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Trial Title:
B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers
NCT ID:
NCT06536946
Condition:
Cutaneous Squamous Cell Carcinoma
Conditions: Official terms:
Carcinoma
Carcinoma, Squamous Cell
Conditions: Keywords:
B-catenin
Cutaneous squamous cell carcinoma
Immunohistochemistry
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Retrospective
Intervention:
Intervention type:
Biological
Intervention name:
Immunohistochemical staining
Description:
Staining of cutanous squamous cell carcinoma and its mimickers by monoclonal antibodies
against human B-catenin by immunohistochemical procedures
Arm group label:
Participants
Summary:
Examine the role of B-catenin in differentiation of cutaneous squamous cell carcinoma
from other lesions that may be similar to it
Detailed description:
Skin cancer is one of the most common form of cancer worldwide. Cutaneous squamous cell
carcinoma is one of most common skin tumers that caused by many factors as ultra violet
,ionizing radiation and others . It was an advanced spectrum ranging from actinic
keratosis to invasive and metastatic squmous cell carcinoma. Correct identification of
cutaneous squamous cell carcinoma is a challenge as it has both clinically and
histopathologically mimickers.
So the aim of this study is to identify the expression of B-catenin in cutaneous Squamous
cell carcinoma and its mimickers.
Criteria for eligibility:
Study pop:
archived formalin fixed parrafin embedded tissue pieces of patients of cutanous squamous
cell carcinoma and its mimickers admitted to sohag University hospital from period
juniory 2023 to June 2024
Sampling method:
Probability Sample
Criteria:
Inclusion Criteria:
- tissue blocks with sufficient materials Cases with sufficient data
Exclusion Criteria:
- tissue blocks with insufficient and necrotic materials. Casas with insufficient data
Gender:
All
Minimum age:
N/A
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Sohag University hospital
Address:
City:
Sohag
Country:
Egypt
Status:
Recruiting
Contact:
Last name:
Magdy M Amen, Professor
Contact backup:
Last name:
Nermeen S Habeeb, Doctor
Phone:
01200496394
Email:
nermin.tharwat@med.sohag.edu.eg
Start date:
June 1, 2024
Completion date:
September 30, 2025
Lead sponsor:
Agency:
Sohag University
Agency class:
Other
Source:
Sohag University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06536946
