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Trial Title:
PD-L1 Specific [68Ga]-Nb-1 Nanobody Probe for PET Imaging in Solid Tumors
NCT ID:
NCT06383598
Condition:
Solid Tumor
Conditions: Official terms:
Neoplasms
Fluorodeoxyglucose F18
Study type:
Interventional
Study phase:
N/A
Overall status:
Recruiting
Study design:
Allocation:
N/A
Intervention model:
Single Group Assignment
Primary purpose:
Diagnostic
Masking:
None (Open Label)
Intervention:
Intervention type:
Drug
Intervention name:
18F-FDG
Description:
All study participants will undergo one 18F-FDG PET/CT scan.
Arm group label:
68Ga-Nb-1
Summary:
The objective of the study is to constrcut a noninvasive approach 68Ga-Nb-1 PET/CT to
detect the PD-L1 expression of tumor lesions in patients with solid tumors and to
identify patients benefiting from anti-PD-L1 treatment.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
1. Aged >18 years old; ECOG 0 or 1;
2. Patients with solid tumors;
3. Has at least one measurable target lesion according to Response Evaluation Criteria
in Solid Tumors (RECIST V1.1);
4. life expectancy >=12 weeks.
Exclusion Criteria:
1. Significant hepatic or renal dysfunction;
2. Is pregnant or ready to pregnant;
3. Cannot keep their states for half an hour;
4. Refusal to join the clinical study;
5. Suffering from claustrophobia or other mental diseases;
6. Any other situation that researchers think it is not suitable to participate in the
experiment
Gender:
All
Minimum age:
18 Years
Maximum age:
70 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
Beijing Cancer Hospital
Address:
City:
Beijing
Zip:
100142
Country:
China
Status:
Recruiting
Contact:
Last name:
Hua Zhu
Phone:
+861088196495
Email:
zhuhuananjing@163.com
Start date:
May 9, 2024
Completion date:
December 2026
Lead sponsor:
Agency:
Peking University Cancer Hospital & Institute
Agency class:
Other
Source:
Peking University Cancer Hospital & Institute
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06383598
