Trial Title:
A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)
NCT ID:
NCT06140836
Condition:
Carcinoma, Non-Small-Cell Lung
Conditions: Official terms:
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Crizotinib
Conditions: Keywords:
TKI-naïve
ROS1
NSCLC
ROS1-positive non-small cell lung cancer
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Repotrectinib
Description:
Specified dose on specified days
Arm group label:
Arm A
Other name:
BMS-986472
Intervention type:
Drug
Intervention name:
Crizotinib
Description:
Specified dose on specified days
Arm group label:
Arm B
Other name:
Xalkori
Summary:
The purpose of this study is to evaluate the efficacy and safety of repotrectinib and
crizotinib in participants with locally advanced or metastatic TKI-naïve ROS1-positive
non-small cell lung cancer (NSCLC).
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Participant has histologically or cytologically confirmed diagnosis of locally
advanced or metastatic NSCLC
- Participant has a ROS1 gene rearrangement/fusion as detected by a local test.
- At least 1 measurable lesion according to RECIST v1.1, as assessed by the
investigator.
- Participants must not be exposed previously with TKIs that demonstrated activities
in ROS1-positive NSCLC
- Up to 1 prior line of systemic treatment for NSCLC is permitted
- ECOG Performance Status ≤ 2
Exclusion Criteria:
- Symptomatic brain metastases or symptomatic leptomeningeal involvement.
- History of previous cancer requiring therapy within the previous 2 years, except for
NSCLC under study, squamous cell or basal-cell carcinoma of the skin, or any in situ
carcinoma that has been completely resected.
- Known tumor targetable co-mutations or rearrangements
- Clinically significant cardiovascular disease (either active or within 6 months
prior to enrollment)
Note: Other protocol-defined inclusion/exclusion criteria apply
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Local Institution - 0136
Address:
City:
Augusta
Zip:
30912
Country:
United States
Status:
Withdrawn
Facility:
Name:
Local Institution - 0221
Address:
City:
Des Moines
Zip:
50309
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Site 0221
Facility:
Name:
Massachusetts General Hospital
Address:
City:
Boston
Zip:
02114
Country:
United States
Status:
Recruiting
Contact:
Last name:
Jessica Lin, Site 0075
Phone:
617-724-4000
Facility:
Name:
Beth Israel Deaconess Medical Center
Address:
City:
Boston
Zip:
02215
Country:
United States
Status:
Recruiting
Contact:
Last name:
Daniel Costa, Site 0201
Phone:
617-667-9236
Facility:
Name:
Local Institution - 0217
Address:
City:
Brooklyn
Zip:
11220
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Site 0217
Facility:
Name:
Perlmutter Cancer Center at NYU Langone Hospital - Long Island
Address:
City:
Mineola
Zip:
11501
Country:
United States
Status:
Recruiting
Contact:
Last name:
Vamsidhar Velcheti, Site 0210
Phone:
216-903-4153
Facility:
Name:
Laura and Isaac Perlmutter Cancer Center
Address:
City:
New York
Zip:
10016
Country:
United States
Status:
Recruiting
Contact:
Last name:
Vamsidhar Velcheti, Site 0134
Phone:
216-903-4153
Facility:
Name:
SUNY Upstate Medical University
Address:
City:
Syracuse
Zip:
13210
Country:
United States
Status:
Recruiting
Contact:
Last name:
ALINA BASNET, Site 0127
Phone:
315-464-8200
Facility:
Name:
Local Institution - 0214
Address:
City:
Tacoma
Zip:
98405
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Site 0214
Facility:
Name:
Local Institution - 0061
Address:
City:
Milwaukee
Zip:
53226
Country:
United States
Status:
Withdrawn
Facility:
Name:
Hospital Británico de Buenos Aires
Address:
City:
Ciudad autónoma de Buenos Aires
Zip:
1280
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Karina Vera, Site 0092
Phone:
1121571056
Facility:
Name:
Instituto Alexander Fleming
Address:
City:
Ciudad Autónoma de Buenos Aires
Zip:
C1426ANZ
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Carmen Pupareli, Site 0090
Phone:
+541138850425
Facility:
Name:
Hospital Italiano de Buenos Aires
Address:
City:
ABB
Zip:
C1199ABB
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Lorena Lupinacci, Site 0091
Phone:
5411495902008159
Facility:
Name:
Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC)
Address:
City:
Buenos Aires
Zip:
1431
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Vanina Wainsztein, Site 0106
Phone:
5491149809013
Facility:
Name:
Instituto de Oncología Angel H. Roffo
Address:
City:
Buenos Aires
Zip:
C1417DTB
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Monica Castro, Site 0207
Phone:
+5491141689984
Facility:
Name:
Instituto Oncológico de Córdoba
Address:
City:
Córdoba
Zip:
5000
Country:
Argentina
Status:
Recruiting
Contact:
Last name:
Martin Richardet, Site 0093
Phone:
5493516165267
Facility:
Name:
Klinik Floridsdorf
Address:
City:
Wien
Zip:
1210
Country:
Austria
Status:
Recruiting
Contact:
Last name:
Maximilian Hochmair, Site 0041
Phone:
431277003855
Facility:
Name:
Hospital Luxemburgo
Address:
City:
Belo Horizonte
Zip:
30380-490
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Ellias Lima, Site 0073
Phone:
31988032851
Facility:
Name:
Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa
Address:
City:
Porto Alegre
Zip:
90110-270
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Alan Azambuja, Site 0033
Phone:
555133789927
Facility:
Name:
Hospital São Lucas da PUCRS
Address:
City:
Porto Alegre
Zip:
90610-000
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Ana Caroline Gelatti, Site 0034
Phone:
(51)3320-3039
Facility:
Name:
Fundação Pio XII - Hospital de Câncer de Barretos
Address:
City:
Barretos
Zip:
14784400
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Flavio Augusto Ferreria Da Silva, Site 0029
Phone:
551733216637
Facility:
Name:
Hospital Sírio Libanês
Address:
City:
Sao Paulo
Zip:
01308-060
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Guilherme Harada, Site 0209
Phone:
+5511999300892
Facility:
Name:
Hospital Paulistano
Address:
City:
Sao Paulo
Zip:
01321-001
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Mariana Monteiro, Site 0147
Phone:
+5511944716385
Facility:
Name:
Fundação Faculdade Regional de Medicina de São José do Rio Preto
Address:
City:
São José do Rio Preto
Zip:
15090000
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
BRUNO CEZAR UCHÔA JÚNIOR, Site 0037
Phone:
11997722237
Facility:
Name:
Hospital São Lucas de Copacabana
Address:
City:
Rio de Janeiro
Zip:
22061-080
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Luiz Henrique Araujo, Site 0098
Phone:
552132076585
Facility:
Name:
Grupo Oncoclinicas Botafogo
Address:
City:
Rio de Janeiro
Zip:
22250-905
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Pedro Rafael Martins De Marchi, Site 0108
Phone:
551733216638
Facility:
Name:
Instituto D'Or de Pesquisa e Ensino (IDOR)
Address:
City:
São Paulo
Zip:
01401-002
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Milena Perez Mak, Site 0032
Phone:
551138932632
Facility:
Name:
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein
Address:
City:
São Paulo
Zip:
05652-900
Country:
Brazil
Status:
Recruiting
Contact:
Last name:
Fernando Moura Silva, Site 0114
Phone:
551121511127
Facility:
Name:
Princess Margaret Cancer Centre
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Geoffrey Liu, Site 0002
Phone:
416-8241217
Facility:
Name:
Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec
Address:
City:
Trois-Rivières
Zip:
G8Z 3R9
Country:
Canada
Status:
Recruiting
Contact:
Last name:
Jean Sebastien Aucoin, Site 0123
Phone:
8196973333
Facility:
Name:
FALP
Address:
City:
Santiago
Zip:
7500921
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Christian Caglevic, Site 0094
Phone:
56224457254
Facility:
Name:
Oncocentro Apys
Address:
City:
Viña del Mar
Zip:
2520598
Country:
Chile
Status:
Recruiting
Contact:
Last name:
Alejandro Acevedo, Site 0096
Phone:
+56992369820
Facility:
Name:
Beijing Cancer hospital
Address:
City:
Beijing
Zip:
100142
Country:
China
Status:
Recruiting
Contact:
Last name:
Jian Fang, Site 0168
Phone:
13701224460
Facility:
Name:
Army Medical Center of PLA
Address:
City:
Chongqing
Zip:
400042
Country:
China
Status:
Recruiting
Contact:
Last name:
Yong He, Site 0185
Phone:
13908338998
Facility:
Name:
Local Institution - 0192
Address:
City:
Fuzhou
Zip:
350000
Country:
China
Status:
Withdrawn
Facility:
Name:
The First Affiliated hospital of Xiamen University
Address:
City:
Xiamen
Zip:
361003
Country:
China
Status:
Recruiting
Contact:
Last name:
Feng Ye, Site 0169
Phone:
13860458889
Facility:
Name:
The First Affiliated Hospital of Guangzhou Medical University
Address:
City:
Guangzhou
Zip:
510120
Country:
China
Status:
Recruiting
Contact:
Last name:
Chengzhi Zhou, Site 0180
Phone:
13560351176
Facility:
Name:
The First Affiliated Hospital of Guangxi Medical University
Address:
City:
Nanning
Zip:
530000
Country:
China
Status:
Recruiting
Contact:
Last name:
Qitao Yu, Site 0194
Phone:
13878106696
Facility:
Name:
Affiliated Cancer Hospital of Harbin Medical University
Address:
City:
Harbin
Zip:
150000
Country:
China
Status:
Recruiting
Contact:
Last name:
Yan Yu, Site 0171
Phone:
13904505825
Facility:
Name:
Henan Cancer Hospital
Address:
City:
Zhengzhou
Zip:
450003
Country:
China
Status:
Recruiting
Contact:
Last name:
Xiufeng Hu, Site 0166
Phone:
18339920984
Facility:
Name:
Hubei Cancer Hospital
Address:
City:
Wuhan Shi
Zip:
430079
Country:
China
Status:
Recruiting
Contact:
Last name:
Bin Yang, Site 0181
Phone:
8613407192282
Facility:
Name:
Local Institution - 0203
Address:
City:
Wuhan
Zip:
430022
Country:
China
Status:
Withdrawn
Facility:
Name:
Hunan Province People'S Hospital
Address:
City:
Changsha
Zip:
410000
Country:
China
Status:
Recruiting
Contact:
Last name:
Furen Zeng, Site 0184
Phone:
13874854668
Facility:
Name:
Local Institution - 0165
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Withdrawn
Facility:
Name:
Jiangsu Province Hospital Of Chinese Medicine
Address:
City:
Nanjing
Zip:
210029
Country:
China
Status:
Recruiting
Contact:
Last name:
Qian Wang, Site 0193
Phone:
13813989395
Facility:
Name:
The First Affiliated Hospital of Nanchang University
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Recruiting
Contact:
Last name:
Longhua Sun, Site 0202
Phone:
13698091288
Facility:
Name:
Jilin Cancer Hospital
Address:
City:
Changchun
Zip:
130012
Country:
China
Status:
Recruiting
Contact:
Last name:
Ying Cheng, Site 0178
Phone:
8613943012851
Facility:
Name:
The First Affiliated Hospital of Xi'an Jiaotong University
Address:
City:
Xi'an
Zip:
710061
Country:
China
Status:
Recruiting
Contact:
Last name:
Yu Yao, Site 0183
Phone:
13572101611
Facility:
Name:
Shandong Cancer Hospital
Address:
City:
Jinan
Zip:
250000
Country:
China
Status:
Recruiting
Contact:
Last name:
Wei Huang, Site 0186
Phone:
+13181713436
Facility:
Name:
Local Institution - 0205
Address:
City:
Linyi
Zip:
276027
Country:
China
Status:
Withdrawn
Facility:
Name:
Shanghai Chest Hospital
Address:
City:
Shanghai
Zip:
200030
Country:
China
Status:
Recruiting
Contact:
Last name:
Ziming Li, Site 0164
Phone:
13764590226
Facility:
Name:
Fudan University Shanghai Cancer Center
Address:
City:
Shanghai
Zip:
200032
Country:
China
Status:
Recruiting
Contact:
Last name:
Jialei Wang, Site 0179
Phone:
8613501623469
Facility:
Name:
Local Institution - 0170
Address:
City:
Chengdu
Zip:
610041
Country:
China
Status:
Withdrawn
Facility:
Name:
West China Hospital, Sichuan University
Address:
City:
Chengdu
Zip:
610044
Country:
China
Status:
Recruiting
Contact:
Last name:
Yalun Li, Site 0177
Phone:
18628250623
Facility:
Name:
Local Institution - 0204
Address:
City:
Kunming
Zip:
650106
Country:
China
Status:
Withdrawn
Facility:
Name:
Local Institution - 0206
Address:
City:
Hangzhou
Zip:
310003
Country:
China
Status:
Withdrawn
Facility:
Name:
Zhejiang Cancer Hospital
Address:
City:
Hangzhou
Zip:
310022
Country:
China
Status:
Recruiting
Contact:
Last name:
Xinmin Yu, Site 0175
Phone:
8613705718617
Facility:
Name:
Nouvel Hôpital Civil (NHC)
Address:
City:
Strasbourg
Zip:
67091
Country:
France
Status:
Recruiting
Contact:
Last name:
Celine Mascaux, Site 0059
Phone:
0033369550644
Facility:
Name:
CHU Bordeaux Haut-Leveque
Address:
City:
Pessac
Zip:
33600
Country:
France
Status:
Recruiting
Contact:
Last name:
Remi Veillon, Site 0055
Phone:
33557656338
Facility:
Name:
Centre Georges François Leclerc
Address:
City:
Dijon
Zip:
21079
Country:
France
Status:
Recruiting
Contact:
Last name:
Aurelie Lagrange, Site 0109
Phone:
33380737528
Facility:
Name:
Hopital Charles Nicolle C H U Rouen
Address:
City:
Rouen
Zip:
76031
Country:
France
Status:
Recruiting
Contact:
Last name:
Florian Guisier, Site 0057
Phone:
33232888247
Facility:
Name:
Chu Grenoble Alpes
Address:
City:
La Tronche
Zip:
38700
Country:
France
Status:
Recruiting
Contact:
Last name:
Denis Moro-Sibilot, Site 0058
Phone:
33476765467
Facility:
Name:
Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes
Address:
City:
Saint-Herblain
Zip:
44800
Country:
France
Status:
Recruiting
Contact:
Last name:
Elvire Pons-Tostivint, Site 0189
Phone:
+33676133810
Facility:
Name:
Centre Hospitalier Lyon Sud
Address:
City:
Pierre-Bénite
Zip:
69310
Country:
France
Status:
Recruiting
Contact:
Last name:
Sebastien Couraud, Site 0060
Phone:
33478865924
Facility:
Name:
Hopitaux Universitaires Paris Centre-Hopital Cochin
Address:
City:
Paris
Zip:
75014
Country:
France
Status:
Recruiting
Contact:
Last name:
Marie Wislez, Site 0056
Phone:
33158413091
Facility:
Name:
Klinikum Esslingen
Address:
City:
Esslingen
Zip:
73730
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Martin Faehling, Site 0124
Phone:
+4971131032402
Facility:
Name:
Klinikum Würzburg Mitte
Address:
City:
Wuerzburg
Zip:
97074
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Jens Kern, Site 0105
Phone:
+00499317912814
Facility:
Name:
Pius Hospital Oldenburg
Address:
City:
Oldenburg
Zip:
26121
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Frank Griesinger, Site 0074
Phone:
494412291611
Facility:
Name:
Evangelische Lungenklinik Berlin
Address:
City:
Berlin
Zip:
13125
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Christian Grohe, Site 0078
Phone:
+493094802112
Facility:
Name:
Universitaetsklinikum Carl Gustav Carus Dresden
Address:
City:
Dresden
Zip:
01307
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Martin Wermke, Site 0035
Phone:
+493514587566
Facility:
Name:
Asklepios Klinik Gauting GmbH
Address:
City:
Gauting
Zip:
82131
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Niels Reinmuth, Site 0131
Phone:
004989857914001
Facility:
Name:
Lungenfachklinik Immenhausen
Address:
City:
Immenhausen
Zip:
34376
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Achim Rittmeyer, Site 0071
Phone:
4956735011573
Facility:
Name:
Universitaetsklinikum Koeln
Address:
City:
Köln
Zip:
50937
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Juergen Wolf, Site 0079
Phone:
+49 22147889050
Facility:
Name:
Marienhaus Klinikum Mainz
Address:
City:
Mainz
Zip:
55131
Country:
Germany
Status:
Recruiting
Contact:
Last name:
Michael Kreuter, Site 0199
Phone:
49(0)6131177271
Facility:
Name:
University Hospital of Patras
Address:
City:
Patras
Zip:
26504
Country:
Greece
Status:
Recruiting
Contact:
Last name:
Angelos Koutras, Site 0154
Phone:
306973801212
Facility:
Name:
Thoracic General Hospital of Athens "I Sotiria"
Address:
City:
Athens
Zip:
115 27
Country:
Greece
Status:
Recruiting
Contact:
Last name:
Konstantinos Syrigos, Site 0153
Phone:
302107700220
Facility:
Name:
Attikon General University Hospital
Address:
City:
Chaidari
Zip:
124 62
Country:
Greece
Status:
Recruiting
Contact:
Last name:
Amanda Psyrri, Site 0155
Phone:
2105832549
Facility:
Name:
Theagenio Hospital
Address:
City:
Thessaloniki
Zip:
540 07
Country:
Greece
Status:
Recruiting
Contact:
Last name:
Pavlos Papakotoulas, Site 0156
Phone:
+30-2310-898606
Facility:
Name:
Országos Korányi Pulmonológiai Intézet
Address:
City:
Budapest
Zip:
1121
Country:
Hungary
Status:
Recruiting
Contact:
Last name:
Gyula Ostoros, Site 0135
Phone:
3613913213
Facility:
Name:
Local Institution - 0218
Address:
City:
New Delhi
Zip:
110029
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0218
Facility:
Name:
Local Institution - 0076
Address:
City:
New Delhi
Zip:
110085
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0076
Facility:
Name:
Local Institution - 0102
Address:
City:
Ahmedabad
Zip:
380054
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0102
Facility:
Name:
Local Institution - 0118
Address:
City:
Ahmedabad
Zip:
380060
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0118
Facility:
Name:
Local Institution - 0117
Address:
City:
Gurgaon
Zip:
122002
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0117
Facility:
Name:
Local Institution - 0044
Address:
City:
Gurugram
Zip:
122001
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0044
Facility:
Name:
Local Institution - 0082
Address:
City:
Bengaluru
Zip:
560017
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0082
Facility:
Name:
Local Institution - 0219
Address:
City:
Thiruvananthapuram
Zip:
695011
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0219
Facility:
Name:
Local Institution - 0065
Address:
City:
Mumbai
Zip:
400004
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0065
Facility:
Name:
Local Institution - 0048
Address:
City:
Mumbai
Zip:
400012
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0048
Facility:
Name:
Local Institution - 0045
Address:
City:
Pune
Zip:
411001
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0045
Facility:
Name:
Local Institution - 0049
Address:
City:
Pune
Zip:
411004
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0049
Facility:
Name:
Local Institution - 0220
Address:
City:
Hyderabad
Zip:
500082
Country:
India
Status:
Not yet recruiting
Contact:
Last name:
Site 0220
Facility:
Name:
Fondazione IRCCS Istituto Nazionale dei Tumori
Address:
City:
Milan
Zip:
20133
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Arsela Prelaj, Site 0152
Phone:
+390223903829
Facility:
Name:
Fondazione IRCCS San Gerardo dei Tintori
Address:
City:
Monza
Zip:
20900
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Diego Cortinovis, Site 0149
Phone:
390392333683
Facility:
Name:
A.O.R.N. Ospedale dei Colli - Monaldi V.
Address:
City:
Naples
Zip:
80131
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Danilo Rocco, Site 0150
Phone:
390817064300
Facility:
Name:
Istituto Nazionale Tumori Regina Elena
Address:
City:
Rome
Zip:
00144
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Lorenza Landi, Site 0148
Phone:
+390652665075
Facility:
Name:
Cro-Irccs
Address:
City:
Aviano
Zip:
33081
Country:
Italy
Status:
Recruiting
Contact:
Last name:
Alessandra Bearz, Site 0151
Phone:
390434659294
Facility:
Name:
Nagoya University Hospital
Address:
City:
Nagoya
Zip:
466-8560
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Junji Koyama, Site 0190
Phone:
81527412111
Facility:
Name:
National Cancer Center Hospital East
Address:
City:
Kashiwa
Zip:
277-8577
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Koichi Goto, Site 0132
Phone:
81471331111
Facility:
Name:
National Hospital Organization Shikoku Cancer Center
Address:
City:
Matsuyama
Zip:
791-0280
Country:
Japan
Status:
Recruiting
Contact:
Last name:
TOSHIYUKI KOZUKI, Site 0174
Phone:
+81899991111
Facility:
Name:
Hokkaido University Hospital
Address:
City:
Sapporo
Zip:
060-8648
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Jun Sakakibara, Site 0163
Phone:
+81-11-716-1161
Facility:
Name:
Kanagawa cancer center
Address:
City:
Yokohama
Zip:
2418515
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Seigo Katakura, Site 0173
Phone:
0455202222
Facility:
Name:
Sendai Kosei Hospital
Address:
City:
Sendai
Zip:
9800873
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Shunichi Sugawara, Site 0172
Phone:
81227288000
Facility:
Name:
Tokyo Metropolitan Komagome Hospital
Address:
City:
Bunkyo ku
Zip:
113-8677
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Yukio Hosomi, Site 0198
Phone:
81338232101
Facility:
Name:
Tottori University Hospital
Address:
City:
Yonago
Zip:
683-8504
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Masahiro Kodani, Site 0159
Phone:
0859386292
Facility:
Name:
National Hospital Organization Kyushu Cancer Center
Address:
City:
Fukuoka
Zip:
811-1395
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Masafumi Yamaguchi, Site 0195
Phone:
81925413231
Facility:
Name:
Osaka City General Hospital
Address:
City:
Osaka
Zip:
534-0021
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Haruko Daga, Site 0160
Phone:
81669293269
Facility:
Name:
Osaka International Cancer Institute
Address:
City:
Osaka
Zip:
541-8567
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Kazumi Nishino, Site 0167
Phone:
81669721181
Facility:
Name:
Tokyo Metropolitan Police Hospital
Address:
City:
Tokyo
Zip:
164-8541
Country:
Japan
Status:
Recruiting
Contact:
Last name:
Hiromi Aono, Site 0208
Phone:
03-5343-5611
Facility:
Name:
Chungbuk National University Hospital
Address:
City:
Cheongju-si
Zip:
28644
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Ki Hyeong Lee, Site 0062
Phone:
82432696015
Facility:
Name:
Seoul National University Bundang Hospital
Address:
City:
Seongnam
Zip:
13620
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Yu Jung Kim, Site 0081
Phone:
+82-31-787-7041
Facility:
Name:
Severance Hospital, Yonsei University Health System
Address:
City:
Seoul
Zip:
03722
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Byoung Chul Cho, Site 0064
Phone:
82222288126
Facility:
Name:
Asan Medical Center
Address:
City:
Seoul
Zip:
05505
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Sang-We Kim, Site 0070
Phone:
82230103215
Facility:
Name:
Samsung Medical Center
Address:
City:
Seoul
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Contact:
Last name:
Myung-Ju Ahn, Site 0063
Phone:
82234103438
Facility:
Name:
Local Institution - 0223
Address:
City:
Kuala Lumpur
Zip:
50586
Country:
Malaysia
Status:
Not yet recruiting
Contact:
Last name:
Site 0223
Facility:
Name:
Local Institution - 0237
Address:
City:
Kuala Lumpur
Zip:
50586
Country:
Malaysia
Status:
Not yet recruiting
Contact:
Last name:
Site 0237
Facility:
Name:
Local Institution - 0222
Address:
City:
Lembah Pantai
Zip:
59100
Country:
Malaysia
Status:
Not yet recruiting
Contact:
Last name:
Site 0222
Facility:
Name:
Local Institution - 0226
Address:
City:
Lembah Pantai
Zip:
59100
Country:
Malaysia
Status:
Withdrawn
Facility:
Name:
Local Institution - 0224
Address:
City:
Putrajaya
Zip:
62250
Country:
Malaysia
Status:
Not yet recruiting
Contact:
Last name:
Site 0224
Facility:
Name:
Local Institution - 0216
Address:
City:
Amsterdam
Zip:
1081 HV
Country:
Netherlands
Status:
Not yet recruiting
Contact:
Last name:
Site 0216
Facility:
Name:
Local Institution - 0215
Address:
City:
Groningen
Zip:
9713 GZ
Country:
Netherlands
Status:
Not yet recruiting
Contact:
Last name:
Site 0215
Facility:
Name:
Instytut Genetyki i Immunologii GENIM
Address:
City:
Lublin
Zip:
20-609
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Izabela Chmielewska, Site 0187
Phone:
+504051512
Facility:
Name:
Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie
Address:
City:
Olsztyn
Zip:
10-357
Country:
Poland
Status:
Recruiting
Contact:
Last name:
Jaroslaw Kolb-Sielecki, Site 0196
Phone:
48895322978
Facility:
Name:
SC Memorial Healthcare International SRL
Address:
City:
Bucharest
Zip:
013812
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Ingrid Iordan, Site 0030
Phone:
40721298677
Facility:
Name:
Institutul Oncologic Bucuresti
Address:
City:
Bucharest
Zip:
022328
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Aurelia Alexandru, Site 0066
Phone:
40723289606
Facility:
Name:
Centrul de Oncologie "Sfântul Nectarie"
Address:
City:
Craiova
Zip:
200746
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Michael Schenker, Site 0031
Phone:
40727774974
Facility:
Name:
Institutul Oncologic Cluj
Address:
City:
Cluj
Zip:
400015
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Tudor Ciuleanu, Site 0122
Phone:
40745646368
Facility:
Name:
S.C. Centrul de Oncologie Euroclinic S.R.L.
Address:
City:
Iași
Zip:
700106
Country:
Romania
Status:
Recruiting
Contact:
Last name:
Constantin Volovat, Site 0067
Phone:
40746110096
Facility:
Name:
CHUAC-Hospital Teresa Herrera
Address:
City:
A Coruña
Zip:
15006
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Maria Garcia Campelo, Site 0141
Phone:
34981178353
Facility:
Name:
CHUS - Hospital Clinico Universitario
Address:
City:
Santiago de Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Jorge Garcia Gonzalez, Site 0138
Phone:
34981950511
Facility:
Name:
Hospital Universitari Vall d'Hebron
Address:
City:
Barcelona
Zip:
08035
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Enriqueta Felip Font, Site 0140
Phone:
34932746077
Facility:
Name:
Hospital Universitario 12 de Octubre
Address:
City:
Madrid
Zip:
28041
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Jon Zugazagoitia Fraile, Site 0137
Phone:
913908714
Facility:
Name:
Hospital Universitario Puerta de Hierro Majadahonda
Address:
City:
Majadahonda
Zip:
28222
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Mariano Provencio Pulla, Site 0139
Phone:
34911917759
Facility:
Name:
H.R.U Málaga - Hospital General
Address:
City:
Málaga
Zip:
29011
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Alexandra Cantero Gonzalez, Site 0142
Phone:
(+34)951308130
Facility:
Name:
Hospital Universitario Virgen Del Rocio
Address:
City:
Sevilla
Zip:
41013
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Reyes Bernabe Caro, Site 0144
Phone:
34955015273
Facility:
Name:
Hospital Universitari i Politecnic La Fe
Address:
City:
València
Zip:
46026
Country:
Spain
Status:
Recruiting
Contact:
Last name:
Oscar Juan Vidal, Site 0143
Phone:
34663976139
Facility:
Name:
Kantonspital Baden
Address:
City:
Baden
Zip:
5404
Country:
Switzerland
Status:
Recruiting
Contact:
Last name:
Sacha Rothschild, Site 0077
Phone:
0041564862762
Facility:
Name:
Local Institution - 0086
Address:
City:
Yenimahalle
Zip:
06200
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0086
Facility:
Name:
Local Institution - 0088
Address:
City:
Adana
Zip:
01140
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0088
Facility:
Name:
Local Institution - 0084
Address:
City:
Ankara
Zip:
06010
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0084
Facility:
Name:
Local Institution - 0087
Address:
City:
Istanbul
Zip:
34214
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0087
Facility:
Name:
Local Institution - 0097
Address:
City:
Istanbul
Zip:
34440
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0097
Facility:
Name:
Local Institution - 0083
Address:
City:
Istanbul
Zip:
34899
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0083
Facility:
Name:
Local Institution - 0085
Address:
City:
Sakarya
Zip:
0
Country:
Turkey
Status:
Not yet recruiting
Contact:
Last name:
Site 0085
Start date:
December 21, 2023
Completion date:
January 27, 2031
Lead sponsor:
Agency:
Bristol-Myers Squibb
Agency class:
Industry
Collaborator:
Agency:
Zai Lab (Shanghai) Co., Ltd.
Agency class:
Industry
Source:
Bristol-Myers Squibb
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06140836
https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html
https://www.bmsclinicaltrials.com/us/en/clinical-trials/NCT06140836.html
