Facility:
Name:
Medical University of Vienna
Address:
City:
Vienna
Zip:
1090
Country:
Austria
Status:
Recruiting
Facility:
Name:
Hanusch Krankenhaus
Address:
City:
Vienna
Zip:
1140
Country:
Austria
Status:
Recruiting
Facility:
Name:
Klinikum Wels-Grieskirchen GmbH
Address:
City:
Wels
Zip:
4600
Country:
Austria
Status:
Recruiting
Facility:
Name:
Universitair Ziekenhuis (UZ) Gent/ Ghent University Hospital
Address:
City:
Gent
Zip:
9000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
AZ Delta
Address:
City:
Roeselare
Zip:
8800
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Institut Jules Bordet
Address:
City:
Brussels
Zip:
1000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Az st Elizabeth
Address:
City:
Herentals
Zip:
2200
Country:
Belgium
Status:
Recruiting
Facility:
Name:
CHR de Verviers
Address:
City:
Verviers
Zip:
4800
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Hospital Clinico Universidad de Los Andes
Address:
City:
Santiago
Zip:
7620157
Country:
Chile
Status:
Recruiting
Facility:
Name:
Inmunocel
Address:
City:
Santiago
Zip:
7580206
Country:
Chile
Status:
Recruiting
Facility:
Name:
Clinica Alemana de Santiago
Address:
City:
Santiago
Zip:
7650568
Country:
Chile
Status:
Recruiting
Facility:
Name:
University Hospital Hradec Kralove
Address:
City:
Hradec Kralove 5
Zip:
50005
Country:
Czechia
Status:
Recruiting
Facility:
Name:
University Hospital Kralovske Vinohrady
Address:
City:
Prague
Zip:
10034
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Vseobecna fakultni nemocnice v Praze
Address:
City:
Praha
Zip:
12808
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Centre Hospitalier Universitaire (CHU) Rennes
Address:
City:
Rennes
Zip:
35033
Country:
France
Status:
Recruiting
Facility:
Name:
CHRU de Tours
Address:
City:
Tours
Zip:
37044
Country:
France
Status:
Recruiting
Facility:
Name:
Polyclinique Bordeaux Nord Aquitaine
Address:
City:
Bordeaux Cedex
Zip:
33077
Country:
France
Status:
Recruiting
Facility:
Name:
Hôpital Saint Vincent-de-Paul
Address:
City:
Lille cedex
Zip:
5900
Country:
France
Status:
Recruiting
Facility:
Name:
CHU de Poitiers
Address:
City:
Poitiers
Zip:
86000
Country:
France
Status:
Recruiting
Facility:
Name:
Centre Hospitalier Universitaire (CHU) de Bordeaux
Address:
City:
Pessac
Zip:
F33600
Country:
France
Status:
Recruiting
Facility:
Name:
Gustave Roussy
Address:
City:
Villejuif
Zip:
94800
Country:
France
Status:
Recruiting
Facility:
Name:
Centre Hospitalier Metropole Savoie
Address:
City:
Chambery
Zip:
73000
Country:
France
Status:
Recruiting
Facility:
Name:
Centre Hospitalier Universitaire Angers (CHU Angers)
Address:
City:
Angers
Zip:
49933
Country:
France
Status:
Recruiting
Facility:
Name:
Change Annecy
Address:
City:
Metz Tessy
Zip:
74374
Country:
France
Status:
Recruiting
Facility:
Name:
Nantes University Hospital
Address:
City:
Nantes
Zip:
44093
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Nimes Institut de Cancerologie
Address:
City:
Nimes
Zip:
30029
Country:
France
Status:
Recruiting
Facility:
Name:
Saint Antoine Hospital
Address:
City:
Paris
Zip:
75571
Country:
France
Status:
Recruiting
Facility:
Name:
CHU de Saint-Etienne
Address:
City:
Saint-Etienne
Zip:
42055
Country:
France
Status:
Recruiting
Facility:
Name:
Hopital Victor Dupouy Argenteuil
Address:
City:
Argenteuil
Zip:
95100
Country:
France
Status:
Recruiting
Facility:
Name:
University Hospital Essen
Address:
City:
Essen
Zip:
45127
Country:
Germany
Status:
Recruiting
Facility:
Name:
Hematological Praxis Dresden
Address:
City:
Dresden
Zip:
01307
Country:
Germany
Status:
Recruiting
Facility:
Name:
University Hospital, Medical Dept. I
Address:
City:
Dresden
Zip:
01307
Country:
Germany
Status:
Recruiting
Facility:
Name:
Stadtisches Krankenhaus Kiel
Address:
City:
Kiel
Zip:
24116
Country:
Germany
Status:
Recruiting
Facility:
Name:
University Medical Center of Mainz
Address:
City:
Mainz
Zip:
55131
Country:
Germany
Status:
Recruiting
Facility:
Name:
Clinic Frankfurt (Oder)
Address:
City:
Oder
Zip:
15236
Country:
Germany
Status:
Recruiting
Facility:
Name:
St James Hospital and Trinity College Dublin
Address:
City:
Dublin
Zip:
D08
Country:
Ireland
Status:
Recruiting
Facility:
Name:
Beaumont Hospital
Address:
City:
Dublin
Zip:
D09 V2N0
Country:
Ireland
Status:
Recruiting
Facility:
Name:
Samson Assuta Ashdod University Hospital
Address:
City:
Ashdod
Zip:
7747629
Country:
Israel
Status:
Recruiting
Facility:
Name:
Bnai Zion Medical Center
Address:
City:
Haifa
Zip:
31048
Country:
Israel
Status:
Recruiting
Facility:
Name:
Hadassah Medical Center
Address:
City:
Jerusalem
Zip:
91200
Country:
Israel
Status:
Recruiting
Facility:
Name:
Galilee Medical Center
Address:
City:
Nahariya
Zip:
22100
Country:
Israel
Status:
Recruiting
Facility:
Name:
The Chaim Sheba Medical Center
Address:
City:
Ramat Gan
Zip:
5262000
Country:
Israel
Status:
Recruiting
Facility:
Name:
The Tel Aviv Sourasky Medical Center
Address:
City:
Tel Aviv
Zip:
64239
Country:
Israel
Status:
Recruiting
Facility:
Name:
Istituto Scientifico Romagnolo per lo Studio e la Cura dei tumori
Address:
City:
Meldola (fc)
Zip:
47014
Country:
Italy
Status:
Recruiting
Facility:
Name:
Istituto Europeo di Oncologia
Address:
City:
Milano
Zip:
20141
Country:
Italy
Status:
Recruiting
Facility:
Name:
A.O.U. di Modena
Address:
City:
Modena
Zip:
41124
Country:
Italy
Status:
Recruiting
Facility:
Name:
ASST Monza Ospedale San Gerardo
Address:
City:
Monza
Zip:
20900
Country:
Italy
Status:
Recruiting
Facility:
Name:
Federico II University
Address:
City:
Napoli
Zip:
80128
Country:
Italy
Status:
Recruiting
Facility:
Name:
Azienda Ospedaliero Universitaria Maggiore della Carita
Address:
City:
Novara
Zip:
28100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Fondazione IRCCS Policlinico San Matteo
Address:
City:
Pavia
Zip:
27100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Azienda Ospedaliera di Perugia
Address:
City:
Perugia
Zip:
06132
Country:
Italy
Status:
Recruiting
Facility:
Name:
Ospedale Santa Maria delle Croci
Address:
City:
Ravenna
Zip:
48121
Country:
Italy
Status:
Recruiting
Facility:
Name:
Azienda Ospedaliero-Universitaria (AOU) Città della Salute e della Scienza di Torino
Address:
City:
Torino
Zip:
10126
Country:
Italy
Status:
Recruiting
Facility:
Name:
Hematology Clinic, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC)
Address:
City:
Udine
Zip:
33100
Country:
Italy
Status:
Recruiting
Facility:
Name:
St. Vincent Hospital, The Catholic University of Korea
Address:
City:
Suwon-si
Zip:
16247
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Inje University Busan Paik Hospital
Address:
City:
Busan
Zip:
47392
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Dong-A University Hospital
Address:
City:
Busan
Zip:
49201
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Pusan National University Hospital
Address:
City:
Busan
Zip:
49241
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Yeyungnam University Medical Center
Address:
City:
Daegu
Zip:
42415
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Keimyung University Dongsan Hospital
Address:
City:
Daegu
Zip:
42601
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Gachon University Gil Medical Center
Address:
City:
Incheon
Zip:
21565
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Asan Medical Center
Address:
City:
Seoul
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Seoul st mary's hospital
Address:
City:
Seoul
Zip:
06591
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
The Catholic University of Korea
Address:
City:
Seoul
Zip:
137-701
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Samsung Medical Center
Address:
City:
Seoul
Zip:
6351
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Hospital Tg Ampuan Afzan
Address:
City:
Kuantan
Zip:
25100
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Hospital Queen Elizabeth
Address:
City:
Kota Kinabalu
Zip:
88200
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Subang Jaya Medical Center
Address:
City:
Subang Jaya
Zip:
47500
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
University Malaya Medical Centre
Address:
City:
Kuala Lumpur
Zip:
49100
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Hospital Ampang
Address:
City:
Ampang
Zip:
68000
Country:
Malaysia
Status:
Recruiting
Facility:
Name:
Malopolskie Centrum Medyczne
Address:
City:
Krakow
Zip:
30-510
Country:
Poland
Status:
Recruiting
Facility:
Name:
Uniwersyteckie Centrum Kliniczne
Address:
City:
Gdansk
Zip:
80-214
Country:
Poland
Status:
Recruiting
Facility:
Name:
Pratia Poznan Medical Center
Address:
City:
Poznan
Zip:
60185
Country:
Poland
Status:
Recruiting
Facility:
Name:
Szpital Uniwersytecki Nr2 Bydgoszcz
Address:
City:
Bydgoszcz
Zip:
85-168
Country:
Poland
Status:
Recruiting
Facility:
Name:
Szpital Szpecjalistyczny w Walbrzychu
Address:
City:
Walbrzych
Zip:
58-300
Country:
Poland
Status:
Recruiting
Facility:
Name:
National University Hospital Singapore
Address:
City:
Singapore
Zip:
119074
Country:
Singapore
Status:
Recruiting
Facility:
Name:
National Cancer Centre of Singapore
Address:
City:
Singapore
Zip:
168582
Country:
Singapore
Status:
Recruiting
Facility:
Name:
Tan Tock Seng Hospital
Address:
City:
Singapore
Zip:
308433
Country:
Singapore
Status:
Recruiting
Facility:
Name:
Hospital Clinico Universitario Santiago de Compostela
Address:
City:
Santiago de Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Central De Asturias
Address:
City:
Oviedo
Zip:
33011
Country:
Spain
Status:
Recruiting
Facility:
Name:
Son Espases University Hospital
Address:
City:
Palma
Zip:
07120
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitari Parc Tauli
Address:
City:
Sabadell
Zip:
08208
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitari Mutua Terrassa
Address:
City:
Terrassa
Zip:
08221
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Marques de Valdecilla
Address:
City:
Santander
Zip:
39008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Quironsalud Madrid
Address:
City:
Pozuelo de Alarcón
Zip:
28223
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Sant Pau
Address:
City:
Barcelona
Zip:
08041
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Virgen de Las Nieves de Granada
Address:
City:
Granada
Zip:
18014
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Infanta Leonor
Address:
City:
Madrid
Zip:
28031
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Ramon y Cajal
Address:
City:
Madrid
Zip:
28034
Country:
Spain
Status:
Recruiting
Facility:
Name:
Fundacion Jimenez Diaz University Hospital
Address:
City:
Madrid
Zip:
28040
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario HM Sanchinarro
Address:
City:
Madrid
Zip:
28050
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital Universitario Virgen del Rocio
Address:
City:
Sevilla
Zip:
41013
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hospital General Universitario de Toledo
Address:
City:
Toledo
Zip:
45007
Country:
Spain
Status:
Recruiting
Facility:
Name:
Instituto Valenciano de Oncologia
Address:
City:
Valencia
Zip:
46009
Country:
Spain
Status:
Recruiting
Facility:
Name:
University Hospital Doctor Peset
Address:
City:
Valencia
Zip:
46017
Country:
Spain
Status:
Recruiting
Facility:
Name:
Chiayi Chang Gung Memorial Hospital
Address:
City:
Puzi
Zip:
613
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Changhua Christian Hospital
Address:
City:
Changhua City
Zip:
50006
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Taipei Medical University - Shuang Ho Hospital
Address:
City:
New Taipei City
Zip:
23561
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Wanfang Hospital
Address:
City:
Taipei
Zip:
00116
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Chang Gung Memorial Hospital- Linkou Branch
Address:
City:
Taoyuan
Zip:
333
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Chulalongkorn University
Address:
City:
Bangkok
Zip:
10330
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Sriraj Hospital
Address:
City:
Bangkok
Zip:
10700
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Chiang Mai University
Address:
City:
Chiang Mai
Zip:
50200
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Khon Kaen University
Address:
City:
Khon Kaen
Zip:
40002
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
Address:
City:
Yenimahalle
Zip:
06200
Country:
Turkey
Status:
Recruiting
Investigator:
Last name:
Fevzi Altuntas
Email:
Principal Investigator
Facility:
Name:
VM Medical Park Mersin Hospital
Address:
City:
Mezitli
Zip:
33200
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Tekirdag Namik Kemal University Hospital
Address:
City:
Tekirdag
Zip:
59100
Country:
Turkey
Status:
Recruiting
Investigator:
Last name:
Burhan Turgut
Email:
Principal Investigator
Facility:
Name:
Gazi Universitesi
Address:
City:
Besevler
Zip:
6500
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Istanbul University, Istanbul Faculty of Medicine
Address:
City:
Istanbul
Zip:
34418
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Ege University
Address:
City:
Izmir
Zip:
35100
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Dokuz Eylul University
Address:
City:
Izmir
Zip:
35340
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Sakarya University Medical Faculty Hematology Department
Address:
City:
Sakarya
Zip:
54290
Country:
Turkey
Status:
Recruiting
Investigator:
Last name:
Tuba Hacibekiroglu
Email:
Principal Investigator
Facility:
Name:
Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
Address:
City:
Samsun
Zip:
55239
Country:
Turkey
Status:
Recruiting
Facility:
Name:
NHS Grampian: Aberdeen Royal Infirmary
Address:
City:
Aberdeen
Zip:
AB25 2ZN
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
The Hillingdon Hospitals NHS Foundation Trust
Address:
City:
Uxbridge
Zip:
UB8 3NN
Country:
United Kingdom
Status:
Recruiting
Start date:
December 13, 2023
Completion date:
September 18, 2028
Lead sponsor:
Agency:
Regeneron Pharmaceuticals
Agency class:
Industry
Source:
Regeneron Pharmaceuticals
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06091865
