Screening for Early Cervical Cancer Detection

Trial Title: Screening for Early Cervical Cancer Detection

NCT ID: NCT06550583

Condition: Cervical Cancer
Cervix Neoplasm

Conditions: Official terms:
Uterine Cervical Neoplasms

Study type: Observational

Overall status: Active, not recruiting

Study design:

Time perspective: Cross-Sectional

Intervention:

Intervention type: Diagnostic Test
Intervention name: Pap smear /Test
Description: Patients will be placed in the lithotomy position, and a sterile bivalve speculum will be inserted into the vagina. • A sample will be taken from the ectocervix by rotating a wooden Ayre spatula 360°. The sample will be quickly smeared onto a labeled glass slide and fixed with 95% ethyl alcohol in a jar to be sent to the Department of Pathology for cytopathological examination

Summary: This study is to audit results and adherence to Cervical Screening program before and after the implementing awareness of the WHO guidelines of screening among the multidisciplinary healthcare workers and patients.

Detailed description: Cervical cancer screening is the asymptomatic detection of pre-cancer and cancer in women at risk, with at least one screening suggested for women aged 30-49 years. According to the World Health Survey (2015), 19% of eligible women in developing countries and 63% of those in developed nations had their cervical cancer screening done using a Pap smear or visual inspection with acetic acid (VIA). According to latest estimates by World Health Organization (WHO), in Egypt, 866 women are diagnosed with cervical cancer every year and 373 die from the disease. Cervical cancer is the 13th most common cancer in women in Egypt and the 10th most common cancer in women aged between 15 to 44 years . Statistics from Egyptian studies provide pre invasive cervical lesion incidence levels of 0.3 % to 0.5 % . The human papillomavirus (HPV) is one of the most significant risk factors for cervical cancer. HPV can be transmitted through sexual contact, including vaginal or oral sex with an infected person. HPV has more than 100 strains, of which HPV16 and HPV18 account for about 70% of invasive cervical cancers

Criteria for eligibility:

Study pop:
Female patients who will attend gynecology clinics at Women & Children Hospital in reproductive age in (Assuit) Egypt

Sampling method: Probability Sample
Criteria:
Inclusion Criteria: - Women 20-60 years. - Sexually active. - Fulfilling Cervical Check's eligibility criteria for screening at the time of the audit https://www.cervicalcheck.ie/_fileupload/File/Eligibility%20Framework.pdf Exclusion Criteria: Patient who had underwent to total hysterectomy. - Pregnant or postpartum or post abortive patients - Patient having any history of treatment for cervical dysplasia. - Immunocompromised patients.

Gender: Female

Gender based: Yes

Gender description: sexually active women in reproductive age .

Minimum age: 20 Years

Maximum age: 60 Years

Locations:

Facility:
Name: Assiut University

Address:
City: Assiut
Zip: 71111
Country: Egypt

Start date: June 1, 2023

Completion date: September 30, 2024

Lead sponsor:
Agency: Assiut University
Agency class: Other

Source: Assiut University

Record processing date: ClinicalTrials.gov processed this data on November 12, 2024

Source: ClinicalTrials.gov page: https://clinicaltrials.gov/ct2/show/NCT06550583