Cancer News: Colon
Patients with a specific type of metastatic colorectal cancer ("KRAS exon 2 wild type") achieved longer overall survival by receiving cetuximab vs bevacizumab.
Up to 25% of colorectal cancer patients in the USA have familial risk. A new guideline recommends genetic testing for all patients newly diagnosed with the disease.
The US FDA has approved the first stool-based colorectal screening test that can detect the presence of precancerous or cancerous growths via the blood and DNA.
Colorectal cancer screening -- be it colonoscopy, sigmoidoscopy, or fecal occult-blood testing -- reduced risks of colorectal cancer mortality, researchers reported in two studies.
Aspirin's survival benefit in colon cancer correlated with the drug's antiplatelet activity but was not associated with a common tumor mutation or an enzyme linked to cancer etiology and pathogenesis, an analysis of 1,000 tumor samples showed.
(HealthDay News) -- Seniors who have minimally invasive laparoscopic surgery for colon cancer are much less likely to end up in a nursing home after being discharged from the hospital than those who have open surgery, a new study finds.
SAN DIEGO -- Annual fecal occult blood screening reduced the mortality associated with colorectal cancer by one-third, with benefits persisting over 30 years, a researcher said here.
Examining 12 major types of cancer, scientists at Washington University School of Medicine in St. Louis have identified 127 repeatedly mutated genes that appear to drive the development and progression of a range of tumors in the body. The discovery sets the stage for devising new diagnostic tools and more personalized cancer treatments.
Although screening rates for colorectal cancer rose from 2002 to 2010, more than a third of at-risk patients were not up to date with screening in 2012, according to a CDC report.
Results from a recent preclinical study have shown that a new drug combination therapy being developed effectively killed colon, liver, lung, kidney, breast and brain cancer cells while having little effect on noncancerous cells. The results lay the foundation for researchers to plan a future phase 1 clinical trial to test the safety of the therapy in a small group of patients.
Colon cancer patients who used low-dose aspirin after their diagnosis didn't see an increase in survival time, researchers found.
Researchers in Canada found that switching off a gene in the cancer stem cells that drive colon cancer stops them from being able to renew themselves. They say their study offers a starting point to treatments that could shut the cancer down.
The number of people dying from breast, prostate and bowel cancer will almost halve by 2020, new figures suggest.
Men who continued to smoke after a cancer diagnosis had an increased risk of death compared with those who quit smoking after diagnosis, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
A study shows that specific gene rearrangements known to drive subsets of lung cancer are also present in some colorectal cancers.
Erbitux is now approved to treat patients with RAS wild-type metastatic colorectal cancer by the European Commission.
A new study found that a green tea extract, when diluted in skim milk or other milk complexes, remains bioactive and continues to reduce colon cancer cell proliferation.
Screening via Computed Tomography (CT) and an antigen, each had improved rate of surgical treatment of colon cancer recurrence, compared with minimal follow-up.
Stage 2 or 3 rectal cancer patients treated with combining pre-operative radiation with either capecitabine or 5-fluorouracil (5-FU) had equivalent outcomes.
Genetic RAS mutations can help predict response to second-line treatment for metastatic colorectal cancer with panitumumab, based on a phase 3 clinical trial.
The incidence of colon cancer in older adults decreased by 30% in the last decade, coinciding with a tripling of the colonoscopy rate, in the USA.
A noninvasive, DNA-based test for colorectal cancer showed detection rates similar to colonoscopy. The test is home-based and requires no specific preparation.
Surgery for colon cancer patients has worse outcomes for those over 65, as shown in a study covering 10 years of colorectal cancer surgery information.
Researchers discovered that a drug used in combination with chemotherapy for advanced colorectal cancer may result in faster cancer progression in some cases.
Young women treated with radiation for cervical cancer have increased risk of colorectal cancer. Therefore, they should begin screening earlier than normal.
Colorectal cancer risk from eating processed meat is significantly higher in 1 in 3 people who are carriers of a common gene variant, according to new research.
Positron emission tomography (PET) scans before surgery did not significantly change the surgical treatment of colorectal cancer which has spread to the liver.
Rectal cancer patients may tolerate treatment if they receive chemotherapy before radiation therapy and surgery, as new research shows it may be more tolerable.
In a new review of past research covering 69,000 patients, sitting was associated with a higher probability of diagnosis with colon or endometrial cancer.
Physical inactivity has been blamed for diseases like diabetes, obesity and cardiovascular disease. Now it is also linked to the risk of certain cancers.