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Trial Title:
Dynamic Whole-body PET/CT Imaging in Clinical Oncology
NCT ID:
NCT06424873
Condition:
Cancer
Study type:
Interventional
Study phase:
N/A
Overall status:
Recruiting
Study design:
Allocation:
N/A
Intervention model:
Single Group Assignment
Intervention model description:
PET/CT
Primary purpose:
Diagnostic
Masking:
None (Open Label)
Intervention:
Intervention type:
Radiation
Intervention name:
PET/CT with FDG or FES
Description:
The study consists of an additional 50 minutes of imaging during the radiotracer's uptake
phase prior to their clinical scan (standard of care).
Arm group label:
One arm study
Summary:
The goal of this clinical trial is to to achieve robust quantitative whole- body
parametric imaging in clinically feasible scan times in patient with oncologic pathology
.
The main question[s] it aims to answer are:
- [question 1]
- [question 2] Participants will [describe the main tasks participants will be asked
to do, treatments they'll be given and use bullets if it is more than 2 items].
Detailed description:
Whole body hybrid PET/CT imaging, making use of the standardized uptake value (SUV), is
well established in clinical setting for diagnosis and staging, treatment response
monitoring and radiation therapy treatment planning of a wide range of oncologic
malignancies. However, the SUV metric derived from static PET data does not capture the
dynamics of the PET probe biodistribution in the body.
The present work proposes to fill in this notable gap: namely to merge whole-body and
dynamic PET/CT imaging, to achieve robust quantitative whole- body parametric imaging in
clinically feasible scan times. Our proposed approach has the potential to significantly
enhance diagnostic, prognostic and treatment response monitoring capabilities of PET/CT
and to fundamentally alter routine clinical practice.
Criteria for eligibility:
Criteria:
Inclusion Criteria:
1. Patients clinically indicated for whole-body PET evaluation.
2. Patient must agree to lie still in the camera.
3. Patient must be able to comply with study procedures.
4. Patient must be able to provide informed consent.
Exclusion Criteria:
1. Patients < 18 years of age.
2. Pregnant women are excluded.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Geneva University Hospitals
Address:
City:
Geneva
Zip:
1205
Country:
Switzerland
Status:
Recruiting
Contact:
Last name:
Valentina Garibotto
Email:
valentina.garibotto@hcuge.ch
Start date:
April 1, 2024
Completion date:
December 31, 2025
Lead sponsor:
Agency:
Valentina Garibotto
Agency class:
Other
Source:
University Hospital, Geneva
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06424873
