Trial Title:
A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers
NCT ID:
NCT06541652
Condition:
Hepatocholangiocarcinoma
Fibrolamellar Carcinoma
Hepatic Epithelioid Hemangioendothelioma
Hepatoblastoma
Hepatic Neuroendocrine Carcinoma
Hepatic Carcinosarcomas
Hepatic Cystadenoma
Hepatic Leiomyosarcomas
Hepatic Angiosarcomas
Cholangiocarcinoma
Conditions: Official terms:
Carcinoma
Liver Neoplasms
Cholangiocarcinoma
Leiomyosarcoma
Carcinoma, Neuroendocrine
Carcinosarcoma
Hemangiosarcoma
Hepatoblastoma
Hemangioendothelioma
Hemangioendothelioma, Epithelioid
Cystadenoma
Conditions: Keywords:
rare primary liver cancers
LIVER
HEPATIC
COHORT
RISK FACTORS
Study type:
Observational
Overall status:
Recruiting
Study design:
Time perspective:
Other
Summary:
The aim of this French multicenter retrospective study is to describ rare primary hepatic
cancers clinical, histological and radiological features, to obtain a biological tumor
and blood collection, and to evaluate the efficacy of treatments received in clinical
practice in order to determine optimal therapeutic sequences. This retrospective cohort
will be the backbone of future translational studies aimed at identifying new molecular,
histological, circulating and radiological tumor biomarkers, potentially useful at every
stage of diagnosis and prognostic or theranostic evaluation.
Detailed description:
The aim is to describ rare primary hepatic cancers clinical, histological and
radiological features, to obtain a biological tumor and blood collection, and to evaluate
the efficacy of treatments received in clinical practice in order to determine optimal
therapeutic sequences.
Criteria for eligibility:
Study pop:
In the health centers, patients were identified in two ways:
1. via diagnoses obtained in the anatomopathology departments of each investigating
center
2. via multidisciplinary consultation meetings on primary hepatic tumours/digestive
oncology at each investigating center.
Patients with a diagnosis of rare primary hepatic cancers diagnosed on or after
01/01/2018 may be included, whether alive or deceased at the time of registration in the
CAPRIH cohort.
Sampling method:
Non-Probability Sample
Criteria:
Inclusion Criteria:
- 18 years of age or older,
- with histologically proven hepato-cholangiocarcinoma, fibrolamellar hepatocellular
carcinoma, epithelioid hemangioendothelioma or hepatic angiosarcoma
- diagnosed after January 01, 2018 living or deceased at the time of registration in
the cohort
- for living patients who have not objected to the research: (note of non-objection to
be attached° agreeing to participate in ancillary studies must sign the biological
consent form for participation in biological studies.
Exclusion Criteria:
- without social security
- No access to tumor block
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
CHU Amiens picardie
Address:
City:
Amiens
Zip:
80054
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
eric NGUYEN KHAC, MD
Facility:
Name:
Chu Angers
Address:
City:
Angers
Zip:
49933
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
FREDERIC OBERTI, MD
Facility:
Name:
Ch - Centresimone Veil de Beauvais
Address:
City:
Beauvais
Zip:
60021
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
HANIFA AMMARGUELLAT, MD
Facility:
Name:
Ch Bethune Beuvry
Address:
City:
Bethune
Zip:
62408
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
Helene VAN DAMME, MD
Facility:
Name:
Avicenne
Address:
City:
Bobigny
Zip:
93000
Country:
France
Status:
Recruiting
Contact:
Last name:
JEAN CHARLES NAULT, PR
Facility:
Name:
Chu de Clichy Hopital Beaujon
Address:
City:
Clichy
Zip:
92110
Country:
France
Status:
Recruiting
Contact:
Last name:
MOHAMED BOUATTOUR, MD
Facility:
Name:
Centre Hospitalier Universitaire Henri Mondor
Address:
City:
Creteil
Zip:
94010
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
HELENE REGNAULT, MD
Email:
helene.regnault@aphp.fr
Facility:
Name:
CHU
Address:
City:
Dijon
Zip:
21079
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
MARIANNE LATOURNERIE, MD
Facility:
Name:
Chu Grenobles Alpes
Address:
City:
La Tronche
Zip:
38700
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
BLEUENN BRUSSET, MD
Facility:
Name:
Centre Hospital Universitaire de lille
Address:
City:
Lille
Zip:
59000
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
emmanuel boleslawski, pr
Facility:
Name:
Longjumeau Ch
Address:
City:
Longjumeau
Country:
France
Status:
Recruiting
Contact:
Last name:
Manal AWAD, MD
Facility:
Name:
Ch Edouard Herriot
Address:
City:
Lyon
Zip:
69002
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
JEROME DUMORTIER, MD
Facility:
Name:
Centre Léon Berard
Address:
City:
Lyon
Zip:
69008
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
aurelien dupre
Phone:
0478782933
Email:
aurelien.dupre@lyon.unicancer.fr
Facility:
Name:
La Clinique de La Sauvegarde
Address:
City:
Lyon
Zip:
69009
Country:
France
Status:
Recruiting
Contact:
Last name:
BENJAMIN DARNIS, MD
Facility:
Name:
Hopital Saint Joseph
Address:
City:
Marseille
Zip:
13285
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
XAVIER ADHOUTE, MD
Facility:
Name:
Chu de La Timone
Address:
City:
Marseille
Zip:
13385
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
RENE GEROLAMI, MD
Facility:
Name:
CHR - Metz Thionville Hopital de Mercy
Address:
City:
Metz
Zip:
57085
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
Guillaume CONROY
Email:
g.conroy@chr-metz-thionville.fr
Facility:
Name:
Chu de Paris Saint Antoine
Address:
City:
Paris
Zip:
75571
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
MARIE LEQUOY, MD
Facility:
Name:
AP - HP - Pitié Salpêtrière
Address:
City:
Paris
Zip:
75651
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
MANON ALLAIRE, MD
Facility:
Name:
PAU CH
Address:
City:
Pau
Zip:
64000
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
JULIETTE THAURY
Phone:
0559724983
Email:
juliette.thaury@ch-pau.fr
Facility:
Name:
Centre Hospitalier de Perpignan
Address:
City:
Perpignan
Zip:
66046
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
Faiza Khemissa-Akouz, PhD
Phone:
33-4-6861-6751
Facility:
Name:
Hopital Haut Leveque
Address:
City:
Pessac
Zip:
33604
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
JEAN FREDERIC BLANC, PR
Facility:
Name:
Chu de Poitiers
Address:
City:
Poitiers
Zip:
86021
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
DAVID TOUGERON, PR
Facility:
Name:
CH - Annecy Genevois
Address:
City:
Pringy
Zip:
74374
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
emmanuel maillard, md
Facility:
Name:
Chu Robert Debre
Address:
City:
Reims
Zip:
51000
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
ELIA GIGANTE, MD
Facility:
Name:
CAC - Eugène Marquis
Address:
City:
Rennes
Zip:
35042
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
JULIEN EDELINE, MD
Facility:
Name:
Ico Site Rene Gauducheau
Address:
City:
Saint-Herblain
Zip:
44805
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
TIMOTHEE VIGNAUD, DR
Facility:
Name:
Groupe Hospitalier Rance Emeraude
Address:
City:
Saint-Malo
Zip:
35403
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
VIAUD JULIETTE, Dr
Facility:
Name:
Chru de Tours
Address:
City:
Tours
Zip:
37044
Country:
France
Status:
Not yet recruiting
Contact:
Last name:
ANAIS JAILLAIS, MD
Start date:
March 26, 2024
Completion date:
February 2031
Lead sponsor:
Agency:
Federation Francophone de Cancerologie Digestive
Agency class:
Other
Collaborator:
Agency:
Société Nationale Française de Gastroentérologie
Agency class:
Other
Source:
Federation Francophone de Cancerologie Digestive
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06541652
