Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum

Trial Title: Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum

NCT ID: NCT06096493

Condition: Rectal Cancer

Conditions: Official terms:
Rectal Neoplasms
Recurrence

Conditions: Keywords:
cancer rectum
recurrence
disease free survival

Study type: Observational

Overall status: Recruiting

Study design:

Time perspective: Retrospective

Intervention:

Intervention type: Procedure
Intervention name: curative surgery for cancer rectum
Description: Curative surgery for cancer rectum.
Arm group label: Patients with cancer rectum underwent curative surgery

Summary: Tumor recurrence after curative surgical resection for rectal cancer is a serious complication that greatly affects the overall morbidity and the outcome. This study aims to identify the different prognostic factors affecting recurrence and disease-free survival after surgery.

Detailed description: A retrospective analysis of patients operated for cancer rectum with curative intent from. Exclusion criteria will include patients with familial adenomatous polyposis, multiple synchronous or metachronous rectal cancers, and death within 3 months. Incomplete patients' files and patients that lost follow-up will be excluded. Demographic, histopathological, follow up and outcome data will be collected from completed patients' files. Demographics include age, gender, family history, and chief complaint at the presentation. Histopathological data include tumor grade, vascular-perineural invasion, the total number of lymph nodes removed, and positive lymph nodes. Lymph node ratio will be defined as the ratio of positive lymph nodes to the total number of retrieved lymph nodes in a histopathology specimen. Disease-free survival will be calculated for each patient based on the time of surgery to the time of recurrence detection.

Criteria for eligibility:

Study pop:
- Patients who had curative surgery for cancer rectum.

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: - Patients who had curative surgery for cancer rectum. Exclusion Criteria: - Patients with familial adenomatous polyposis (FAP), multiple synchronous or metachronous rectal cancers, and death within 3 months - Patients that lost follow-up will be excluded.

Gender: All

Minimum age: 18 Years

Maximum age: 90 Years

Locations:

Facility:
Name: Qena Faculty of Medicine, South Valley University Hospitals

Address:
City: Qinā
Country: Egypt

Status: Recruiting

Contact:
Last name: Abdallah M Taha, MD

Phone: +201011617497
Email: abdallahsurgery@med.svu.edu.eg

Investigator:
Last name: Abdallah M Taha, MD
Email: Principal Investigator

Start date: May 1, 2023

Completion date: December 2023

Lead sponsor:
Agency: South Valley University
Agency class: Other

Source: South Valley University

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT06096493