Trial Title:
D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure
NCT ID:
NCT06300177
Condition:
Non Small Cell Lung Cancer
Conditions: Official terms:
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Docetaxel
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Intervention:
Intervention type:
Drug
Intervention name:
D-1553 Tablet
Description:
D-1553 is a KRAS inhibitor.
Arm group label:
D-1553 Tablet
Intervention type:
Drug
Intervention name:
Docetaxel injection
Description:
Docetaxel, is an anti-tumor drug, significantly reduces the number of free tubules by
promoting tubule polymerization into stable microtubules and inhibiting their
depolymerization.
Arm group label:
Docetaxel Injection
Summary:
The purpose of this project is to evaluate progression-free survival (PFS) of D-1553
Tablet versus Docetaxel Injection in subjects with prior standard therapy failure kirsten
rat sarcoma viral oncogene (KRAS) G12C mutation positive locally advanced or metastatic
non small cell lung cancer (NSCLC), progression-free survival (PFS) as assessed by the
Independent Review Committee (IRC) based on RECIST 1.1 was used as the primary endpoint.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Voluntary participation in the study and sign of written informed consent after full
informed consent, willing and able to comply with the study procedures and
requirements specified in the protocol;
- Age greater than or equal to 18 years old; male and female; eastern cooperative
oncology group performance status (ECOG) score 0-1; expected survival period greater
than or equal to 3 months;
- Pathologically confirmed locally advanced, unresectable and / or metastatic
non-small cell lung cancer (stage III b / III c / IV of american joint committee on
cancer (AJCC) 8th);
- Subjects must provide adequate and qualified tumor tissue specimens (surgical
resection samples or puncture / biopsy tissue samples within 2 years prior to
screening) for confirmation of the KRAS G12C mutation in the central laboratory;
- Disease progression or toxicity after previous treatment with first-line anti-PD-1 /
PD-L1 and platinum-containing chemotherapy is not tolerated.Subjects who have clear
medical reasons and can not tolerate anti-PD-1 / PD-L1 therapy or
platinum-containing chemotherapy;
- Having at least one target lesion according to RECIST 1.1;
- Good function of the major organs;
- Female subjects of childbearing age should agree that contraception must be used
during the study and within 6 months after the end of the study; the serum pregnancy
test is negative within 7 days before study enrollment and must be non-lactating
subjects; male subjects should agree that contraception must be used during the
study and within 6 months after the end of the study period.
Exclusion Criteria:
- Treatment with a KRAS G12C mutation inhibitor or docetaxel at any previous time;
- NSCLC with mutations of other driver genes;
- Symptomatic or progressive aggravation of central nervous system metastasis or
cancerous meningitis. Subjects with a history of brain metastasis may be considered
to be selected if they are clinically stable;
- Patients with a previous history of epilepsy;presence of superior vena cava
syndrome;
- Cardiovascular system meets any condition:
1. New York Heart Association (NYHA) Heart Function Grade II and above congestive
heart failure;
2. Severe cardiac arrhythmias requiring medical treatment;
3. Acute myocardial infarction, severe or unstable angina pectoris, coronary or
peripheral artery bypass surgery within 6 months prior to enrollment;
4. Left ventricular ejection fraction (LVEF) <50%;
5. QT interval (QTcF) at prolonged;
6. Hypertension that is not effectively controlled;
- Subjects with stroke or other severe cerebrovascular disease within 6 months before
enrollment;
- History of deep vein thrombosis or any other serious thromboembolism within 3 months
prior to enrollment;
- History of interstitial lung disease, radiation pneumonitis, and immune-associated
pneumonia previously treated with steroids, Or active non-infectious pneumonia with
interstitial lung disease, radiation pneumonia, and immune-related pneumonia during
the screening period, Presence of active tuberculosis, pneumoconiosis or grade 2
other type of pneumonia, or pulmonary function tests confirming severely impaired
pulmonary function;
- Severe bone damage due to tumor bone metastasis may occur at present or after
randomization;
- Active or uncontrolled serious infection (≥grade 2 infection of common toxicity
criteria for adverse events (CTC AE)) or fever of unknown origin > 38.5°C;
- The third space effusion (including pleural effusion, abdominal effusion or
pericardial effusion), poor clinical control or the need for local symptomatic
treatment such as puncture and drainage;
- Known impaired gastrointestinal (GI) function or known GI diseases that may
significantly affect the absorption or metabolism of oral drugs.
Previous history of major surgery in the digestive tract (esophagus, gastrointestinal
tract) that may alter the absorption or inability to swallow drugs in the study
treatment;
- Toxicity of previous antitumor therapy, except alopecia, pigmentation, clinically
insignificant laboratory abnormalities) has not recovered to grade 1, and peripheral
nerve toxicity has not recovered to grade 2 ( CTCAE v5.0);
- Human immunodeficiency virus (HIV) antibody positive, liver cirrhosis or active
viral hepatitis;
- Active syphilis;
- Patients with renal failure requiring hemodialysis or peritoneal dialysis;
- Poor diabetes control [fasting blood glucose (FBG)> 10 mmol/L];
- Previous history of organ transplantation or readiness to undergo organ
transplantation;
- Weight of <40 kg and BMI of <18.5 kg/m2, or weight loss of> 5% within 3 months
before enrollment;
- Major surgical treatment or significant traumatic injury within 4 weeks prior to the
first dose of this study;
- Receiving palliative radiotherapy with local lesions within 2 weeks before the first
dose of this study;
- Pregnant or lactating subjects;
- With the combination of other primary malignancies
- Serious mental or mental illness or history of substance abuse or serious alcohol
abuse;
- Known allergy to the investigational medicinal product or any ingredient in the
formulation;
- Any other significant clinical abnormality or disease that the investigator
considers poses a risk to subject safety or interferes with the medication and
evaluation of the clinical study.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Anhui Province Hospital
Address:
City:
Hefei
Zip:
230002
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Minghong Bao, Master
Phone:
15255187155
Email:
baomh2015@163.com
Facility:
Name:
Cancer Hospital Chinese Academy of Medical Sciences
Address:
City:
Beijing
Zip:
100021
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yan Wang, Doctor
Phone:
13911793771
Email:
wangyanyifu@163.com
Facility:
Name:
Xuanwu Hospital Capital Medical University
Address:
City:
Beijing
Zip:
100053
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yi Zhang, Doctor
Phone:
13141370703
Email:
steven9130@sina.com
Facility:
Name:
Beijing Cancer Hospital
Address:
City:
Beijing
Zip:
100142
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Jian Fang, Bachelor
Phone:
13701224460
Email:
fangjian5555@yeah.net
Facility:
Name:
Peking University Third Hospital
Address:
City:
Beijing
Zip:
100191
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Baoshan Cao, Doctor
Phone:
13641093518
Email:
caobaoshan0711@aliyun.com
Facility:
Name:
Beijing Chest Hospital,Capital Medical University
Address:
City:
Beijing
Zip:
101149
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Tongmei Zhang, Doctor
Phone:
13683016715
Email:
tongmeibj@163.com
Facility:
Name:
The Fifth medical center of Chinese PLA General Hospital
Address:
City:
Beijing
Zip:
222002
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Junxun Ma, Doctor
Phone:
13699262799
Email:
majunxun74@126.com
Facility:
Name:
The Second Affiliated Hospital of Chongqing Medical University
Address:
City:
Chongqing
Zip:
400010
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Zhenzhou Yang, Doctor
Phone:
13883270881
Email:
yangzz1970@163.com
Facility:
Name:
Chongqing Cancer Hospital
Address:
City:
Chongqing
Zip:
400032
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Jianlin Long, Doctor
Phone:
17830326836
Email:
ga.longjianlin@163.com
Facility:
Name:
The Southwest hospital of AMU
Address:
City:
Chongqing
Zip:
400038
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Jianjun Li, Doctor
Phone:
13608319428
Email:
leejjun2007@163.com
Facility:
Name:
Army Medical Center
Address:
City:
Chongqing
Zip:
400042
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Mengxia Li, Doctor
Phone:
18580408265
Email:
707849603@qq.com
Facility:
Name:
Chongqing University Three Gorges Hospital
Address:
City:
Chongqing
Zip:
404100
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Wei Wang, Master
Phone:
13635324483
Email:
19574605@qq.com
Facility:
Name:
Fujian Medical University Union Hospital
Address:
City:
Fuzhou
Zip:
350001
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Peifeng Hou, Doctor
Phone:
13799987620
Email:
717217167@qq.com
Facility:
Name:
The First Affiliated Hospital Of Fujian Medical University
Address:
City:
Fuzhou
Zip:
350005
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Rixiong Wang, Doctor
Phone:
13960758357
Email:
13960758357@163.com
Facility:
Name:
Fujian Cancer Hospital
Address:
City:
Fuzhou
Zip:
350500
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Jing Zhang, Master
Phone:
13809557405
Email:
cfcy813@sina.com
Facility:
Name:
The First Affiliated Hospital of Xiamen University
Address:
City:
Xiamen
Zip:
361003
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Feng Ye, Doctor
Phone:
13860458889
Email:
yefengdoctor@sina.com
Facility:
Name:
Lanzhou University Second Hospital
Address:
City:
Lanzhou
Zip:
730030
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Junnian Shi, Master
Phone:
13919778675
Email:
ldeyyzbgs@lzu.edu.cn
Facility:
Name:
Gansu Provincial Cancer Hospital
Address:
City:
Lanzhou
Zip:
730050
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xiting Liu, Bachelor
Phone:
13893296929
Email:
LXT-0421@163.com
Facility:
Name:
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Address:
City:
Guangzhou
Zip:
510399
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Minghui Wang, Doctor
Phone:
13826276828
Email:
wmingh@mail.sysu.edu.cn
Facility:
Name:
The First Affiliated Hospital of Guangdong Pharmaceutical University
Address:
City:
Guangzhou
Zip:
528405
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xintian Qin, Master
Phone:
13660558820
Email:
xintianqin@126.com
Facility:
Name:
The Affiliated Hospital of Guangdong Medical University
Address:
City:
Zhanjiang
Zip:
524001
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Shujun Li, Master
Phone:
13726913133
Email:
lishujun072@163.com
Facility:
Name:
The Second Affiliated Hospital of Guilin Medical College
Address:
City:
Guilin
Zip:
541199
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Bihui Li, Master
Phone:
18378316283
Email:
lbihui0202@163.com
Facility:
Name:
The First Affiliated Hospital of Guangxi Medical University
Address:
City:
Nanning
Zip:
530020
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Qing Bu, Doctor
Phone:
18277133566
Email:
1332271797@qq.com
Facility:
Name:
Yulin First People's Hospital
Address:
City:
Yulin
Zip:
537000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Haizhen Yi, Master
Phone:
15807851995
Email:
yhz228815@168.com
Facility:
Name:
Guizhou Provincial People's Hospital
Address:
City:
Guiyang
Zip:
550002
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yu Zhang, Doctor
Phone:
18885146684
Email:
248634489@qq.com
Facility:
Name:
The Second Affiliated Hospital of Zunyi Medical University
Address:
City:
Zunyi
Zip:
563000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yuju Bai, Master
Phone:
13984535566
Email:
byj6618@163.com
Facility:
Name:
Hainan Provincial People's Hospital
Address:
City:
Haikou
Zip:
570311
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yongxing Chen, Master
Phone:
13876825536
Email:
chen13876825536@163.com
Facility:
Name:
Affiliated Hospital of Hebei University
Address:
City:
Baoding
Zip:
050031
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Zizheng Song, Master
Phone:
13932268911
Email:
13932268911@163.com
Facility:
Name:
The Affiliated Hospital of Chengde Medical College
Address:
City:
Chengde
Zip:
067028
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Qingshan Li, Bachelor
Phone:
15633142750
Email:
libing200865@126.com
Facility:
Name:
The Fourth Hospital of Hebei Medical University
Address:
City:
Shijiazhuang
Zip:
050011
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yudong Wang, Doctor
Phone:
15931166600
Email:
wyd_999@hebmu.edu.cn
Facility:
Name:
Tangshan People's Hospital
Address:
City:
Tangshan
Zip:
063001
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Junquan Yang, Doctor
Phone:
19131829092
Email:
13313059092@163.com
Facility:
Name:
Affiliated Cancer Hospital of Harbin Medical University
Address:
City:
Harbin
Zip:
150000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Baogang Liu, Doctor
Phone:
13804552752
Email:
liubaogang1962@sina.com
Facility:
Name:
The Second Affiliated Hospital of Harbin Medical University
Address:
City:
Harbin
Zip:
150000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Tao Xin, Doctor
Phone:
13633655999
Email:
xintao1234@263.net
Facility:
Name:
Jiamusi Tuberculosis Hospital(Jiamusi Cancer Hospital)
Address:
City:
Jiamusi
Zip:
154000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Hongmei Sun, Bachelor
Phone:
15344540000
Email:
SHM1357@163.com
Facility:
Name:
Anyang Tumor Hospital
Address:
City:
Anyang
Zip:
455001
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yuanyuan Ji, Master
Phone:
13460856657
Email:
jiyuanyuan666@126.com
Facility:
Name:
The First Affiliated Hospital of Henan University of Science and Technology
Address:
City:
Luoyang
Zip:
471003
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Zhiye Zhang, Master
Phone:
13783100985
Email:
13783100985@163.com
Facility:
Name:
Nanyang second general hospital
Address:
City:
Nanyang
Zip:
473000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Qichuan Wang, Master
Phone:
13838709208
Email:
chuan12616@126.com
Facility:
Name:
The First affiliated Hospital of Nanyang Medical College
Address:
City:
Nanyang
Zip:
473007
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Peng Cheng, Master
Phone:
13782042723
Email:
oncologist@163.com
Facility:
Name:
The First Affiliated Hospital Of Xinxiang Medical Unerversity
Address:
City:
Xinxiang
Zip:
453100
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Weiwei Li, Master
Phone:
13837384916
Email:
13837384916@163.com
Facility:
Name:
Xuchang Central Hospital
Address:
City:
Xuchang
Zip:
461000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Pengyuan Wang, Master
Phone:
13837440693
Email:
wangpengyuan@126.com
Facility:
Name:
Henan Cancer Hospital
Address:
City:
Zhengzhou
Zip:
450008
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yanqiu Zhao, Master
Phone:
13938252350
Email:
13938252350@163.com
Facility:
Name:
The First Affiliated Hospital Zhejiang University School of Medicine
Address:
City:
Zhengzhou
Zip:
450052
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xingya Li, Doctor
Phone:
13838253946
Email:
lixingyavip@163.com
Facility:
Name:
Henan Provincial People's Hospita
Address:
City:
Zhengzhou
Zip:
463599
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Shundong Cang, Doctor
Phone:
13592675836
Email:
cangshundong@163.com
Facility:
Name:
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology
Address:
City:
Wuhan
Zip:
430030
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Qian Chu, Doctor
Phone:
13212760751
Email:
qianchu@tjh.tjmu.edu.cn
Facility:
Name:
Zhongnan hospital of Wuhan University
Address:
City:
Wuhan
Zip:
430071
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Junhong Zhang, Bachelor
Phone:
13638679004
Email:
Zjhzhongnan@163.com
Facility:
Name:
The Second Xiangya Hospital Of Central South University
Address:
City:
Changsha
Zip:
410011
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Fang Ma, Doctor
Phone:
13975806788
Email:
dr_fma@126.com
Facility:
Name:
The Third Xiangya Hospital of Central South University
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xuewen Liu, Doctor
Phone:
18711033808
Email:
aveinliu@163.com
Facility:
Name:
Hunan Cancer Hospital
Address:
City:
Changsha
Zip:
410031
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Bolin Chen, Doctor
Phone:
13787101898
Email:
chenbolin@hnca.org.cn
Facility:
Name:
Hunan Cancer Hospital
Address:
City:
Changsha
Zip:
410031
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yongzhong Luo, Bachelor
Phone:
13607443876
Email:
luoyongzhong@hnca.org.cn
Facility:
Name:
Xiangya Hospital Central South University
Address:
City:
Changsha
Zip:
410119
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Rongrong Zhou, Doctor
Phone:
13875898127
Email:
664990095@qq.com
Facility:
Name:
The first people's hospital of Changzhou
Address:
City:
Changzhou
Zip:
213004
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Mei Ji, Doctor
Phone:
0519-68871123
Email:
jimei@163.com
Facility:
Name:
General Hospital of eastern theater command
Address:
City:
Nanjing
Zip:
210007
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yong Song, Doctor
Phone:
13851761392
Email:
song_yong6310@126.com
Facility:
Name:
Jiangsu Cancer Hospital
Address:
City:
Nanjing
Zip:
210009
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Guohao Xia, Doctor
Phone:
13913976000
Email:
13913976000@163.com
Facility:
Name:
Nantong Tumor Hospital
Address:
City:
Nantong
Zip:
226006
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Junguo Liu, Bachelor
Phone:
13814603295
Email:
jsntzlyy@126.com
Facility:
Name:
Wuxi People's Hospital
Address:
City:
Wuxi
Zip:
214023
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Tao Bian, Doctor
Phone:
13358119859
Email:
biantaophd@126.com
Facility:
Name:
Jiangyin People's Hospital
Address:
City:
Wuxi
Zip:
214400
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Dong Shen, Doctor
Phone:
15961663515
Email:
shendong@ntu.edu.cn
Facility:
Name:
The Affiliated Hospital Of XuZhou Medical University
Address:
City:
Xuzhou
Zip:
221004
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Zhengxiang Han, Doctor
Phone:
18052268612
Email:
cnhzxyq@163.com
Facility:
Name:
Xuzhou Central Hospital
Address:
City:
Xuzhou
Zip:
221009
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xiang Wang, Master
Phone:
18912007930
Email:
wangxiang7726@163.com
Facility:
Name:
Jiangxi Provincial People's Hospital
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Weirong Yao, Doctor
Phone:
13907002901
Email:
13907002901@126.com
Facility:
Name:
The First Affiliated Hospital Of Nanchang University
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Longhua Sun, Doctor
Phone:
18279110112
Email:
48570887@qq.com
Facility:
Name:
Jiangxi Cancer Hospital
Address:
City:
Nanchang
Zip:
330029
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Zhenntian Liu, Master
Phone:
15070083853
Email:
345588506@qq.com
Facility:
Name:
Jilin Cancer Hospital
Address:
City:
Changchun
Zip:
130000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Ying Cheng, Doctor
Phone:
0431-80596003
Email:
jl.cheng@163.com
Facility:
Name:
The First Affiliated Hospital of China Medical University
Address:
City:
Shenyang
Zip:
110002
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yunpeng Liu, Doctor
Phone:
13898865122
Email:
cmu_trial@163.com
Facility:
Name:
Shengjing hospital of China medical university
Address:
City:
Shenyang
Zip:
110022
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Caigang Liu, Doctor
Phone:
18940254967
Email:
liucg@sj-hospital.org
Facility:
Name:
Shandong Cancer Hospitai
Address:
City:
Jinan
Zip:
250117
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Hui Zhu, Doctor
Phone:
15805310022
Email:
drzhuhui@163.com
Facility:
Name:
Jining First People's Hospital
Address:
City:
Jining
Zip:
272011
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Jie Li, Doctor
Phone:
13964921790
Email:
13964921790@139.com
Facility:
Name:
Qingdao Municipal Hospital
Address:
City:
Qingdao
Zip:
266011
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Mi Zhou, Master
Phone:
18561858073
Email:
mi_zhou1978@163.com
Facility:
Name:
The Second Affiliated Hospital of Shandong First Medical University
Address:
City:
Tai'an
Zip:
271000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Haiyan Liu, Master
Phone:
18505387037
Email:
fylhy1998@163.com
Facility:
Name:
Weifang people's Hospital
Address:
City:
Weifang
Zip:
261000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Wei Tan, Master
Phone:
13863659099
Email:
13863659099@126.com
Facility:
Name:
Weihai Municipal Hospital
Address:
City:
Weihai
Zip:
264299
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Fujun Yang, Doctor
Phone:
18660377195
Email:
58500775@qq.com
Facility:
Name:
Ruijin Hospital, Shanghai Jiaotong University School Of Medicine
Address:
City:
Shanghai
Zip:
200025
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Min Zhou, Doctor
Phone:
13681779624
Email:
doctor_zhou_99@163.com
Facility:
Name:
Shanghai Chest Hospital
Address:
City:
Shanghai
Zip:
200030
Country:
China
Status:
Recruiting
Contact:
Last name:
Shun Lu, Doctor
Phone:
13601813062
Email:
shun_lu@hotmail.com
Facility:
Name:
Changzhi People's Hospital
Address:
City:
Changzhi
Zip:
046000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Jun Zhao, Doctor
Phone:
13835578500
Email:
zhaojun380@163.com
Contact backup:
Last name:
Xianping Zhao, Bachelor
Phone:
13453503966
Email:
ZXP13453503966@126.com
Facility:
Name:
Shanxi Provincial Cancer Hospital
Address:
City:
Taiyuan
Zip:
030013
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Wei Guo, Master
Phone:
13834563396
Email:
guowei812@126.com
Facility:
Name:
The First Affiliated Hospital of Xi'An JiaoTong University
Address:
City:
Xi'an
Zip:
710061
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xiaomin Dang, Doctor
Phone:
18991232795
Email:
dxming112@163.com
Facility:
Name:
The Second Affiliated Hospital of Air Force Medical University
Address:
City:
Xian
Zip:
710032
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Haichuan Su, Doctor
Phone:
18629190366
Email:
cntdgcp@163.com
Facility:
Name:
Sichuan Provincial People's Hospital
Address:
City:
Chengdu
Zip:
610072
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Haitao Lan, Doctor
Phone:
18981838376
Email:
lanht@sina.com
Facility:
Name:
The Affiliated Hospital Of Southwest Medical Unerversity
Address:
City:
Luzhou
Zip:
646000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Peirong Ren, Master
Phone:
15883037066
Email:
1097802221@qq.com
Facility:
Name:
Mianyang Central Hospital
Address:
City:
Mianyang
Zip:
621099
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Gang Feng, Doctor
Phone:
18141380968
Email:
15520828768@163.com
Facility:
Name:
The second people's hospital of neijiang
Address:
City:
Neijiang
Zip:
641000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yu Liu, Master
Phone:
13698308655
Email:
13278258@qq.com
Facility:
Name:
Tianjin medical University cancer
Address:
City:
Tianjin
Zip:
300181
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Xiubao Ren, Doctor
Phone:
18622221235
Email:
rwziyi@163.com
Facility:
Name:
The Affiliated Tumor Hospital of Xinjiang Medical University
Address:
City:
Urumqi
Zip:
830054
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Chunling Liu, Master
Phone:
13899931987
Email:
liudeyouxiang66@163.com
Facility:
Name:
Yunnan Cancer Hospital
Address:
City:
Kunming
Zip:
650118
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Runxiang Yang, Master
Phone:
13888876721
Email:
13888876721@163.com
Facility:
Name:
The First Affiliated Hospital Zhejiang University School of Medicine
Address:
City:
Hangzhou
Zip:
310009
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yina Wang, Doctor
Phone:
15957109041
Email:
sinead555@163.com
Facility:
Name:
The Second Affiliated Hospital Zhejiang University School of Medicine
Address:
City:
Hangzhou
Zip:
310009
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Pingli Wang, Doctor
Phone:
13516808409
Email:
W_pl77@163.com
Facility:
Name:
The First Affiliated Hospital of Wenzhou Medical University
Address:
City:
Wenzhou
Zip:
325000
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Yanfan Chen, Doctor
Phone:
13600666600
Email:
chenyf2605@163.com
Start date:
March 28, 2024
Completion date:
December 2027
Lead sponsor:
Agency:
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Agency class:
Industry
Source:
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06300177