Cancer News: Lung

Study suggests overdiagnosis in screening for lung cancer with low-dose CT

Lung cancers detected by low-dose Computed Tomography (LDCT) were over-diagnosed by 18%, according to a recent study.

Pemetrexed, paclitaxel regimens equally effective in NSCLC

For non-small cell lung cancer (NSCLC) at advanced stage, treatments with pemetrexed- and paclitaxel-based chemotherapy, have similar effectiveness but different toxicity.

Lung cancer death rates continue to fall

Statistics covering the period 1975-2010 showed death rates for lung cancer, which accounts for more than 1 in 4 cancer deaths, dropping at a faster pace than in previous years. This is likely the result of decreased cigarette smoking over many years, and is now being reflected in mortality trends.

Chest wall resection effective for recurrent mesothelioma

Patients with isolated chest wall recurrence of malignant pleural mesothelioma (MPM) have improved outcomes with salvage chest wall resection, research indicates.

Lung cancer oncogenes also drive colorectal cancer, study shows

A study shows that specific gene rearrangements known to drive subsets of lung cancer are also present in some colorectal cancers.

E-cigarettes: too soon to judge

Don't dogmatically reject e-cigarettes for fear of "renormalization" of cigarettes, one group of public health experts argued.

Lung cancer screening recommendation finalized

The recommendation includes annual low-dose Computed Tomography (CT) lung cancer screening for high-risk individuals.

Lung cancer immunity treatment under research

Lung cancer researchers are working on an alternative therapy to boost patients' immune system.

Lung cancer prevention and screening guidelines simplified

Experts are developing tools to simplify lung cancer prevention and screening recommendations.

Lung cancer treatment targeting mutated protein may be most effective

Targeted non-small cell lung cancer (NSCLC) therapies with the mutated protein KRas has been shown to be the most effective treatment strategy.

New advanced lung cancer immunotherapy shows potential

Non Small Cell Lung Cancer (NSCLC) treatment outcomes may be substantially improved through a new type of immunotherapy.

E-cigarettes may promote lung cancer in high-risk individuals

Cancerous behavior in high-risk lung cells was increased when exposed to electronic cigarette vapor in a lab setting.

Lung and bladder cancer biomarkers may share genetic disorders

Lung and bladder cancer biomarker analysis have similar genetic abnormalities. This latest research may have diagnostic, prognostic and treatment implications.

Lung cancer: antioxidants may speed up progression

An alarming finding indicates that antioxidants may speed up lung cancer’s progression, instead of halting it (as shown previously). Antioxidants are chemicals present in some pharmaceuticals, foods and nutritional supplements.

Experimental lung cancer drug improves survival in late-stage trial

The non-small cell lung cancer trial compared ramucirumab (designed to treat multiple tumors) combined with docetaxel, with a placebo combined with docetaxel.

Lung cancer treatments may result from protein discovery

A new protein has been identified as playing a key role in cancer and inflammation in lung tissue. This may help the development of new drugs for the disease.

Potential lung cancer vaccine delivers promising early results

An investigational cancer vaccine (tecemotide) combined with cisplatin chemotherapy in a trial delivered promising results for stage 3 lung cancer.

Hope in lung cancer treatment for previously untreated patients

Xalkori delayed progression of lung cancer longer than chemotherapy in patients who had never previously been treated for the disease, in a late-stage trial.

New drug promising against crizotinib-resistant lung cancer

Ceritinib appears to be effective against advanced ALK-positive non-small cell lung cancer, in tumors resistant to crizotinib & in those never treated with it.

PET scans for lung cancer can reduce unnecessary surgeries by 50%

30% of surgeries for non-small cell lung cancer were deemed unnecessary, while positron emission tomography (PET) can reduce unnecessary surgeries by 50%.

Immunotherapy in lung cancer has promising potential

Emerging lung cancer treatments will be based on drugs that can use the body's immune system to fight the disease, and prevent tumor cells from affecting it.

Non-small cell lung cancer drug delivers good results in trial

A majority of patients given a investigational drug against non-small cell lung cancer actually responded to the treatment, according to clinical trial details.

Radiotherapy for breast cancer increases risk of lung cancer

The risk of developing a primary lung tumor for women who had radiotherapy for breast cancer increases with the radiation amount, according to researchers.

Advanced lung cancer patients may benefit from chemotherapy

Among patients with advanced non-small cell lung cancer without a certain gene mutation, conventional chemotherapy resulted in longer progression-free survival.

FDA approves Ceritinib (Zykadia) for non-small cell lung cancer

The US FDA has granted accelerated approval for ceritinib (trade name: Zykadia) for treatment of a less common subtype of non-small cell lung cancer (NSCLC).

Novel lung cancer radiotherapy treatment shows success

Retreating lung tumors with radiation is an old idea that has been reintroduced, based on the technological advances in radiation oncology over the last decade.

Genomic lung cancer testing can improve targeted treatment

Targeted therapy for patients with lung adenocarcinoma can help transform treatment for the disease, as many patients have specific genetic characteristics.

Drug shrank tumors in most ALK+ non-small cell lung cancer patients

In a study, ceritinib shrank tumors in patients with ALK+ non-small cell lung cancer, regardless of prior treatment, in general.

Physical inactivity increases risk for colon, endometrial & lung cancer

Physical inactivity has been blamed for diseases like diabetes, obesity and cardiovascular disease. Now it is also linked to the risk of certain cancers.

A breath test to detect lung cancer and its stage?

A new device may accurately detect lung cancer and its stage, just by breathing into it, since it can detect specific characteristics of breath compounds.

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