Trial Title:
AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2
NCT ID:
NCT06346392
Condition:
Gastric Cancer
Gastroesophageal Junction Cancer
Conditions: Official terms:
Adenocarcinoma
Stomach Neoplasms
Paclitaxel
Docetaxel
Albumin-Bound Paclitaxel
Irinotecan
Apatinib
Ramucirumab
Conditions: Keywords:
Gastric cancer
Gastroesophageal junction cancer
Phase III
Claudin 18.2
AZD0901
Study type:
Interventional
Study phase:
Phase 3
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Intervention model description:
Participants will be randomized in a 1:1:1 ratio to one of the following intervention
arms until the dose selection decision is made:
Arm 1: AZD0901 arm 1 IV, Q3W Arm 2: AZD0901 arm 2 IV, Q3W Arm 3: Participants in the
Investigator's choice arm, including regionally accepted chemotherapies or targeted
therapies 2L: Ramucirumab 8 mg/kg IV on Days 1 and 15 and paclitaxel 80 mg/m2 IV on Days
1, 8, and 15, Q4W 2L: Paclitaxel 80 mg/m2 IV on Days 1, 8, and 15, Q4W (for participants
with contraindication to ramucirumab only) 2L: Docetaxel 75-100 mg/m2 IV on Day 1, Q3W
(for participants with contraindication to ramucirumab only) 3L+: Irinotecan 150-180
mg/m2 IV on Days 1 and 15, Q4W 3L+: TAS-102 35 mg/m2 up to a maximum of 80 mg orally
twice a day on Days 1 to 5 and Days 8 to 12, Q4W (except China) 3L+: Apatinib 500-850 mg,
orally once daily, Q4W (China only)
Primary purpose:
Treatment
Masking:
Single (Outcomes Assessor)
Masking description:
This is an open-label study; however, it will be conducted 'sponsor-blind' and the
specific treatment to be taken by a participant will be assigned using an IRT/RTSM. To
maintain the integrity of the study, sponsor access to treatment records will be
restricted, and, in particular, under no circumstances will the sponsor undertake any
efficacy analysis by treatment arm during the study. A Study Integrity Plan will be
generated in which nominated individuals who will be granted access to any
treatment-revealing data will be pre-specified, with their reason for requiring access
detailed.
Intervention:
Intervention type:
Drug
Intervention name:
AZD0901
Description:
Participants in the AZD0901 arm 1 will receive dose level 1 AZD0901 IV
Arm group label:
AZD0901 arm 1
Intervention type:
Drug
Intervention name:
AZD0901
Description:
Participants in the AZD0901 arm 2 will receive dose level 2 AZD0901 IV
Arm group label:
AZD0901 Arm 2
Intervention type:
Drug
Intervention name:
Ramucirumab+ paclitaxel
Description:
Ramucirumab 8 mg/kg IV on Days 1 and 15 and paclitaxel 80 mg/m2 IV on Days 1, 8, and 15,
Q4W
Arm group label:
Investigator's choice arm
Intervention type:
Drug
Intervention name:
Paclitaxel
Description:
Paclitaxel 80 mg/m2 IV on Days 1, 8, and 15, Q4W (for participants with contraindication
to ramucirumab only)
Arm group label:
Investigator's choice arm
Intervention type:
Drug
Intervention name:
Docetaxel
Description:
Docetaxel 75-100 mg/m2 IV on Day 1, Q3W (for participants with contraindication to
ramucirumab only)
Arm group label:
Investigator's choice arm
Intervention type:
Drug
Intervention name:
Irinotecan
Description:
Irinotecan 150-180 mg/m2 IV on Days 1 and 15, Q4W
Arm group label:
Investigator's choice arm
Intervention type:
Drug
Intervention name:
TAS-102
Description:
TAS-102 35 mg/m2 up to a maximum of 80 mg orally twice a day on Days 1 to 5 and Days 8 to
12, Q4W (except China)
Arm group label:
Investigator's choice arm
Intervention type:
Drug
Intervention name:
Apatinib
Description:
Apatinib 500-850 mg at Investigator's discretion based on participant's condition and
tolerability, orally once daily, Q4W (China only)
Arm group label:
Investigator's choice arm
Summary:
The purpose of this study is to measure the efficacy and safety of AZD0901 compared to
Investigator's choice of therapy as 2L+ treatment for participants with advanced or
metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2.
Detailed description:
This is a Phase III, multi-center, open-label, sponsor-blinded, randomized, global study
to assess the efficacy and safety of AZD0901 compared to Investigator's choice of therapy
as the 2L+ treatment for participants with advanced or metastatic gastric or GEJ
adenocarcinoma expressing CLDN18.2, and the clinical performance of the investigational
IVD. As part of this combined approach, the efficacy analyses from this study will also
provide the basis to evaluate the clinical performance of Ventana CLDN18.2 assay as an
IVD device for the identification of patients with advanced or metastatic gastric or GEJ
adenocarcinoma expressing CLDN18.2 who may benefit from AZD0901.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
1. Capable of giving signed informed consent prior to any study procedure.
2. Participant must be at least 18 years or the legal age of consent in the
jurisdiction in which the study is taking place at the time of signing the ICF.
3. Histologically confirmed unresectable, locally advanced or metastatic adenocarcinoma
of gastric, GEJ, or distal esophagus (distal third of the esophagus) and the
following requirement:
1. Participants with positive CLDN18.2 expression from archival tumor collected
within past 24 months or from a fresh biopsy.
2. Participants must undergo local (or have had) HER2 testing by IHC/ISH.
4. Disease progression on or after at least one prior regimen for advanced or
metastatic disease, which included a fluoropyrimidine and a platinum, for advanced
or metastatic disease.
5. Must have at least one measurable or evaluable lesion assessed by the Investigator
based on RECIST 1.1.
6. ECOG performance status of 0 or 1 with no deterioration over the previous 2 weeks
prior to baseline or day of first dosing.
7. Predicted life expectancy of ≥ 12 weeks.
8. Adequate organ and bone marrow function
9. Body weight of ≥ 35 kg.
10. Sex and Contraceptive Requirements
Exclusion Criteria:
1. Participants with known HER2 positive status as defined as IHC 3+ or IHC 2+/ISH +
(Cases with HER2: CEP17 ratio ≥ 2 or an average HER2 copy number ≥ 6.0 signals/cell
are considered positive by ISH). Participants must undergo local (or have had) HER2
testing by IHC/ISH, and the most recent result of HER2 status will be used to
determine the eligibility.
2. Participant has significant or unstable gastric bleeding and/or untreated gastric
ulcers.
3. CNS metastases or CNS pathology including: epilepsy, seizures, aphasia, or stroke
within 3 months prior to consent, severe brain injury, dementia, Parkinson's
disease, neurodegenerative diseases, cerebellar disease, severe uncontrolled mental
illness, psychosis, CNS involvement of autoimmune diseases.
4. Participant has known clinically significant corneal disease (eg, active keratitis
or corneal ulcerations).
5. Persistent toxicities (CTCAE Grade ≥ 2) caused by previous anticancer therapy,
excluding alopecia. Participants with irreversible toxicity that is not reasonably
expected to be exacerbated by study intervention may be included (eg, hearing loss).
6. Prior exposure to any ADC with MMAE payload or any CLDN18.2 targeting treatment
other than naked monoclonal antibody (eg, CLDN18.2 targeting CAR-T cell therapy,
multi-specific antibody including targeting CLDN18.2, etc).
Gender:
All
Minimum age:
18 Years
Maximum age:
130 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Research Site
Address:
City:
Birmingham
Zip:
35233
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Mobile
Zip:
36604
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Tucson
Zip:
85719
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Duarte
Zip:
91010
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Fullerton
Zip:
92835
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Irvine
Zip:
92618
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Los Angeles
Zip:
90048
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Los Angeles
Zip:
90089
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Newport Beach
Zip:
92663
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Santa Rosa
Zip:
95403
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Washington
Zip:
20007
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Hollywood
Zip:
33021
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Orlando
Zip:
32803
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Atlanta
Zip:
30322
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Marietta
Zip:
30060
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Honolulu
Zip:
96819
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Boise
Zip:
83712
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lexington
Zip:
40536
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Baltimore
Zip:
21287
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Boston
Zip:
02114
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Ann Arbor
Zip:
48109
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Kansas City
Zip:
64111
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Saint Louis
Zip:
63110
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Saint Louis
Zip:
63128
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Mineola
Zip:
11501
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
New York
Zip:
10016
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
New York
Zip:
10032
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
New York
Zip:
10065
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Cincinnati
Zip:
45219
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Portland
Zip:
97239
Country:
United States
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Philadelphia
Zip:
19111
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Charlottesville
Zip:
22908
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Olympia
Zip:
98502
Country:
United States
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Seattle
Zip:
98109
Country:
United States
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Calgary
Zip:
T2N 4N2
Country:
Canada
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Barrie
Zip:
L4M 6M2
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
London
Zip:
N6C 2R5
Country:
Canada
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
North York
Zip:
M2K 1E1
Country:
Canada
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Ottawa
Zip:
K1H 8L6
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Toronto
Zip:
M5G 2M9
Country:
Canada
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Montreal
Zip:
H3G 1A4
Country:
Canada
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Beijing
Zip:
100210
Country:
China
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Changchun
Zip:
130021
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Changsha
Zip:
410013
Country:
China
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Chengdu
Zip:
610000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Chengdu
Zip:
610042
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Fuzhou City
Zip:
350001
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Fuzhou
Zip:
350014
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510060
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510120
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510655
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Guangzhou
Zip:
510700
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hangzhou
Zip:
310020
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hangzhou
Zip:
310022
Country:
China
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Harbin
Zip:
150049
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hefei
Zip:
230022
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hefei
Zip:
230031
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hefei
Zip:
230601
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Jinan
Zip:
250117
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Jining
Zip:
272029
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lanzhou
Zip:
730000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Lanzhou
Zip:
730000
Country:
China
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lishui
Zip:
323000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Luoyang
Zip:
471003
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Nanjing
Zip:
210008
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Nanjing
Zip:
210009
Country:
China
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Qingdao
Zip:
266003
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Shanghai
Zip:
200025
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Shanghai
Zip:
200032
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Shanghai
Zip:
200040
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Shenyang
Zip:
110042
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Shijiazhuang
Zip:
050011
Country:
China
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Suzhou
Zip:
215004
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Tianjin
Zip:
300060
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Urumqi
Zip:
830000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Wuhan
Zip:
430000
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Wuhan
Zip:
430030
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Xi'an
Zip:
710061
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Yinchuan
Zip:
750004
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Zhengzhou
Zip:
450003
Country:
China
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Besançon Cedex
Zip:
25030
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Brest
Zip:
29200
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lille
Zip:
59037
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lyon
Zip:
69008
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Nantes
Zip:
44000
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
PARIS Cedex 12
Zip:
75571
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Poitiers
Zip:
86021
Country:
France
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Berlin
Zip:
10249
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Berlin
Zip:
13353
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Dresden
Zip:
01067
Country:
Germany
Status:
Withdrawn
Facility:
Name:
Research Site
Address:
City:
Essen
Zip:
45136
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Frankfurt
Zip:
60488
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Göttingen
Zip:
37075
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Hamburg
Zip:
20246
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Heidelberg
Zip:
69120
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Heilbronn
Zip:
74078
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Leipzig
Zip:
04103
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Mainz
Zip:
55131
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Marburg
Zip:
35043
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Moers
Zip:
47441
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
München
Zip:
81377
Country:
Germany
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Hong Kong
Zip:
150001
Country:
Hong Kong
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hong Kong
Zip:
150001
Country:
Hong Kong
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Hong Kong
Country:
Hong Kong
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Ahmedabad
Zip:
380015
Country:
India
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Bengaluru
Zip:
560027
Country:
India
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Hyderabad
Zip:
500082
Country:
India
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Mumbai
Zip:
400012
Country:
India
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
New Delhi
Zip:
110085
Country:
India
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Florence
Zip:
50134
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Milano
Zip:
20162
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Milan
Zip:
20133
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Modena
Zip:
41124
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Napoli
Zip:
80131
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Padova
Zip:
35128
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Pisa
Zip:
56100
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Vicenza
Zip:
36100
Country:
Italy
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Fukuoka-shi
Zip:
812-8582
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Kashiwa
Zip:
227-8577
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Koto-ku
Zip:
135-8550
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Ogaki-shi
Zip:
503-8502
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Osaka-shi
Zip:
541-8567
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Sunto-gun
Zip:
411-8777
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Tokyo
Zip:
104-0045
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Toyoake-shi
Zip:
470-1192
Country:
Japan
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Yokohama-shi
Zip:
241-8515
Country:
Japan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bielsko-Biała
Zip:
43-300
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Gdańsk
Zip:
80-219
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Katowice
Zip:
40-514
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Kraków
Zip:
31-501
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lublin
Zip:
20-081
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Szczecin
Zip:
71-730
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Słupsk
Zip:
76-200
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Tomaszów Mazowiecki
Zip:
97-200
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Warszawa
Zip:
02-034
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Warszawa
Zip:
04-141
Country:
Poland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Barcelona
Zip:
08036
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Barcelona
Zip:
8035
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Madrid
Zip:
28034
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Madrid
Zip:
28041
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Orense
Zip:
32005
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Santander
Zip:
39008
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Sevilla
Zip:
41013
Country:
Spain
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Bern
Zip:
3010
Country:
Switzerland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Genève 14
Zip:
1205
Country:
Switzerland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Lausanne
Zip:
1011
Country:
Switzerland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Zürich
Zip:
8032
Country:
Switzerland
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Kaohsiung
Zip:
00807
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Kaohsiung
Zip:
83301
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taichung
Zip:
40447
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Tainan
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taipei
Zip:
10002
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taipei
Zip:
112
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Taoyuan
Zip:
333
Country:
Taiwan
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Bangkok
Zip:
10700
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Dusit
Zip:
10300
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Hat Yai
Zip:
90110
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Khon-Kaen
Zip:
40002
Country:
Thailand
Status:
Recruiting
Facility:
Name:
Research Site
Address:
City:
Cambridge
Zip:
CB2 0QQ
Country:
United Kingdom
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
London
Zip:
EC1A 7BE
Country:
United Kingdom
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
London
Zip:
SW3 6JJ
Country:
United Kingdom
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Manchester
Zip:
M20 4BX
Country:
United Kingdom
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Oxford
Zip:
OX3 7LE
Country:
United Kingdom
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Taunton
Zip:
TA1 5DA
Country:
United Kingdom
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Hanoi
Zip:
100000
Country:
Vietnam
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Ho Chi Minh city
Zip:
700000
Country:
Vietnam
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Ho Chi Minh
Zip:
700000
Country:
Vietnam
Status:
Not yet recruiting
Facility:
Name:
Research Site
Address:
City:
Vinh
Zip:
460000
Country:
Vietnam
Status:
Not yet recruiting
Start date:
March 4, 2024
Completion date:
October 9, 2026
Lead sponsor:
Agency:
AstraZeneca
Agency class:
Industry
Source:
AstraZeneca
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06346392
