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Trial Title:
A Comparative Clinical Study to Determine the Optimal Initial Therapy for Multiple Myeloma
NCT ID:
NCT06151717
Condition:
Multiple Myeloma
Conditions: Official terms:
Multiple Myeloma
Neoplasms, Plasma Cell
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Prospective
Intervention:
Intervention type:
Other
Intervention name:
Non-Interventional Study
Description:
Non-interventional study
Arm group label:
Observational
Summary:
This study evaluates the outcomes of patients undergoing initial therapy for multiple
myeloma.
Detailed description:
PRIMARY OBJECTIVE:
I. Compare the overall survival between bortezomib, lenalidomide and dexamethasone (VRd),
daratumumab, lenalidomide and dexamethasone (DRd) and daratumumab, bortezomib,
lenalidomide and dexamethasone (DVRd) used as initial therapy for patients with newly
diagnosed MM.
OUTLINE: This is an observational study.
Patients have their medical records reviewed on study.
Criteria for eligibility:
Study pop:
Patients with previously untreated multiple myeloma
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- Previously untreated active multiple myeloma starting a new treatment for the
disease with one of the three established treatment regimens: VRd (bortezomib,
lenalidomide, dexamethasone), DRd (daratumumab lenalidomide dexamethasone), or DVRd
(daratumumab, bortezomib, lenalidomide, and dexamethasone)
- No prior treatment for myeloma
- Not receiving concurrent treatment for another active malignancy
- No more than 3 months from start of treatment
Exclusion Criteria:
- Does not meet all inclusion criteria
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Mayo Clinic in Arizona
Address:
City:
Scottsdale
Zip:
85259
Country:
United States
Status:
Recruiting
Contact:
Last name:
Clinical Trials Referral Office
Phone:
855-776-0015
Email:
mayocliniccancerstudies@mayo.edu
Contact backup:
Last name:
Saurabh Chhabra, MD
Facility:
Name:
Mayo Clinic in Florida
Address:
City:
Jacksonville
Zip:
32224-9980
Country:
United States
Status:
Recruiting
Contact:
Last name:
Clinical Trials Referral Office
Phone:
855-776-0015
Email:
mayocliniccancerstudies@mayo.edu
Contact backup:
Last name:
Sikander Ailawadhi, M.D.
Facility:
Name:
Mayo Clinic in Rochester
Address:
City:
Rochester
Zip:
55905
Country:
United States
Status:
Recruiting
Contact:
Last name:
Clinical Trials Referral Office
Phone:
855-776-0015
Email:
mayocliniccancerstudies@mayo.edu
Contact backup:
Last name:
Shaji K. Kumar, MD
Facility:
Name:
Mayo Clinic Health System-Franciscan Healthcare
Address:
City:
La Crosse
Zip:
54601
Country:
United States
Status:
Not yet recruiting
Contact:
Last name:
Clinical Trials Referral Office
Phone:
855-776-0015
Email:
mayocliniccancerstudies@mayo.edu
Contact backup:
Last name:
Anna C. Jones, MD
Start date:
September 21, 2023
Completion date:
December 12, 2025
Lead sponsor:
Agency:
Mayo Clinic
Agency class:
Other
Source:
Mayo Clinic
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06151717
https://www.mayo.edu/research/clinical-trials
