Trial Title:
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
NCT ID:
NCT06136624
Condition:
Prostate Cancer Metastatic
Conditions: Official terms:
Prostatic Neoplasms
Dexamethasone
Prednisone
Hydrocortisone
Fludrocortisone
Abiraterone Acetate
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Opevesostat
Description:
Administered orally
Arm group label:
Opevesostat
Other name:
MK-5684
Intervention type:
Drug
Intervention name:
Abiraterone acetate
Description:
Administered orally
Arm group label:
Abiraterone Acetate or Enzalutamide
Other name:
ZYTIGA
Other name:
YONSA
Intervention type:
Drug
Intervention name:
Enzalutamide
Description:
Administered orally
Arm group label:
Abiraterone Acetate or Enzalutamide
Other name:
XTANDI
Intervention type:
Drug
Intervention name:
Hydrocortisone
Description:
Administered orally or IM as a rescue medication
Arm group label:
Opevesostat
Intervention type:
Drug
Intervention name:
Fludrocortisone acetate
Description:
Administered orally
Arm group label:
Opevesostat
Intervention type:
Drug
Intervention name:
Prednisone
Description:
Administered orally
Arm group label:
Abiraterone Acetate or Enzalutamide
Intervention type:
Drug
Intervention name:
Dexamethasone
Description:
Administered orally as rescue medication
Arm group label:
Opevesostat
Summary:
This is a phase 3, randomized, open-label study of opevesostat compared to alternative
abiraterone acetate or enzalutamide in participants with metastatic castration-resistant
prostate cancer (mCRPC) with respect to overall survival (OS) and to radiographic
progression-free survival (rPFS) per Prostate Cancer Working Group (PCWG) Modified
Response Evaluation Criteria In Solid Tumors (RECIST 1.1) as assessed by blinded
independent central review (BICR) in participants with mCRPC previously treated with
next-generation hormonal agent (NHA) and taxane-based chemotherapy. It is hypothesized
that opevesostat is superior with respect to OS and rPFS per PCWG Modified RECIST 1.1 as
assessed by BICR in androgen receptor ligand binding domain (AR LBD) mutation-negative
and -positive participants.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Has histologically- or cytologically-confirmed adenocarcinoma of the prostate
without small cell histology
- Has prostate cancer progression while on androgen deprivation therapy (or post
bilateral orchiectomy) within 6 months before Screening
- Has current evidence of metastatic disease documented by either bone lesions on bone
scan and/or soft tissue disease by computed tomography/magnetic resonance imaging
(CT/MRI)
- Has disease that progressed during or after treatment with 1 novel hormonal agent
(NHA)
- Has received 1 but no more than 2 taxane-based chemotherapy regimens for metastatic
castration-resistant prostate cancer (mCRPC) and has had progressive disease (PD)
during or after treatment
- Has ongoing androgen deprivation with serum testosterone <50 ng/dL (<1.7 nM)
- Has provided tumor tissue from a fresh core or excisional biopsy from soft tissue
not previously irradiated
- Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
assessed within 7 days of randomization
- Has had prior treatment with PARPi or were deemed ineligible to receive treatment by
the investigator or have refused PARPi treatment
- Has received prior 177Lu-PSMA-617 or were deemed ineligible to receive
177Lu-PSMA-617 treatment by the investigator or refused 177Lu-PSMA-617 treatment
- Participants who have not received cabazitaxel can be enrolled if they are
ineligible for cabazitaxel treatment as determined by the investigator or have
refused treatment
- If participant received first generation anti-androgen therapy before screening, the
participant has evidence of disease progression >4 weeks since the last flutamide
treatment and >6 weeks since the last bicalutamide or nilutamide treatment
- Participants receiving bone resorptive therapy (including, but not limited to,
bisphosphonate or denosumab) must have been on stable doses for ≥ 4 weeks before the
date of randomization
- Participants with human immunodeficiency virus (HIV) infection must have well
controlled HIV on antiretroviral therapy (ART)
- Participants who are hepatitis B surface antigen (HBsAg) positive are eligible if
they have received hepatitis B virus (HBV) antiviral therapy for at least 4 weeks
and have undetectable HBV viral load before randomization
- Participants with history of hepatitis C virus (HCV) infection are eligible if HCV
viral load is undetectable at Screening.
- Participants who can produce sperm must agree to the following during the study
treatment period and for at least 7 days after the last dose of opevesostat, for at
least 30 days after the last dose of abiraterone acetate, and for at least 3 months
after the last dose of enzalutamide: EITHER be abstinent OR must agree to use male
condom
Exclusion Criteria:
- Has a gastrointestinal disorder that might affect absorption
- Has a history of pituitary dysfunction
- Has poorly controlled diabetes mellitus
- Has clinically significant abnormal serum potassium or sodium level
- Has a history of active or unstable cardio/cerebro-vascular disease, including
thromboembolic events
- Has a history of seizure within 6 months of providing documented informed consent or
any condition that may predispose to seizures within 12 months before the date of
randomization
- Has a history of clinically significant ventricular arrhythmias
- Has received an anticancer monoclonal antibody (mAb) within 4 weeks before the date
of randomization, or has not recovered from adverse events (AEs) due to mAbs
administered more than 4 weeks before the date of randomization
- Has undergone major surgery, including local prostate intervention (except prostate
biopsy), within 28 days before the date of randomization, and has not recovered from
the toxicities and/or complications
- Participants who have not adequately recovered from major surgery or have ongoing
surgical complications
- Has used herbal or medicinal products that may have hormonal anti-prostate cancer
activity and/or are known to decrease prostate-specific Antigen (PSA) (eg, saw
palmetto, megesterol acetate) within 4 weeks before the date of randomization
- Has received radium-223 or lutetium-177 within 4 weeks before the date of
randomization, or has not recovered to Grade ≤1 or baseline from AEs due to
radium-223 or lutetium-177 administered more than 4 weeks before the date of
randomization
- Has received treatment with 5-αreductase inhibitors (eg, finasteride or
dutasteride), estrogens, or cyproterone within 4 weeks before the date of
randomization
- Has received colony-stimulating factors within 28 days before the date of
randomization
- Has received a whole blood transfusion in the last 120 days before the date of
randomization. Packed red blood cells and platelet transfusions are acceptable if
not given within 28 days of the date of randomization
- Has received prior targeted small molecule therapy or NHA treatment within 4 weeks
before the first dose of study intervention as follows: enzalutamide or apalutamide
within 3 weeks or abiraterone acetate + prednisone or darolutamide within 2 weeks
- Has a "superscan" bone scan
- Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy
or any other form of immunosuppressive therapy within 7 days prior the first dose of
study medication
- Has a known additional malignancy that is progressing or has required active
treatment within the past 3 years
- Has known active central nervous system (CNS) metastases and/or carcinomatous
meningitis
- Has an active autoimmune disease that has required systemic treatment in past 2
years
- Has an active infection requiring systemic therapy
- Has concurrent active HBV or known active HCV infection
- Has a history of long QTc syndrome
- Has any of the following at Screening Visit: hypotension (systolic BP <110 mm Hg) or
uncontrolled hypertension (systolic BP ≥160 mm Hg or diastolic BP ≥90 mm Hg, in 2
out of 3 recordings with optimized antihypertensive therapy)
- Is unable to swallow capsules/tablets
- Is currently being treated with cytochrome 450-inducing antiepileptic drugs for
seizures
- Participants on an unstable dose of thyroid hormone therapy within 6 months before
the start of the study intervention
- Received prior systemic anticancer therapy including investigational agents within 4
weeks before the first dose of study intervention
- Received prior radiotherapy within 2 weeks of start of study intervention, or
radiation-related toxicities, requiring corticosteroids
- Received a live or live-attenuated vaccine within 30 days before the first dose of
study intervention
- Systemic use of the following medications within 2 weeks before the first dose of
study intervention: strong CYP3A4 inducers (eg, avasimibe, carbamazepine,
lumacaftor, phenobarbital, rifampicin, rifapentine, or St John's Wort); P-gp
inhibitors (eg, erythromycin, clarithromycin, rifampicin, ketoconazole,
itraconazole, posaconazole, artesunate-pyronaridine, ritonavir, indinavir,
nelfinavir, atazanavir, glecaprevir-pibrentasvir, simeprevir, ledipasvir-sofosbuvir,
verapamil, diltiazem, dronedarone, propafenone, quinidine, cyclosporine, valspodar,
or milk thistle [Silybum marianum])
- Use of aldosterone antagonist (eg, spironolactone, eplerenone) and phenytoin within
4 weeks before the start of the study intervention
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0040)
Address:
City:
Orange
Zip:
92868
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
502-472-3237
Facility:
Name:
Colorado Clinical Research ( Site 0067)
Address:
City:
Lakewood
Zip:
80228
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
303-885-9828
Facility:
Name:
Bruce W. Carter Veterans Affairs Medical Center ( Site 0082)
Address:
City:
Miami
Zip:
33125
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
786-514-9923
Facility:
Name:
University of Miami Hospital and Clinics, Sylvester Cancer Center ( Site 0051)
Address:
City:
Miami
Zip:
33136
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
305-243-1543
Facility:
Name:
University of Chicago Medical Center ( Site 0045)
Address:
City:
Chicago
Zip:
60637
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
773-702-7609
Facility:
Name:
University of Iowa ( Site 0047)
Address:
City:
Iowa City
Zip:
52242
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
319-230-8823
Facility:
Name:
University of Kentucky Chandler Medical Center ( Site 0048)
Address:
City:
Lexington
Zip:
40536
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
859-323-2964
Facility:
Name:
Baltimore Veterans Affairs Medical Center ( Site 0069)
Address:
City:
Baltimore
Zip:
21201
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
410-707-4011
Facility:
Name:
Greenebaum Comprehensive Cancer Center ( Site 0049)
Address:
City:
Baltimore
Zip:
21201
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
410-707-4011
Facility:
Name:
Henry Ford Hospital ( Site 0015)
Address:
City:
Detroit
Zip:
48202
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
313-916-1784
Facility:
Name:
M Health Fairview Clinics and Surgery Center ( Site 0019)
Address:
City:
Minneapolis
Zip:
55455
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
612-626-1422
Facility:
Name:
Metro-Minnesota Community Clinical Oncology ( Site 0014)
Address:
City:
Saint Louis Park
Zip:
55416
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
952-993-3252
Facility:
Name:
Washington University School of Medicine-Internal Medicine/Oncology ( Site 0062)
Address:
City:
Saint Louis
Zip:
63110
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
314-286-2341
Facility:
Name:
Comprehensive Cancer Centers of Nevada ( Site 0010)
Address:
City:
Las Vegas
Zip:
89148
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
702-952-1251
Facility:
Name:
Rutgers Cancer Institute of New Jersey ( Site 0033)
Address:
City:
New Brunswick
Zip:
08903
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
732-235-8663
Facility:
Name:
University Hospitals Cleveland Medical Center ( Site 0043)
Address:
City:
Cleveland
Zip:
44106
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
216-844-3951
Facility:
Name:
VA Portland Health Care System ( Site 0058)
Address:
City:
Portland
Zip:
97239
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
503-220-8262
Facility:
Name:
AHN Allegheny General Hospital ( Site 0001)
Address:
City:
Pittsburgh
Zip:
15212
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
412-359-8373
Facility:
Name:
Ralph H. Johnson VA Health Care System (RHJVAHCS)-Urology ( Site 0083)
Address:
City:
Charleston
Zip:
29401
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
843-792-1414
Facility:
Name:
University of Virginia Health System ( Site 0054)
Address:
City:
Charlottesville
Zip:
22908
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
434-327-3029
Facility:
Name:
VCU Health Adult Outpatient Pavillion ( Site 0061)
Address:
City:
Richmond
Zip:
23219
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
804-828-5941
Facility:
Name:
Blue Ridge Cancer Care ( Site 0004)
Address:
City:
Roanoke
Zip:
24014
Country:
United States
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
540-982-0237
Facility:
Name:
Hospital Británico de Buenos Aires-Oncology ( Site 0202)
Address:
City:
Ciudad autónoma de Buenos Aires
Zip:
C1280AEB
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
54911563819972
Facility:
Name:
Instituto de Investigaciones Clínicas Mar del Plata ( Site 0201)
Address:
City:
Mar del Plata
Zip:
B7600FZO
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+5492235937663
Facility:
Name:
Asociación de Beneficencia Hospital Sirio Libanés ( Site 0205)
Address:
City:
Buenos Aires
Zip:
C1419AHN
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5491157654803
Facility:
Name:
Instituto Alexander Fleming-Alexander Fleming ( Site 0206)
Address:
City:
Ciudad Autónoma de Buenos Aires
Zip:
1426
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5491149455892
Facility:
Name:
Sanatorio Parque ( Site 0208)
Address:
City:
Rosario
Zip:
S2000DSV
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5493416149812
Facility:
Name:
Hospital Aleman-Oncology ( Site 0207)
Address:
City:
Buenos Aires
Zip:
C1118AAT
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5491155276956
Facility:
Name:
Fundacion Centro Oncologico de Integración Regional-Medical Oncology ( Site 0204)
Address:
City:
Mendoza
Zip:
M5500AYB
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
9542614666010
Facility:
Name:
Dubbo Hospital ( Site 0235)
Address:
City:
Dubbo
Zip:
2830
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0268096200
Facility:
Name:
Macquarie University-MQ Health Clinical Trials Unit ( Site 0234)
Address:
City:
Macquarie University
Zip:
2109
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0402856430
Facility:
Name:
Westmead Hospital-Department of Medical Oncology ( Site 0232)
Address:
City:
Westmead
Zip:
2145
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
02 8890 5555
Facility:
Name:
Princess Alexandra Hospital-Cancer Care Serices ( Site 0237)
Address:
City:
Brisbane
Zip:
4102
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
61 7 3176 5564
Facility:
Name:
Peter MacCallum Cancer Centre-Parkville Cancer Clinical Trials Unit (PCCTU) ( Site 0230)
Address:
City:
Melbourne
Zip:
3000
Country:
Australia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
03 8559 5000
Facility:
Name:
Ordensklinikum Linz GmbH Elisabethinen-Urologie ( Site 0276)
Address:
City:
Linz
Zip:
4020
Country:
Austria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4373276774724
Facility:
Name:
Klinikum Wels-Grieskirchen GmbH ( Site 0279)
Address:
City:
Wels
Zip:
4600
Country:
Austria
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
072424152328
Facility:
Name:
Obras Sociais Irma Dulce ( Site 0302)
Address:
City:
Salvador
Zip:
40415-006
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5571991219271
Facility:
Name:
Hospital Santa Rita de Cassia-Centro de Pesquisa Clínica ( Site 0320)
Address:
City:
Vitoria
Zip:
29041-295
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
27998469004
Facility:
Name:
Hospital Felicio Rocho ( Site 0317)
Address:
City:
Belo Horizonte
Zip:
30110-934
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+5531986622882
Facility:
Name:
Hospital Mario Penna ( Site 0309)
Address:
City:
Belo Horizonte
Zip:
30380-472
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
31988032851
Facility:
Name:
Hospital Universitário Evangélico Mackenzie-Centro de Oncologia Mackenzie ( Site 0314)
Address:
City:
Curitiba
Zip:
80440-220
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5541991681411
Facility:
Name:
Clínica de Neoplasias Litoral ( Site 0305)
Address:
City:
Itajai
Zip:
88301-220
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+5547984046243
Facility:
Name:
Hospital Universitário São Francisco de Assis - Bragança Paulista ( Site 0308)
Address:
City:
Bragança Paulista
Zip:
12916-542
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
11 2490-1366
Facility:
Name:
A. C. Camargo Cancer Center ( Site 0310)
Address:
City:
São Paulo
Zip:
01509-010
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
551121895021
Facility:
Name:
Cross Cancer Institute ( Site 0332)
Address:
City:
Edmonton
Zip:
T6G 1Z2
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
7804328762
Facility:
Name:
The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre ( Site 0336)
Address:
City:
Ottawa
Zip:
K1H 8L6
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
514-757-8176
Facility:
Name:
Sunnybrook Research Institute ( Site 0331)
Address:
City:
Toronto
Zip:
M4N 3M5
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
647-533-1023
Facility:
Name:
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre ( Site 0328)
Address:
City:
Greenfield Park
Zip:
J4V 2H1
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
45046650003226
Facility:
Name:
Centre Hospitalier de l'Université de Montréal ( Site 0326)
Address:
City:
Montréal
Zip:
H2X 3E4
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
5148178779
Facility:
Name:
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0
Address:
City:
Quebec City
Zip:
G1J 1Z4
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
418 525-4444
Facility:
Name:
Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer
Address:
City:
Sherbrooke
Zip:
J1H 5H4
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
819-346-1110x12811
Facility:
Name:
IC La Serena Research ( Site 0356)
Address:
City:
La Serena.
Zip:
1720430
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
56993718661
Facility:
Name:
Clinical Research Chile SpA ( Site 0358)
Address:
City:
Valdivia
Zip:
5110683
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+56940601237
Facility:
Name:
Clinica Universidad Catolica del Maule-Oncology ( Site 0355)
Address:
City:
Talca
Zip:
3465584
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
56992992913
Facility:
Name:
FALP ( Site 0353)
Address:
City:
Santiago
Zip:
7500921
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+56956075934
Facility:
Name:
Pontificia Universidad Catolica de Chile-Hemato-Oncology ( Site 0354)
Address:
City:
Santiago
Zip:
8330032
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
56223547919
Facility:
Name:
Bradfordhill-Clinical Area ( Site 0351)
Address:
City:
Santiago
Zip:
8420383
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+56954240753
Facility:
Name:
Bradford Hill Norte ( Site 0357)
Address:
City:
Antofagasta
Zip:
1240000
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
56994198125
Facility:
Name:
Second Affiliated hospital of Anhui Medical University-Urology ( Site 0408)
Address:
City:
Hefei
Zip:
230000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8613705690883
Facility:
Name:
Peking University First Hospital-Urology ( Site 0390)
Address:
City:
Beijing
Zip:
100034
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 (010) 64008229
Facility:
Name:
Beijing Friendship Hospital Affiliate of Capital University ( Site 0396)
Address:
City:
Beijing
Zip:
100050
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8618601020160
Facility:
Name:
Beijing Cancer hospital-Urinary Surgery ( Site 0395)
Address:
City:
Beijing
Zip:
100142
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8613910571565
Facility:
Name:
Chongqing University Cancer Hospital ( Site 0416)
Address:
City:
Chongqing
Zip:
400030
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13452866288
Facility:
Name:
Southwest Hospital of Third Military Medical University ( Site 0420)
Address:
City:
Chongqing
Zip:
400038
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+8602368765862
Facility:
Name:
The First Affiliated Hospital Of Fujian Medical University-Urology ( Site 0414)
Address:
City:
Fuzhou
Zip:
350005
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13235907575
Facility:
Name:
The First Affiliated hospital of Xiamen University-Urology ( Site 0415)
Address:
City:
Xiamen
Zip:
361003
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8613806089889
Facility:
Name:
The First Affiliated Hospital of Guangzhou Medical University-Urology ( Site 0412)
Address:
City:
Guangzhou
Zip:
510120
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13719007083
Facility:
Name:
Sun Yat-sen University Cancer Center-Internal medicine ( Site 0413)
Address:
City:
Guangzhou
Zip:
511400
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13609058827
Facility:
Name:
Tongji Hospital Tongji Medical,Science & Technology ( Site 0407)
Address:
City:
Wuhan
Zip:
430000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13971656164
Facility:
Name:
Hubei Cancer Hospital-Urinary surgery ( Site 0406)
Address:
City:
Wuhan
Zip:
430079
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8613907110640
Facility:
Name:
Hunan Cancer Hospital ( Site 0405)
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
89762270
Facility:
Name:
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S
Address:
City:
NanJing
Zip:
210008
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8613605171690
Facility:
Name:
Jiangxi Provincial Cancer Hospital ( Site 0386)
Address:
City:
Nanchang
Zip:
330029
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13870628187
Facility:
Name:
The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 0393)
Address:
City:
Xi'an
Zip:
710061
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
8615991752560
Facility:
Name:
Fudan University Shanghai Cancer Center-Urology department ( Site 0376)
Address:
City:
Shanghai
Zip:
200000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 21 64175590-1805
Facility:
Name:
Huadong Hospital Affiliated to Fudan University-Urology ( Site 0388)
Address:
City:
Shanghai
Zip:
200041
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13301807126
Facility:
Name:
West China Hospital, Sichuan University-Urology Surgery ( Site 0417)
Address:
City:
Cheng Du
Zip:
610041
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
86 13881749152
Facility:
Name:
Nanchong Central Hospital-urology ( Site 0422)
Address:
City:
Nanchong
Zip:
637000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
08172606822
Facility:
Name:
Tianjin Medical University Cancer Institute & Hospital ( Site 0392)
Address:
City:
Tianjin
Zip:
300060
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13803000688
Facility:
Name:
The Second Hospital of Tianjin Medical University ( Site 0391)
Address:
City:
Tianjin
Zip:
300211
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
86 15122286696
Facility:
Name:
Xinjiang Medical University Cancer Hospital - Urumqi-Urology ( Site 0419)
Address:
City:
Urumqi
Zip:
830000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13609982787
Facility:
Name:
Yunnan Province Cancer Hospital ( Site 0418)
Address:
City:
Kunming
Zip:
650118
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86-13759141758
Facility:
Name:
Zhejiang Provincial People's Hospital-Urology ( Site 0378)
Address:
City:
Hangzhou
Zip:
310014
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13858019285
Facility:
Name:
The First Hospital of Jiaxing-urology ( Site 0380)
Address:
City:
Jiaxing
Zip:
314001
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
13957391616
Facility:
Name:
Ningbo First Hospital-Urology ( Site 0383)
Address:
City:
Ningbo
Zip:
315010
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
15958800971
Facility:
Name:
The First Affiliated Hospital of Wenzhou Medical University-Urology Surgery ( Site 0379)
Address:
City:
Wenzhou
Zip:
325000
Country:
China
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+86 13857771505
Facility:
Name:
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0502)
Address:
City:
Valledupar
Zip:
200001
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
57 3128385292
Facility:
Name:
Oncomedica S.A.S ( Site 0504)
Address:
City:
Montería
Zip:
230002
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+57 3205669416
Facility:
Name:
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 0501)
Address:
City:
Bogota
Zip:
111321
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
573103469453
Facility:
Name:
Fundación Cardiovascular de Colombia ( Site 0503)
Address:
City:
Piedecuesta
Zip:
681017
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
573215433439
Facility:
Name:
Fundación Valle del Lili ( Site 0505)
Address:
City:
Cali
Zip:
760032
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
57 3162801914
Facility:
Name:
Clínica Imbanaco S.A.S ( Site 0509)
Address:
City:
Cali
Zip:
760042
Country:
Colombia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
3174242290
Facility:
Name:
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0553)
Address:
City:
Brno
Zip:
656 53
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
420543136216
Facility:
Name:
Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 0554)
Address:
City:
Ostrava
Zip:
708 52
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
420597372264
Facility:
Name:
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 0555)
Address:
City:
Olomouc
Zip:
779 00
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
420588444717
Facility:
Name:
Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 0551)
Address:
City:
Praha
Zip:
150 06
Country:
Czechia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
420734236410
Facility:
Name:
Rigshospitalet ( Site 0576)
Address:
City:
Copenhagen
Zip:
2100
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4535458397
Facility:
Name:
Odense Universitetshospital-Department of oncology ( Site 0579)
Address:
City:
Odense
Zip:
5000
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4529335922
Facility:
Name:
Vejle Sygehus ( Site 0578)
Address:
City:
Vejle
Zip:
7100
Country:
Denmark
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4550343847
Facility:
Name:
Tampereen yliopistollinen sairaala ( Site 0604)
Address:
City:
Tampere
Zip:
33520
Country:
Finland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
358331166811
Facility:
Name:
Kuopion Yliopistollinen Sairaala ( Site 0603)
Address:
City:
Kuopio
Zip:
70210
Country:
Finland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
35817173311
Facility:
Name:
Turku University Hospital-Department of Oncology ( Site 0601)
Address:
City:
Turku
Zip:
20520
Country:
Finland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
35823130729
Facility:
Name:
Institut de cancérologie Strasbourg Europe (ICANS) ( Site 0627)
Address:
City:
Strasbourg
Zip:
67033
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33368766767
Facility:
Name:
Centre Hospitalier Universitaire de Nîmes - Institut de Cancérologie du Gard - Hôpital Universitaire
Address:
City:
Nîmes
Zip:
30029
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33466683301
Facility:
Name:
Gustave Roussy ( Site 0626)
Address:
City:
Villejuif
Zip:
94800
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+33142116264
Facility:
Name:
Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer ( Site 0632)
Address:
City:
Rennes
Zip:
35042
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33299253182
Facility:
Name:
Centre Jean Perrin - Centre Régional de Lutte contre le Cancer d'Auvergne ( Site 0629)
Address:
City:
Clermont-Ferrand
Zip:
63011
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33473278131
Facility:
Name:
Centre Hospitalier de la Côte Basque ( Site 0633)
Address:
City:
Bayonne
Zip:
64109
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+33559443535
Facility:
Name:
Hôpital Européen Georges Pompidou ( Site 0628)
Address:
City:
Paris
Zip:
75015
Country:
France
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
33156093447
Facility:
Name:
klinikum rechts der isar der technischen universität münchen-Urologische Klinik und Poliklinik ( Sit
Address:
City:
Munich
Zip:
81675
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
498941402522
Facility:
Name:
HELIOS Kliniken Schwerin ( Site 0694)
Address:
City:
Schwerin
Zip:
19055
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+493855202120
Facility:
Name:
Universitätsklinikum Bonn-Klinik und Poliklinik für Urologie und Kinderurologie ( Site 0680)
Address:
City:
Bonn
Zip:
53127
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+4922828714249
Facility:
Name:
Universitätsklinikum Münster - Albert Schweitzer Campus-Klinik für Urologie ( Site 0678)
Address:
City:
Münster
Zip:
48149
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0049251-8344658
Facility:
Name:
Universitätsklinikum Schleswig-Holstein-Klinik für Urologie ( Site 0691)
Address:
City:
Lubeck
Zip:
23538
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
494515002290
Facility:
Name:
Universitätsklinikum Jena-Klinik und Poliklinik für Urologie ( Site 0682)
Address:
City:
Jena
Zip:
07747
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+49 3641 9 32 9947
Facility:
Name:
Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0679)
Address:
City:
Berlin
Zip:
10117
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0049 30 450615297
Facility:
Name:
Universitaetsklinikum Hamburg-Eppendorf-Onkologisches Zentrum ( Site 0705)
Address:
City:
Hamburg
Zip:
20246
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+49 15222815585
Facility:
Name:
Queen Mary Hospital ( Site 0727)
Address:
City:
Hksar
Country:
Hong Kong
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
85222556220
Facility:
Name:
Prince of Wales Hospital ( Site 0730)
Address:
City:
Shatin
Country:
Hong Kong
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
85226321042
Facility:
Name:
Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 0752)
Address:
City:
Kecskemét
Zip:
6000
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+3676516719
Facility:
Name:
Nograd Varmegyei Szent Lazar Korhaz-Onkologia es Sugarterapias Osztaly ( Site 0761)
Address:
City:
Salgótarján
Zip:
3100
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+3632522000
Facility:
Name:
Országos Onkológiai Intézet-Urogenitális Tumorok és Klinikai Farmakológiai Osztály ( Site 0756)
Address:
City:
Budapest
Zip:
1122
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
36122486001171
Facility:
Name:
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 0758)
Address:
City:
Debrecen
Zip:
4032
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+3652411717
Facility:
Name:
St. Vincent's University Hospital ( Site 0802)
Address:
City:
Dublin
Zip:
D04 N2E0
Country:
Ireland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
35314144208
Facility:
Name:
Tallaght University Hospital ( Site 0801)
Address:
City:
Dublin
Zip:
D24 NR0A
Country:
Ireland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
35314144208
Facility:
Name:
Emek Medical Center ( Site 0830)
Address:
City:
Afula
Zip:
1834111
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+97246495540
Facility:
Name:
Rambam Health Care Campus-Oncology Division ( Site 0826)
Address:
City:
Haifa
Zip:
3109601
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
97247776750
Facility:
Name:
Hadassah Medical Center ( Site 0833)
Address:
City:
Jerusalem
Zip:
9112001
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
972505172315
Facility:
Name:
Meir Medical Center. ( Site 0832)
Address:
City:
Kfar Saba
Zip:
4428164
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
972-9-7471606
Facility:
Name:
Rabin Medical Center ( Site 0828)
Address:
City:
Petah Tikva
Zip:
4941492
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+972-39378074
Facility:
Name:
Sheba Medical Center ( Site 0827)
Address:
City:
Ramat Gan
Zip:
5265601
Country:
Israel
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0525505090
Facility:
Name:
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 08
Address:
City:
Meldola
Zip:
47014
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+390543739100
Facility:
Name:
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 0877)
Address:
City:
Milan
Zip:
20133
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
00390223903033
Facility:
Name:
Ospedale San Raffaele-Oncologia Medica ( Site 0876)
Address:
City:
Milano
Zip:
20132
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+390226435668
Facility:
Name:
Toho University Sakura Medical Center ( Site 0906)
Address:
City:
Sakura
Zip:
285-8741
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81434628811
Facility:
Name:
Ehime University Hospital ( Site 0918)
Address:
City:
Toon
Zip:
791-0295
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-89-964-5111
Facility:
Name:
Hospital of the University of Occupational and Environmental Health, Japan ( Site 0921)
Address:
City:
Kitakyushu
Zip:
807-8556
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81936031611
Facility:
Name:
Asahikawa Medical University Hospital ( Site 0901)
Address:
City:
Asahikawa
Zip:
078-8510
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-166-65-2111
Facility:
Name:
Sapporo Medical University Hospital ( Site 0902)
Address:
City:
Sapporo
Zip:
060-8543
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-11-611-2111
Facility:
Name:
Hokkaido University Hospital ( Site 0931)
Address:
City:
Sapporo
Zip:
060-8648
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81117161161
Facility:
Name:
Kobe University Hospital ( Site 0914)
Address:
City:
Kobe
Zip:
650-0017
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81783825111
Facility:
Name:
Kanazawa Medical University Hospital ( Site 0909)
Address:
City:
Uchinada
Zip:
920-0265
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-76-286-3511
Facility:
Name:
Kagawa University Hospital ( Site 0917)
Address:
City:
Kita
Zip:
761-0701
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81878985111
Facility:
Name:
Yokohama City University Medical Center ( Site 0908)
Address:
City:
Yokohama
Zip:
232-0024
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81452615656
Facility:
Name:
National Hospital Organization Nagasaki Medical Center ( Site 0923)
Address:
City:
Ōmura
Zip:
856-8562
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-957-52-3121
Facility:
Name:
Nara Medical University Hospital ( Site 0915)
Address:
City:
Kashihara
Zip:
634-8522
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81744223051
Facility:
Name:
Nanbu Tokushukai Hospital ( Site 0930)
Address:
City:
Shimajiri
Zip:
901-0417
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-98-998-3221
Facility:
Name:
Kansai Medical University Hospital ( Site 0912)
Address:
City:
Hirakata
Zip:
573-1191
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-72-804-0101
Facility:
Name:
Bell Land General Hospital ( Site 0913)
Address:
City:
Sakai
Zip:
599-8247
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81722342001
Facility:
Name:
Osaka University Hospital ( Site 0911)
Address:
City:
Suita
Zip:
565-0871
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81668795111
Facility:
Name:
Saga-Ken Medical Centre Koseikan ( Site 0922)
Address:
City:
Saga-shi
Zip:
840-8571
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81952242171
Facility:
Name:
Akita University Hospital ( Site 0904)
Address:
City:
Akita
Zip:
010-8543
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81188341111
Facility:
Name:
Kyushu University Hospital ( Site 0919)
Address:
City:
Fukuoka
Zip:
812-8582
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81926411151
Facility:
Name:
Gifu University Hospital ( Site 0910)
Address:
City:
Gifu
Zip:
501-1112
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-58-230-6000
Facility:
Name:
Hiroshima University Hospital ( Site 0916)
Address:
City:
Hiroshima
Zip:
734-8551
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-82-257-5555
Facility:
Name:
Kagoshima University Hospital ( Site 0929)
Address:
City:
Kagoshima
Zip:
890-8520
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-99-275-5111
Facility:
Name:
National Hospital Organization Kumamoto Medical Center ( Site 0924)
Address:
City:
Kumamoto
Zip:
860-0008
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81963536501
Facility:
Name:
Miyazaki Prefectural Miyazaki Hospital ( Site 0927)
Address:
City:
Miyazaki
Zip:
880-8510
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81985244181
Facility:
Name:
Nagano Municipal Hospital ( Site 0932)
Address:
City:
Nagano
Zip:
381-8551
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-26-295-1199
Facility:
Name:
Oita Medical Center ( Site 0925)
Address:
City:
Oita
Zip:
870-0263
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81-97-593-1111
Facility:
Name:
The Jikei University Hospital ( Site 0907)
Address:
City:
Tokyo
Zip:
105-8461
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+81334331111
Facility:
Name:
Asan Medical Center-Oncology ( Site 1402)
Address:
City:
Songpagu
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
82230106095
Facility:
Name:
Seoul National University Hospital-Oncology ( Site 1401)
Address:
City:
Seoul
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
01097705707
Facility:
Name:
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 1404)
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
82222288138
Facility:
Name:
Samsung Medical Center ( Site 1405)
Address:
City:
Seoul
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
82234101767
Facility:
Name:
Hospital Sultan Ismail ( Site 1081)
Address:
City:
Johor Bahru
Zip:
81100
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+60127720765
Facility:
Name:
University Malaya Medical Centre ( Site 1077)
Address:
City:
Lembah Pantai
Zip:
59100
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
60379492120
Facility:
Name:
Sarawak General Hospital-Radiotherapy Unit ( Site 1076)
Address:
City:
Kuching
Zip:
93586
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0167783810
Facility:
Name:
National Cancer Institute ( Site 1079)
Address:
City:
Putrajaya
Zip:
62250
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0123375347
Facility:
Name:
Hospital Kuala Lumpur-Radiotherapy and Oncology ( Site 1078)
Address:
City:
Kuala Lumpur
Zip:
50586
Country:
Malaysia
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
0136288487
Facility:
Name:
Medische Centrum Leeuwarden ( Site 1172)
Address:
City:
Leeuwarden
Zip:
8934 AD
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31582866666
Facility:
Name:
Radboudumc-Medical Oncology ( Site 1152)
Address:
City:
Nijmegen
Zip:
6525 GA
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
31243610353
Facility:
Name:
Zuyderland Medical Centre-Trialbureau Interne Geneeskunde ( Site 1163)
Address:
City:
Sittard-Geleen
Zip:
6162 BG
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31884597777
Facility:
Name:
VieCuri Medisch Centrum ( Site 1173)
Address:
City:
Venlo
Zip:
5912 BL
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31773205555
Facility:
Name:
ETZ Elisabeth-Internal Medicine ( Site 1160)
Address:
City:
Tilburg
Zip:
5022 GC
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31132210000
Facility:
Name:
Nederlands Kanker Instituut - Antoni van Leeuwenhoek - NKI-AVL ( Site 1153)
Address:
City:
Amsterdam
Zip:
1066 CX
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31205122569
Facility:
Name:
Spaarne Gasthuis - Hoofddorp-Oncology ( Site 1170)
Address:
City:
Hoofddorp
Zip:
2134 TM
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31232240000
Facility:
Name:
Meander Medisch Centrum ( Site 1157)
Address:
City:
Amersfoort
Zip:
3813TZ
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31338505050
Facility:
Name:
Haga Ziekenhuis locatie Leyweg-Oncology ( Site 1164)
Address:
City:
Den Haag
Zip:
2545 AA
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31702100000
Facility:
Name:
Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 1151)
Address:
City:
Schiedam
Zip:
3118 JH
Country:
Netherlands
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+31104612692
Facility:
Name:
Tauranga Hospital-Bay of Plenty Clinical Trials Unit ( Site 1201)
Address:
City:
Tauranga
Zip:
3112
Country:
New Zealand
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
6475798153
Facility:
Name:
Dunedin Hospital-Southern Blood and Cancers Service ( Site 1203)
Address:
City:
Dunedin
Zip:
9016
Country:
New Zealand
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
03474 0999
Facility:
Name:
Akershus Universitetssykehus-Onkologisk avdeling ( Site 1227)
Address:
City:
Lørenskog
Zip:
1474
Country:
Norway
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
004793299618
Facility:
Name:
Sykehuset Østfold Kalnes ( Site 1228)
Address:
City:
Sarpsborg
Zip:
1714
Country:
Norway
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
4791508600
Facility:
Name:
St. Olavs Hospital-Kreftklinikken ( Site 1231)
Address:
City:
Trondheim
Zip:
7030
Country:
Norway
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
47 72 82 61 66
Facility:
Name:
Instituto Regional de Enfermedades Neoplasicas del Centro (IREN CENTRO) ( Site 1258)
Address:
City:
Concepcion
Zip:
12125
Country:
Peru
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+51958864658
Facility:
Name:
Aliada-Oncologìa ( Site 1257)
Address:
City:
Lima
Zip:
15036
Country:
Peru
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
51965765959
Facility:
Name:
IPOR Instituto Peruano de Oncología & Radioterapia-Centro de Investigación ( Site 1254)
Address:
City:
Lima
Zip:
15036
Country:
Peru
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
956754968
Facility:
Name:
Oncosalud-Clinical Research ( Site 1260)
Address:
City:
Lima
Zip:
15036
Country:
Peru
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
987484716
Facility:
Name:
INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS-Medical Oncology ( Site 1256)
Address:
City:
Lima
Zip:
15038
Country:
Peru
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
993536140
Facility:
Name:
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1302)
Address:
City:
Bydgoszcz
Zip:
85-796
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
48501446778
Facility:
Name:
Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 1304)
Address:
City:
Torun
Zip:
87-100
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+48 604591913
Facility:
Name:
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1310)
Address:
City:
Siedlce
Zip:
08-110
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
48698826497
Facility:
Name:
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch
Address:
City:
Kielce
Zip:
25-734
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+48885997850
Facility:
Name:
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1303)
Address:
City:
Koszalin
Zip:
75-581
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
48502204953
Facility:
Name:
Puerto Rico Medical Research Center LLC ( Site 1354)
Address:
City:
Hato Rey
Zip:
00917
Country:
Puerto Rico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
7872968394
Facility:
Name:
Ad-Vance Medical Research-Research ( Site 1353)
Address:
City:
Ponce
Zip:
00717
Country:
Puerto Rico
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
7876516697
Facility:
Name:
Pan American Center for Oncology Trials - Ciudadela ( Site 1351)
Address:
City:
San Juan
Zip:
00909
Country:
Puerto Rico
Status:
Completed
Facility:
Name:
National Cancer Centre Singapore ( Site 1377)
Address:
City:
Singapore
Zip:
168583
Country:
Singapore
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+65-64368000
Facility:
Name:
Tan Tock Seng Hospital-Medical Oncology ( Site 1378)
Address:
City:
Singapore
Zip:
308433
Country:
Singapore
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+65-62566011
Facility:
Name:
Hospital Jerez de la Frontera ( Site 1427)
Address:
City:
Jerez de la Frontera
Zip:
11407
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
661753582
Facility:
Name:
Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 1431)
Address:
City:
Madrid
Zip:
28034
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34913368263
Facility:
Name:
Hospital Universitario 12 de Octubre-Medical Oncology ( Site 1433)
Address:
City:
Madrid
Zip:
28041
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
349683609003807
Facility:
Name:
Complexo Hospitalario Universitario de Ourense ( Site 1426)
Address:
City:
Ourense
Zip:
32005
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34649196690
Facility:
Name:
Fundación Instituto Valenciano de Oncología-Oncologico ( Site 1430)
Address:
City:
Valencia
Zip:
46009
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34961104605
Facility:
Name:
Hospital Lucus Augusti-Oncology ( Site 1432)
Address:
City:
Lugo
Zip:
27003
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34982296459
Facility:
Name:
HOSPITAL UNIVERSITARIO VIRGEN DEL ROCIO-Medical Oncology ( Site 1428)
Address:
City:
Sevilla
Zip:
41013
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
34955013068
Facility:
Name:
Karolinska Universitetssjukhuset Solna ( Site 1478)
Address:
City:
Stockholm
Zip:
171 64
Country:
Sweden
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
46851770000
Facility:
Name:
Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 1477)
Address:
City:
Uppsala
Zip:
751 85
Country:
Sweden
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+46736869248
Facility:
Name:
Sahlgrenska Universitetssjukhuset ( Site 1479)
Address:
City:
Gothenburg
Zip:
413 45
Country:
Sweden
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+46 31 342 79 83
Facility:
Name:
China Medical University Hospital-Department of Urology (Site # 1503)
Address:
City:
Taichung
Zip:
40447
Country:
Taiwan
Status:
Recruiting
Contact:
Last name:
Chi-Ping Huang
Phone:
886-975-681295
Facility:
Name:
National Cheng Kung University Hospital-Urology (Site # 1502)
Address:
City:
Tainan
Zip:
704
Country:
Taiwan
Status:
Recruiting
Contact:
Last name:
Yuh-Shyan Tsai
Phone:
886623535355251
Facility:
Name:
National Taiwan University Hospital-Urology (Site # 1506)
Address:
City:
Taipei
Zip:
10002
Country:
Taiwan
Status:
Recruiting
Contact:
Last name:
Yeong-Shiau Pu
Phone:
88622312345665238
Facility:
Name:
Taipei Veterans General Hospital (Site # 1505)
Address:
City:
Taipei
Zip:
112
Country:
Taiwan
Status:
Recruiting
Contact:
Last name:
Hsiao-Jen Chung
Phone:
886228757519304
Facility:
Name:
Chang Gung MedicalFoundation-Linkou Branch-Medical Oncology (Site #1504)
Address:
City:
Taoyuan
Zip:
333
Country:
Taiwan
Status:
Recruiting
Contact:
Last name:
Po-Jung Su
Phone:
+886-975366135
Facility:
Name:
Faculty of Medicine - Khon Kaen University ( Site 1526)
Address:
City:
Muang
Zip:
40002
Country:
Thailand
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+66 43 366568-9
Facility:
Name:
Chulalongkorn University ( Site 1530)
Address:
City:
Bangkok
Zip:
10330
Country:
Thailand
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
6622564533
Facility:
Name:
Faculty of Medicine Siriraj Hospital ( Site 1531)
Address:
City:
Bangkok
Zip:
10700
Country:
Thailand
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
6624194488
Facility:
Name:
Songklanagarind hospital ( Site 1527)
Address:
City:
Hatyai
Zip:
90110
Country:
Thailand
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
6674451469
Facility:
Name:
Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 1554)
Address:
City:
Adana
Zip:
01250
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+903223444444
Facility:
Name:
Gulhane Egitim Arastirma Hastanesi ( Site 1558)
Address:
City:
Ankara
Zip:
06010
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
905366401020
Facility:
Name:
Hacettepe Universite Hastaneleri-oncology hospital ( Site 1551)
Address:
City:
Ankara
Zip:
06230
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+905334318506
Facility:
Name:
Memorial Ankara Hastanesi-Medical Oncology ( Site 1557)
Address:
City:
Ankara
Zip:
06520
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
903122536666
Facility:
Name:
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1552)
Address:
City:
Ankara
Zip:
06800
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
905052933234
Facility:
Name:
Istanbul Universitesi Cerrahpasa-Medical Oncology ( Site 1555)
Address:
City:
Istanbul
Zip:
34668
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+90 2124400000
Facility:
Name:
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1553)
Address:
City:
Istanbul
Zip:
34722
Country:
Turkey
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+902166065200
Facility:
Name:
Addenbrooke's Hospital ( Site 1605)
Address:
City:
Cambridge
Zip:
CB2 2QQ
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+441223245151
Facility:
Name:
The Royal Cornwall Hospital ( Site 1610)
Address:
City:
Truro
Zip:
TR1 3LJ
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
07879876639
Facility:
Name:
The Beatson West of Scotland Cancer Centre ( Site 1603)
Address:
City:
Glasgow
Zip:
G12 0YN
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
+447780777067
Facility:
Name:
Charing Cross Hospital-Oncology Research ( Site 1606)
Address:
City:
London
Zip:
W6 8RF
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
442033110277
Facility:
Name:
University College London Hospital ( Site 1612)
Address:
City:
London
Zip:
NW1 2PG
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
442034479287
Facility:
Name:
The Christie NHS Foundation Trust ( Site 1608)
Address:
City:
Manchester
Zip:
m20 4bx
Country:
United Kingdom
Status:
Recruiting
Contact:
Last name:
Study Coordinator
Phone:
441614463000
Start date:
December 31, 2023
Completion date:
August 2, 2028
Lead sponsor:
Agency:
Merck Sharp & Dohme LLC
Agency class:
Industry
Collaborator:
Agency:
Orion Corporation, Orion Pharma
Agency class:
Industry
Source:
Merck Sharp & Dohme LLC
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06136624
https://www.merckclinicaltrials.com/
