Trial Title:
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide
NCT ID:
NCT06208150
Condition:
Relapsed or Refractory Multiple Myeloma
Conditions: Official terms:
Multiple Myeloma
Neoplasms, Plasma Cell
Dexamethasone
Bortezomib
Pomalidomide
Elotuzumab
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
Talquetamab
Description:
Talquetamab will be administered as a SC injection.
Arm group label:
Arm A: Talquetamab + Pomalidomide (Tal-P)
Arm group label:
Arm B: Talquetamab + Teclistamab (Tal-Tec)
Other name:
JNJ-64407564
Other name:
Talvey
Intervention type:
Drug
Intervention name:
Pomalidomide
Description:
Pomalidomide will be administered orally.
Arm group label:
Arm A: Talquetamab + Pomalidomide (Tal-P)
Arm group label:
Arm C: Elotuzumab+ Pomalidomide+Dexamethasone (EPd) or Pomalidomide+Bortezomib+Dexamethasone (PVd)
Other name:
Pomalyst
Other name:
Imnovid
Intervention type:
Drug
Intervention name:
Teclistamab
Description:
Teclistamab will be administered as a SC injection.
Arm group label:
Arm B: Talquetamab + Teclistamab (Tal-Tec)
Other name:
JNJ-64007957
Other name:
Tecvayli
Intervention type:
Drug
Intervention name:
Elotuzumab
Description:
Elotuzumab will be administered intravenously.
Arm group label:
Arm C: Elotuzumab+ Pomalidomide+Dexamethasone (EPd) or Pomalidomide+Bortezomib+Dexamethasone (PVd)
Other name:
Empliciti
Intervention type:
Drug
Intervention name:
Dexamethasone
Description:
Dexamethasone will be administered either orally or intravenously.
Arm group label:
Arm A: Talquetamab + Pomalidomide (Tal-P)
Arm group label:
Arm B: Talquetamab + Teclistamab (Tal-Tec)
Arm group label:
Arm C: Elotuzumab+ Pomalidomide+Dexamethasone (EPd) or Pomalidomide+Bortezomib+Dexamethasone (PVd)
Intervention type:
Drug
Intervention name:
Bortezomib
Description:
Bortezomib will be administered as a SC injection.
Arm group label:
Arm C: Elotuzumab+ Pomalidomide+Dexamethasone (EPd) or Pomalidomide+Bortezomib+Dexamethasone (PVd)
Other name:
Velcade
Summary:
The purpose of this study is to compare the effectiveness of either talquetamab plus
pomalidomide (Tal-P) or talquetamab plus teclistamab (Tal-Tec) with elotuzumab,
pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone
(PVd).
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Documented multiple myeloma as defined by the criteria below: (a) multiple myeloma
diagnosis according to the international myeloma working group (IMWG) diagnostic
criteria (b) measurable disease at screening as assessed by central laboratory,
defined by any of the following: (i) serum M-protein level greater than or equal to
(>=) 0.5 gram per deciliter (g/dL); or (ii) urine M-protein level >= 200 milligram
(mg) per 24 hours; or (iii) light chain multiple myeloma without measurable
M-protein in the serum or the urine: serum immunoglobulin (Ig) free light chain
(FLC) >= 10 milligrams per deciliter (mg/dL) and abnormal serum Ig kappa lambda FLC
ratio
- Relapsed or refractory disease as defined below: a) Relapsed disease is defined as
an initial response to prior treatment, followed by confirmed progressive disease
(PD) by IMWG criteria greater than (>) 60 days after cessation of treatment. b)
Refractory disease is defined as less than (<) 25 percent (%) reduction in M-protein
or confirmed PD by IMWG criteria during previous treatment or less than or equal to
(<=) 60 days after cessation of treatment
- Documented evidence of PD or failure to achieve a minimal response to the last line
of therapy based on investigator's determination of response by IMWG criteria on or
after their last regimen
- Have an Eastern Cooperative Oncology Group (ECOG) performance status score of 0, 1,
or 2 at screening and immediately prior to the start of administration of study
treatment
- A participant must agree not to be pregnant, breastfeeding, or planning to become
pregnant while enrolled in this study or within 6months after the last dose of study
treatment
Exclusion Criteria:
- Contraindications or life-threatening allergies, hypersensitivity, or intolerance to
any study drug or its excipients
- Stroke, transient ischemic attack, or seizure within 6 months prior to signing
informed consent form (ICF)
- Major surgery or had significant traumatic injury within 2 weeks prior to the start
of administration of study treatment, or will not have fully recovered from surgery,
or has major surgery planned during the time the participant is expected to be
treated in the study or within 2 weeks after administration of the last dose of
study treatment
- A maximum cumulative dose of corticosteroids of >=140 mg of prednisone or equivalent
within 14-day period before the first dose of study drug
- Known active central nervous system (CNS) involvement or exhibits clinical signs of
meningeal involvement of multiple myeloma. If either is suspected, negative whole
brain magnetic resonance imaging (MRI) and lumbar cytology are required
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Yale University School Of Medicine
Address:
City:
New Haven
Zip:
06519
Country:
United States
Status:
Recruiting
Facility:
Name:
Memorial Healthcare System
Address:
City:
Hollywood
Zip:
33021
Country:
United States
Status:
Recruiting
Facility:
Name:
Kootenai Health
Address:
City:
Coeur d'Alene
Zip:
83814
Country:
United States
Status:
Recruiting
Facility:
Name:
Mission Cancer and Blood Medical Oncology and Hematology Associates of Iowa
Address:
City:
Des Moines
Zip:
50309
Country:
United States
Status:
Recruiting
Facility:
Name:
Norton Cancer Institute
Address:
City:
Louisville
Zip:
40207
Country:
United States
Status:
Recruiting
Facility:
Name:
Ascension Providence Hospital
Address:
City:
Southfield
Zip:
48075
Country:
United States
Status:
Recruiting
Facility:
Name:
Regions Hospital
Address:
City:
Saint Paul
Zip:
55101
Country:
United States
Status:
Recruiting
Facility:
Name:
Roswell Park Cancer Institute
Address:
City:
Buffalo
Zip:
14263
Country:
United States
Status:
Recruiting
Facility:
Name:
SUNY Upstate Medical University
Address:
City:
Syracuse
Zip:
13210
Country:
United States
Status:
Recruiting
Facility:
Name:
Louis Stokes Cleveland VA Med Ctr
Address:
City:
Cleveland
Zip:
44106
Country:
United States
Status:
Recruiting
Facility:
Name:
Cleveland Clinic
Address:
City:
Cleveland
Zip:
44195
Country:
United States
Status:
Recruiting
Facility:
Name:
Oregon Health And Science University
Address:
City:
Portland
Zip:
97239
Country:
United States
Status:
Recruiting
Facility:
Name:
Thomas Jefferson University
Address:
City:
Philadelphia
Zip:
19107-4215
Country:
United States
Status:
Recruiting
Facility:
Name:
West Penn Hospital
Address:
City:
Pittsburgh
Zip:
15224
Country:
United States
Status:
Recruiting
Facility:
Name:
University Of Pittsburgh Medical Center UPMC Hillman Cancer Center
Address:
City:
Pittsburgh
Zip:
15232
Country:
United States
Status:
Recruiting
Facility:
Name:
Bon Secours Saint Francis Cancer Center
Address:
City:
Greenville
Zip:
29607
Country:
United States
Status:
Recruiting
Facility:
Name:
Houston Methodist Neal Cancer Center at Texas Medical Center
Address:
City:
Houston
Zip:
77030
Country:
United States
Status:
Recruiting
Facility:
Name:
Swedish Cancer Institute
Address:
City:
Seattle
Zip:
98104
Country:
United States
Status:
Recruiting
Facility:
Name:
Fundaleu
Address:
City:
Buenos Aires
Zip:
C1114AAP
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Hospital Aleman
Address:
City:
Buenos Aires
Zip:
C1118AAT
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Hospital Britanico de Buenos Aires
Address:
City:
Ciudad Autonoma de Buenos Aires
Zip:
C1280AEB
Country:
Argentina
Status:
Recruiting
Facility:
Name:
Royal Adelaide Hospital
Address:
City:
Adelaide
Zip:
5000
Country:
Australia
Status:
Recruiting
Facility:
Name:
Box Hill Hospital
Address:
City:
Box Hill
Zip:
3128
Country:
Australia
Status:
Recruiting
Facility:
Name:
St Vincents Hospital
Address:
City:
Darlinghurst
Zip:
2010
Country:
Australia
Status:
Recruiting
Facility:
Name:
St Vincents Hospital Melbourne
Address:
City:
Fitzroy
Zip:
3065
Country:
Australia
Status:
Recruiting
Facility:
Name:
Gold Coast University Hospital
Address:
City:
Southport
Zip:
4215
Country:
Australia
Status:
Recruiting
Facility:
Name:
Perth Blood Institute
Address:
City:
West Perth
Zip:
6005
Country:
Australia
Status:
Recruiting
Facility:
Name:
Wollongong Hospital
Address:
City:
Wollongong
Zip:
2500
Country:
Australia
Status:
Recruiting
Facility:
Name:
LKH - Universitätsklinikum der PMU Salzburg
Address:
City:
Salzburg
Zip:
05020
Country:
Austria
Status:
Recruiting
Facility:
Name:
Grand Hopital de Charleroi, site Notre Dame
Address:
City:
Charleroi
Zip:
6000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Ziekenhuis Oost-Limburg
Address:
City:
Genk
Zip:
3600
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Ghent University Hospital
Address:
City:
Gent
Zip:
9000
Country:
Belgium
Status:
Recruiting
Facility:
Name:
AZ Nikolaas - Campus Sint-Niklaas Moerland
Address:
City:
Sint-Niklaas
Zip:
9100
Country:
Belgium
Status:
Recruiting
Facility:
Name:
Cetus Oncologia
Address:
City:
Belo Horizonte
Zip:
30110-022
Country:
Brazil
Status:
Recruiting
Facility:
Name:
DF Star
Address:
City:
Brasilia
Zip:
70390-140
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Fundacao Universidade de Caxias do Sul
Address:
City:
Caxias do Sul
Zip:
95070 560
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital Erasto Gaertner- Liga Paranaense de Combate ao Cancer
Address:
City:
Curitiba
Zip:
81520-060
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Hospital De Clinicas De Porto Alegre
Address:
City:
Porto Alegre
Zip:
90035-903
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Instituto D Or de Pesquisa e Ensino IDOR
Address:
City:
Recife
Zip:
50070-480
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI)
Address:
City:
Rio de Janeiro
Zip:
22793-080
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base
Address:
City:
Sao Jose do Rio Preto
Zip:
15090 000
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Real e Benemerita Associacao Portuguesa de Beneficencia
Address:
City:
Sao Paulo
Zip:
01323-001
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Fundacao Antonio Prudente A C Camargo Cancer Center
Address:
City:
Sao Paulo
Zip:
01509 900
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Clinica Medica Sao Germano S/S LTDA
Address:
City:
Sao Paulo
Zip:
04537-081
Country:
Brazil
Status:
Recruiting
Facility:
Name:
Arthur J. E. Child Comprehensive Cancer Centre
Address:
City:
Calgary
Zip:
T2N 5G2
Country:
Canada
Status:
Recruiting
Facility:
Name:
British Columbia Cancer Agency
Address:
City:
Vancouver
Zip:
V5Z4E6
Country:
Canada
Status:
Recruiting
Facility:
Name:
Nova Scotia Health Authority
Address:
City:
Halifax
Zip:
B3H 1V7
Country:
Canada
Status:
Recruiting
Facility:
Name:
Juravinski Cancer Centre
Address:
City:
Hamilton
Zip:
L8V5C2
Country:
Canada
Status:
Recruiting
Facility:
Name:
University Health Network UHN Princess Margaret Cancer Centre
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Facility:
Name:
CIUSSS de l Est de l Ile de Montreal Installation Hopital Maisonneuve Rosemont
Address:
City:
Montreal
Zip:
H1T 2M4
Country:
Canada
Status:
Recruiting
Facility:
Name:
Saskatoon Cancer Centre
Address:
City:
Saskatoon
Zip:
S7N 4H4
Country:
Canada
Status:
Recruiting
Facility:
Name:
Beijing Chaoyang Hospital
Address:
City:
Beijing
Zip:
100020
Country:
China
Status:
Recruiting
Facility:
Name:
Peking University First Hospital
Address:
City:
Beijing
Zip:
100034
Country:
China
Status:
Recruiting
Facility:
Name:
Peking University People s Hospital
Address:
City:
Beijing
Zip:
100044
Country:
China
Status:
Recruiting
Facility:
Name:
The Second Xiangya Hospital of Central South Hospital
Address:
City:
Changsha
Zip:
410011
Country:
China
Status:
Recruiting
Facility:
Name:
Changzhou No 2 Peoples Hospital
Address:
City:
Changzhou
Zip:
213000
Country:
China
Status:
Recruiting
Facility:
Name:
Sichuan Provincial Peoples Hospital
Address:
City:
Chengdu
Zip:
610032
Country:
China
Status:
Recruiting
Facility:
Name:
Fujian Meidical University Union Hospital
Address:
City:
Fuzhou
Zip:
350001
Country:
China
Status:
Recruiting
Facility:
Name:
Sun Yat-Sen University Cancer Center
Address:
City:
Guangzhou
Zip:
510060
Country:
China
Status:
Recruiting
Facility:
Name:
Nanfang Hospital of Southern Medical Hospital
Address:
City:
Guangzhou
Zip:
510515
Country:
China
Status:
Recruiting
Facility:
Name:
First hospital affiliated of Zhejiang Medical university
Address:
City:
Hangzhou
Zip:
310003
Country:
China
Status:
Recruiting
Facility:
Name:
The Second Affiliated Hospital of Zhejiang University College of Medicine
Address:
City:
Hangzhou
Zip:
310009
Country:
China
Status:
Recruiting
Facility:
Name:
Qilu Hospital of Shandong University
Address:
City:
Jinan
Zip:
250012
Country:
China
Status:
Recruiting
Facility:
Name:
The First Affiliated Hospital of NanChang University
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Recruiting
Facility:
Name:
Nanjing Drum Tower Hospital
Address:
City:
Nanjing
Zip:
210008
Country:
China
Status:
Recruiting
Facility:
Name:
Ruijing Hospital Affiliated To Shanghai Jiaotong University School Of Medicine
Address:
City:
Shanghai
Zip:
200025
Country:
China
Status:
Recruiting
Facility:
Name:
Tongji Hospital of Tongji University
Address:
City:
Shanghai
Zip:
200065
Country:
China
Status:
Recruiting
Facility:
Name:
Shanghai Fourth People s Hospital
Address:
City:
Shanghai
Zip:
200434
Country:
China
Status:
Recruiting
Facility:
Name:
Shengjing Hospital Of China Medical University
Address:
City:
Shenyang
Zip:
110055
Country:
China
Status:
Recruiting
Facility:
Name:
Peking University Shenzhen Hospital
Address:
City:
Shenzhen
Zip:
518036
Country:
China
Status:
Recruiting
Facility:
Name:
First Affiliated Hospital SooChow University
Address:
City:
Su Zhou
Zip:
215005
Country:
China
Status:
Recruiting
Facility:
Name:
Tianjin Medical University Cancer Institute and Hospital
Address:
City:
Tianjin
Zip:
30060
Country:
China
Status:
Recruiting
Facility:
Name:
The First Affiliated Hospital of Wenzhou Medical University
Address:
City:
Wenzhou
Zip:
325000
Country:
China
Status:
Recruiting
Facility:
Name:
Tongji Hospital, Tongji Medical College of HUST
Address:
City:
Wuhan
Zip:
430030
Country:
China
Status:
Recruiting
Facility:
Name:
The Second Affiliated Hospital of Xi'an Jiaotong University
Address:
City:
Xi'an
Zip:
710004
Country:
China
Status:
Recruiting
Facility:
Name:
Fakultni nemocnice Brno
Address:
City:
Brno - Bohunice
Zip:
625 00
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Fakultni nemocnice Hradec Kralove
Address:
City:
Hradec Kralove
Zip:
500 05
Country:
Czechia
Status:
Recruiting
Facility:
Name:
University Hospital Olomouc
Address:
City:
Olomouc
Zip:
779 00
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Fakultni Nemocnice Ostrava
Address:
City:
Ostrava
Zip:
708 52
Country:
Czechia
Status:
Recruiting
Facility:
Name:
Aarhus University Hospital
Address:
City:
Aarhus
Zip:
8200
Country:
Denmark
Status:
Recruiting
Facility:
Name:
Odense University Hospital
Address:
City:
Odense C
Zip:
5000
Country:
Denmark
Status:
Recruiting
Facility:
Name:
Vejle Hospital
Address:
City:
Vejle
Zip:
7100
Country:
Denmark
Status:
Recruiting
Facility:
Name:
Hopital Claude Huriez
Address:
City:
Lille
Zip:
59000
Country:
France
Status:
Recruiting
Facility:
Name:
CHU de Limoges Hopital Dupuytren
Address:
City:
Limoges
Zip:
87042
Country:
France
Status:
Recruiting
Facility:
Name:
Institut Paoli Calmettes
Address:
City:
Marseille
Zip:
13009
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Nantes
Address:
City:
Nantes
Zip:
44093
Country:
France
Status:
Recruiting
Facility:
Name:
Hopital Saint Louis
Address:
City:
Paris
Zip:
75010
Country:
France
Status:
Recruiting
Facility:
Name:
CHU de Bordeaux - Hospital Haut-Leveque
Address:
City:
Pessac Cedex
Zip:
33604
Country:
France
Status:
Recruiting
Facility:
Name:
CHU Lyon Sud
Address:
City:
Pierre Benite
Zip:
69495
Country:
France
Status:
Recruiting
Facility:
Name:
Institut de Cancerologie Strasbourg Europe ICANS
Address:
City:
Strasbourg
Zip:
67200
Country:
France
Status:
Recruiting
Facility:
Name:
Institut Universitaire du Cancer Toulouse Oncopole
Address:
City:
Toulouse Cedex 9
Zip:
31100
Country:
France
Status:
Recruiting
Facility:
Name:
CHRU Tours Hopital Bretonneau
Address:
City:
TOURS Cedex 01
Zip:
37044
Country:
France
Status:
Recruiting
Facility:
Name:
Klinikum Augsburg
Address:
City:
Augsburg
Zip:
86156
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Halle Saale
Address:
City:
Halle (Saale)
Zip:
06120
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Heidelberg
Address:
City:
Heidelberg
Zip:
69120
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Magdeburg A.oe.R
Address:
City:
Magdeburg
Zip:
39120
Country:
Germany
Status:
Recruiting
Facility:
Name:
Klinikum rechts der Isar der TU Muenchen
Address:
City:
München
Zip:
81675
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Tuebingen
Address:
City:
Tuebingen
Zip:
72076
Country:
Germany
Status:
Recruiting
Facility:
Name:
Universitaetsklinikum Wuerzburg
Address:
City:
Würzburg
Zip:
97080
Country:
Germany
Status:
Recruiting
Facility:
Name:
251 Airforces Hospital
Address:
City:
Athens
Zip:
115 25
Country:
Greece
Status:
Recruiting
Facility:
Name:
Alexandra General Hospital of Athens
Address:
City:
Athens
Zip:
115 28
Country:
Greece
Status:
Recruiting
Facility:
Name:
Anticancer Hospital of Thessaloniki Theageneio
Address:
City:
Thessaloniki
Zip:
546 39
Country:
Greece
Status:
Recruiting
Facility:
Name:
Semmelweis Egyetem, Belgyogyaszati es Hematologiai Klinika
Address:
City:
Budapest
Zip:
1088
Country:
Hungary
Status:
Recruiting
Facility:
Name:
Szabolcs Szatmar Bereg Varmegyei Oktatokorhaz
Address:
City:
Nyiregyhaza
Zip:
4400
Country:
Hungary
Status:
Recruiting
Facility:
Name:
Pecsi Tudomanyegyetem Klinikai Kozpont
Address:
City:
Pecs
Zip:
7624
Country:
Hungary
Status:
Recruiting
Facility:
Name:
Fortis Memorial Research Institute
Address:
City:
Gurgaon
Zip:
122002
Country:
India
Status:
Recruiting
Facility:
Name:
Sanjay Gandhi Postgraduate Institute of Medical Sciences
Address:
City:
Lucknow
Zip:
226014
Country:
India
Status:
Recruiting
Facility:
Name:
Deenanath Mangeshkar Hospital and Research Centre
Address:
City:
Pune
Zip:
411004
Country:
India
Status:
Recruiting
Facility:
Name:
Shamir Medical Center Assaf Harofeh
Address:
City:
Be'er Ya'akov
Zip:
70300
Country:
Israel
Status:
Recruiting
Facility:
Name:
Carmel Medical Center
Address:
City:
Haifa
Zip:
3436212
Country:
Israel
Status:
Recruiting
Facility:
Name:
Rabin Medical center - Petah-Tikva
Address:
City:
Petah-Tikva
Zip:
49100
Country:
Israel
Status:
Recruiting
Facility:
Name:
Sheba Medical Center
Address:
City:
Ramat Gan
Zip:
52621
Country:
Israel
Status:
Recruiting
Facility:
Name:
Tel Aviv Sourasky Medical Center
Address:
City:
Tel Aviv-Yafo
Zip:
64239
Country:
Israel
Status:
Recruiting
Facility:
Name:
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo Alessandria
Address:
City:
Alessandria
Zip:
15121
Country:
Italy
Status:
Recruiting
Facility:
Name:
oncologia medica - Oncology
Address:
City:
Brindisi
Zip:
72100
Country:
Italy
Status:
Recruiting
Facility:
Name:
ARNAS Garibaldi P O Nesima
Address:
City:
Catania
Zip:
95122
Country:
Italy
Status:
Recruiting
Facility:
Name:
Ospedale Policlinico San Martino IRCCS
Address:
City:
Genova
Zip:
16132
Country:
Italy
Status:
Recruiting
Facility:
Name:
Asst Ovest Milanese - Ospedale Di Legnano
Address:
City:
Legnano
Zip:
20025
Country:
Italy
Status:
Recruiting
Facility:
Name:
Fondazione IRCCS Ca Granda Ospedale Policlinico Di Milano
Address:
City:
Milano
Zip:
20122
Country:
Italy
Status:
Recruiting
Facility:
Name:
IRCCS Ospedale San Raffaele
Address:
City:
Milano
Zip:
20132
Country:
Italy
Status:
Recruiting
Facility:
Name:
Fondazione IRCCS Policlinico San Matteo
Address:
City:
Pavia
Zip:
27100
Country:
Italy
Status:
Recruiting
Facility:
Name:
Presidio Ospedaliero Pescara
Address:
City:
Pescara
Zip:
65124
Country:
Italy
Status:
Recruiting
Facility:
Name:
Ospedale S. Maria Delle Croci
Address:
City:
Ravenna
Zip:
48121
Country:
Italy
Status:
Recruiting
Facility:
Name:
Oncologia Medica-Città Della Salute E Della Scienza Di Torino
Address:
City:
Torino
Zip:
10126
Country:
Italy
Status:
Recruiting
Facility:
Name:
Azienda Ospedaliera Universitaria Integrata Verona
Address:
City:
Verona
Zip:
37134
Country:
Italy
Status:
Recruiting
Facility:
Name:
Juntendo University Hospital
Address:
City:
Bunkyo Ku
Zip:
113 8431
Country:
Japan
Status:
Recruiting
Facility:
Name:
Fukuoka University Hospital
Address:
City:
Fukuoka
Zip:
814-0180
Country:
Japan
Status:
Recruiting
Facility:
Name:
Kanazawa University Hospital
Address:
City:
Kanazawa
Zip:
920-8641
Country:
Japan
Status:
Recruiting
Facility:
Name:
University Hospital Kyoto Prefectural University of Medicine
Address:
City:
Kyoto
Zip:
602-8566
Country:
Japan
Status:
Recruiting
Facility:
Name:
National Hospital Organization Nagasaki Medical Center
Address:
City:
Nagasaki
Zip:
856-8562
Country:
Japan
Status:
Recruiting
Facility:
Name:
Japanese Red Cross Narita Hospital
Address:
City:
Narita
Zip:
286-8523
Country:
Japan
Status:
Recruiting
Facility:
Name:
Niigata Cancer Center Hospital
Address:
City:
Niigata
Zip:
951-8566
Country:
Japan
Status:
Recruiting
Facility:
Name:
Hyogo Medical University Hospital
Address:
City:
Nishinomiya-shi
Zip:
663-8501
Country:
Japan
Status:
Recruiting
Facility:
Name:
Japanese Red Cross Osaka Hospital
Address:
City:
Osaka
Zip:
543-0027
Country:
Japan
Status:
Recruiting
Facility:
Name:
Sapporo City General Hospital
Address:
City:
Sapporo
Zip:
060-8604
Country:
Japan
Status:
Recruiting
Facility:
Name:
Tohoku University Hospital
Address:
City:
Sendai
Zip:
980 8574
Country:
Japan
Status:
Recruiting
Facility:
Name:
Japanese Red Cross Medical Center
Address:
City:
Shibuya-ku
Zip:
150-8935
Country:
Japan
Status:
Recruiting
Facility:
Name:
Iwate Medical University Hospital
Address:
City:
Shiwa-gun
Zip:
028-3695
Country:
Japan
Status:
Recruiting
Facility:
Name:
Osaka University Hospital
Address:
City:
Suita-City
Zip:
565-0871
Country:
Japan
Status:
Recruiting
Facility:
Name:
Shizuoka Cancer Center
Address:
City:
Sunto-gun
Zip:
411-8777
Country:
Japan
Status:
Recruiting
Facility:
Name:
The Cancer Institute Hospital of JFCR
Address:
City:
Tokyo
Zip:
135-8550
Country:
Japan
Status:
Recruiting
Facility:
Name:
Tottori University Hospital
Address:
City:
Tottori
Zip:
683-0824
Country:
Japan
Status:
Recruiting
Facility:
Name:
University of Tsukuba Hospital
Address:
City:
Tsukuba
Zip:
305 8576
Country:
Japan
Status:
Recruiting
Facility:
Name:
Kanagawa Cancer Center
Address:
City:
Yokohama City
Zip:
241 8515
Country:
Japan
Status:
Recruiting
Facility:
Name:
Dong-A University Hospital
Address:
City:
Busan
Zip:
49201
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Pusan National University Hospital
Address:
City:
Busan
Zip:
49241
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Chonnam National University Hwasun Hospital
Address:
City:
Jeollanam-do
Zip:
58128
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Seoul National University Hospital
Address:
City:
Seoul
Zip:
03080
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Samsung Medical Center
Address:
City:
Seoul
Zip:
06351
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
The Catholic University of Korea Seoul St Mary s Hospital
Address:
City:
Seoul
Zip:
06591
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Ulsan University Hospital
Address:
City:
Ulsan
Zip:
44033
Country:
Korea, Republic of
Status:
Recruiting
Facility:
Name:
Flevoziekenhuis
Address:
City:
Almere
Zip:
1315RA
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Haga ziekenhuis
Address:
City:
Den Haag
Zip:
2545 CH
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Catharinaziekenhuis
Address:
City:
Eindhoven
Zip:
5623 EJ
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
St. Antonius Ziekenhuis Nieuwegein
Address:
City:
Nieuwegein
Zip:
3435 CM
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Isala Kliniek
Address:
City:
Zwolle
Zip:
8025 AB
Country:
Netherlands
Status:
Recruiting
Facility:
Name:
Wojewodzki Szpital Specjalistyczny
Address:
City:
Biala Podlaska
Zip:
21 500
Country:
Poland
Status:
Recruiting
Facility:
Name:
Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza
Address:
City:
Brzozow
Zip:
36-200
Country:
Poland
Status:
Recruiting
Facility:
Name:
Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach
Address:
City:
Kielce
Zip:
25-734
Country:
Poland
Status:
Recruiting
Facility:
Name:
Centrum Onkologii Ziemii Lubelskiej
Address:
City:
Lublin
Zip:
20-090
Country:
Poland
Status:
Recruiting
Facility:
Name:
Uniwersytecki Szpital Kliniczny Nr 1 PUM im prof Tadeusza Sokolowskiego w Szczecinie
Address:
City:
Szczecin
Zip:
71-252
Country:
Poland
Status:
Recruiting
Facility:
Name:
Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu
Address:
City:
Wroclaw
Zip:
50-367
Country:
Poland
Status:
Recruiting
Facility:
Name:
King Abdullah International Medical Research Center (KAIMRC)
Address:
City:
Riyadh
Zip:
11481
Country:
Saudi Arabia
Status:
Recruiting
Facility:
Name:
King Faisal Specialist Hospital & Research Center
Address:
City:
Riyadh
Zip:
11564
Country:
Saudi Arabia
Status:
Recruiting
Facility:
Name:
King Fahad Medical City
Address:
City:
Riyadh
Zip:
12231
Country:
Saudi Arabia
Status:
Recruiting
Facility:
Name:
Hosp. de Cabuenes
Address:
City:
Asturias
Zip:
33394
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp Univ Vall D Hebron
Address:
City:
Barcelona
Zip:
08035
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. de Burgos
Address:
City:
Burgos
Zip:
09003
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. San Pedro de Alcantara
Address:
City:
Cáceres
Zip:
10003
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Virgen de Las Nieves
Address:
City:
Granada
Zip:
18014
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Lucus Augusti
Address:
City:
Lugo
Zip:
27003
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. La Paz
Address:
City:
Madrid
Zip:
28046
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Son Espases
Address:
City:
Palma de Mallorca
Zip:
07120
Country:
Spain
Status:
Recruiting
Facility:
Name:
Clinica Univ. de Navarra
Address:
City:
Pamplona
Zip:
31008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Complejo Hosp de Navarra - Hosp de Navarra
Address:
City:
Pamplona
Zip:
31008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp Clinico Univ de Salamanca
Address:
City:
Salamanca
Zip:
37007
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Donostia
Address:
City:
San Sebastian
Zip:
20014
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Univ. Marques de Valdecilla
Address:
City:
Santander
Zip:
39008
Country:
Spain
Status:
Recruiting
Facility:
Name:
Hosp. Clinico Univ. de Santiago
Address:
City:
Santiago de Compostela
Zip:
15706
Country:
Spain
Status:
Recruiting
Facility:
Name:
Skanes universitetssjukhus
Address:
City:
Lund
Zip:
221 85
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Norrlands Universitetssjukhus
Address:
City:
Umea
Zip:
901 85
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Akademiska Sjukhuset
Address:
City:
Uppsala
Zip:
75185
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Varberg Hospital
Address:
City:
Varberg
Zip:
432 81
Country:
Sweden
Status:
Recruiting
Facility:
Name:
Ankara University Medical Faculty
Address:
City:
Ankara
Zip:
06620
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Liv Hospital Ankara
Address:
City:
Ankara
Zip:
06680
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Pamukkale University Medical Faculty
Address:
City:
Denizli
Zip:
20070
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Medipol University Hospital
Address:
City:
Istanbul
Zip:
34214
Country:
Turkey
Status:
Recruiting
Facility:
Name:
Ondokuz Mayis University
Address:
City:
Samsun
Zip:
55280
Country:
Turkey
Status:
Recruiting
Facility:
Name:
University Hospital of Wales
Address:
City:
Cardiff
Zip:
CF14 4HY
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Ninewells Hospital
Address:
City:
Dundee
Zip:
DD1 9SY
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Nottingham City Hospital
Address:
City:
Nottingham
Zip:
NG5 1PB
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
University Hospitals Plymouth NHS Trust
Address:
City:
Plymouth
Zip:
PL6 8DH
Country:
United Kingdom
Status:
Recruiting
Facility:
Name:
Queen Alexandra Hospital
Address:
City:
Portsmouth
Zip:
PO6 3LY
Country:
United Kingdom
Status:
Recruiting
Start date:
January 22, 2024
Completion date:
June 30, 2030
Lead sponsor:
Agency:
Janssen Research & Development, LLC
Agency class:
Industry
Source:
Janssen Research & Development, LLC
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06208150
