Colonoscopy Check-up in People With Lynch Syndrome

Trial Title: Colonoscopy Check-up in People With Lynch Syndrome

NCT ID: NCT06126120

Condition: Lynch Syndrome

Conditions: Official terms:
Colorectal Neoplasms, Hereditary Nonpolyposis
Syndrome

Conditions: Keywords:
Lynch Syndrome
Colonoscopy
Surveillance

Study type: Observational

Overall status: Enrolling by invitation

Study design:

Time perspective: Cross-Sectional

Summary: Lynch Syndrome, an inherited condition, increases bowel cancer risk. People with Lynch Syndrome are recommended to have regular colonoscopies where a camera in a tube is used to look inside the bowel for cancer and for polyps (growths that sometimes can become cancerous). UK guidelines recommend that people with Lynch Syndrome have colonoscopy check-up every 2 years after reaching a certain age; however, they face many challenges which make it difficult to have the recommended check-up. Among a subset of people with Lynch Syndrome in England, this study will investigate the: - percentage who are having colonoscopy check-up as recommended by UK guidelines - factors influencing whether a person is more/less likely to have the recommended colonoscopy check-up - views, experiences, and challenges of living with Lynch Syndrome and colonoscopy check-up This study will collect information from people in the 'Lynch Syndrome registry pilot' using a questionnaire. The Cancer Screening and Prevention Research Group (CSPRG) at Imperial College London are conducting the Lynch Syndrome registry pilot, which is recruiting people with Lynch Syndrome who are aged >18 years and in the Cancer Prevention Programme 3 (CaPP3) trial, from Nov 2022-Nov 2023. This study will include people in the Lynch Syndrome registry pilot who provided consent on the registry pilot consent form to be contacted about future research and are aged ≥25 years. People who have had previous surgery to remove their rectum will be excluded. The investigators will use the 'Views, experiences, and challenges of colonoscopy check-up' questionnaire, together with a few pieces of additional information previously collected as part of the Lynch Syndrome registry pilot. Participation involves completing the questionnaire only. The study will take approximately one year from administering the questionnaire to sharing results with participants.

Criteria for eligibility:

Study pop:
This study will include people who are in the Lynch Syndrome registry pilot and meet the eligibility criteria for the present study. The Lynch Syndrome registry pilot is recruiting people with Lynch Syndrome who are aged >18 years and in the CaPP3 trial.

Sampling method: Non-Probability Sample
Criteria:
Inclusion Criteria: - People in the Lynch Syndrome registry pilot who have provided consent to be contacted about future research and are aged ≥25 years Exclusion Criteria: - People who have had surgery involving removal of their rectum

Gender: All

Minimum age: 25 Years

Maximum age: N/A

Healthy volunteers: No

Locations:

Facility:
Name: Cancer Screening and Prevention Research Group (CSPRG), Department of Surgery and Cancer, Queen Elizabeth The Queen Mother (QEQM) Building, St Mary's Hospital, Imperial College London

Address:
City: London
Zip: W2 1NY
Country: United Kingdom

Start date: January 17, 2024

Completion date: December 2024

Lead sponsor:
Agency: Imperial College London
Agency class: Other

Source: Imperial College London

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT06126120