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Trial Title:
Ultrasound Guided Block of Stellate Ganglion Versus Greater Occipital Nerve in Resistant Migraine and Correlation to Calcitonin Gene Related Peptide
NCT ID:
NCT06662461
Condition:
Migraine
Conditions: Official terms:
Ganglion Cysts
Migraine Disorders
Conditions: Keywords:
occipital nerve block
stellate ganglion block
migraine
Study type:
Interventional
Study phase:
N/A
Overall status:
Recruiting
Study design:
Allocation:
Randomized
Intervention model:
Parallel Assignment
Primary purpose:
Treatment
Masking:
Single (Outcomes Assessor)
Intervention:
Intervention type:
Procedure
Intervention name:
ultrasound guided Greater occipital nerve block
Description:
Patients will be positioned in a prone position with their neck slightly flexed.
The trapezius , semispinalis, obliqus capitis muscles will be revealed on short-axis
view.
A 25- or 21 gauge is used, with puncture point 1-1.5 cm away from the ultrasound probe.
Under the guidance of the ultrasound, GOB will performed by injection using 40 mg
triamcinolone and 1ml of 2% lidocaine.
Arm group label:
Ultrasound guided bilateral Greater Occipital nerve Block
Intervention type:
Procedure
Intervention name:
Ultrasound guided Stellate ganglion block
Description:
Patients are positioned in a lateral position with their necks slightly hyperextended.
Assisted by ultrasound imaging equipment the C7 level is confirmed. The thyroid gland,
carotid artery, compressible internal jugular vein, vertebral artery, brachial plexus and
the oval-shaped structure of the longus collis muscle are revealed on this short-axis
view.
A 25- or 21 gauge is used and the puncture point is 1-1.5 cm away from the ultrasound
probe The tip of the needle reach the surface of the longus collis muscle and the 5
o'clock position of the carotid artery. Under the guidance of the ultrasound, SGB is
performed by injection using 40 mg triamcinolone and 1ml of 2% lidocaine.
Arm group label:
Ultrasound guided bilateral Stellate Ganglion Block
Summary:
To investigate the efficacy of Ultrasound guided Stellate Ganglion block in chronic
resistant migraine patients in comparison to Greater Occipital Nerve Block correlating
its effect to serum CGRP level.
Detailed description:
40 Patients diagnosed with Chronic resistant migraine to 2 anti-migraine drugs for 3
months will be evaluated for inclusion and exclusion. Eligible patients with resistance
or intolerability to 2 drugs or more will be classified into two groups by using simple
randomization methods through Using a computer-generated random number sequence.
Each group will contain 20 patients one group will undergo ultrasound guided bilateral
Greater Occipital nerve Block and the other group will undergo ultrasound guided
bilateral Stellate Ganglion Block
Criteria for eligibility:
Criteria:
Inclusion Criteria:
- Individuals diagnosed with chronic resistant migraine after using or intolerability
to 2 or more of anti-migraine drugs for at least 3 months
Exclusion Criteria:
- Patients with a space-occupying lesion.
- Coagulation disorders.
- Systemic or local infection and drug allergies.
Gender:
All
Minimum age:
18 Years
Maximum age:
N/A
Healthy volunteers:
No
Locations:
Facility:
Name:
Ain Shams University Hospital
Address:
City:
Cairo
Country:
Egypt
Status:
Recruiting
Contact:
Last name:
Ass.Prof.Mai Fathy
Phone:
+2001023868846
Email:
maifathy@med.asu.edu.eg
Start date:
February 1, 2024
Completion date:
March 2025
Lead sponsor:
Agency:
Ain Shams University
Agency class:
Other
Collaborator:
Agency:
Ahmed Mohamed ElSadek
Agency class:
Other
Collaborator:
Agency:
Sherien Mohamed Farag
Agency class:
Other
Collaborator:
Agency:
Noha Lotfy Soliman
Agency class:
Other
Collaborator:
Agency:
Mohamed Amir Tork
Agency class:
Other
Collaborator:
Agency:
Ahmed Mohamed Abdelfattah Sharawy
Agency class:
Other
Source:
Ain Shams University
Record processing date:
ClinicalTrials.gov processed this data on November 12, 2024
Source: ClinicalTrials.gov page:
https://clinicaltrials.gov/ct2/show/NCT06662461
