To hear about similar clinical trials, please enter your email below
Trial Title:
Risk Factors for Neuroendocrine Neoplasms
NCT ID:
NCT06282016
Condition:
Neuroendocrine Neoplasm of Lung
Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)
Conditions: Official terms:
Neoplasms
Neuroendocrine Tumors
Lung Neoplasms
Digestive System Neoplasms
Gastrointestinal Neoplasms
Conditions: Keywords:
Neuroendocrine neoplasms
Colorectal cancer
Risk factors
Case-Control Study
Cancer Registry
Study type:
Observational
Overall status:
Not yet recruiting
Study design:
Time perspective:
Retrospective
Intervention:
Intervention type:
Other
Intervention name:
Case-control study (no intervention)
Description:
Observation of risk factors in cases and controls
Arm group label:
Cases
Arm group label:
Controls
Summary:
Recent studies show an increase in neuroendocrine neoplasms, especially for the digestive
tract. Previous studies suggest various risk factors that were observed for various tumor
sites, e.g. a family history of cancer, tobacco and alcohol consumption as well as
metabolic disorders including diabetes and obesity. A risk factor that has been little
studied to date is depressive disorders, which could increase the risk of neuroendocrine
neoplasms either independently or through associated risk behaviors and/or antidepressant
medication. The aim of this study is to identify risk factors for neuroendocrine
neoplasms based on a case-control study in order to better understand the increase of
neuroendocrine neoplasms in recent decades. The study is based on a record linkage of
data from the Bavarian Cancer Registry and data from the Bavarian Association of
Statutory Health Insurance Accredited Physicians. While the data from the Bavarian Cancer
Registry enables the identification of neuroendocrine neoplasms on the basis of
histopathological findings and thus is the basis for selecting cases, the claims data
from the Bavarian Association of Statutory Health Insurance Accredited Physicians
provides the source population as well data on diagnoses and thus enables the
investigation of risk factors.
Criteria for eligibility:
Study pop:
Cases are defined as all persons with a malignant neuroendocrine neoplasm of the
bronchopulmonary or gastroenteropancreatic system diagnosed in 2020 or 2021. Controls are
defined as noncases in the source population of cases, i.e. persons with a statutory
health insurance and at least one outpatient physician contact in Bavaria in 2020 or
2021, whose residence was in Bavaria. Two controls will be sampled for each case.
Sampling method:
Probability Sample
Criteria:
Inclusion Criteria:
- Persons with a statutory health insurance (about 85% of the population) and at least
one outpatient physician contact in Bavaria in 2020 or 2021
- Residence in Bavaria
Exclusion Criteria:
- None
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
Accepts Healthy Volunteers
Start date:
October 15, 2024
Completion date:
August 2025
Lead sponsor:
Agency:
Bavarian Cancer Registry
Agency class:
Other
Collaborator:
Agency:
Bavarian Association of Statutory Health Insurance Accredited Physicians
Agency class:
Other
Source:
Bavarian Cancer Registry
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06282016
