= 40 % and diffusing capacity of the lung for carbon
monoxide (DLCO) >= 40 %; (3) total bilirubin <= 1.5 upper limit of normal; (4)
Alanine aminotransferase (ALT)/Aspartate aminotransferase (AST) <= 2.5 upper limit
of normal; (5) creatinine <= 1.25 upper limit of normal and creatinine clearance
rate (CCr) >= 60ml/min;
3. The first clinical diagnosis before surgery was non-small cell lung cancer,
including adenocarcinoma, squamous cell carcinoma, large cell carcinoma, and other
unknown types;
4. Clinical stage T1-2N0-1 (cI-II): Maximum diameter of tumor <= 5cm and short diameter
of mediastinal lymph node <= 1cm in thin layer CT;
5. Performance status of Eastern Cooperative Oncology Group (ECOG) 0-1;
6. All relevant examinations were completed within 28 days before the operation;
7. Patients who understand this study and have signed an approved Informed Consent.
Exclusion Criteria:
1. Patients with radiotherapy, chemotherapy, targeted therapy, or immunotherapy before
surgery.
2. Patients with the previous history of other malignancies;
3. Patients with secondary primary cancer when enrolled;
4. Patients diagnosed as pure ground glass opacity (GGO) before surgery;
5. Patients diagnosed as mixed GGO whose solid part <= 50% and Maximum diameter of
tumor <= 2cm;
6. Patients with small cell lung cancer;
7. Patients with prior unilateral open thoracic surgical procedures;
8. Woman who is pregnant or breastfeeding;
9. Patients with interstitial pneumonia, pulmonary fibrosis, or severe emphysema;
10. Patients with an active bacterial or fungal infection that is difficult to control;
11. Patients with serious psychosis;
12. Patients with a history of severe heart attack, heart failure, myocardial
infarction, or angina within the last 6 months.
Gender:
All
Minimum age:
18 Years
Maximum age:
80 Years
Healthy volunteers:
No
Locations:
Facility:
Name:
First Affiliated Hospital of Chongqing Medical University
Address:
City:
Chongqing
Zip:
400014
Country:
China
Status:
Recruiting
Contact:
Last name:
Ming Du, M.D.
Email:
Ljdyt1103@sina.com
Facility:
Name:
Gansu Provincial Hospital
Address:
City:
Lanzhou
Zip:
730000
Country:
China
Status:
Recruiting
Contact:
Last name:
Yun-Jiu Gou, M.D.
Email:
gouyunjiu@163.com
Facility:
Name:
The Second Hospital of Lanzhou University
Address:
City:
Lanzhou
Zip:
730030
Country:
China
Status:
Recruiting
Contact:
Last name:
Bin Li, M.D.
Email:
dr.leebin@qq.com
Facility:
Name:
Sun Yat-sen University Cancer Center
Address:
City:
Guangzhou
Zip:
510060
Country:
China
Status:
Recruiting
Contact:
Last name:
Hao-Xian Yang, M.D.
Phone:
+86-020-87343628
Email:
yanghx@sysucc.org.cn
Contact backup:
Last name:
Mu-Zi Yang, M.D.
Phone:
+86-020-87341456
Email:
yangmz@sysucc.org.cn
Investigator:
Last name:
Hao-Xian Yang, M.D.
Email:
Principal Investigator
Facility:
Name:
Guangdong Provincial People's Hospital
Address:
City:
Guangzhou
Zip:
510080
Country:
China
Status:
Recruiting
Contact:
Last name:
Gui-Bin Qiao, M.D.
Email:
guibinqiao@126.com
Facility:
Name:
Shenzhen People's Hospital
Address:
City:
Shenzhen
Zip:
518020
Country:
China
Status:
Recruiting
Contact:
Last name:
Guang-Suo Wang, M.D.
Email:
908611104@qq.com
Facility:
Name:
Shenzhen Third People's Hospital
Address:
City:
Shenzhen
Zip:
518112
Country:
China
Status:
Recruiting
Contact:
Last name:
Kun Qiao, M.D.
Email:
szqiaokun@163.com
Facility:
Name:
The First Affiliated Hospital of Zhengzhou University
Address:
City:
Zhengzhou
Zip:
450052
Country:
China
Status:
Recruiting
Contact:
Last name:
Yu Qi, M.D.
Email:
qiyu@zzu.edu.cn
Facility:
Name:
Wuhan Union Hospital
Address:
City:
Wuhan
Zip:
430022
Country:
China
Status:
Recruiting
Contact:
Last name:
Yong-De Liao, M.D.
Email:
liaotjxw@126.com
Facility:
Name:
Wuhan TongJi Hospital
Address:
City:
Wuhan
Zip:
430030
Country:
China
Status:
Recruiting
Contact:
Last name:
Ni Zhang, M.D.
Email:
zhangnidoc@vip.163.com
Facility:
Name:
The General Hospital of Eastern Theater Command
Address:
City:
Nanjing
Zip:
210002
Country:
China
Status:
Recruiting
Contact:
Last name:
Jun Yi, M.D.
Email:
13675101301@163.com
Facility:
Name:
Jiangsu Cancer Institute & Hospital
Address:
City:
Nanjing
Zip:
210009
Country:
China
Status:
Recruiting
Contact:
Last name:
Ming Li, M.D.
Email:
liming750523@163.com
Facility:
Name:
Jiangxi Provincial People's Hopital
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Recruiting
Contact:
Last name:
Quan Xu, M.D.
Email:
xuquan7210@163.com
Facility:
Name:
The First Affiliated Hospital of Nanchang University
Address:
City:
Nanchang
Zip:
330006
Country:
China
Status:
Recruiting
Contact:
Last name:
Ben-Tong Yu, M.D.
Email:
yubentong@126.com
Facility:
Name:
Liaoning Tumor Hospital & Institute
Address:
City:
Shenyang
Zip:
110042
Country:
China
Status:
Recruiting
Contact:
Last name:
Hong-Xu Liu, M.D.
Email:
hongxuliu@qq.com
Facility:
Name:
Tang-Du Hospital
Address:
City:
Xi'an
Zip:
710038
Country:
China
Status:
Recruiting
Contact:
Last name:
Xiao-Long Yan, M.D.
Email:
yxlfmmu@qq.com
Facility:
Name:
Qilu Hospital of Shandong University
Address:
City:
Jinan
Zip:
250012
Country:
China
Status:
Recruiting
Contact:
Last name:
Hui Tian, M.D.
Email:
tianhuiql@126.com
Facility:
Name:
Shandong Provincial Hospital
Address:
City:
Jinan
Zip:
250022
Country:
China
Status:
Recruiting
Contact:
Last name:
Zhong-Min Peng, M.D.
Email:
pengzhm@163.com
Facility:
Name:
The Affiliated Hospital of Qingdao University
Address:
City:
Qingdao
Zip:
266003
Country:
China
Status:
Recruiting
Contact:
Last name:
Wen-Jie Jiao, M.D.
Email:
jiaowj@qduhospital.cn
Facility:
Name:
Sichuan Cancer Hospital and Research Institute
Address:
City:
Chengdu
Zip:
610041
Country:
China
Status:
Not yet recruiting
Contact:
Last name:
Bin Hu, M.D.
Email:
hubin@scszlyy.org.cn
Facility:
Name:
West China Hospital
Address:
City:
Chengdu
Zip:
610041
Country:
China
Status:
Recruiting
Contact:
Last name:
Yun Wang, M.D.
Email:
2237454336@qq.com
Start date:
August 26, 2020
Completion date:
December 31, 2029
Lead sponsor:
Agency:
Sun Yat-sen University
Agency class:
Other
Collaborator:
Agency:
The First Affiliated Hospital of Nanchang University
Agency class:
Other
Collaborator:
Agency:
The Affiliated Hospital of Qingdao University
Agency class:
Other
Collaborator:
Agency:
The General Hospital of Eastern Theater Command
Agency class:
Other
Collaborator:
Agency:
Gansu Provincial Hospital
Agency class:
Other
Collaborator:
Agency:
Tang-Du Hospital
Agency class:
Other
Collaborator:
Agency:
Wuhan TongJi Hospital
Agency class:
Other
Collaborator:
Agency:
First Affiliated Hospital of Chongqing Medical University
Agency class:
Other
Collaborator:
Agency:
West China Hospital
Agency class:
Other
Collaborator:
Agency:
Wuhan Union Hospital, China
Agency class:
Other
Collaborator:
Agency:
Shenzhen People's Hospital
Agency class:
Other
Collaborator:
Agency:
The First Affiliated Hospital of Zhengzhou University
Agency class:
Other
Collaborator:
Agency:
Shandong Provincial Hospital
Agency class:
Other
Collaborator:
Agency:
Jiangsu Cancer Institute & Hospital
Agency class:
Other
Collaborator:
Agency:
Guangdong Provincial People's Hospital
Agency class:
Other
Collaborator:
Agency:
Liaoning Tumor Hospital & Institute
Agency class:
Other
Collaborator:
Agency:
Qilu Hospital of Shandong University
Agency class:
Other
Collaborator:
Agency:
Jiangxi Provincial People's Hopital
Agency class:
Other
Collaborator:
Agency:
Sichuan Cancer Hospital and Research Institute
Agency class:
Other
Collaborator:
Agency:
Lanzhou University Second Hospital
Agency class:
Other
Collaborator:
Agency:
Shenzhen Third People's Hospital
Agency class:
Other
Source:
Sun Yat-sen University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06524427
https://www.chictr.org.cn/bin/project/edit?pid=48784
