Researchers studying etoposide (used in lung & testicular cancer, leukemias and brain tumors) showed that combining it with other compounds can improve outcomes.
Young women smoking a pack a day for 10 years or more have 60% higher risk of developing the most common type of breast cancer, according to the latest study.
A small, low-cost device can help pathologists diagnose pancreatic cancer earlier and faster, as it relies on new technologies for tissue processing. It is still under development.
According to a study, early stage breast cancer patients with the BRCA gene mutation had better prognosis with a double mastectomy (compared to single mastectomy).
Intermediate & thick melanomas staged by biopsy were associated with better 10-year disease and metastasis-free survival, compared to wide excision and nodal observation. This was shown in the final results of a randomized trial.
The US FDA approved the targeted drug ibrutinib (Imbruvica) as 2nd-line treatment for patients with relapsed or refractory chronic lymphocytic leukemia (CLL).
An accurate cancer diagnosis is particularly important for rare cancers, which present additional challenges, and inaccurate diagnoses present major obstacles.
A US hospital has began treatments to prostate cancer patients whose tumor has spread to the bones, using a recently approved radioactive agent called Xofigo.
A possible explanation for relapse after hormone therapy for prostate cancer was provided by genes. This may lead to more tailored treatment for some patients.
37 out of 89 drugs previously approved tested were promising as treatment options against gastrointestinal stromal tumors (GISTs). Further tests are necessary to validate these initial outcomes.
A panel of 55 genes may predict if breast cancer will become invasive. The gene panel represents tumor suppressor & genetic alterations, and will require further testing before it could be used.
In a 25-year follow-up report from a Canadian screening program, annual mammography did not reduce breast cancer mortality in women ages 40-59. This sparked further an ongoing debate on the common practice and its effects.
Personalized treatments for bile duct cancer through genomic sequencing that could help by targeting the Epidermal Growth Factor Receptor (EGFR) are studied.
A new discovery showed that invasive bladder cancer and some breast cancers have genetic similarities. This could lead to new therapies and diagnostic aids.
99% of men after receiving proton therapy for early- and intermediate-risk prostate cancer have no evidence of disease and enjoy excellent quality of life. 76% with high-risk enjoy the same benefits.
The US FDA has approved trastuzumab emtansine (or T-DM1) for HER2-positive metastatic breast cancer treatment following trastuzumab and taxanes chemotherapy.
Chemotherapy side effects (like hair loss, nausea & fatigue) may be more manageable through specific metal implants, promising relief with future targeted drugs.
In a localized trial, a large portion of women with HPV-positive early stage cervical cancer returned to normal after being treated with the HIV drug lopinavir.
Researchers identified a protein that can be targeted for treating triple-negative breast cancer, the most aggressive form of the disease. More testing is necessary before trying this assumption in a clinical trial.
An MRI-based method may allow tumor detection without exposing young patients to radiation. This would reduce secondary cancer risk later in their lives.
Matching advanced ovarian cancer patients with one of the most common drugs (paclitaxel, cyclophosphamide, and topotecan) is now possible via gene analysis.
The non-small cell lung cancer trial compared ramucirumab (designed to treat multiple tumors) combined with docetaxel, with a placebo combined with docetaxel.
Radiation therapy on one side of the neck for advanced stage tonsil cancer resulted in good local cancer control and no recurrence on the untreated side.
Women with BRCA1 mutations should have preventive ovarian surgery (“prophylactic oophorectomy”) before they turn 35. Otherwise, their risk for cancer increases. This is the outcome of a large international study.
Researchers have developed a method for the diagnosis and prognosis of cutaneous melanoma, the type of skin cancer with the highest mortality rate.
An experimental drug known as dinaciclib could improve the effectiveness of certain multiple myeloma and myeloid leukemia therapies, according to a study.
A study of 621 adults showed that adding bevacizumab to the standard of care for glioblastoma (GBM) did not improve overall survival.
Gene mutations in men with family history of prostate cancer can identify those at high risk. This discovery can lead to active monitoring for early detection.
Genetic screening of men with a family history of prostate cancer can identify those at high risk of aggressive forms of the disease, and suggest monitoring.
Combining chemotherapy with bevacizumab (also known as Avastin) extended survival in patients with advanced cervical cancer who participated in a phase 3 trial.